PURPOSE: To report a case of choroidal neovascularization (CNV) secondary to candida chorioretinitis initially treated with an intravitreal bevacizumab injection. CASE SUMMARY: A 50-year-old female presented at our clinic with decreased vision and metamorphopsia in her left eye of 5 days duration. She received an anti-fungal treatment 2 months prior due to the presence of endogenous candida choroiditis in both eyes. Fluorescein angiography and optical coherence tomography (OCT) revealed juxtafoveal CNV in her left eye. Three monthly intravitreal injections of bevacizumab were administered as the initial loading dosage. Her visual symptoms improved and CNV regression was observed on OCT. No recurrence or complications were observed during the 6 month follow-up. CONCLUSIONS: Based on the present study results we suggest that intravitreal bevacizumab injection can be used to effectively treat CNV and improve visual symptoms during the treatment of juxtafoveal CNV associated with candida choroiditis.
Candida* ; Chorioretinitis* ; Choroid ; Choroidal Neovascularization* ; Choroiditis ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Intravitreal Injections ; Middle Aged ; Recurrence ; Tomography, Optical Coherence ; Vision Disorders ; Bevacizumab

Serpiginous choroiditis is a chronic. progressive, recurrent, and usually bilateral disease involving the choriocapillaris, retinal pigment epithelium, and retina. This disease classically involves the juxtapapillary retina and extends outward in a pseudopodial fashion. We report a case of serpiginous choroiditis beginning in the posterior pole without initial peripapillary lesion, and extending toward the optic disc. The fluorescein angiogram of the lesion showed hypofluorescence in the early phase and hyperfluorescence in the late phase, and the progression of the lesion with time.
Choroid* ; Choroiditis* ; Fluorescein ; Retina ; Retinal Pigment Epithelium

This disease entity, first described under the desgnation of cyclitis by Ernst Fuchs, has received renewed attention in the recenet years, having been described as peripheral uveitis, pars planitis, and cyclitis with peripheral chorioretinitis. Apparently new ophthalmoscopic findings have caused some obserbers to believe they are dealing with a new entity, because indirect ophthalmoscopy with scleral depression shows exudation in the pars plana region in severe or advanced cases. In this entity, The following characteristic findings are noted, occurring bilaterally, inflammatory cells in anterior vitreous, slight flare and cells in the anterior chamber in come instances, dilated veins, and snowball deposition of inflammatory cells over the pare plana and ora serrata, seen with scleral depression and indirect ophthalmoscope extending over the lower 180 degrees. Cystoid macular degeneration are demonstrated with fluorescein angiography in over half the caces; papilledema may occur in late cases; and peripheral retinal perivascular sheathing is noted in long standing cases.
Anterior Chamber ; Chorioretinitis ; Depression ; Fluorescein Angiography ; Macular Degeneration ; Ophthalmoscopes ; Ophthalmoscopy ; Papilledema ; Pars Planitis* ; Retinaldehyde ; Uveitis ; Veins

Zusammenfassung: In der vorliegenden Arbeit wurcle die heutige Kenntnis uber Symptome und Diagnose der Cy clitis anularis exsudativa pseudotumorosa aus dem Literaturuberblick und aufgrund von 2 eigenen FalIen kritisch zusammengefasst. Bestehen einer Aderhautbuckel in der Fudusperipherie, die gute Durchleuchtbarkeit der Votwolbung, ein positives Hagensches Zeichen und entzundliche Erscheinungen des Augapfels sprechen fur das Vorliegen einer Cyclitis anularis exsudativa pseudotumorosa. In manchen Fallen kann die Diagnose erst durch eine Probepunktion oder eine probatorische The Die mit Corticosteroid innerlich ex juvantivus gesichert werden. Die Cyclitis anularis exsudativa pseudotumorosa tritt oftim Kaufe einer rezidivierenden granulomatosen Entzundung des Bulbus auf. An sie schliessen sich haufig eine exudative Netzhautabhebung, eine Chorioretinitis, Netzhautblutungen, eine Sehnerventzundung, ein Maculaodem, eine Perivasculitis und Funktionsstorungen als deren Foige an. Viele Autoren fanden eine erniedrigte Tension bei bestehenden Aderhautabhebungen. Ais Folgeerscheinungen cler Cyclitis anularis exsudativa pseudotumorosa wurden auch eine Abflachung der Vorderkammer, eine vorubergehende Augeninnendruckerhohung im Hohepunkt der Krenkheit beobachtet. Die Cyclitis anularis anularis exsudativa pseudotumorosa im Gefolge der akuten Hypotonie tritt mit einer Vertiefung der Vorderkammer und einer Hypotonie des Bulbus auf. Es handelt sich hierbei um inkonstante Begleitssymptome. Man beobachtet eine Normalizierung der Vorderkammertiefe und des Augeninnendrcks zusammen mit dem Abklingen der abgehobenen Aderhaut. Nach Abheilung der Krankheit treten oft oraparalleler igmentstreifen und Funktionssiorungen im Gefolge von einer Retiopathie und einer Opticusatrophie auf. Die von Garmiger et al prazisierte Cyclitis anularis exsudativa pseudotumorosa durfte der von Rohrschneider angegebenen komplizierten spontanen serosen vorderen Aderhautabhebung gleich sein. Aus 2 eigenen Fallen und dem Literaturuberblick wird geschlossen, dass es sich bei der Cyclitis anularis exsudativa pseudotumorosa nicht um eine Erkrankung eigner Art, sondern um eine Begleitssymptome lasst vermuten, dass etwas anders als Cyslitis anularis exsudativa pseudotumorosa vorliegt.
Chorioretinitis

