1.Observation on treating herpes zoster with compound glycyrrhiz and famciclovir
Chinese Journal of Primary Medicine and Pharmacy 2008;15(5):707-708
Objective To observe the efficacy and safety of compound glycyrrhizin and famciclovir in the treatment of herpes zoster. Methods 98 patients with herpes zoster were randomly divided into 2 groups. The treatment group were administrated with compound glycyrrhizin for a week. The control group were administrated with famciclovir for a week. The time of blister stop, crust formation, pain disappearance and cure was observed after 10 days. The rate of postherpetic neuralgia was observed too. Results The difference was significant between treatment group and control group in the time of blister stop [(2.38±0.76)d,(2.97±0.89)d], crust formation [(5.15±1.42)d, (6.91±1.97)d], pain disappearance [(4.06±1.34)d, (6.05±1.83)d] and cure [(7.32±2.21)d, (9.86±2.77)d] (all P<0.05). The difference of the rate of postherpetic neuralgia was insignificant between two groups (2%,4.2%) (P0.05). Conclusion Combined therapy of compound glycyrrhizin and famciclovir was safe and effective for the treatment of herpes zoster.
2.Hybrid therapy in patients with complex arteriosclerosis obliterans
Chuanjun LIAO ; Wangde ZHANG ; Biao YUAN
Chinese Journal of General Surgery 2014;29(8):596-599
Objective To evaluate hybrid therapy in patients with complex arteriosclerosis obliterans.Methods From Sep 2006 to Oct 2011,66 patients with complex arteriosclerosis obliterans were treated by hybrid therapy.A retrospective review was performed in all cases.Primary patency rate analyses were performed using Kaplan-Meier life tables.Results The technical success rate was 100%,and no patients died in perioperative period.12.1% patients improved 3 levels,22.7% patients improved 2 levels,and 65.2% patients improved 1 level in Fontaine grade after procedures.The average ABI before and after procedures were 0.38 and 0.67 (P < 0.05).2 patients died and other 64 patients completed 24 months follow-up.The primary patency rates and second patency rates were 75.0% and 92.2% at 24 months respectively.Primary patency rates of Fontaine Ⅱ patients were better than Fontaine Ⅲ and Ⅳ patients (P < 0.05),and primary patency rates of Fontaine Ⅲ patients were better than Fontaine Ⅳ patients (P < 0.05).Conclusions Hybrid therapy procedures provide an effective treatment in complex arteriosclerosis obliterans patients.
3.Treatment of meniscal cyst by arthroscopic partial meniscectomy and decompression of the cyst
Chuanjun ZHANG ; Tanghong JIA ; Xiuquan XI
Orthopedic Journal of China 2006;0(09):-
[Objective]To investigate the treatment and result of the meniscal cyst treatment by arthroscopic partial meniscectomy and decompression of the cyst.[Method]Nine patients who had suffered from meniscal cysts were treated by arthroscopic partial meniscectomy and decompression of the cyst in General Hospital of Yanzhou Coal Mine Group during the period from January 2002 to December 2005.There were 3 males and 6 females.The age ranged from 16 years to 54 years,with an average of(32.5?14.1) years.The duration was between 2 months and 2 years with an average of(13.4?6.8) months.One patient had medial meniscal cyst and eight patients had lateral meniscal cysts.There were 5 cysts in meniscal anterior horn,3 cysts in meniscal body and 1 cyst in meniscal posterior horn.Meniscal lesions adhering to cysts included 6 horizontal cleavages and 3 complex cleavages.Arthroscopy was performed to identify the hole through the meniscus to cyst,then the meniscal tear was partially resected taking great care to preserve the meniscal rim.The planer was used to decompress the cyst and excise the wall of the cyst and broaden the passage between the cyst and the main knee compartment.After operation,all patients were instructed to perform quadriceps exercises.The patients were followed up from 6 to 38 months with an average of(17.2?9.8) months.A conclusion was deduced from the pre-and post-operative Lysholm score of the patients.[Result]None of the 9 patients reoccored during follow-up.After operation,the symptoms of the knee pain and swelling disappeared,the range of the knee motion restored,poping and locking didn't reoccur,the fullness at the site of the cyst died away.The complication of the operation didn't occur such as infection,damage of the vascular and nerve and restriction of the knee motion.Lysholm score of the 9 patients showed a significant improvement from(70.2?7.8) pre-operation to(96.7?3.3) post-operation(t=9.3868,P=0.000).[Conclusion]Arthroscopic partial meniscectomy and cyst decompression has obvious advantages of preserving the function of the meniscus and decreasing the incidence of the knee osteoarthritis.It should be the primary treatment of the meniscal cyst owing to its low morbidity and satisfying results.
4.Quality-control testing,evaluation and application of X-ray machine's major parameters
Zuhua ZHANG ; Chuanjun WU ; Minglan WU
Chinese Medical Equipment Journal 2004;0(07):-
This paper introduces the testing methods with respect to the major parameters (X-ray tube voltage & current,exposure time,exposure volume)of X-ray machine as well as the testing results evaluation and application. It is proved that quality control of x-ray machine is an important content and technical means as to guarantee quality for radiology department of hospital.
