Glutaraldehyde is commonly used as a biocide to disinfect delicate instruments such as dental instruments, to treat warts, hyperhidrosis and bullous diseases and as a preservative in various materials. Contact sensitivity to glutaraldehyde may not be detected, because it is not included in the standard screening chemicals recommended in the screening tests. We report a case of allergic contact dermatitis caused by Wydex(2% glutaraldehyde). A 54-year-old female made a visit to our departrnent with eczematous dermatitis of both hands, neck and face. She worked as a cleaner in delivery room and newborn nursery, and had developed the dermatitis 1 month after Wydex' containing 2% glutaraldehyde had been to clean the rooms. She had no family or personal history of atopy or contact dermatitis. Patch tests with Korean Standard(KS-1000) and Wydex were performed, and patch tests with 2% glutaraldehyde, 0.2% gluteraldehyde and rubber mix followed. The positive results were, Wydex 2% ++, 0.2% +, 0.02% + and. glutaraldehyde 2% aq. +, 0.2% aq. + on day 2 and day 4. We confirmed that the skin lesions had been caused by Wydex . The symptoms were eradicated after she changed her work environment and there has been no evidence of recurrence.
Delivery Rooms ; Dental Instruments ; Dermatitis ; Dermatitis, Allergic Contact* ; Dermatitis, Contact ; Eczema ; Female ; Glutaral* ; Hand ; Humans ; Hyperhidrosis ; Infant, Newborn ; Mass Screening ; Middle Aged ; Neck ; Nurseries ; Patch Tests ; Recurrence ; Rubber ; Skin ; Warts

We report two cases of type V hyperlipoproteinemia and eruptive xanthomas associated with diabetes mellitus in a 44-year-old woman and a 25-year-old woman. They had asymptomatic, diffuse, erythematous yellowish papules on the extremities and buttocks. The laboratory studies showed increased serum blood glucose, total cholesterol, triglyceride, increasing pre-β and chylomicron bands on electrophoresis of lipoprotein. Histopathologic findings of erythematous yellowish papules on the thigh and buttock revealed aggregation of foam cells in the dermis. They have been treated with diet control, hypoglycemic agent (gliclazide) and hypolipidemic drug (gemfibrozil), and are under continued supervision.
Adult ; Blood Glucose ; Buttocks ; Cholesterol ; Dermis ; Diabetes Mellitus* ; Diet ; Electrophoresis ; Extremities ; Female ; Foam Cells ; Humans ; Hyperlipoproteinemia Type V* ; Lipoproteins ; Organization and Administration ; Thigh ; Triglycerides ; Xanthomatosis*

No Abstract Available.

We report an extremely rare case in which two tuberculids, papulonecrotic tuberculid and erythema nodosum, occurred together. A 16-year-old girl had two types of clinically distinct lesions; asymptomatic necrotic papules on the upper and lower extremities and painful subcutaneous nodules on the legs. A Mantoux test showed a strong positive reaction. Histopathologic findings of the necrotic papule and subcutaneous nodule were consistent with papulonecrotic tuberculid and erythema nodosum, respectively. There was no extracutaneous focus of tuberculosis. Polymerase chain reaction for tuberculous bacilli in the papulonecrotic tuberculid lesion revealed a negative result. Antituberculous therapy brought a rapid clinical improvement of both lesions.
Adolescent ; Erythema Nodosum* ; Erythema* ; Female ; Humans ; Leg ; Lower Extremity ; Polymerase Chain Reaction ; Tuberculosis ; Tuberculosis, Cutaneous*

No abstract available.
Ascites* ; Female ; Ovary*

Cacinosis cutis is an uncommon disorder caused by the abnormal deposition of calcium phosphate into the skin. We report a case of calcinosis cutis affecting a 10 month-year-old infant who received many heel sticks to obtain blood for examination in a neonatal intensive care unit.
Calcinosis* ; Calcium ; Heel* ; Humans ; Infant ; Infant, Newborn ; Intensive Care, Neonatal ; Skin

Cacinosis cutis is an uncommon disorder caused by the abnormal deposition of calcium phosphate into the skin. We report a case of calcinosis cutis affecting a 10 month-year-old infant who received many heel sticks to obtain blood for examination in a neonatal intensive care unit.
Calcinosis* ; Calcium ; Heel* ; Humans ; Infant ; Infant, Newborn ; Intensive Care, Neonatal ; Skin

Aplasia cutis congenita(ACC) is a rare skin condition in which localized or widespread areas of skin are absent at birth. Clinically, lesions usually appear circular or oval, sharply outlined ulcer, resulting in healing with scarring. The most common site of this condition is scalp, especially on the vertex although other areas of the body may also be involved. Other congenital malformations have been associated with aplasia cutis congenita. Herein we report a 6-year-old male infant with round, well-marginated, smooth surfaced, brownish scar about 2 cm diameter on the vertex of scalp. The lesion was erythematous, crusted ulcer at the time of birth. Histopathologic finding of the lesion showed flattening and thinning of epidermis, fibrosis in the dermis and the absence of adnexal structures except single immature hair follicle.
Child ; Cicatrix ; Dermis ; Ectodermal Dysplasia* ; Epidermis ; Fibrosis ; Hair Follicle ; Humans ; Infant ; Male ; Parturition ; Scalp ; Skin ; Ulcer

Fibrofolliculoma is a rare benign follicular neoplasm histopathologically characterized by central dilated follicular infundibulum surrounded by well-circumscribed, thick mantle of fibrotic tissue, with anastomosing strands of follicular epithelium extending into the stroma. This condition usually occurs in multiple and rarely solitarily. Herein we report on a 34-year-old man with a solitary, skin colored, bean sized nodule on his chin which histopathologically shows a typical fibrofolliculoma.
Adult ; Chin ; Epithelium ; Humans ; Skin

Cutaneous focal mucinosis is a condition with an asymptomatic, small, dermal, white to flesh-colored papule with a predilection for the face, neck, trunk, and extremities. This is usually presented as solitary lesion but rarely as multiple papules or nodules. Histologically, a localized area of the collagen in the upper dermis is largely replaced by homogenous mucinous material in which spindle-shaped fibroblasts are scattered. We report a case of cutaneous focal mucinosis which was presented as multiple lesions covering widespread skin lesion throught the face, chest and back.
Collagen ; Dermis ; Extremities ; Fibroblasts ; Mucinoses* ; Mucins ; Neck ; Skin* ; Thorax