No abstract available.
Chromoblastomycosis* ; Japan*

Chromoblastomycosis is an endemic mycoses which has been misdiagnosed or underdiagnosed in the past. This may be due to the clinicopathologic characteristics that it shares with other neglected tropical diseases such as leprosy and cutaneous tuberculosis. Correlating clinical findings with histopathologic cues will lead clinicians to correct diagnosis and subsequent treatment success.
Chromoblastomycosis ; Invasive Fungal Infections ; Itraconazole

Chromoblastomycosis, a chronic fungal infection of the skin and subcutaneous tissue, is known to be difficult to treat. Recently itraconazole has proved effective for treatment of this infection, but requires a prolonged treatment course. We experienced a case of chromoblastomycosis caused by Fonsecaea pedrosoi in a 68-year-old Korean man showing a complete resolution with a short course of oral itraconazole, 200 mg daily, for six weeks.
Aged ; Chromoblastomycosis* ; Humans ; Itraconazole* ; Skin ; Subcutaneous Tissue

Phaeohyphomycosis is a subcutaneous and systemic infection caused by dark-walled hyphae and differs from chromoblastomycosis in that it has no sclerotic cells. It commonly occurs in a immunosuppressed host. Exophiala dermatitidis, common pathogen of phaeohyphomycosis, has been commonly reported in Japan, but very rare in Korea. This report describes a case of phaeohyphomycosis due to Exophiala dermatitidis successfully treated with itraconazole.
Chromoblastomycosis ; Exophiala* ; Hyphae ; Immunocompromised Host ; Itraconazole* ; Japan ; Korea ; Phaeohyphomycosis*

The reports on the subcutaneous infection cases by the opportunistic fungi, reported in Korean Journal of Dermatology, Annals of Dermatology and Korean Journal of Medical Mycology from 1960 to 1999, were summarized. The opportunistic subcutaneous fungal diseases were cryptococcosis, aspergillosis, mucormycosis, pheohypomycosis, pseudallescheriasis, chromomycosis, paecilomycosis, fusariosis, sporotrichosis. Only two cases were the systemic infection with cutaneous manifestations and the others were the primary cutaneous infection. Besides sporotrichosis, all the fungal diseases began to be reported since 1980's. The total number of the cases was insidiously increased.
Aspergillosis ; Chromoblastomycosis ; Cryptococcosis ; Dermatology ; Fungi ; Fusariosis ; Mucormycosis ; Mycology ; Sporotrichosis

Medical mycology has gone through five distinct eras: 1) Fungi causing dermatophytoses, 2) Discovery of rare and fatal systemic mycoses, 3) Realization that fungi cause common and subclinical diseases, 4) AIDS and the era of the compromised host, 5) Broad-spectrum antifungals with few side effects. Chromoblastomycosis caused by a group of dematiaceous fungi is a common disease in china. To date almost 500 cases have been repoted. This article aims to introduce epidemiology, microbiology, clinical features, laboratory diagnosis and treatment of chromoblastomycosis in china.
China ; Chromoblastomycosis ; Clinical Laboratory Techniques ; Fungi ; Mycology ; Mycoses ; Tinea

In recent years, there has been a rapid decrease in amphibian populations worldwide, and infectious diseases have been associated with this decline. Diseased frogs inhabiting Korea were collected from fields, and the diseases were identified by morphological and molecular analyses. Two fungal diseases-saprolegniasis and chromomycosis-were detected in the frogs. Saprolegniasis caused by Saprolegnia spp. was found in Rana plancyi chosenica from Gangwon-do and Rana huanrenensis from Chungbuk. Chromomycosis, which is caused by infection with Cladosporium cladosporioides, was detected in Rana catesbeiana from Busan.
Amphibians ; Chromoblastomycosis ; Cladosporium ; Communicable Diseases ; Korea ; Rana catesbeiana ; Ranidae ; Saprolegnia

Chromoblastomycosis is a chronic fungal disease of the skin and subcutaneous tissues caused by a group of dematiaceous (black) fungi. The most common etiologic agents are Fonsecaea pedrosoi and Cladophialophora carrionii, both of which can be isolated from plant debris. The infection usually follows traumatic inoculation by a penetrating thorn or splinter wound. Several months after the injury, painless papules or nodules appear on the affected area; these papules then progress to scaly and verrucose plaques. We report a case of chromoblastomycosis caused by Phialophora richardsiae, which has been rarely associated with chromoblastomycosis. The case involved a 43-year-old male, who for the past 2 months had noted an erythematous, pustulous plaque that was somewhat dark brown in color on his right shin; the plaque also had intermittent purulent discharge and crust formation. On histopathological examination, chronic granulomatous inflammation and sclerotic cells were seen. The tissue fungus culture grew out the typical black fungi of P. richardsiae, which was confirmed by polymerase chain reaction. The patient has been treated with a combination of terbinafine and itraconazole for 3 months with a good clinical response.
Adult ; Chromoblastomycosis ; Fungi ; Humans ; Inflammation ; Itraconazole ; Male ; Naphthalenes ; Phialophora ; Plants ; Polymerase Chain Reaction ; Skin ; Subcutaneous Tissue

Chromomycosis is a chronic mycosis of the skin and subcutaneous tissue characterized by a brown, thick-walled, round, nonbudding form of causative fungi in the tissue. We report a case of chromomycosis caused by Fonsecaea pedrosoi in a 56-year-old Korean woman who showed 3 x 4cm sized deep ulcerations on the dorsa of both hands. Histopathologically, chronic granulomatous inflammation and sclerotic cells were observed. Fonsecaea pedrosoi was grown into typical black colonies in fungus culture. She was treated with pedicle flap graft followed by oral itraconazole, and showed clinical improvement.
Chromoblastomycosis* ; Female ; Fungi ; Hand* ; Humans ; Inflammation ; Itraconazole ; Middle Aged ; Skin ; Subcutaneous Tissue ; Transplants ; Ulcer*

The dematiaceous fungi, characterized by having melanin in their cell walls, have become significant due to an increasing cause of human skin disease in Korea. The disease caused by dematiaceous fungi contain pityriasis (tinea) nigra, onychomycosis (in part), black piedra, keratomycosis (in part), chromoblastomycosis, phaeohyphomycosis, and eumycotic mycetoma (in part). Chromoblastomycosis is subcutaneous mycotic disease that contain sclerotic cells and histologically show pseudoepitheliomatous hyperplasia with microabscess, and phaeohyphomycosis is a group of mycotic infections that contain dematiaceous yeast-like cells, pseudohypae-like elements, hyphae or combination of these form in tissue.
Cell Wall ; Chromoblastomycosis ; Fungi* ; Humans ; Hyperplasia ; Hyphae ; Korea ; Melanins ; Mycetoma ; Onychomycosis ; Phaeohyphomycosis ; Piedra ; Pityriasis ; Skin Diseases