5.Co-effects of extremely low frequency electromagnetic field (ELF-EMF) and temper-ature on hsp22 and hsp26 expression in Drosophila melanogaster
Jing ZHANG ; Ziyan ZHANG ; Chuanjun YANG ; Peng CAI
Military Medical Sciences 2014;(5):321-326
Objective To study the combined effect of extremely low frequency electromagnetic fields ( ELF-EMF ) exposure (50 Hz and 3 mT) and high temperature exposure on hsp22 and hsp26 expression in Drosophila melanogaster. Methods Under the conditions of 50 Hz and 3 mT ELF-EMF,the male and female D.melanogaster was separately exposed for 2 h at 25℃, 27.5℃, 30℃, 32.5℃,and 35℃, respectively.The death rate, exercise capacity and the hsp22 and hsp26 expression levels of D.melanogaster were detected after exposure;or at 25℃and 35℃at 2 h, 4 h, 8 h, and 24 h, respectively.The hsp22 and hsp26 expression levels of D.melanogaster were tested after exposure .Results After exposure for 2 h at 25℃, 27.5℃, 30℃, 32.5℃, and 35℃, temperature had a significant effect (P<0.01) on the death rate, exercise capacity and the hsp22 and hsp26 expression levels of D.melanogaster, but ELF-EMF had no significant effect (P>0.05).After exposure for 2 h at 25℃, 27.5℃, 30℃, 32.5℃, and 35℃, the hsp22 and hsp26 expression levels of D.melanogaster were significantly impacted(P<0.01) by gender, temperature, ELF-EMF and exposure time, and tem-perature was the most important factor .Gender, temperature, ELF-EMF and exposure time had some interaction with the results.Conclusion ELF-EMF can influence the expression levels of hsp22 and hsp26.ELF-EMF exposure contributes to heat tolerance in D.melanogaster through accelerated expression of hsp22 and hsp26.
6.Change of the declarative memory in patients with the calcification of the pallidum
Hui TONG ; Chuanjun WU ; Jianming ZHANG ; Wei HE ; Ruogu HUANG
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(2):146-148
Objective To study change of the declarative memory in patients with the calcification of the pallidum.Method The Chinese version of Wechsler Memory Scale(WMS-RC)test and dmwing forgetting curve were applied in 30 patients and 30 normal controls.Results There was no differences in the WMS-CR test's scores between the two groups.The patients had poorly memory preservation rate at the delays of 2 hours((64.10±0.87)%Vs(44.83±1.57)%,P<0.01),despite normal memory preservation rate over 30 mins and the similar slope after the delays of l day in the forgetting curve.There were negative correlations between the size of calcification and the memory preservation rate at the delays of 2 hours and 9 hours(r=-0.743,r=-0.483.P<0.01).Conclusion The results may reflect the effect of the pallidum on"slower confiolidation"declamtive memory process which aroused by a consequence of the repeated firing of hippocampal-neocortieal connections while the patients have normal memory encoding and retrieval.
7.Discussion on on-line bid of medical equipment
Yue TENG ; Bin ZHANG ; Wei FAN ; Chuanjun LI
Chinese Medical Equipment Journal 1993;0(06):-
Internet-based tendering system makes equipment purchase convenient,rapid,effective,economical and fair. This system guarantees the legal benefits of the medical organizations and suppliers to the most. At the same time this article introduces some issues that should be noticed by medical organizations and suppliers when they participate the on-line bid.
8.Application of medical equipment on-line bid system
Bin ZHANG ; Yue TENG ; Wei FAN ; Chuanjun LI
Chinese Medical Equipment Journal 2004;0(07):-
The medical equipment on-line bid is a newborn method for bid,which unites the modern computer technology,communication technology and electronic commerce technology. When the on-line bid system is applied,except for the make of comprehensive and standard tender documents,the followings also claim attention: how to correctly open the webpage of video meeting inserter,how to suitably adjust video acoustics,and how to properly adjust video images.
9.Design of sample collection system for clinical inspection
Kai SU ; Yuzhen CHENG ; Chuanjun TAO ; Erling ZHANG
Chinese Medical Equipment Journal 2004;0(08):-
This paper expounds the design of sample collection system for clinical inspection,which works as the interface of CLIS and CIS.The solution to such problems as bar-code technology,grouping application and quality insurance are discussed,and a new plan for mobile collection is suggested.
10.Efficacy and safety of ultrasound-guided upper-pole access percutaneous nephrolithotomy for the treatment of renal staghorn calculi
Gang XU ; Zhongyi LI ; Yong ZHANG ; Zhewei ZHANG ; Jimin CHEN ; Chuanjun DU
Journal of Regional Anatomy and Operative Surgery 2014;(5):471-473,474
s: Objective To investigate the efficacy and safety of ultrasound-guided upper-pole access percutaneous nephrolithotomy (PCNL) for the treatment of renal staghorn calculi. Methods From October 2008 to July 2012,193 cases of renal staghorn calculi treated with ultrasound-guided upper-pole access PCNL were reviewed. Among the 193 cases,74 cases were complete staghorn calculi while the other 119 cases were partial staghorn calculi, and the calculi diameter was 2. 5 to 9. 0 cm. All the 193 cases were treated through upper-pole ac-cess successfully,70 accesses were accomplished below the 12th rib,while the other 123 accesses were accomplished between the 11th adn 12th rib. Disintegration of the stone was accomplished using Holmium laser. Results The mean operative time was 70 min (45~150 min), single tract was used in 186 cases, and double tracts were used in the other 7 cases. The stone clearance rate for one session was 72. 0%(139/193),and the total stone clearance rate was 88. 1%(170/193). Transfusion was required in 6 patients, while 2 patients with signifi-cant bleeding were treated with selective renal arterial embolization. Hydrothorax occured in 4 patients, and closed thoracic drainage was re-quired in 2 of them. 20 patients had fever, and they recovered after effective antibiotic treatment. No patients had injury to the lung or other viscera. Conclusion Upper-pole access offers optimal visibility and convenience for rigid ureteroscope to achieve a high rate of stone-free status and operating time reduce. Ultrasound guided upper-pole access PCNL should be attempted in selected cases of renal staghorn stone.