1.Observation on clinical efficacy of warm needling moxibustion plus Mulligan dynamic joint mobilization for cervical radiculopathy
Journal of Acupuncture and Tuina Science 2017;15(6):440-445
Objective: To observe the clinical efficacy of warm needling moxibustion plus Mulligan dynamic joint mobilization for cervical radiculopathy. Methods: A total of 60 cases with cervical radiculopathy were randomly divided into group A, group B and group C by random digital table, 20 cases in each group. The patients in three groups were treated with similar warm needling moxibustion. Group A only received warm needling moxibustion; group B was treated with warm needling moxibustion plus Mulligan dynamic joint mobilization; group C was treated with warm needling moxibustion plus cervical traction. Before the treatment and after 12 sessions of treatment, the patients in the three groups were assessed for score of pain and range of motion (ROM). Results: By 12 sessions of the treatments, the scores of pain were obviously decreased in the three groups, with statistical significances (all P<0.05), and the pain scores of group B and group C were significantly different from the score of group A (both P<0.05). ROM of the neck was increased than before the treatment in the three groups, with statistical significances (all P<0.05), and the ROM of the neck of group B was significantly different from those of group A and group C (both P<0.05). Conclusion: Warm needling moxibustion plus Mulligan dynamic joint mobilization can effectively improve the neck ROM and relieve pain in patients with cervical radiculopathy.
2.Effects of different target plasma concentrations of propofol by TCI on end-tidal isoflurane concentration at BIS 50
Shirduan WANG ; Haichen CHU ; Weimin PAN
Chinese Journal of Anesthesiology 1995;0(10):-
Objective To investigate the effects of different target plasma concentrations of propofol given by TCI on end-tidal isoflurane concentration when the depth of anesthesia was maintained at BIS 50 and evaluate the reliability of electromyography (EMG) as an anesthesia depth monitor. Methods Sixty ASA Ⅰ-Ⅱ patients aged 40-65 yrs weighing 40-85 kg undergoing elective abdominal surgery under general anesthesia were randomly allocated to one of three groups with 20 patients in each group : group Ⅰ isoflurane; group Ⅱ isoflurane + TCI propofol (1 ?g?ml-1) and group Ⅲ isoflurane + TCI propofol (2 ?g?ml-1). The patients were premedicated with intramuscular phenobarbital 0.1 g and scopolamine 0.3 mg. Anesthesia was induced with midazolam 0.05 mg?kg , fentanyl 3 ?g?kg-1 and propofol 0.5-1.0 ?g?kg-1. Tracheal intubation was facilitated with vecuronium 0.12 mg?kg-1. After intubation anesthesia was maintained with isoflurane inhalation alone (group Ⅰ) or isoflurane combined with TCI propofol at a target plasma concentration of 1 ?g?ml-1 ( group Ⅱ) or 2 ?g?ml-1 ( group Ⅲ). MAP, HR, SpO2, PETCO2, BIS, EMG and end-tidal isoflurane concentration were continuously monitored during anesthesia. BIS was maintained at 45-55 after tracheal intubation during maintenance of anesthesia.Results The three groups were comparable with respect to age, sex, body weight, duration of anesthesia and the total amount of fentanyl used during anesthesia. There were no significant differences in MAP, HR and SpO2 among the 3 groups. When BIS was maintained at 50, the end-tidal isoflurane concentration was 0.76?0.03% (group Ⅰ), 0.43? 0.08% (group Ⅱ) and 0.21?0.07% (group Ⅲ) respectively. EMG was maintained at 26-29 during operation. During emergence from anesthesia EMG value increased with BIS value. When the patients opened their eyes at command EMG value was about 40. The correlation between BIS and EMG was poor. Conclusion At the samedepth of anesthesia (BIS = 50) the end-tidal isoflurane concentration was greatly reduced when combined with TCI propofol. EMG value decreases with increasing depth of anesthesia but as an anesthesia depth monitor it still needs improving.
3.The current situation and the development of good agricultural practice for Chinese crude drugs
Yue SUN ; Yang LIU ; Min FANG ; Jinong CHU ; Yanli PAN
International Journal of Traditional Chinese Medicine 2012;34(1):33-36
Good Agricultural Practice for Chinese Crude Drugs is one of the effective measures for protecting and developing resource of Chinese crude drugs..We analyzed the current situation of GAP,discussed its questions and development.
4.Analysis of the influence factors on research capacity of nursing staff
Jinlian CHENG ; Yinping CHU ; Shifan HAN ; Yangping CHAI ; Yinhe PAN
Chinese Journal of Hospital Administration 2010;26(12):934-939
Objective To identify main factors affecting the research capacity of nursing staff for efficient elevation of such a capacity. Methods 1000 persons were chosen in a random coded sampling for completion of questionnaires, including a general information questionnaire, research capacity self-assessment questionnaire, nursing professional value scale and work satisfaction scale for nursing staff. Results Main factors for the research capacity range from high to low the following: education, work satisfaction, training involvement, cognitive value, and nature of their employer. Beta values of such factors are found to be 0. 323, 0. 234, 0. 182,0. 064, and 0. 062 respectively. Conclusion Administrators of nursing staff need to focus on the development of the work values and satisfaction of nursing staff, on top of developing their research methodology and knowledge. This approach may encourage them to proactively involve in research activities.
