No abstract available.

The 16 cases of patient with Hodgkin's disease admitted to Department of Pediatrics. Yonsei Cancer Center, Collage of Medicine, Yonsei University during 15 years from January 1975 to December 1989 were reviewed on the basis of clinical charicteristics, treatment and survival rate. The results were summerized as follows. 1) The mean age of patients was 7.6 4.1(range 2~15 years of age). 2) The clinical symptoms and signs were fever (50%), cervical lymphoadenpathy (44%), weight loss(25%), night sweat sweat(19%), hepatomegaly (13%) in order. 3) The stage by Ann Arbor classification revealed Stage I (19%), Stage II (37%), Stage III (19%), stage IV (25%). 4) The histologic subtype of the 14 cases confirmed by Rye Classification revealed that mixed cellularity type (57%) was the most common and lymphocyte predominant type (28%), nodular 5) The seven patients were treated by combind modality therapy, and the six patients by chemotherapy only and the three patients by radiotherapy only. 6) Overall 5 year survival rate was 69% in all patients, and 100% in Stage I, II, 67% in Stage III, but the patients of Stage IV were all died within 7 months.
Classification ; Drug Therapy ; Fever ; Hepatomegaly ; Hodgkin Disease* ; Humans ; Lymphocytes ; Pediatrics ; Radiotherapy ; Secale ; Survival Rate ; Sweat

We report a case in an inoperable patient with the hilar malignant biliary obstruction treated palliatively by the use of a newly designed Y-shaped covered stent without interfering contra-lateral bile duct. We percutaneously inserted a newly designed Y-shaped covered stent into a biliary tree in an inoperable patient with Bismuth Type II cholangiocarcinoma. We checked tubograms, enhanced CT studies, and blood bilirubin levels before, one week after, and at every three month after the stenting, by observing closely the signs of clinical infection as well. The follow-up period was about 12 months. The placement of the Y-shaped covered stent was successful and resulted in adequate biliary drainage in the immediate post-procedural tubogram and in the follow-up abdominal CT. The serum bilirubin levels did not show elevation after the insertion of the Y-shaped covered stent.
Aged ; Bile Duct Neoplasms/pathology/radiography/*therapy ; *Bile Ducts, Intrahepatic ; Bilirubin/blood ; Cholangiocarcinoma/pathology/radiography/*therapy ; Cholangiography ; Drainage/instrumentation ; Female ; Humans ; *Palliative Care ; Prosthesis Design ; *Stents ; Tomography, X-Ray Computed

PURPOSE: Delayed treatment of congenital hypothyroidism (CH) is a common cause of mental retardation. The aim of the present study was to evaluate intellectual outcomes in preschool children with treated CH. METHODS: We retrospectively reviewed the clinical records of 43 children (age range: 13 to 60 days of life; 22 girls and 21 boys) diagnosed with CH. Children aged 5 to 7 years were examined using the Korean Wechsler Intelligence Scale for Children or the Korean Wechsler Preschool and Primary Scale of Intelligence. RESULTS: The patients started treatment between 13 and 60 days of age. The mean intelligence quotient (IQ) of patients tested at age 5 to 7 years was 103.14±11.68 (IQ range: 76–126). None had intellectual disability (defined as an IQ <70). Twenty-one subjects were treated with a low dose (6.0–9.9 µg/kg/day) and 22 with a high dose of levothyroxine (10.0–16.0 µg/kg/day). There was no significant difference in the mean full-scale IQ (FSIQ), verbal IQ (VIQ), and performance IQ (PIQ) scores between the 2 groups. FSIQ, PIQ, and VIQ scores were not significantly correlated with initial dose of L-T4, initial fT4, age at treatment in multivariate analysis. CONCLUSION: IQ scores of subjects with early treated CH diagnosed through a neonatal screening test were within normal range, regardless of etiology, thyroid function, initial dose of levothyroxine, and age at start of treatment.
Child ; Child, Preschool* ; Congenital Hypothyroidism* ; Female ; Humans ; Hypothyroidism ; Infant, Newborn ; Intellectual Disability ; Intelligence ; Multivariate Analysis ; Neonatal Screening ; Reference Values ; Retrospective Studies ; Thyroid Gland ; Thyroxine

Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large cell lymphoma, characterized by proliferation of lymphoid cells in the intravascular space of various organs without causing a mass effect. Although 18F-FDG PET is a powerful imaging tool in lymphoma, the usefulness of 18F-FDG PET in the assessment of IVLBCL is still controversial. 99mTc-MIBI, a tumor imaging radiopharmaceutical with a different mechanism from that of 18F-FDG, has been reported to be also effective in lymphoma. However, there is nearly no report on the efficacy of 99mTc-MIBI in the assessment of IVLBCL. We present one case of IVLBCL that showed 99mTc-MIBI accumulation in the involved bone marrow as an incidental finding, which was discrepant from that of 18F-FDG PET.
B-Lymphocytes ; Bone Marrow ; Fluorodeoxyglucose F18 ; Incidental Findings ; Lymphocytes ; Lymphoma ; Lymphoma, B-Cell ; Lymphoma, Large B-Cell, Diffuse

