Angiolymphoid hyperplasia with eosinophilia(ALHE) is a benign angiomatous neoplasm which usually arises from skin, blood vessel, soft tissue, heart and rarely from bone. The authors experienced a case of ALHE which involved the distal femur of 35-years old male and treated by marginal excision and autogenous cancellous bone graft with plate fixation.
Angiolymphoid Hyperplasia with Eosinophilia ; Blood Vessels ; Femur ; Heart ; Humans ; Hyperplasia ; Male ; Skin ; Transplants

The authors report a case of infection with Thelazia callipaeda in a Korean man. The patient was a 47 year-old man. He experienced epiphora and foreign body sensation of the right eye since 3 weeks ago. Total of 2 worms were removed from the conjunctival sac; one by himself 1 day prior to examination and the other by an ophthalmologist. The worm was slender creamy white in color which was fixed in a 10% formaline solution. The worm was 17.38 mm in length, 0.45 mm in body width, 0.026 mm in length of buccal cavity, 0.63 mm in length of anterior end to vaginal opening, 0.76 mm in length of anterior end to the esophagointestinal junction and 0.06 mm in length of posterior end to the anus. There were numerous striations on surface of worms and vaginal opening was located anterior to the esophagointestinal junction. Based on aforementioned findings, it was confirmed as a female worm of Thelazia callipaeda, and the authors report it with literature.
Anal Canal ; Female ; Foreign Bodies ; Formaldehyde ; Humans* ; Lacrimal Apparatus Diseases ; Middle Aged ; Sensation ; Thelazioidea

The authors report a case of infection with Thelazia callipaeda in a Korean man. The patient was a 47 year-old man. He experienced epiphora and foreign body sensation of the right eye since 3 weeks ago. Total of 2 worms were removed from the conjunctival sac; one by himself 1 day prior to examination and the other by an ophthalmologist. The worm was slender creamy white in color which was fixed in a 10% formaline solution. The worm was 17.38 mm in length, 0.45 mm in body width, 0.026 mm in length of buccal cavity, 0.63 mm in length of anterior end to vaginal opening, 0.76 mm in length of anterior end to the esophagointestinal junction and 0.06 mm in length of posterior end to the anus. There were numerous striations on surface of worms and vaginal opening was located anterior to the esophagointestinal junction. Based on aforementioned findings, it was confirmed as a female worm of Thelazia callipaeda, and the authors report it with literature.
Anal Canal ; Female ; Foreign Bodies ; Formaldehyde ; Humans* ; Lacrimal Apparatus Diseases ; Middle Aged ; Sensation ; Thelazioidea

BACKGROUND: Heat tobacco products (HTPs) are emerging in Korea. There are few studies that investigated the rates of HTPs use among military personnel in Korea. This study was performed to identify the prevalence of HTPs experience and use. Also this study aimed to evaluate the related factors of HTPs experience and use among military personnel in Korea.METHODS: The study subjects were 3,878 military personnel participated health survey for Korean soldiers from November to December in 2018. Binominal logistic regression analysis was performed to confirm the related factors of HTPs experience and use among military personnel in Korea.RESULTS: The HTPs experience and current use rates of study subjects were 17.4% and 8.7%, respectively. And the HTPs experience and current use among military personnel was associated with college/university degree (adjusted odds ratio [aOR] 1.441, 1.377), lance-corporal (aOR 2.049, 5.636), superiors' smoking in military camp (aOR 1.516, 1.567), interest in health (aOR 1.637, 1.571), ever used smoking (aOR 2.817, 3.575), and ever used electronic cigarette (E-cigarette) (aOR 3.129, 1.587).CONCLUSIONS: The HTPs experience and current use among military personnel are closely related to educational level, military level, smoking status of the superiors, interests in health, conventional cigarette smoking, and E-cigarette use.
Electronic Cigarettes ; Health Surveys ; Hot Temperature ; Humans ; Korea ; Logistic Models ; Military Personnel ; Odds Ratio ; Prevalence ; Smoke ; Smoking ; Tobacco Products ; Tobacco

