Pheochromocytoma is one of the surgically curable hypertensive diseases and can arise wherever chromaffin cells are located. Herein, a case of extra-adrenal pheochromocytoma developed in a 51 year-old male is presented with brief review of literatures.
Chromaffin Cells ; Humans ; Male ; Middle Aged ; Pheochromocytoma*

Pheochromocytoma is one of the surgically curable hypertensive syndrome and may arise wherever chromaffin cells are located. A case of a left large adrenal pheochromocytoma developed in a 49 year old male is presented with brief review of literatures.
Chromaffin Cells ; Humans ; Male ; Middle Aged ; Pheochromocytoma*

Pheochromocytoma stems from the chromaffin cell and mostly is located in the adrenal medulla. It is an important cause of secondary hypertension due to correction of hypertension by a resection of the tumor. Because it produces and secretes catecholamine, it bothers anesthesiologists with excessive hypertension, tachycardia and arrhythmia during the anesthetic period. Therefore, anesthetic management is directed to avoid these conditions. We report a case of bilateral pheochromocytoma successfully managed intraoperatively with an infusion of nicardipine and an intermittent esmolol injection.
Adrenal Medulla ; Arrhythmias, Cardiac ; Chromaffin Cells ; Hypertension ; Nicardipine* ; Pheochromocytoma* ; Tachycardia

Pheochromcytomas are comparatively rare and arise wherever chromaffin cells are located Approximately 10-15% have been found outside the adrenal gland. A case of extra-adrenal pheochromocytoma which occurred in a 38-year-old woman is presented with review of the literature.
Adrenal Glands ; Adult ; Chromaffin Cells ; Female ; Humans ; Pheochromocytoma*

Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas. However, cases of middle mediastinal paragangliomas are very rare. In this case, the patient presented with a voice change and a headache. A middle mediastinal soft tissue mass with marked enhancement was detected on computed tomography of the chest. The 24-hour urine catecholamine level was markedly elevated. The middle mediastinal mass was biopsied via mediastinoscopy and the resulting immunohistochemical staining was compatible with a diagnosis of middle mediastinal paraganglioma. The mass was resected surgically and the symptoms were relieved.
Adrenal Medulla ; Chromaffin Cells ; Headache ; Humans ; Mediastinoscopy ; Mediastinum ; Neuroendocrine Tumors ; Paraganglioma ; Pheochromocytoma ; Thorax ; Voice

Pheochromocytoma is derived from the chromaffin cells and patients with pheochromocytoma present with several signs and symptoms by producing, storing and secreting catecholamine. Spontaneous rupture or necrosis of pheochromocytoma is extremely rare, but it can be lethal because of the dramatic change in the circulation such as an acute abdominal emergency or shock. Spontaneous remission of the clinical symptoms due to necrosis of the pheochromocytoma is rare. We describe such a case that presented with cardiogenic shock due to extensive necrosis of the pheochromocytoma and this was followed by spontaneous remission of the clinical symptoms without removal of the pheochromocytoma.
Chromaffin Cells ; Emergencies ; Humans ; Necrosis ; Pheochromocytoma ; Remission, Spontaneous ; Rupture, Spontaneous ; Shock ; Shock, Cardiogenic

Pheochromocytomas can arise wherever chromaffin cells are found, and most of them(90%) are in one or both adrenal glands. But they may be located anywhere along the sympathetic chain and rarely in aberrant sites. One of the common extra-adrenal sites from which these tumors can arise is a collection of para-aortic and para-ganglion cells around the origin of the inferior mesenteric artery. We experienced a case of extra-adrenal pheochromocytoma located at the organ of Zukerkandl in a 21-year-old female patient with abdominal colic and paroxysmal hypertension, whose symptoms and blood pressure returned to normal after successful surgical excision of the tumor.
Adrenal Glands ; Blood Pressure ; Chromaffin Cells ; Colic* ; Female ; Humans ; Hypertension* ; Mesenteric Artery, Inferior ; Pheochromocytoma* ; Young Adult

Pheochromocytoma originate from chromaffin cells and occur in the adrenal medulla in majority. About 10 per cent of pheochromocytomas can occur in the ectopic or extra-adrenal sites, anywhere along the fetal route of the chromaffin tissues. Pheochromocytoma of the bladder is a rare neoplasm that often occurs with the unique symptom complex of micturitional attacks, such as headache, palpitation, hypertension of sweating due to increased catecholamine secretion during detrusor activity. We report a very rare case of nonfunctioning pheochromocytoma of the bladder in a 67- year-old woman without typical symptoms. Preoperatively elevated urine catecholamines and their metabolites returned to normal after removal of the tumor.
Adrenal Medulla ; Catecholamines ; Chromaffin Cells ; Female ; Headache ; Humans ; Hypertension ; Pheochromocytoma* ; Sweat ; Sweating ; Urinary Bladder*

A pheochromocytoma is a neuroectodermal tumor that originates from the chromaffin cells of the sympathetic system. It has typical symptoms or signs, such as periodic attacks of paroxysmal hypertension, palpitation, headache, and sweating, related to an increased catecholamine secretion. Types of catecholamine secreted from tumors are usually norepinephrine and epinerphrine. There are a few reports of dopamine-secreting pheochromocytoma with absence of other catecholamines secretion. Here, we report the case of a 59-year-old man with dopamine-secreting pheochromocytoma, with no typical symptoms or signs.
Catecholamines ; Chromaffin Cells ; Dopamine ; Headache ; Humans ; Hypertension ; Middle Aged ; Neuroectodermal Tumors ; Norepinephrine ; Pheochromocytoma ; Sweat ; Sweating

Paragangliomas of the urinary bladder are very rare tumors of the paraganglion system that arise from chromaffin cells in or near the sympathetic ganglia. Only approximately 15% of them develop from extra-adrenal chromaffin tissue. Most of these tumors are hormonally active and secrete mainly noradrenaline (rarely adrenaline), calcitonin, and adrenocorticotropic hormone. Paragangliomas are generally benign tumors, with less than 10% being malignant. Here we report a case of a paraganglioma arising in a urinary bladder with a bladder stone.
Adrenocorticotropic Hormone ; Calcitonin ; Chromaffin Cells ; Ganglia, Sympathetic ; Norepinephrine ; Paraganglioma ; Urinary Bladder ; Urinary Bladder Calculi