1.A Case of 4P+ Syndrome.
Souck Joong YOON ; Sung Jin HONG ; Hyung Gu JO ; Dong Chul PARK
Journal of the Korean Pediatric Society 1994;37(9):1325-1329
We experinced a case of 4p+ syndrome in male infant. He had multiple anomalies such as flat occiput, hypertelorism, low set malformed ear, lower anterior hair line, depressed nose, broad nasal bridge, bilateral complete cleft lip and palate, short neck, unusual position of fingers, ventricular septal defect and umblical hernia. He menifested growth and developmental retardation. Karyotype with banding revealed an extra short arm of chromosome 4. The mother's karyotype was normal. His father and father's sister had a translocation between the short arm of chromosome 4 and the short arm of chromosome 9; their karyotypes were 46, XY, t(4;9) and 46, XX, t(4;9), respectively. In this case, trisomy 4p was the result of parental balanced translocatiom. As this is the first case in Korea, it is worthwhile to report with reviewing literature.
Arm
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Chromosomes, Human, Pair 4
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Chromosomes, Human, Pair 9
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Cleft Lip
;
Ear
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Fathers
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Fingers
;
Growth and Development
;
Hair
;
Heart Septal Defects, Ventricular
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Hernia
;
Humans
;
Hypertelorism
;
Infant
;
Karyotype
;
Korea
;
Male
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Neck
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Nose
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Palate
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Parents
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Siblings
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Trisomy
2.Role of T-lymphocyte in the heart-lung transplanted mouse.
Dae Yune JEONG ; Duck Jong HAN ; Dai Won YOON ; Soo Tong PAI ; Gu KANG ; In Chul LEE
Journal of the Korean Surgical Society 1992;43(4):489-497
No abstract available.
Animals
;
Mice*
;
T-Lymphocytes*
3.Normal Fetal Echocardiography.
Seok Joong YOON ; Sung Jin HONG ; Hyung Gu CHO ; Jung Wan YOO ; Dong Chul PARK
Journal of the Korean Pediatric Society 1994;37(5):606-611
Fetal echocardiography is used by means of decleration of fetal cardiac anaztomy, to estabilish the diagnosis of congenital heart disease in utero. We attemped fetal echocardiography to ninty three pregnant women after intra uterine period 24 weeks, and estimated cardiac circumference, cardiac axis, pulmonary atery root diameter, arortic root diameter, diameter of inferior vena cava, diameter of superior ve studied how these estimates associate with following gestational na cava, and fractional shortening of ventricles. We ages. Cardiac axis was on the average 37.28 degree and cardiac apex was located in anterior left side of chest area. Aortic root diameter was 0.227 GA-0.043mm (GA=gestational age) at systolic phase, 0.203 GA+0.421mm at diastolic phase. Pulmonaly root diameter was 0.271 GA-0.029mm at systolic phase, 0.251 GA-0.067mm at diastolic phase. Thoracic aorta diameter was 0.195 GA+0.109mm at systolic phase, 0.198 GA+0.794mm at diastolic phase. Fractional shortening was 0.24 (1 Standard Deviation=0.11) in right ventricle, 0.23(1 SD=0.154) at left ventricle, and so ratio of right and left ventricle was 1.04(1 SD=0.51). Once normal fetal cardiac anatomy is understood, structural defects and/or alternation of function can be evaluated antenatally.
Aorta, Thoracic
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Axis, Cervical Vertebra
;
Diagnosis
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Echocardiography*
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Female
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Heart Defects, Congenital
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Heart Ventricles
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Humans
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Pregnant Women
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Thorax
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Vena Cava, Inferior
4.Analysis of 35 cases of microsurgical resection and anstomosis in the management of the patjologic tubal occlusion.
Noh Hyeon PARK ; Young Chul YOO ; Chang Jae SHIN ; Jung Gu KIM ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(5):739-746
No abstract available.
