OBJECTIVETo explore the reasons for the complications of polyacrylamide hydrogel injection.

METHODS39 patients were included in this study, who had complications after polyacrylamide hydrogel injection in the breasts, nose, temproal area or depressed locus. The clinical manifestations of the complications were analyzed.

RESULTSPostoperative infection occurred in 5 cases, induration in 23, pain in 25, ulceration of the puncture points in 9, displacement in 6, galactostasis in 1, skin necrosis in 1, breast deformation in 3, bilateral asymmetry in 4, aseptic inflammation in 10, and skin-acne-like changes on the face in 4.

CONCLUSIONSome complications were caused mainly by incorrect manipulation and others were relative to the injected material. The applications of polyacrylamide hydrogel as a clinical implant material need further investigations. Polyacrylamide hydrogel injection should be cautiously used.

Acrylic Resins ; adverse effects ; Adult ; Bacterial Infections ; etiology ; Female ; Humans ; Injections ; Middle Aged ; Pain, Postoperative ; etiology ; Postoperative Complications ; Surgery, Plastic ; adverse effects