No abstract available.
Breast Neoplasms* ; Breast*

We investigated the distribution of S-100 protein positive dendritic cells in the skin lesions with tuberculoid sturcture. For this study, we selected the paraffin blocks of biopsied specimens with the characteristic histopathology of lupus vulgaris (5cases), tubereulosis verrucosa cutis (1 case), lupus milaris disseminatus faciei (4 cases), and erythema induratum (7 cases). The cells were identified by immunohistochemical demonstration in paraffin sections. The results were as follows: 1. S-100 protein positive dendritic cells were regularly visualized in all lesions examined. 2. S-100 protein positive dendritic cells appeared usually between the lymphohistiocytic infiltrates around the tuberculoid granulomas in contrast to the cells of monocyte-macrophage system which were within the granulomas. And they appeared occasionally (e.g. in a case of lupus vulgaris) between epitheloid cells in the granulomas. 3. S-100 protein positive dendritic cells were more numerous in the granulomatous lesions which showed the well-formed tuberculoid sturcture. From these results, we suggested the S-100 protein positive dendritic cells act as accessory cells in the pathogenesis of the granulomatous lesions by the delayed type hypersensitivity.
Dendritic Cells* ; Erythema Induratum ; Granuloma ; Hypersensitivity ; Lupus Vulgaris ; Paraffin ; S100 Proteins ; Skin*

Immunohistochemical staining was performed in 20 skin granulomas of 16 patients with leprosy using antisera against lysozyme and S-100 protein. In lepromatous leprosy, lysozyme positive cells and S-100 protein positive cells were rarely found in the dermis. However, the histoid leprosy specimen had large numbers of lysozyrne positive cells and S-100 protein positive cells in granuloma. In borderline group, lysozyme positive cells and S-l00 protein positive cells were found in the dermis. S-100 protein positive cells were diffusely distributed throughuut the granuloma in borderline lepromatous leprosy, while they were often found in lymphocytic mantle in borderline tuberculoid leprosy. In tuberculoid leprosy, lysozymal staining was encouritered in epitheloid cells and giant cells, but S-100 protein positive cells were predominantly found encircling granuloma. In the epidermis, great numbers of S-l00 protein positive cells were found in tuberculoid leprosy than in lepromatous leprosy.
Dermis ; Epidermis ; Giant Cells ; Granuloma ; Humans ; Immune Sera ; Leprosy* ; Leprosy, Lepromatous ; Leprosy, Multibacillary ; Leprosy, Paucibacillary ; Leprosy, Tuberculoid ; Muramidase* ; S100 Proteins ; Skin

High-voltage electrical burns are associated with deep muscle injuries. A hidden, deep muscle injury has no specific clinical manifestations, and undetected muscle injury sometimes leads to septisemia or major amputations. From January to December 1996, 52 burned patients were admitted to the burn center. We evaluated their laboratory findings and the results of diagnostic tools. The items of study were urine, EKG, CK-MB, CPK, LDH, SGOT, SGPT, PYP scanning, Plethysmography, and arteriography. The presence of myoglobinuria and the increase in SGOT and SGPT two weeks after the injury were related to the extent of the burns. The PYP scanning was a very sensitive and useful tool for detecting hidden muscle injuries. The arteriographic findings were unsatisfactory for deciding the amputation level. The PCR findings converting to obstructive type were helpful in predicting possibile amputations.
Alanine Transaminase ; Amputation ; Angiography ; Aspartate Aminotransferases ; Burn Units ; Burns* ; Electrocardiography ; Humans ; Myoglobinuria ; Plethysmography* ; Polymerase Chain Reaction ; Radionuclide Imaging*

No abstract available.
Cytomegalovirus* ; DNA* ; Humans* ; Polymerase Chain Reaction*