Sterilization, Tubal*
5.CORRECTION OF ORIENTAL EPIBLEPHARON BY HALF A-PLASTY AND HOTZ PROCEDURE.
Sang Min LEE ; Min Gu KANG ; Jong Han CHO ; Jeoung Weon YOO ; Kun Chul YOON
Journal of the Korean Society of Aesthetic Plastic Surgery 1999;5(2):371-376
Epiblepharon is frequently encountered n oriental eyelid, especially in children. It is characterized by a horizontal fold of redundant skin and abundant orbicularis muscle near lid margin, which the lashes vertically, or posteriorly towards the eye. Surgical therapy of epiblepharon in correcting the trichiasis includes lid bracing sutures, burried sutures, skin resection, a Hotz procedure or its modification, and a Jones procedure. In our opinion, these procedures are not sufficient, because these procedures will not correct the epicanthal folds. Epicanthal folds have been a one of the characteristics of Asian over 50 percents of population in Japan and South Korea, and it either reduce the aesthetic result of the double-eyelid procedure or make the correction of the entropion and epiblepharon difficult. Although many surgical procedures are available to eliminate epicanthal folds, scarring on the medial canthus is in still and obstacle for surgeons to overcome. From January of 1998 to October of 1998, we used half z-plasty procedures in 5 cases to correct epicanthal folds in epiblepharon. There were few complications in our series. We believe that half z-plasty can get a good result in the correction of epibolepharon and oriental epicanthal folds.
Asian Continental Ancestry Group
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Braces
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Child
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Cicatrix
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Entropion
;
Eyelids
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Humans
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Japan
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Korea
;
Skin
;
Sutures
;
Trichiasis
6.Proportion of and Reason for Bevacizumab Usage in the Treatment of Wet Age-related Macular Degeneration
Yi Sang YOON ; Won Tae YOON ; Jong Woo KIM ; Chul Gu KIM ; Jae Hui KIM
Journal of the Korean Ophthalmological Society 2021;62(8):1076-1083
Purpose:
To evaluate the proportion of bevacizumab and the reason for its usage in wet age-related macular degeneration (AMD).
Methods:
Retrospective analysis of medical records was performed for 1,541 patients who received ranibizumab, aflibercept, or bevacizumab injection to treat wet AMD. The proportion of bevacizumab among the entire set of injections was identified. The reason for selecting bevacizumab was additionally identified.
Results:
During the study period, a total of 2,929 anti-vascular endothelial growth factor (anti-VEGF) injections were performed; 2,236 (76.3%) were ranibizumab or aflibercept injections and 693 (23.7%) were bevacizumab injections. The most common reason for bevacizumab usage was ‘having a 0.1 or worse best-corrected visual acuity or being unable to assure reimbursement due to the development of extensive scarring or geographic atrophy’ (297 bevacizumab injections, 42.9%). The second most common reason was ‘the inability to assure reimbursement such as extrafoveal choroidal neovascularization (CNV) or early CNV without definite fluid in the foveal region’ (201 bevacizumab injections, 29.0%).
Conclusions
Bevacizumab was used in 23.7% of the anti-VEGF injections to treat wet AMD. When analyzing patients’ treatment burden and financial impact, the results of the present study may provide useful information. Further multi-center studies are required to evaluate more precisely the usage of anti-VEGF drugs.
7.Proportion of and Reason for Bevacizumab Usage in the Treatment of Wet Age-related Macular Degeneration
Yi Sang YOON ; Won Tae YOON ; Jong Woo KIM ; Chul Gu KIM ; Jae Hui KIM
Journal of the Korean Ophthalmological Society 2021;62(8):1076-1083
Purpose:
To evaluate the proportion of bevacizumab and the reason for its usage in wet age-related macular degeneration (AMD).
Methods:
Retrospective analysis of medical records was performed for 1,541 patients who received ranibizumab, aflibercept, or bevacizumab injection to treat wet AMD. The proportion of bevacizumab among the entire set of injections was identified. The reason for selecting bevacizumab was additionally identified.