During the last few years, of the 19 patients required surgical treatment for retinal detachment, 9 patients were received combined treatment of diathermy in central teared zone and cryothermy in peripheral detached area, and another 10 patients were received separately by electric diathermy (4) and by cryothermy (6) with good reattachment of 16 patients (84.2%). Combined technique of diathermy and cryothermy has a benefit by the production of strong choroiditis in detached main area resulted from diathermy and of least inflammation scars in peripheral detached zone from cryothermy. And any significant postoperative complication was not found in all cases.
Choroid ; Choroiditis ; Cicatrix ; Diathermy* ; Humans ; Inflammation ; Postoperative Complications ; Retinal Detachment* ; Retinaldehyde*

Multifocal choroiditis and panuveitis(MCP) is a clinical syndrome characterized by vitritis, and punched-out fundus lesions mimicking presumed ocular histoplasmosis. We diagnosed MCP in a twenty-eight years old woman with the complaint of decreased vision and floater symptom. Retinochoroidal anastomosis via one of retinochoroidal scars was noted in this case. The patient was treated with oral and periocular steroid and ws observed for 11 months during which choroidal neovascularization and macular edema ws not developed. We present this case because, as far as our knowledge goes, There has been no reported case of MCP with retinochoroidal anastomosis.
Choroid* ; Choroidal Neovascularization ; Choroiditis* ; Cicatrix ; Female ; Histoplasmosis ; Humans ; Macular Edema ; Panuveitis*

We conducted a retrospective analysis of 394 patients with uveitis seen at Kyung Hee University Medical Center from January 1982 to June 1987 to determine the frequency of occurence and to study the clinical characteristiscs of various form of uveitis. The results were as follows; 1. In classification of uveitis by location, 309 patients(78.4%) were anterior uveitis, 41 patients(10.4%) were posterior uveitis, 31 cases(7.9%) occurred as panuveitis. Pars planitis accounted for 13 cases(3.3%). Anterior uveitis was the most common causes of uveitis. 2. In cases of anterior uveitis, 127 cases(32.7%) were idiopathic iridocyclitis, 121 cases(30.7%) were traumatic iridocyclitis. In cases of posterior uveitis, Tuberculous uveitis was seen in 11 cases(2.8%), and Toxoplasmic chorioretinitis occured 10 cases(2.5%). In case of panuveitis, Behcet's disease was observed 10 patients(2.5%), and was the most common cause of panuveitis, pars planitis accounted for 13 cases(13.3%). 3. In aspect of age of uveitis, the peak age was 16~45 yrs.(60.6%). In case of anterior uveitis and pars planitis, peak age group was 16~45 yrs. In case of posterior uveitis and panuveitis, peak age group was 31~60 yrs. 4. In clinical characteristics of uveitis by location, anterior uveitis occurred at mostly younger age than did any uveitis(27.8 yrs.) in average age of diagnosis. In sex ratio, male patient of pars planitis predominated with over 3 times number of female patient. In the average duration of illness from the date of first symptom to date of first recorded quiescence, anterior uveitis was mostly shorter duration than did any uveitis(1.1 Mon.). 5. In the evaluation of laterality, all cases showed binocular equal distribution except pars planitis. 6. The largest number of complication was showed in panuveitis. 7. The most common symptom of uveitis was visual disturbance.
Academic Medical Centers ; Chorioretinitis ; Classification* ; Diagnosis ; Female ; Humans ; Iridocyclitis ; Male ; Panuveitis ; Pars Planitis ; Retrospective Studies ; Sex Ratio ; Telescopes ; Uveitis* ; Uveitis, Anterior ; Uveitis, Posterior

