1.Chryseobacterium indologenes Isolated from Clinical Specimens.
Korean Journal of Clinical Microbiology 1999;2(1):101-104
Chryseobacterium indologenes is a nonfastidious, oxidase-positive, gram-negative rod that does not ferment glucose. It is known to be associated with a variety of clinical infections. We report six cases of C. indologenes isolated from clinical specimens, which were seen at our institution over a 2-year period. These organisms were recovered from blood, pleural fluid, peritoneal fluid, bile, endotracheal aspirate, and sputum. We described clinical characteristics, treatment outcome, microbiological characteristics, and in vitro antibiotic susceptibility test.
Ascitic Fluid
;
Bile
;
Chryseobacterium*
;
Glucose
;
Sputum
;
Treatment Outcome
2.A case of community-acquired pneumonia and sepsis caused by Chryseobacterium meningosepticum.
Sung Jun KIM ; Seung Min LEE ; So Yeon PARK ; Sung Ho RYU ; Yong Bum PARK ; Joong Sik EOM ; Jin Seo LEE
Korean Journal of Medicine 2010;79(4):453-456
Chryseobacterium meningosepticum is a ubiquitous Gram-negative rod widely distributed in natural and hospital environments. It mostly causes meningitis in premature and newborn infants. Few such cases have been reported in Korea, and no case of community-acquired pneumonia caused by Chryseobacterium meningosepticum. A 53-year-old man was brought to the emergency department because of severe pneumonia. We report a case of community-acquired pneumonia and sepsis caused by Chryseobacterium meningosepticum.
Chryseobacterium
;
Emergencies
;
Humans
;
Infant, Newborn
;
Korea
;
Meningitis
;
Middle Aged
;
Pneumonia
;
Sepsis
3.A case of peritoneal dialysis-associated peritonitis caused by Sphingomonas paucimobilis.
Jae Un LEE ; Joong Keun KIM ; So Hee YUN ; Moon Sik PARK ; Na Eun LEE ; In O SUN ; Kwang Young LEE
Kidney Research and Clinical Practice 2013;32(2):78-80
Sphingomonas paucimobilis is an aerobic Gram-negative bacillus found in soil and water. Knowledge regarding the role of this infectious agent is limited because it is rarely isolated from human material. Furthermore, it is an unusual pathogen in cases of peritoneal dialysis (PD)-associated peritonitis. The clinical courses and outcomes of peritonitis caused by S. paucimobilis are variable. Whereas some patients were cured with appropriate antibiotic therapy, others required catheter removal. Cases of PD-associated peritonitis caused by S. paucimobilis have been reported worldwide, and there was a case report of coinfection with S. paucimobilis and Chryseobacterium indologenes in Korea. However, there has been no case caused by S. paucimobilis as a single pathogen. We report a case of PD-associated peritonitis due to S. paucimobilis in which the patient recovered after catheter removal.
Bacillus
;
Catheters
;
Chryseobacterium
;
Coinfection
;
Humans
;
Korea
;
Peritoneal Dialysis
;
Peritonitis
;
Soil
;
Sphingomonas
4.Peritoneal Dialysis-associated Peritonitis Caused by Chryseobacterium indologenes
Myung Woo CHOI ; Sung Sik OH ; Mi Rim CHOI ; Jong Hwa LEE ; Hyun Ju YANG ; In O SUN ; Kwang Young LEE
Korean Journal of Medicine 2018;93(1):65-67
Chryseobacterium indologenes (C. indologenes) is a nonmotile, gram-negative bacillus that is widely distributed in nature. Generally considered nonpathogenic, C. indologenes rarely infects humans and is not normally present in the human microflora. C. indologenes infections have been observed in cases of peritoneal dialysis (PD)-associated peritonitis, although the incidence of these infections is low. Although C. indologenes is generally susceptible to trimethoprim-sulfamethoxazole, levofloxacin, ciprofloxacin, piperacillin-tazobactam, and cefepime, no guidelines have been established for the treatment of PD-associated peritonitis. Here we report the first case of PD-associated peritonitis in Korea with C. indologenes identified as the sole etiologic agent. The patient recovered after intraperitoneal antibiotic treatment without the need for Tenckhoff catheter removal.
Bacillus
;
Catheters
;
Chryseobacterium
;
Ciprofloxacin
;
Humans
;
Incidence
;
Korea
;
Levofloxacin
;
Peritoneal Dialysis
;
Peritonitis
;
Trimethoprim, Sulfamethoxazole Drug Combination
5.Keratitis with Elizabethkingia meningoseptica Occurring after Contact Lens Wear: A Case Report.