PURPOSE: The purposes of this study were to evaluate the marginal and internal gaps, and the potential clinical applications of three different methods of dental prostheses fabrication, and to compare the prostheses prepared using the silicone replica technique (SRT) and those prepared using the three-dimensional superimposition analysis (3DSA). MATERIALS AND METHODS: Five Pekkton, lithium disilicate, and zirconia crowns were each manufactured and tested using both the SRT and the two-dimensional section of the 3DSA. The data were analyzed with the nonparametric version of a two-way analysis of variance using rank-transformed values and the Tukey's post-hoc test (α = .05). RESULTS: Significant differences were observed between the fabrication methods in the marginal gap (P < .010), deep chamfer (P < .001), axial wall (P < .001), and occlusal area (P < .001). A significant difference in the occlusal area was found between the two measurement methods (P < .030), whereas no significant differences were found in the marginal gap (P > .350), deep chamfer (P > .719), and axial wall (P > .150). As the 3DSA method is three-dimensional, it allows for the measurement of arbitrary points. CONCLUSION: All of the three fabrication methods are valid for measuring clinical objectives because they produced prostheses within the clinically acceptable range. Furthermore, a three-dimensional superimposition analysis verification method such as the silicone replica technique is also applicable in clinical settings.
Crowns ; Dental Prosthesis* ; Lithium ; Methods ; Prostheses and Implants ; Replica Techniques* ; Silicon* ; Silicones*

On page 97, the second author's name has been incorrectly spelled as So Yon Lee. The correct spelling is So Won Lee.

PURPOSE: The purpose of this study is to mix dental ceramic powder in varying ratios and evaluate the effect of the mixing ratio on color and translucency. MATERIALS AND METHODS: The ceramic powder of shade A3 of the same product was mixed with the shade A2 of three products: IPS e.max Ceram (Ivoclar Vivadent, Schaan, Liechtenstein), Vintage Halo (SHOFU Inc., Kyoto, Japan), and Ceramco 3 (Ceramco-Dentsply, Burlington, NJ, USA) in the following fixed ratios (0 wt%, 25 wt%, 50 wt%, 75 wt%, and 100 wt%) and then fired. A total of 150 specimen of ceramic fired were manufactured in a regular size (W: 8.5 mm, L: 10.5 mm, and H: 1.5 mm). For color and translucency, L*, a*, and b* were measured and Two-way analysis of variance (ANOVA) and One-way analysis of variance (ANOVA) were used for data analysis (alpha=0.05). RESULTS: The higher the mixing ratio was, L*, a*, and b* of IPS e.max Ceram were all increased, and L* of Vintage Halo was reduced and a* and b* were increased. L* and a* of Ceramco3 were reduced and b* of Ceramco3 was increased. Color difference (DeltaE*ab) was increased in all three products as the mixing ratio got higher. Increased mixing ratios resulted in decreased translucency parameter (TP) values for IPS e.max Ceram but increased TP values for Vintage Halo and Ceramco3. CONCLUSION: In this limited study, CIE L*, a*, and b* were influenced by the mixing ratio of the A3 powders and porcelain powder mixtures represented a various color and translucency.
Ceramics ; Dental Porcelain* ; Fires ; Powders ; Statistics as Topic

Osteoma is benign tumor composed of mature compact or cancellous bone. Generally it is classified as periosteal(or peripheral) osteoma and endosteal(or central) osteoma by its origin. Clinically, periosteal osteoma on forehead is usually asymptomatic. From March 2002 to February 2005, We experienced 20 patients(23 cases) of histologically confirmed frontal osteoma. 20 patients are classified as sex, age, the number of osteoma, size, location and shape. Out of 20 patients, 16 were female and 4 were male in sex and mean age was 46. 18 patients have only one lesion but one patient has two lesions and another patient has three lesions. The size of osteoma varied from 7 x 5 x 3 mm to 16 x 14 x 6 mm and mean size is 12 x 10 x 5 mm. All osteomas were located at midline of forehead and shape of attachment was all sessile type. Surgical excision was superficial ostectomy through direct cutaneous incision or endoscopic approach. we obtained satisfactory result without specific complication.
Female ; Forehead ; Humans ; Male ; Osteoma*

BACKGROUND AND OBJECTIVES: Mandibulotomy approach is the most popular method for resection of oral cavity and oropharyngeal cancers because of wide surgical exposure with minimal morbidities. The purposes of this study are to evaluate the utility and morbidity of the mandibulotomy approach. SUBJECTS AND METHOD: A total of 191 patients who had cancer in the oral and oropharynx were surgically treated between 1995 and 2005. Among them, 51 patients underwent mandibulotomy. The types of the mandibular osteotomy were consisted of the paramedian osteotomy in 44 patients. RESULTS: First, only 10% (11 of 110) of the oral cavity cancer patients were required to use the mandibulotomy approach for primary resection. In the oropharynx cancer, the mandibulotomy rates was 49% (40 of 81). The rates of the mandibulotomy according to T stages were as follows: T1, 0% (0 of 27), T2; % (17/92), T3; 50% (24/48), and T4, 42% (10 of 24). Second, an average mean time to start oral diet after the mandibulotomy was 14th day and average mean duration of the tracheostomy until decannulation in the cannula was 19th days. Third, the complication rate related with the paramedian mandibulotomy related was 23% and the most of the complications could be managed with conservative treatment. CONCLUSION: The paramedian mandibulotomy with the stair-step osteotomy and miniplate fixation is an excellent surgical approach for posterior lesion of oral cavity cancer and oropharyngeal advanced tumors.
Catheters ; Diet ; Humans ; Mandible ; Mandibular Osteotomy ; Mouth* ; Oropharyngeal Neoplasms* ; Oropharynx* ; Osteotomy ; Tracheostomy