This experiment was performed to determine the stability of antiblotics in cured bone cement and the antibacterial effect with various the amount of antibiotics mixed in bone cement. Experimental animals were divided into control and antibioticimpregnated groups; 3 each for control, cloxacillin, celospor, kanamycln and panimycln groups. Antibiotic activities were measured by disk diffusion method using Staphylococcus aureus and Escherichla coli as standard organisms. The results were as follows: 1. Bone cement itself does not have antibacterial effect on the growth of Staphylococcus aureus and Escherlchia coli. Antlbiotlc impregnated acrylic bone cement showed antibacterial effects which was stable for 4 weeks. 2. In vitro test, the amount to antibiotics released In 24 hours perlod was proportional to the amount of antibiotlcs mixed in bone cement. 3. The duration of antibacterial effect was also roughly proportional to the amount of antiblotics mixed In bone cement. 4. No antibacterial effect could be measured in control groups. 4. In vivo test, the result was revealed similar patterns compared with the result of “In vitro test”, but the amounts of antibiotics released and durations of antibaterial effect was decreased. No antibacterial effect could be measured in control groups. As a result of this sutdy of this study, It is proved that the amount of antiblotics and the duratlon of antibacterial effect are proportional to the amount of antibiotics mixed in bone cemcnt. The impregnation of antiblotics in acrylic bone cement may be used to prevent and treat Infection in the orthopedic fleld.
Animals ; Anti-Bacterial Agents ; Cephacetrile ; Cloxacillin ; Diffusion ; In Vitro Techniques ; Methods ; Orthopedics ; Polymethyl Methacrylate ; Staphylococcus aureus

A tibial segment in 3cm length with vascular pedicle and periosteum (Living bone graft) and the segment without vascular pedicle and periosteum (Dead bone graft) was obtained from twenty four rabbits, being divided into two group respectively. Then it was replaced with the segmental bone in the initial osteomized defect. The grade of healing and the time factor required to accomplish the repair of resected segmental tibial transplant was determined at one week interval during one to eight weeks, aimed by the,comparative studies of microscopic (gross), radiological as well as histological observation during the healing process. The average time of callus formation in the living bone graft was approximately two weeks, as compared to four weeks of the dead bone graft. Radiographically the average time of bone union in the living bone graft was four weeks, compared with seven weeks for the dead bone graft. The living bone graft was permitted to the healing process of the simple fracture at the graft-recipient bone juncture, in the contrast with the dead bone graft it was united with replacement of the grafted bone by new bone, so called “creeping substitution”.
Bony Callus ; Periosteum ; Rabbits ; Tibia ; Time Factors ; Transplants

A case of hypertrophic interstitial neuropathy in a 32 years old man developed in the median nerve is reported. This is a rare disease characterized by thickened peripheral nerves which may be palpable and visible. This case was treated by excision of transverse carpal ligament and external and internal neurolysis.
Hereditary Sensory and Motor Neuropathy ; Ligaments ; Median Nerve ; Peripheral Nerves ; Rare Diseases

An arteriovenous fistula may be defined as a vascular abnormality in which there are one or more direct or indirect communication between an artery and a vein without any intervening capillary bed. Largely, such fistulas are divided into two groups-acquired (traumatic) or congenital in origin. There is a general agreement that congenital A-V fistula results from a failure in differentiation of the common embryonic anlage into true artery and vein. The authors have experienced a case of congenital A-V fistula formed in the 4th finger of the left hand. Such fistula is very difficult to excise completely with the conventional method. But we have obtained the excellent result by utilizing advanced meticulous microsurgical technique in excision.
Arteries ; Arteriovenous Fistula ; Capillaries ; Fingers ; Fistula ; Hand ; Methods ; Microsurgery ; Veins

During the period from May to October 1969, the authors carried out a series of tests with the aim to ascertain the present status of susceptibility of adult cockraoches to various insecticides. The tests on the susceptibility of cockroaches to dieldrin, D.D.V.P., Diazinon; Dibrom, Malathion and lindane were performed with the topical application and the residual film methods under the conditions of 26 degrees C and 80% of relative humidity. The insects tested were collected from Seoul City and were reared at the laboratory. Some of the important results so far obtained can be summarized as follows: The median lethal doses (LD(50)) of the five insecticides against female adult cockroaches were: 0.4 ug/roach or 4.02 ug/body weight (gm) by Dieldrin, 0.29/roach or 2.88 ug/body weight (gm) by D.D.V.P., 0.29 ug/roach or 2.96 ug/body weight (gm) by Diazinon, 0.54 ug/roach or 5.37 ug/body weight (gm) by Dibrom, and 2.96 ug/roach or 29.60 ug/body weight (gm) by Malathion. And those against male adult cockroaches were: 0.18 ug/roach or 3.29 ug/body weight (gm) by Dieldrin, 0.27 ug/roach or 4.89 ug/body weight (gm) by D.D.V.P., 0.16 ug/roach or 2.91 ug/body weight (gm) by Diazinon, 0.49 ug/roach or 8.97 ug/body weight (gm) by Dibrom, and 1.32 ug/roach or 24.19 ug/body weight (gm) by Malathion. The level of susceptibility of adult cockroaches to the insecticides tested was 1.0-1.6 times higher as compared with the results obtained on the Japanese Takashi strain. The median knockdown times (LT(50)) of the female adult cockroaches by insectcides at 1% concentration of 3 mg per square centimetre were 1.82 hours by Malathion, 1.36 hours by Diazinon, 0.56 hours by Lindane, 0.50 hours by Dibrom, and 2.56 hours by D.D.V.P. A marked difference was seen to exist between the males and the females. The female cockroaches were more resistant than the male to Dieldrin, Diazinon and Malathion.
parasitology-arthropoda-cockcroach-Blattella germanica ; chemotherapy ; Dieldrin ; D.D.V.P. ; Diazinon ; Dibrom ; Malathion ; lindane ; resistance