6.The Preparation of ~99mTc-NGA for Hepatocellular Receptor Imaging and Its Predinical Study in Rabbits
Lingshan KONG ; Dengren XU ; Wenzhou PAN ; Jianxiong CHU ; Hongxun LI
Academic Journal of Second Military Medical University 1982;0(01):-
Technetium-99m galactosyl-neoglycoalbumin (99mTc-NGA) is a new hepatocellular receptor imaging ligand Its preparation and preclinical research are reported in this paper. The ligand was synthesized by the chemical coupling and the product was nontoxic and apyrogenic with good stability both in vivo and in vitro. The static images and kinetic data obtained from the liver portal vein ligation group (n = 2), the hepatic necrosis group (n=2) and the control group (n=6) indicate: (1) Tc-NGA imaging can provide excellent hepatic images, and (2) hepatic kinetic data appear to provide a new means for diagnosis of liver diseases.
7.Research Advance of Boron Removal in Reverse Osmosis Desalination
Shui-Bo WU ; Xian-Hui PAN ; Xi-Zhang CHU ;
Journal of Environment and Health 2007;0(10):-
The process mechanism and current application status of boron removal in reverse osmosis(RO)desalination were introduced.The characteristic and proper application range of eachboron removal process was summarized.Also,the running conditions of two practical desalination cases were analyzed and compared.Eventually,the future of application and the research direction of boron removal process in RO desalination were prospected.
8.The protective role of hydrogen sulfide in a mouse model of viral myocarditis induced by Coxsachie-virus B3
Lulu PAN ; Yuanhai ZHANG ; Yayan YUE ; Aihua ZHOU ; Yingying ZHANG ; Dan WANG ; Yan QIAN ; Maoping CHU
Chinese Journal of Microbiology and Immunology 2013;(9):692-699
Objective To investigate the protective role of hydrogen sulfide and the expression of cystathionine gamma-lyase/hydrogen sulfide pathway in a mouse model of myocarditis induced by Coxsachie -virus B3(CVB3).Methods A total of 110 five-week-old BALB/c male mice were randomly divided into four groups:the control group, viral myocarditis group, sodium bisulfide (NaHS) group (50 μmol/kg) and DL-propargylglycine (PAG) group (40 mg/kg).The experimental model of viral myocarditis was induced by intraperitoneal injection of CVB 3.Then the four groups were respectively administered with PBS , PBS, NaHS and PAG from day 1 to day 10 after infection.Blood and heart specimens were harvested from 10 mice of each group on day 4 and day 10 for evaluation of myocardial edema .The pathological changes in heart tis-sues were observed through hematoxylin-eosin staining.Levels of H2 S, IL-6 and TNF-αwere measured by ELISA.The expressions of CSE and CVB 3 at mRNA level were determined by quantitative real time PCR ( qRT -PCR ) analysis and the expression of CSE at protein level was detected by Western blot .Results Compared with the control group , the levels of H2 S and the expressions of CSE at mRNA and protein levels were down-regulated in mice with CVB 3-induced myocarditis .With the treatment of NaHS , the levels of H 2 S in serum and tissue were both up-regulated , and the histopathological damage was alleviated .However , PAG as an irreversible CSE inhibitor inhibited the expressions of H 2 S and CSE and aggravated myocardial injury , inflammatory cells infiltration and interstitial edema .Moreover , the RT-PCR analysis also showed that the expression of CVB3 at mRNA level was inhibited by NaHS but enhanced by PAG .Conclusion The expres-sion of CSE/H2 S pathway is down-regulated in mice with CVB 3-induced viral myocarditis .PAG could pro-mote virus propagation and exacerbate the disease through inhibiting the production of endogenous H 2 S, while NaHS as a H2 S donor has a protective effect on infected myocardium by suppressing virus replication at an early stage .
9.Development of multidimensional serf-report health measurement tool
Liuxin WU ; Dongchang QIANG ; Lüjiang SHI ; Jingfa TIAN ; Li PAN ; Junjie CHU
Chinese Journal of Health Management 2011;05(1):6-8
Objective To develop a multidimensional self-report health measurement scale for accurate evaluation of health status in Chinese adults. Methods Delphi method was used to select health measurements. Item database was set up based on available questionnaires. A total of 1858 individuals from Beijing, Hebei ,Tianjin, Shanxi and other provinces of China received field pretest. Results A self-report health assessment tool with 90 items was developed, Cronbach a coefficient of which was 0. 669 to 0. 917,split-half reliability 0. 572 to 0. 877, and test-retest reliability 0. 693 to 0. 896. Six factors from exploratory factor analysis accounted for 71.732% total variance,with the common factor>0.4. Confirmatory factor analysis showed good fit index and construct validity. Conclusion The newly developed self-rated health measurement scale ,which involves six dimensions and 90 items ,shows good reliability and validity.
10.Use of Chinese patent drugs: rationalization analysis of 1780 outpatient prescriptions in our hospital
Jialong ZHENG ; Jinong CHU ; Yanli PAN ; Renfang YIN ; Yibin WANG ; Guofeng DUAN
International Journal of Traditional Chinese Medicine 2012;(12):1073-1074
Objective To Analyze the proprietary usage of Chinese medicine prescriptions in our hospital and to improve the level of rational drug use.Methods 1780 prescriptions were randomly collected from our hospital during January to June,2011 and analyzed.Results The rational prescriptions had a 83.01% share in the whole.while the irrational prescriptions had a 21.2% share in the whole,among which 13.37% were unqualified writing,3.45% were irrational drug use.The irrationality mainly manifested as missing items in the prescription,and improper usage and dosage.Conclusion It is suggested to strengthen the awareness of physicians on standard prescription writing,strict pharmacist review,and establish prescription quality management system to improve the quality of prescription.