PURPOSE: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with widespread manifestations that rarely include the eye. We present a case of SLE-associated choroidoretinopathy and secondary angle closure attack in both eyes. CASE SUMMARY: A 58-year-old male was admitted into the urologic department complaining of right scrotal swelling, and then consulted with the ophthalmology department regarding both ocular pain and eye injection. The patient was diagnosed with acute angle closure attack using a slit lamp test and tonometry secondary to choroidoretinitis with choroidal detachment at fundus examination in both eyes. The rheumatologist performed systemic evaluation, including serologic tests, and then diagnosed the patient with SLE. After systemic steroid therapy, intraocular pressure was decreased and choroidal detachment disappeared with improvements of choroidoretinitis in both eyes. CONCLUSIONS: Patients with systemic lupus erythematosus choroidopathy can develop secondary angle closure attack, which can be effectively treated using systemic steroid therapy and antiglaucoma drugs.
Choroid ; Choroiditis ; Humans ; Intraocular Pressure ; Lupus Erythematosus, Systemic* ; Male ; Manometry ; Middle Aged ; Ophthalmology ; Serologic Tests ; Slit Lamp

PURPOSE: To characterize the clinical presentation and visual prognosis of punctate inner choroidopathy in Korean patients. METHODS: Eleven patients (seventeen eyes) with punctate inner choroidopathy (PIC) and four (six eyes) with multifocal choroiditis with panuveitis (MCP) were analyzed retrospectively. RESULTS: The mean age of the PIC patients was 32.2 +/- 9.3 years and the mean refractive error was -4.79 +/- 3.18 diopters. In all PIC eyes, fundus photographs showed multiple yellowish white punctate lesions and punched-out scars at the level of the inner retina and choroid. There was no significant difference between the mean initial visual acuity (0.67 +/- 0.40) and the mean final visual acuity (0.56 +/- 0.41). The major cause of visual deterioration was choroidal neovascularization (CNV) which developed in 4 eyes. In PIC, the lesions were located in the more posterior retina and the incidence of CNV was higher than in MCP. CONCLUSIONS: PIC affects young women with moderate myopia and shows the characteristic chorioretinal lesion. Although the eye with PIC usually maintains stable vision after initial attack, CNV may cause complications and significant visual loss.
Choroid ; Choroidal Neovascularization ; Choroiditis ; Cicatrix ; Female ; Humans ; Incidence ; Korea* ; Myopia ; Panuveitis ; Prognosis ; Refractive Errors ; Retina ; Retrospective Studies ; Visual Acuity

INTRODUCTIONTo review the long-term outcome of photodynamic therapy (PDT) with verteporfin for inflammatory chorioretinal disease with subfoveal choroidal neovascularisation (CNV) over a 1-year period.

MATERIALS AND METHODSRetrospective review of eyes with subfoveal CNV for associated choroiditis that were treated with PDT using verteporfin over a 1-year period.

MAIN OUTCOME MEASUREvisual acuity.

RESULTSFive eyes in 4 patients, with diagnoses including serpiginous choroiditis (2), ocular histoplasmosis syndrome (OHS, 1), and punctate inner choroidopathy (PIC, 2) underwent standard treatment procedure for PDT with verteporfin. Visual acuity, fluorescein angiography and treatment parameters were reviewed. Follow-up ranged from 12 months to 36 months (median, 36 months). Pre-PDT visual acuities ranged from 20/60 to 20/400 (median, 20/200). Post-PDT visual acuities ranged from 20/30 to 20/400 at 1 year (median, 20/300). Visual acuity was stabilised (within 1 line) or improved (greater than 1 line) in 3 eyes at 1 year and 4 of the 5 eyes at last follow-up.

CONCLUSIONPDT for subfoveal CNV may stabilise, but rarely improves, visual acuity in eyes with choroidal neovascularisation secondary to inflammatory chorioretinal disease.

Adult ; Aged ; Choroidal Neovascularization ; drug therapy ; etiology ; Choroiditis ; complications ; Female ; Humans ; Male ; Photochemotherapy ; Photosensitizing Agents ; therapeutic use ; Porphyrins ; therapeutic use