BACKGROUND: Microalbuminuria (MA) is a predictor for diabetic nephropathy and mortality of cardiovascular disease. Diabetic nephropathy can be prevented by blood glucose and blood pressure control. Koreans have been found to have a significantly higher risk of type 2 diabetes than Caucasians, despite having normal weights. It is necessary to consider obesity status in the prevention of type 2 diabetes. This study aimed to determine the relationship between MA and hypertension according to obesity status in prediabetes.METHODS: This study was retrospectively conducted in 1,183 prediabetes, aged 30-70 years with fasting blood glucose levels of 100-125 mg/dL or hemoglobin A1c levels of 5.7–6.4% who health examinees at 16 health promotion centers from 2015 to 2016. Study subjects were classified according to obesity and hypertension. Obesity is defined as body mass index of ≥25 kg/m². Blood pressure was categorized as follows: normal blood pressure, <120/80 mmHg; prehypertension, 120–139/80–89 mmHg; and hypertension, ≥140/90 mmHg. We analyzed the relationship between MA and hypertension according to obesity using multivariable logistic regression analysis.RESULTS: While both prehypertensive and hypertensive subgroups were significantly associated with MA in the nonobese, the hypertensive subgroup was only associated with MA in the obese. In the combined effects of obesity and hypertension, prediabetes with normal weight and hypertension had the highest risk of MA (adjusted odds ratio, 6.39; 95% confidence interval, 2.90–14.10) compared to those with nonobese and normal blood pressure.CONCLUSIONS: Our findings suggest that nonobese prediabetes with hypertension would need to be more concerned about MA than do obese prediabetes with hypertension.
Albuminuria ; Blood Glucose ; Blood Pressure ; Body Mass Index ; Cardiovascular Diseases ; Diabetic Nephropathies ; Fasting ; Health Promotion ; Hypertension ; Logistic Models ; Mortality ; Obesity ; Odds Ratio ; Prediabetic State ; Prehypertension ; Retrospective Studies ; Weights and Measures

BACKGROUND: Heat tobacco products (HTPs) are emerging in Korea. There are few studies that investigated the rates of HTPs use among military personnel in Korea. This study was performed to identify the prevalence of HTPs experience and use. Also this study aimed to evaluate the related factors of HTPs experience and use among military personnel in Korea. METHODS: The study subjects were 3,878 military personnel participated health survey for Korean soldiers from November to December in 2018. Binominal logistic regression analysis was performed to confirm the related factors of HTPs experience and use among military personnel in Korea. RESULTS: The HTPs experience and current use rates of study subjects were 17.4% and 8.7%, respectively. And the HTPs experience and current use among military personnel was associated with college/university degree (adjusted odds ratio [aOR] 1.441, 1.377), lance-corporal (aOR 2.049, 5.636), superiors' smoking in military camp (aOR 1.516, 1.567), interest in health (aOR 1.637, 1.571), ever used smoking (aOR 2.817, 3.575), and ever used electronic cigarette (E-cigarette) (aOR 3.129, 1.587). CONCLUSIONS The HTPs experience and current use among military personnel are closely related to educational level, military level, smoking status of the superiors, interests in health, conventional cigarette smoking, and E-cigarette use.

BACKGROUND: Microalbuminuria (MA) is a predictor for diabetic nephropathy and mortality of cardiovascular disease. Diabetic nephropathy can be prevented by blood glucose and blood pressure control. Koreans have been found to have a significantly higher risk of type 2 diabetes than Caucasians, despite having normal weights. It is necessary to consider obesity status in the prevention of type 2 diabetes. This study aimed to determine the relationship between MA and hypertension according to obesity status in prediabetes. METHODS: This study was retrospectively conducted in 1,183 prediabetes, aged 30-70 years with fasting blood glucose levels of 100-125 mg/dL or hemoglobin A1c levels of 5.7–6.4% who health examinees at 16 health promotion centers from 2015 to 2016. Study subjects were classified according to obesity and hypertension. Obesity is defined as body mass index of ≥25 kg/m². Blood pressure was categorized as follows: normal blood pressure, <120/80 mmHg; prehypertension, 120–139/80–89 mmHg; and hypertension, ≥140/90 mmHg. We analyzed the relationship between MA and hypertension according to obesity using multivariable logistic regression analysis. RESULTS: While both prehypertensive and hypertensive subgroups were significantly associated with MA in the nonobese, the hypertensive subgroup was only associated with MA in the obese. In the combined effects of obesity and hypertension, prediabetes with normal weight and hypertension had the highest risk of MA (adjusted odds ratio, 6.39; 95% confidence interval, 2.90–14.10) compared to those with nonobese and normal blood pressure. CONCLUSIONS Our findings suggest that nonobese prediabetes with hypertension would need to be more concerned about MA than do obese prediabetes with hypertension.