Results:
During the study period, a total of 2,929 anti-vascular endothelial growth factor (anti-VEGF) injections were performed; 2,236 (76.3%) were ranibizumab or aflibercept injections and 693 (23.7%) were bevacizumab injections. The most common reason for bevacizumab usage was ‘having a 0.1 or worse best-corrected visual acuity or being unable to assure reimbursement due to the development of extensive scarring or geographic atrophy’ (297 bevacizumab injections, 42.9%). The second most common reason was ‘the inability to assure reimbursement such as extrafoveal choroidal neovascularization (CNV) or early CNV without definite fluid in the foveal region’ (201 bevacizumab injections, 29.0%).
Conclusions
Bevacizumab was used in 23.7% of the anti-VEGF injections to treat wet AMD. When analyzing patients’ treatment burden and financial impact, the results of the present study may provide useful information. Further multi-center studies are required to evaluate more precisely the usage of anti-VEGF drugs.
8.A Case of Adeno - Squamous Cell Carcinoma Arising in Mature Cystic Teratoma.
Byoung Mok YOON ; Seog WON ; Sung Chul KANG ; Soon Chul KWON ; Hyun Lak PARK ; In Gu KANG ; Sang Eun LEE ; Tae Woo KIM ; Young Chul BAEK ; Jeung Keun PARK
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(4):422-425
Teratoma is one of germ cell tumor, common neoplasm in women of reproductive age, but it can arise at any age. Its malignant transformation is rare, less than 2%, frequently at older age. Nearly all the cases are squamous, sarcomatous and adenomatous transformation. Here we present a case of mixed transformation, adeno-squamous cell carcinoma with brief review of the concerned literature.
Carcinoma, Squamous Cell*
;
Female
;
Humans
;
Neoplasms, Germ Cell and Embryonal
;
Teratoma*
9.Labor Induction at Term with Different Regimens of Misoprostol.
Hee Joong LEE ; Chul Gu YOON ; Yong Jae YANG ; Keun Hoo LEE ; Sa Jin KIM ; Tae Chul PARK ; Jong Chul SHIN ; Jong Gu RHA ; Soo Pyung KIM
Korean Journal of Obstetrics and Gynecology 2004;47(12):2340-2344
OBJECTIVE: The purpose of this study was to compare the efficacy and the safety of two different dose regimens of intravaginal misoprostol for labor induction. METHODS: Sixty-seven consenting women with maternal or fetal indication for labor and no prior cesarean delivery were randomly assigned to receive either vaginal misoprostol 100 microgram or 50 microgram every 4 hours with maximum 6 doses. Uterine contraction, abnormal fetal heart rate pattern, mean time from induction to vaginal delivery, apgar score, and meconium staining were compaired. RESULTS: In two groups, dermographic characteristics and the average number of doses of misoprostol used were simliar. The group who were administered 100 ug misprostol showed shorter average time interval from induction to delivery. Both groups showed similiar result in terms of tachysystole, abnormal fetal heart rate tracing, meconium passage, fetal weight, low 1-min and 5-min Apgar scores, and admission to the neonatal intensive care unit. CONCLUSION: The optimal misoprostol dose to induce labor in term pregnant women has not been established. We also could not find any difference between two groups (100 microgram or 50 microgram every 4 hours) in time interval from induction to delivery and neonatal outcomes.
Apgar Score
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Female
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Fetal Weight
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Heart Rate, Fetal
;
Humans
;
Infant, Newborn
;
Intensive Care, Neonatal
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Meconium
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Misoprostol*
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Pregnancy
;
Pregnant Women
;
Uterine Contraction
10.Correlations of Postoperative Voiding Difficulty and Preoperative Urodynamic and Clinical Parameters in Stress Urinary Incontinence.
Jeong Woo YU ; Chul Yong YOON ; Jeong Gu LEE
Journal of the Korean Continence Society 2000;4(2):40-47
No abstract available in English.
Urinary Incontinence*
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Urodynamics*