PURPOSE: The purpose of this study was to develop a prediction model for the characteristics of older adults with depression using the decision tree method. METHODS: A large dataset from the 2008 Korean Elderly Survey was used and data of 14,970 elderly people were analyzed. Target variable was depression and 53 input variables were general characteristics, family & social relationship, economic status, health status, health behavior, functional status, leisure & social activity, quality of life, and living environment. Data were analyzed by decision tree analysis, a data mining technique using SPSS Window 19.0 and Clementine 12.0 programs. RESULTS: The decision trees were classified into five different rules to define the characteristics of older adults with depression. Classification & Regression Tree (C&RT) showed the best prediction with an accuracy of 80.81% among data mining models. Factors in the rules were life satisfaction, nutritional status, daily activity difficulty due to pain, functional limitation for basic or instrumental daily activities, number of chronic diseases and daily activity difficulty due to disease. CONCLUSION: The different rules classified by the decision tree model in this study should contribute as baseline data for discovering informative knowledge and developing interventions tailored to these individual characteristics.
Activities of Daily Living ; Aged ; Aged, 80 and over ; Chronic Disease ; Data Mining ; Decision Trees ; Depression/*psychology ; Female ; Health Behavior ; Health Status ; Humans ; Leisure Activities ; Male ; Middle Aged ; Quality of Life ; Socioeconomic Factors

Mauriac syndrome consists of a triad of poorly controlled diabetes, profound growth retardation and hepatomegaly. We experienced a case of Mauriac syndrome in an 18-year-old girl who had poorly controlled diabetes mellitus, short stature, hepatomegaly and central obesity. Also at the time of examination, she had complications of diabetic cataract and nephropathy. Fourteen years prior to admission, she was diagnosed as diabetes mellitus at a hospital. Thereafter, she had been managed with irregular insulin injection. On physical examination at admission, her height was 135cm(<3 percentile) and her weight was 39kg(<3 percetile). She was short and obese. The liver was 5 cm palpable below the right subcostal margin. Her sexual maturation was Tanner stage I. On ophthalmologic examination, the cataracts were observed on both eyes and diabetic retinopathy was absent. Diabetic nephropathy could not be confirrned by kidney biopsy due to her mother's refusal. We studied the hormonal, radiographic and histological abnormalities. The hormonal study was normal and the bone age was by delayed as much as 10 years. The liver biopsy revealed glycogen accumulation in hepatocyte. She was consistent with Mauriac syndrome. She was managed by strict diabetic control with insulin therapy, diabetic diet and intensive education. She was discharged with well controlled blood glucose. Five months later, growth acceleration and sexual maturation have not been observed, but hepatomegaly subsided. (J Korean Pediatr Soc 2000;43-837-841)
Acceleration ; Adolescent ; Biopsy ; Blood Glucose ; Cataract ; Diabetes Mellitus* ; Diet, Diabetic ; Diabetic Nephropathies ; Diabetic Retinopathy ; Disulfiram ; Education ; Female ; Glycogen ; Hepatocytes ; Hepatomegaly ; Humans ; Insulin ; Kidney ; Liver ; Obesity, Abdominal ; Physical Examination ; Sexual Maturation

In the summer of 1969 from July through October, authors carried out a study of susceptibility in adult female bed bug(Cimex lectularius) in order to ascertain any development of resistance to insecticides in Korea. The test to DDT and Dieldrin was performed in laboratory by the continuous exposure of residues method, with standard impregnated paper used for adult mosqitoes. Some results so far obtained can be summarised as follows: LC(50) were 2.839% in DDT and 0.167% in Dieldrin. The resistance has been arisen 2.4-2.9 times in DDT and 1.6-2.4 times in Dieldrin as compared with London laboratory strain, but they were susceptible 1.4 times in DDT and 180 times in Dieldrin as compared to Israel resistance strain.
parasitology-arthropodology-bed bug-Cimex lectularius ; prevention ; chemotherapy ; resistance ; DDT ; dieldrin

Diagnostic angiographic evaluations were done in 33 patients with gastrointestinal bleeding for recent 5 yearsat Department of Radilogy, Seoul National University hospital. On 11 patients of them, therapeutic interventionalprocedures were made and the results were analysed. 1. In a total of 33 cases, there were 18 cases of upper GIbleeding and 15 cases of lower GI bleeding. The most frequent causes were peptic ulcer in the former andintestinal typhoid fever in the latter. 2. Bleeding sites were localized angiographically in 28 cases, so thedetection rate was 85%. Four of the five angiographically negative cases were lower GI bleeding cases. 3. The mostfrequent bleeding site was left gastric artery(7/33). The next was ileocecal branch of superior mesentericartery(6/33). 4. Among the 11 interventional procedures, Gelfoam embolization was done in 7 cases and Vasopressininfusion was tried in 4 cases. They were successful in 4 and 3 cases, suggesting 57% and 47% success ratesrespectively.
Diagnosis ; Gelatin Sponge, Absorbable ; Hemorrhage ; Humans ; Peptic Ulcer ; Seoul ; Typhoid Fever

No abstract available.
Ilizarov Technique*