Young Seong YANG ; Ji Woong CHUN ; Jae Woong KOH
Korean Journal of Ophthalmology 2013;27(2):133-136
To report keratitis with Elizabethkingia meningoseptica, which occurred in a healthy patient after wearing contact lenses for 6 months. A 24-year-old male patient visited our hospital with ocular pain. This patient had a history of wearing soft contact lenses for 6 months, about 10 hours per day. At initial presentation, slit lamp examination showed corneal stromal infiltrations and small epithelial defect. Microbiological examinations were performed from corneal scrapings, contact lenses, and the contact lens case and solution. The culture results from contact lenses, contact lens case and solution were all positive for Elizabethkingia meningoseptica. Thus, we could confirm that the direct cause of keratitis was contamination of the contact lenses. The patient was treated with 0.3% gatifloxacin. After treatment, the corneal epithelial defect was completely healed, and a slight residual subepithelial corneal opacity was observed. We diagnosed keratitis with Elizabethkingia meningoseptica in a healthy young male wearing soft contact lenses. We conclude that Elizabethkingia meningoseptica should be considered as a rare but potential pathogen for lens-related keratitis in a healthy host.
*Chryseobacterium
;
Contact Lenses, Hydrophilic/*adverse effects/*microbiology
;
Flavobacteriaceae Infections/*complications
;
Humans
;
Keratitis/*etiology/*microbiology
;
Male
;
Young Adult
6.Keratitis with Elizabethkingia meningoseptica Occurring after Contact Lens Wear: A Case Report.
Young Seong YANG ; Ji Woong CHUN ; Jae Woong KOH
Korean Journal of Ophthalmology 2013;27(2):133-136
To report keratitis with Elizabethkingia meningoseptica, which occurred in a healthy patient after wearing contact lenses for 6 months. A 24-year-old male patient visited our hospital with ocular pain. This patient had a history of wearing soft contact lenses for 6 months, about 10 hours per day. At initial presentation, slit lamp examination showed corneal stromal infiltrations and small epithelial defect. Microbiological examinations were performed from corneal scrapings, contact lenses, and the contact lens case and solution. The culture results from contact lenses, contact lens case and solution were all positive for Elizabethkingia meningoseptica. Thus, we could confirm that the direct cause of keratitis was contamination of the contact lenses. The patient was treated with 0.3% gatifloxacin. After treatment, the corneal epithelial defect was completely healed, and a slight residual subepithelial corneal opacity was observed. We diagnosed keratitis with Elizabethkingia meningoseptica in a healthy young male wearing soft contact lenses. We conclude that Elizabethkingia meningoseptica should be considered as a rare but potential pathogen for lens-related keratitis in a healthy host.
*Chryseobacterium
;
Contact Lenses, Hydrophilic/*adverse effects/*microbiology
;
Flavobacteriaceae Infections/*complications
;
Humans
;
Keratitis/*etiology/*microbiology
;
Male
;
Young Adult
7.A Case of Chryseobacterium (Flavobacterium) meningosepticum Peritonitis in a Patient on CAPD.
Young Sook LEE ; You Hyun LEE ; Seong Nam KIM ; Duk Hee KANG ; Kyu Bok CHOI ; Kyun Il YOON ; Hee Won MOON ; Mi Ae LEE
Korean Journal of Nephrology 2002;21(5):815-819
Peritonitis remains the leading cause of morbidity and technique failure for patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Chryseobacterium meningosepticum is the most common pathogen for humans among Chryseobacterium species and a few cases of CAPD peritonitis caused by C. meningosepticum were reported in the world. We experienced a case of CAPD peritonitis by C. meningosepticum in Ewha Womans University Hospital, Seoul, Korea. A 52-year-old diabetic woman on CAPD was admitted with turbid peritoneal fluid. She was suffered from three episodes of peritonitis. Effluent was cloudy with a cell count of 1,620 WBC/ mm3 (94% neutrophils, 4% lymphocytes). Effluent cultures obtained on 6th hospital day revealed a mixed growth of C. meningosepticum and P. aeruginosa. Tenckhoff catheter was removed due to persistent cloudy effluent till 9th hospital day. We herein report a case of peritonitis caused by C. meningosepticum and review the literature of similar cases of peritonitis.
Ascitic Fluid
;
Catheters
;
Cell Count
;
Chryseobacterium*
;
Female
;
Humans
;
Korea
;
Middle Aged
;
Neutrophils
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis*
;
Seoul
8.A Case of Peritonitis caused by Chryseobacterium meningosepticum in a Patient Treated with Peritoneal Dialysis.
