1.Rehabilitation Effect of Synthetic Intervention on Schizophrenia
Chinese Journal of Rehabilitation Theory and Practice 2008;14(6):568-569
Objective To observe rehabilitation effect of synthetic intervention on convalescent schizophrenia.Methods 200 patients with schizophrenia in remission were randomly divided into the intervention group and control group with 100 cases in each group. The cases of the intervention group were gave synthetic intervention for 3 months but those of the control group not. All patients of two groups were evaluated with Brief Psychiatric Rating Scale (BPRS), Inpatient Psychosis Rehabilitation Observe (IPROS), Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) before and after intervention.Results Total and factor scores of every scale were not significant different between two groups before intervention ( P>0.05), but there was a significant difference after intervention, the total and factor scores of the patients of the intervention group were significantly lower than that of the control group ( P<0.01).Conclusion Synthetic intervention can improve depression and anxious symptoms of convalescent schizophrenes, elevate patients' social adaptability, promote patients recovering and returning society early.
2.Effect of Low-dose Reboxitine on Post-schizophrenic Depression:30 Cases Report
Wei JI ; Chuancai HE ; Hongbo PENG
Chinese Journal of Rehabilitation Theory and Practice 2007;13(1):90-91
ObjectiveTo explore the efficacy and side-effects of reboxitine on post-schizophrenic depression.Methods30 patients with post-schizophrenic depression according CCMD-Ⅲ accepted reboxitine 4~8 mg/d in addition to antipsychotic drugs for 6 weeks. Efficacy and side-effects were determined with Hamilton Depression Scale (HAMD), Brief Psychiatric Rating Scale (BPRS), Scale for Assessment of Negative Symptoms (SANS), Treatment Emergent Symptom Scale (TESS) before and 2, 4, 6 weeks after treatment. ResultsThe score of HAMD were obviously improved after the treatment(P<0.01), as well as that of negative psychotic symptoms in BPRS and TESS. Slight symptoms that may be associated to the Reboxitine were obvioused seldom, and all recovered without any treating. ConclusionLow-dose rebositine is effective on post-schizophrenic depression with few side-effects and good compliance.