Translation of terminology into Korean in the field of medicine has been one of the important tasks for the last several decades in Korea. Translation of medical terminology is deeply indebted to the Japanese scholars and direct adaptation of their work by the Korean scholars was the main trend since long time ago. This is because we share Chinese characters and the grammar structure. Although some modification and addition of new translation which is more suitable for the Korean language system has been tried in different aspects in the past editions of English-Korean medical terminology books, extensive works has been performed for the 4th edition which was published by the Korean Medical Association in 2001. The Korean Dermatological Association published the first editon of dermatology terminology book in 1983 and the 2nd edition in 1993. Many of them have been adapted in the 4th edition by the Korean Medical Association. However, many changes are noticed representing new trials with innovative ideas. This special article covers some changes of dermatological terminology between the old and new editions of terminology book published by the Korean Medical Association. Major examples are summarized in several tables.
Asian Continental Ancestry Group ; Dermatology ; Humans ; Korea

Although hepatitis B virus is usually transmitted parenterally, many cases of in fection occur in which overt parenteral contact with the virus cannot be shown. Skin is cansidered to be one route of it and there have been a few related reports recently. As Korea is one of the endemic areas of hepatitis B virus infection, I have checked HBsAg,Anti-HBs, Anti-HBc by radioimmunoassay in patients with hand eczerna to confirm other authors recent report which suggested hand skin lesion is one of the risk factors of hepatitis B virus infection. Total 41 patients were included in this study and all patients were female except one. The study results were as follows. The total prevalence rate of HBsAg was 4, 9% which is not significant different from the control. 2 The total prevalence rate kers including HBsAg was control. of the patients showed positive for one or more markers 5g 5%, which was not significant different from the contorl.
Eczema* ; Female ; Hand* ; Hepatitis B Surface Antigens ; Hepatitis B virus* ; Hepatitis B* ; Hepatitis* ; Humans ; Korea ; Prevalence ; Radioimmunoassay ; Risk Factors ; Skin

Since the foundation of Korean Contact Dermatitis Resear Group in 1980, many reports related to contact dermatitiis have been published. In this articl, 94 Korean references related to epidemiology and clinical aspect of contact dermatitis which have been published for the past 2 decades were reviewcied apers about medicaments were mos 1 equent(53) and, plants and animals(25), occupation(33), cosmetics(23), metals(19) loere in order of frequency. lhe general incidences of contact dermatitis were 5.3% 13.5% in the general out-patients. The main allergens which showed high positive rates in rovin. patch tests were a little different according to the different authors. In common allergens reckel sulfate and cobalt chloride showed increasing tendencies, while ammoniated mercury, first alldehyde, paraphenylene diamine and rubber chemicals showed decreasing tendendies. Potassiun a chromate, neomycin sulfate, and fragrance related allergens which are also commonly encountred showed variable positive rates according to the different authors. In MOHL indices less occuational and few leg ulcer cases have been observed. Obtaining informations are the key point of publication becteria, there have been more aborted studies which were presented at the annual contact dermatit ymposia in Korea, however not published.
Allergens ; Cobalt ; Dermatitis, Contact* ; Epidemiology ; Humans ; Incidence ; Korea* ; Leg Ulcer ; Neomycin ; Outpatients ; Patch Tests ; Publications ; Rubber

Fifty-five patients completed a questionaire to assess disability caused by atopic dermatitis. The eleven most relevant questions were identified and an Atopic Dermatitis Disability Index (ADDI) calculated. The index correlated with the clinical severity score (rs=0.273, 0.01 <0.05). The index may be used as a simple repeatable record of disability caused by atopic dermatitis and may potentially aid management decisions.
Dermatitis, Atopic* ; Humans

BACKGROUND: Factors that regulate hair matrix cell division within the hair follicles and control hair growth cycle have been poorly understood untill now. One of the main.causes seems to be lack of good in vitro models. OBJECTIVE: This study was performed to investigate the hair growth promoting potencies of several agents including individual components of keratinocyte growth media. METHODS: Several agents such as epidermal growth factor, insulin, bovine pituitary extract which were contained in keratinocyte growth media as well as minoxidil and transforming growth factor-α were added to the isolated anagen hair follicles. Measuring the length of hair follicle, thymidine and leucine uptake were used for hair growth parameter. RESULTS: Isolated anagen hair follicles in keratinocyte growth media showed a significant increase in length over 48 hours. [Methyl-³H] thymidine and [U-¹⁴Cl leucine uptake were sustained at basal state as well as over 48 hours and [methyl-³H] thymidine uptake increased in the matrix cells under autoradiography. Insulin with a concentration above 0.5µg/ml and transforming growth factor-α with a concentration above 10ng/ml showed a promoting effect on hair growth. However, other agents did not promote hair growth at all. CONCLUSION: Our in vitro model resembles the in vivo status of hair growth for a limited period of time and we think that normal human hair organ culture may be a useful model for developing hair growth promoting agents in vitro.
Autoradiography ; Cell Division ; Epidermal Growth Factor ; Hair Follicle* ; Hair* ; Humans ; In Vitro Techniques ; Insulin ; Intercellular Signaling Peptides and Proteins* ; Keratinocytes ; Leucine ; Minoxidil ; Organ Culture Techniques* ; Thymidine