Hyang Mo KOO ; Fa mee DOH ; Eun Jin KIM ; Ea Wha KANG ; Suk Kyun SHIN ; Tae Ik CHANG
Korean Journal of Nephrology 2011;30(3):339-342
Chryseobacterium meningosepticum is rarely encountered as a pathogen causing peritonitis in peritoneal dialysis (PD) patients. We report a case of peritonitis due to Chryseobacterium meningosepticum, which was treated successfully with intraperitoneal (IP) vancomycin and ciprofloxacin, and without PD catheter removal. Peritonitis was developed in a 53-year-old PD patient on the third hospital day. Although empirical IP treatment with cefazolin and tobramycin was initiated and maintained for 3 days, the fever and signs of peritonitis persisted. Antibiotics were changed to cefoperazone/sulbactam, amikacin, and vancomycin due to clinical deterioration. After 3 days of vancomycin use, leukocyte count in PD fluid was less than 100/mm3 and the patient became asymptomatic. On seventh day after the onset of peritonitis, Chryseobacterium meningosepticum was isolated from initial dialysate sample, and this strain was susceptible to ciprofloxacin, piperacillin, and piperacillin/tazobactam. Accordingly, we changed the antibiotics to ciprofloxacin and vancomycin, which were given for the total of 14 days. Even though Chryseobacterium meningosepticum is an uncommon causative organism of peritonitis in PD patients, this report suggests that vancomycin and ciprofloxacin are effective as empiric therapy, and early suspicion and appropriate antimicrobial therapy are crucial to the successful treatment of peritonitis due to Chryseobacterium meningosepticum without catheter removal.
Amikacin
;
Anti-Bacterial Agents
;
Catheters
;
Cefazolin
;
Chryseobacterium
;
Ciprofloxacin
;
Fever
;
Humans
;
Leukocyte Count
;
Middle Aged
;
Peritoneal Dialysis
;
Peritonitis
;
Piperacillin
;
Sprains and Strains
;
Tobramycin
;
Vancomycin
9.Two cases of Chryseobacterium meningosepticum infection in a neonatal intensive care unit.
Korean Journal of Pediatrics 2007;50(7):698-701
We report on two premature infants who developed nosocomial infection caused by Chryseobacterium meningosepticum in a neonatal intensive care unit (NICU). One premature infant developed sepsis, meningitis, and hydrocephalus, and was treated successfully with ciprofloxacin plus trimethoprim-sulfamethoxazole combination therapy for 4 weeks and with a ventriculoperitoneal shunt. The other premature infant, who was in a chronically debilitated state, had infection that had colonized only in the respiratory tract but had no clinical signs for 66 days. Extensive environmental surveillance demonstrated that the suction bottle apparatus was the source of infection. We prevented the spread of infection by closing the NICU temporarily, isolating the patients early in their infection, and eradicating the source of infection source.
Chryseobacterium*
;
Ciprofloxacin
;
Colon
;
Cross Infection
;
Environmental Monitoring
;
Humans
;
Hydrocephalus
;
Infant, Newborn
;
Infant, Premature
;
Intensive Care, Neonatal*
;
Meningitis
;
Respiratory System
;
Sepsis
;
Suction
;
Trimethoprim, Sulfamethoxazole Drug Combination
;
Ventriculoperitoneal Shunt
10.Peritonitis by Chryseobacterium indologenes and Sphingomonas paucimobilis in a Patient Undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD).
Jeong Soo YOON ; Eun Ah HWANG ; Mi Hyun CHANG ; Woo Young PARK ; Kyu Bok JIN ; Seung Yeup HAN ; Sung Bae PARK ; Hyun Chul KIM ; Nam Hee RYOO
Korean Journal of Nephrology 2007;26(6):801-805
Bacterial peritonitis is a well-recognized complication of continuous ambulatory peritoneal dialysis (CAPD) in patients with end-stage renal failure. Chryseobacterium indologenes is a non-fermentative Gram-negative bacillus that is a rare pathogen in humans and Sphinomomas paucimobilis has rarely been reported as an opportunistic human pathogen. We present a case of peritonitis due to unusual pathogens, C. indologenes and S. paucimobilis, unresponsive to the standard antibiotics therapy. A 51-year-old diabetic man undergoing CAPD for 45 days developed the first peritonitis due to C. indolegenes. Although he had received intraperitoneal antibiotics with good in vitro activity against organism, the signs of peritonitis persisted. S. paucimobilis was isolated from dialysate sample. The Tenckhoff catheter was finally removed on 19th day of hospitalization and the fever and abdominal pain subsided.
Abdominal Pain
;
Anti-Bacterial Agents
;
Bacillus
;
Catheters
;
Chryseobacterium*
;
Fever
;
Hospitalization
;
Humans
;
Kidney Failure, Chronic
;
Middle Aged
;
Peritoneal Dialysis
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Peritonitis*
;
Sphingomonas*