Objective To compare the clinical efficacy of different internal fixation methods in the treatment of intertrochanteric fractures.Methods he clinical data of 270 elderly patients with intertrochanteric fracture were retrospectively analyzed.According to the different internal fixation methods,the patients were divided into three groups,namely anti-rotation intramedullary nail(PFNA) group,dynamic hip screw(DHS) group and anatomic locking plate (LCP) group,90 cases in each group.The incision length,operative time,blood loss,hospital stay,postoperative weight-bearing time,postoperative bleeding and postoperative complications were compared among the three groups.The fracture healing was compared among the three groups during follow-up.Results The incision length of PFNA group compared with the DHS group (t =11.248,P =0.000) and the LCP group (t =12.371,P =0.000),the differences were significant.The operative time of PFNA group compared with the DHS group (t =15.048,P =0.000) and the LCP group(t =12.822,P =0.000),the differences were significant.The blood loss of PFNA group compared with the DHS group (t =5.803,P =0.000) and the LCP group (t =10.879,P =0.000),the differences were significant.The incidence rates of complications in PFNA group,DHS group,LCP group were 3.33％ (3/90),10.00％ (9/90),13.33％ (12/90),respectively,and theincidence rate of PFNA group was lower than the other two groups (x2 =5.268,P =0.026).The average period of fracture healing in PFNA group compared with the DHS group (t =10.217,P =0.000) and the LCP group (t =4.530,P =0.000),the differences were significant.Conclusion PFNA in the treatment of senile intertrochanteric fractures has advantages such as less trauma,shorter operation time,less blood loss,fewer complications,faster recovery,it is worthy of clinical use.

Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Myocardial Infarction ; drug therapy ; Myocardial Reperfusion Injury ; prevention & control ; Phytotherapy ; Thrombolytic Therapy ; Urokinase-Type Plasminogen Activator ; therapeutic use

Child ; Humans ; Kidney Diseases ; etiology ; pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma ; complications ; diagnosis

Wear of polyethylene (PE) tibial inserts is a significant cause of implant failure of total knee arthroplasty (TKA). PE inserts wear measurement and evaluation is the key in TKA researches. There are many methods to measure insert wear. Qualitative methods such as observation are used to determine the wear and its type. Quantitative methods such as gravimetric analysis, coordinate measuring machines (CMM) and micro-computed tomography (micro-CT) are used to measure the mass, volume and geometry of wear. In this paper, the principle, characteristics and research progress of main insert wear evaluation method were introduced and the problems and disadvantages were analyzed.
Arthroplasty, Replacement, Knee ; Humans ; Knee Prosthesis ; Polyethylene ; Prosthesis Design ; Prosthesis Failure ; Tibia ; Tomography, X-Ray Computed ; X-Ray Microtomography

Objective To explore the effect of high dose γ-irradiation on the phenotype and function of dendritic cells (DCs) and to study the underlying mechanism of irradiation-induced immunosuppression. Methods GM-CSF and IL-4 were used to generate DCs, which were then subjected to 0, 10, 20, and 30 Gy γ irradiation. After 24 h irradiation DCs were treated with lipopolysaccharide for maturation. Then Transwell assay was used to determine the migration capacity of DCs, flow cytometry was used to detect the surface molecules on DCs (CD80, CD86, MHC-II, and CCR7). Cytokines secretion (IL-6, IL-10, and PGE2) was determined by ELISA. Resulls High dose γ-irradiation showed no influence on the phenotypes of DCs, but inhibited the migration of DCs towards CCL19. Moreover, the irradiation down-regulated CCR7 expression and decreased the secretion of IL-6, IL-10, and PGE2. Conclusion High dose γ-irradiation can inhibit DC migration by reducing CCR7 and induaing apoptoais. Moreover, it can also reduce the cytokine secretion, which provide a theoretical base for irradiation-induced immune suppression.

Objective: To investigate the chemical constituents of 80% ETOH extract from rhizome of Belamcanda chinensis (L.) DC. Methods: The constituents were isolated and purified by chromatography on silica gel, Sephadex LH-20 and HPLC; the structures of the compounds were determined by MS and NMR spectral analysis. Results: Ten constituents were identified from rhizome of Belamcanda chinensis (L.) DC, including tectoridin (I), acetovanillone (II), 4-hydroxy-acetophenone (III), β-sitosterol (IV), β-daucosterol (V), 5, 7, 4′-trihydroxyl-3′, 5′-dimethoxyflavone (VI), luteolin (VII), apigenin (VIII), 5,7,4′-trihydroxyflavanones (IX), and isorhamnetin (X). Conclusion: Compounds VI, VI, VIII, and IX have been isolated from rhizome of Belamcanda chinensis for the first time.

0.05)respectively.[Conclusion]The technique of radiographic assessment to define the anteromedial OA of the knee is not easy to perform,but it can be used,by well trained doctors,in the most knee OA cases with high accuracy.The MR imaging gives more information about cartilage defects and can be used in some doubted cases.

OBJECTIVETo observe the therapeutic effects of steel plate fixation after the failure of arthrodesis of ankle by screw fixation.

METHODSFrom August 2001 to October 2011, 15 patients were with steel plate fixation after failure of arthrodesis of ankle by screw fixation. Among patients, 9 cases were males and 6 cases were females,ranging age from 40 to 65 years old with the average of 56 years old. Ten cases were in left and 5 cases were in right. Screws were removed and steel plate was fixed intraoperatively, and plaster external fixation for postoperation. Clincal effect were evaluated according to AOFAS scoring system from pain, waliking ability and aligment before and after operation, and X-ray was used to evaluate joint fusion after operation.

RESULTSAll patients were followed up, and the duration ranged from 4 months to 4 years with an average of 2 years. The incison were healed in stage I. No ankle pain,injury of blood vessel and nerve,infection and farilure of internal fixation occuerred. The AOFAS score increased from 36.86 +/- 8.32 preoperatively to 85.09 +/- 4.65 (t = -26.366, P = 0.000).

CONCLUSIONSteel plate fixation after the failure of ankle arthrodesis of screw fixation has the advantages of rigid stability, simple manipulation and high success rate, less pain, perfect recovery.

Adult ; Aged ; Ankle Joint ; diagnostic imaging ; surgery ; Arthrodesis ; Bone Plates ; Bone Screws ; Female ; Follow-Up Studies ; Fracture Fixation, Internal ; instrumentation ; Humans ; Male ; Middle Aged ; Steel ; Tomography, X-Ray Computed ; Treatment Failure