BACKGROUND: Calcitonin gene-related peptide(CGRP)-containing nerve fibers are widely distributed in the skin including the area around hair follicles. OBJECTIVE: This study was undertaken to investigate the effect of CGRP on normal hair growth in vitro. METHODS: CGRP was added to isolated anagen hair follicles in Williams' E media or keratinocyte growth media(KGM). Measuring the length of hair follicles and thymidine uptake were used for hair growth parameters. RESULTS: CGRP-treated groups generally showed no significant difference of hair follicle length and thymidine uptake in both media compared to the controls. However, hair follicle length was significantly increased at a high concentration of CGRP in KGM compared to the controls. CONCLUSION: Our study suggested that CGRP may be a promoter of hair follicle growth in vitro.
Calcitonin Gene-Related Peptide* ; Calcitonin* ; Hair Follicle ; Hair* ; In Vitro Techniques* ; Keratinocytes ; Nerve Fibers ; Skin ; Thymidine

BACKGROUND: Several keratolytic agents have been used in many dirmatologic conditions such as callus, keratosis palmaris of plantaris, however the evaluation method of the effects of keratolytiic agents has not been good enough in clinical use. OBJECT: We have conducted an investigation to measure the effect of several keratolytic agents using an in vitro model. METHOD: We measured the fegraded protein of keratin by the bui iet method after adding enzymes such as trypsin, pepsin and papain, and irritants, salicylic acid and sodii m lauryl sulfate to the collected callus. RESULT: The order of the keratolytic effect of the enzymes was trypsir >pepsin>papain. It was difficult to detect the keratolytic effect of salicylic acid becaues of color hiidrance and there was an increasing tendency of keratolyti effect of sodium lauryl sulfate, however it was prominent mainly at a high concentration. CONCLUSION: These results suggested that the potency of similar types of keratolytic enzymes such as pepsin, trypsin and papain can be possible. However it was not such a sitable model to check the potency of the keratolytic effect of salicylic acid and the eoncentration tevel may be an important factor for certain kinds of chemicals such as sodium lauryl sulfate.
Bony Callus ; Irritants* ; Keratolytic Agents ; Keratosis ; Papain ; Pepsin A ; Salicylic Acid ; Sodium Dodecyl Sulfate ; Trypsin

The chrome content of 8 Korean cements and 11 Korean bleaching detrgents was analyzed by the qualitative DPC method and the quantitative atomic absorption spectrophotometry and UV-visible spectrophotometry. In cements, there was no detectable chrome in 1 sample and the range of chrome content in other 7 samples was 1.32 5.29ppm. The qualitative result was welJ. correlated with the quantitative result. In bleaching detergents, there was no detectable chrome in 4 samples and the range of chrome content in other 7 samples was 0.0329 0.362ppm. However, the qualitative result was not correlated with the quantitative result.
Detergents* ; Spectrophotometry ; Spectrophotometry, Atomic

The ability of nicotinic acid and its substitutes to increase cutaneous blood flow has been measured by laser Doppler flowmeter in 30 healthy human volunteers. We applied nicotinarnide, nicotinic acid ethyl ester, nicotinic acid methyl ester, hexyl nicozinate each in an acqeous solution at a concentration of 10 mM/liter for 10 minutes occlusion on the forearm. The change of blood flow was serially checked at 5 to 10 minutes intervals for one hour. The study results were as follows : l. The relative maximum cutaneous blood flow response was in following order nicotinic acid methyl ester(100%), nicotinic acid ethyl ester(98%), hexyl nicotinate (84%) and nicotinic acid(63%). However, there was no statistically significant difference(p>0.05) between each drug. There was statististically significant difference between nicotinamide and all other nicotinic acid substitutes(p<0.05). 2. The time required to reach maximum blood flow response was 6.7 minutes for hexyl nicotinste, 10 minutes for nicotinic acid ethyl ester, 12.5 minutes for nicotinic acid methyl ester and 20 minutes for nicotinic acid. However, there was statistically significant difference between hexyl nicotinate and nicotinic acid only(p<0.05). 3. Significant decrease of cutaneous blood flow was observed one hour after the removal of the patches in all drugs.
Flowmeters ; Forearm ; Healthy Volunteers ; Niacin* ; Niacinamide

No abstract available.
Acantholysis* ; Captopril* ; Penicillamine* ; Rifampin* ; Skin*