Somatostatinoma is a rare form of neuroendocrine tumor that was first described in 1977. Most tumors have involved the pancreas, and gastrointestinal tract involvement is rare. Somatostatinomas of the ampulla of Vater are extremely rare and present distinct clinical and pathologic differences. Pancreatic somatostatinoma has been associated with a clinical syndrome of dyspepsia, mild diabetes, cholelithiasis, steatorrhea, and hypochlorhydria, but duodenal somatostatinoma, in general, has been clinically silent. A further contrast is that duodenal carcinoid tumors, mainly gastrinoma, tended to be benign, whereas ampullary carcinoid tumors, mainly somatostatinoma, exhibited malignant behavior. Therefore, definite diagnosis is important for treatment and prognosis, and is performed by image study, immunohistochemistry and electron microscopic examination. We report a case of somatostatinoma of the ampulla of Vater in a 51-year-old male. He complained of generalized abdominal pain for a few days. Gastrofiberscopically, a 1.2 cm sized bulging mass was observed on the ampulla of Vater. Radiologically, on abdomen CT, a protruding enhancing mass was revealed in the duodenum. In octreoscan, there was an abnormal focus off increased radiouptake in the infrahepatic area. He underwent a pancreatoduodenectomy. Grossly, the mass was an intraluminary protruding polypoid submucosal mass with focal ulceration in the ampulla of Vater. Histologically, it showed well-differentiated nonpleomorphic tubular cell nest and psammoma bodies. Immunohistochemically, the tumor cells showed a neuroendocrine nature with synaptophysin immunostain and intense staining only for somatostatin.
Abdomen ; Abdominal Pain ; Achlorhydria ; Ampulla of Vater* ; Carcinoid Tumor ; Cholelithiasis ; Diagnosis ; Duodenum ; Dyspepsia ; Gastrinoma ; Gastrointestinal Tract ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Neuroendocrine Tumors ; Pancreas ; Pancreaticoduodenectomy ; Prognosis ; Somatostatin ; Somatostatinoma* ; Steatorrhea ; Synaptophysin ; Ulcer

'Takotsubo cardiomyopathy' or 'stress-induced cardiomyopathy' is a newly described clinical entity characterized by transient left ventricular apical ballooning and left ventricular apical dyskinesis in the absence of angiographic feature of significant coronary artery disease. The cause of takotsubo cardiomyopathy is unclear, but catecholamines probably play a role in the takotsubo cardiomyopathy. We report a case of pheochromocytoma-induced takotsubo cardiomyopathy that showed atypical pattern of reversed takotsubo cardiomyopathy with transient significant mitral regurgitation. This is the first case showing the reversal of takotsubo cardiomyopathy due to pheochromocytoma in Korea.
Cardiomyopathies ; Catecholamines ; Coronary Artery Disease ; Humans ; Korea ; Mitral Valve Insufficiency ; Pheochromocytoma* ; Takotsubo Cardiomyopathy*

Pancreatic panniculitis is a rare complication characterized by subcutaneous fat necrosis associated with pancreatic disease. It has been postulated that pancreatic panniculitis is caused by the systemic activity of pancreatic enzymes that lead to microcirculatory disturbances. We report a 41-year-old heavy alcoholic woman with pancreatic panniculitis that coexisted with acute and chronic pancreatitis. She was diagnosed with chronic pancreatitis and alcoholic liver cirrhosis 5 years ago. She presented with multiple, tender, erythematous, subcutaneous nodules with heat sensation on both lower legs. Laboratory evaluation revealed an increase in the serum blood amylase and lipase. Histopathologic findings showed fat necrosis with inflammation around the necrotic subcutaneous fat tissue. The lesions subsided gradually with an improvement of acute pancreatitis.
Adult ; Alcoholics ; Amylases ; Fat Necrosis ; Female ; Hot Temperature ; Humans ; Inflammation ; Leg ; Lipase ; Liver Cirrhosis, Alcoholic ; Necrosis ; Pancreatic Diseases ; Pancreatitis ; Pancreatitis, Chronic* ; Panniculitis* ; Sensation ; Subcutaneous Fat