BACKGROUND: It is common practice for surgeons to place a T-tube after common bile duct exploration. T-tubes are regarded as safe and they allow postoperative cholangiography. But the unexpected cases of bile peritonitis after T-tube removal raised questions of common factors in etiology. The aim of this study is to investigate risk factors of biliary leakage after removal of T-tube from common bile duct. Materials and METHODS: Seven cases of biliary leakage after removal of T-tube have been experienced in Department of Surgery of Chonnam National University Hospital from January 1988 to March 2000. Seven cases were investigated with respect to the following parameters : presenting disease, underlying disease, laboratory findings, nutritional status, findings associate with T-tube, clinical findings and the results of treatments. RESULTS: The mean age of the patients was 62.9years(range, 45-77years). The presenting diseases were CBD stone with GB stone in three cases, CBD stone in two cases, IHBD stone in two cases. Previous medical history was unremarkable with the exceptions of one hypertensive patient and one patients with early gastric cancer concurrently undergoing treatment for hypertrophic cardiomyopathy. The mean body mass index(BMI) of the patients was 20.5. Arterial blood gas analyses and pulmonary function tests were normal. Preoperative laboratory findings were unremarkable except one patient of hypoalbuminemia. Liver function tests were normal, except in one patient with toxic hepatitis. In all cases, silastic T-tube was inserted following cholecystectomy and choledocholithotomy. The mean CBD diameter was 16.4mm (range, 12-21mm). CBD repair was done with absorbable sutures. Postoperative T-tube cholangiography revealed a remnant stone in the patients with the left intrahepatic stone and were unremarkable in all other cases. The T-tube was removed after a mean duration of 24.6days(range, 15-53). The abdomial pain and tenderness in all patients, most frequently in the right upper qudrant, was the significant sign and symptom associated with bile leakage. The symptoms resolved in four of five patients by drainage using a nelaton tube. The remaining patients(n=3) underwent reinsetion of T-tube. CONCLUSIONS: It is very difficult to predict the occurrence of bile leakage after T-tube removal. And early diagnosis and immediate percutaneous drainage make a good result in patient with localized peritonitis.
Bile* ; Blood Gas Analysis ; Cardiomyopathy, Hypertrophic ; Cholangiography ; Cholecystectomy ; Common Bile Duct* ; Drainage ; Drug-Induced Liver Injury ; Early Diagnosis ; Humans ; Hypoalbuminemia ; Jeollanam-do ; Liver Function Tests ; Nutritional Status ; Peritonitis* ; Respiratory Function Tests ; Risk Factors ; Stomach Neoplasms ; Sutures

No abstract available.
Hand*

No abstract available.
Leiomyoma*

BACKGROUND: In patients of sepsis, especially combined with multiple organ failure syndrome, the whole body oxygen consumption is delivery dependent even above the critical oxgen delivery. This phenomenon is named as 'pathologic oxygen delivery dependency'. Multiple organ failure syndrome is characterized by maldistribution of oxygen delivery, tissue oxygen diffusion disturbance and inability of oxidative phosphorylation of anaerobic metabolites owing to hepatic failure. In liver transplantation, the anhepatic phase is characterized by uneven microperfusion due to surgical manipulation and 'total hepatic failure'. We hypothesized that there might be oxygen delivery dependency in anhepatic phase of liver transplantation. METHODS: In 14 canine orthotopic liver transplantations, whole body oxygen delivery (DO2) and oxygen consumption (VO2) were calculated as the product of cardiac output and, arterial oxygen content and arterial-venous oxygen content difference, respectively, according to the operative phases. Then the relationship between DO2 and VO2 was analyzed by correlation analysis in each operative phases. RESULTS: In control and four reperfusion phases no significant correlation was found. But in two anhepatic phases (10 minutes after inferior vena cava cross clamping, 5 minutes before reperfusion), significant correlation was found (R=0.79, 0.72, p<0.005, 0.01 repectively). In postinduction phase (50 minutes after induction), significant correlation was found (R=0.62, p<0.05), but strength of correlation was lower. CONCLUSIONS: This study showed the oxygen delivery dependency in anhepatic phase of liver transplantation. Therefore supranormal oxygen supply advocated in multiple organ failure syndrome and sepsis might be applicable to management of anhepatic phase of selected recipients.
Cardiac Output ; Constriction ; Diffusion ; Humans ; Liver Failure ; Liver Transplantation* ; Liver* ; Multiple Organ Failure ; Oxidative Phosphorylation ; Oxygen Consumption* ; Oxygen* ; Reperfusion ; Sepsis ; Vena Cava, Inferior

STATEMENT OF PROBLEM: Resonance frequency analysis has been increasingly served as a noninvasive and objective method for clinical monitoring of implant stability. Many clinical studies must be required for standardized data using RFA. PURPOSE: This study was performed to evaluate RFA value changes in two anodized implant groups. MATERIAL AND METHOD: Among a total of 24 implants, twelve screw shaped implants as a test group (H2-R8.5) were manufactured, which had a pitch-height of 0.4 mm, an outer diameter of 4.3 mm, a length of 8.5 mm, and external hexa-headed, were turned from 5 mm rods of commercially pure titanium (ASTM Grade IV, Warantec Co., Seoul, Korea), and another twelve implants as a control group were Branemark Ti-Unite MK4 (diameter 4.0 mm, length 8.5 mm). Each group was installed in tibia of rabbit. Two implants were placed in each tibia (four implants per rabbit). Test two implants were inserted in right side and control two in left side. ISQ values were measured using Osstell(TM) (Integration Diagnostics Ltd. Sweden) during fixture installation, and 12 weeks later and evaluated the RFA changes. RESULTS: Mean and SD of baseline ISQ values of test group were 75.0 +/- 3.4 and 68.7 +/- 8.1 for control group. Mean and SD of ISQ values 12 weeks after implant insertion were 73.2 +/- 4.7 for test group and 72.6 +/- 3.9 for control group. There were no statistically significant differences between groups in ISQ values after 3months (P>0.05). From the data, RFA gains after 3 months were calculated, and there was statistically significant difference between groups (P<0.05). CONCLUSION: Although there were RFA changes between groups, implant stability after experimental period shows alike tendency and good bone responses.
Seoul ; Tibia ; Titanium