Serpiginous choroiditis is a chronic. progressive, recurrent, and usually bilateral disease involving the choriocapillaris, retinal pigment epithelium, and retina. This disease classically involves the juxtapapillary retina and extends outward in a pseudopodial fashion. We report a case of serpiginous choroiditis beginning in the posterior pole without initial peripapillary lesion, and extending toward the optic disc. The fluorescein angiogram of the lesion showed hypofluorescence in the early phase and hyperfluorescence in the late phase, and the progression of the lesion with time.
Choroid* ; Choroiditis* ; Fluorescein ; Retina ; Retinal Pigment Epithelium

During the last few years, of the 19 patients required surgical treatment for retinal detachment, 9 patients were received combined treatment of diathermy in central teared zone and cryothermy in peripheral detached area, and another 10 patients were received separately by electric diathermy (4) and by cryothermy (6) with good reattachment of 16 patients (84.2%). Combined technique of diathermy and cryothermy has a benefit by the production of strong choroiditis in detached main area resulted from diathermy and of least inflammation scars in peripheral detached zone from cryothermy. And any significant postoperative complication was not found in all cases.
Choroid ; Choroiditis ; Cicatrix ; Diathermy* ; Humans ; Inflammation ; Postoperative Complications ; Retinal Detachment* ; Retinaldehyde*

Multifocal choroiditis and panuveitis(MCP) is a clinical syndrome characterized by vitritis, and punched-out fundus lesions mimicking presumed ocular histoplasmosis. We diagnosed MCP in a twenty-eight years old woman with the complaint of decreased vision and floater symptom. Retinochoroidal anastomosis via one of retinochoroidal scars was noted in this case. The patient was treated with oral and periocular steroid and ws observed for 11 months during which choroidal neovascularization and macular edema ws not developed. We present this case because, as far as our knowledge goes, There has been no reported case of MCP with retinochoroidal anastomosis.
Choroid* ; Choroidal Neovascularization ; Choroiditis* ; Cicatrix ; Female ; Histoplasmosis ; Humans ; Macular Edema ; Panuveitis*

INTRODUCTIONTo review the long-term outcome of photodynamic therapy (PDT) with verteporfin for inflammatory chorioretinal disease with subfoveal choroidal neovascularisation (CNV) over a 1-year period.

MATERIALS AND METHODSRetrospective review of eyes with subfoveal CNV for associated choroiditis that were treated with PDT using verteporfin over a 1-year period.

MAIN OUTCOME MEASUREvisual acuity.

RESULTSFive eyes in 4 patients, with diagnoses including serpiginous choroiditis (2), ocular histoplasmosis syndrome (OHS, 1), and punctate inner choroidopathy (PIC, 2) underwent standard treatment procedure for PDT with verteporfin. Visual acuity, fluorescein angiography and treatment parameters were reviewed. Follow-up ranged from 12 months to 36 months (median, 36 months). Pre-PDT visual acuities ranged from 20/60 to 20/400 (median, 20/200). Post-PDT visual acuities ranged from 20/30 to 20/400 at 1 year (median, 20/300). Visual acuity was stabilised (within 1 line) or improved (greater than 1 line) in 3 eyes at 1 year and 4 of the 5 eyes at last follow-up.

CONCLUSIONPDT for subfoveal CNV may stabilise, but rarely improves, visual acuity in eyes with choroidal neovascularisation secondary to inflammatory chorioretinal disease.

Adult ; Aged ; Choroidal Neovascularization ; drug therapy ; etiology ; Choroiditis ; complications ; Female ; Humans ; Male ; Photochemotherapy ; Photosensitizing Agents ; therapeutic use ; Porphyrins ; therapeutic use

PURPOSE: To characterize the clinical presentation and visual prognosis of punctate inner choroidopathy in Korean patients. METHODS: Eleven patients (seventeen eyes) with punctate inner choroidopathy (PIC) and four (six eyes) with multifocal choroiditis with panuveitis (MCP) were analyzed retrospectively. RESULTS: The mean age of the PIC patients was 32.2 +/- 9.3 years and the mean refractive error was -4.79 +/- 3.18 diopters. In all PIC eyes, fundus photographs showed multiple yellowish white punctate lesions and punched-out scars at the level of the inner retina and choroid. There was no significant difference between the mean initial visual acuity (0.67 +/- 0.40) and the mean final visual acuity (0.56 +/- 0.41). The major cause of visual deterioration was choroidal neovascularization (CNV) which developed in 4 eyes. In PIC, the lesions were located in the more posterior retina and the incidence of CNV was higher than in MCP. CONCLUSIONS: PIC affects young women with moderate myopia and shows the characteristic chorioretinal lesion. Although the eye with PIC usually maintains stable vision after initial attack, CNV may cause complications and significant visual loss.
Choroid ; Choroidal Neovascularization ; Choroiditis ; Cicatrix ; Female ; Humans ; Incidence ; Korea* ; Myopia ; Panuveitis ; Prognosis ; Refractive Errors ; Retina ; Retrospective Studies ; Visual Acuity

PURPOSE: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with widespread manifestations that rarely include the eye. We present a case of SLE-associated choroidoretinopathy and secondary angle closure attack in both eyes. CASE SUMMARY: A 58-year-old male was admitted into the urologic department complaining of right scrotal swelling, and then consulted with the ophthalmology department regarding both ocular pain and eye injection. The patient was diagnosed with acute angle closure attack using a slit lamp test and tonometry secondary to choroidoretinitis with choroidal detachment at fundus examination in both eyes. The rheumatologist performed systemic evaluation, including serologic tests, and then diagnosed the patient with SLE. After systemic steroid therapy, intraocular pressure was decreased and choroidal detachment disappeared with improvements of choroidoretinitis in both eyes. CONCLUSIONS: Patients with systemic lupus erythematosus choroidopathy can develop secondary angle closure attack, which can be effectively treated using systemic steroid therapy and antiglaucoma drugs.
Choroid ; Choroiditis ; Humans ; Intraocular Pressure ; Lupus Erythematosus, Systemic* ; Male ; Manometry ; Middle Aged ; Ophthalmology ; Serologic Tests ; Slit Lamp

PURPOSE: The purpose of this study is to make a distinction between tuberculous serpiginous-like choroiditis and serpiginous choroiditis, and compare their clinical manifestations. METHODS: We retrospectively reviewed thirty eight eyes of twenty-six patients who visited our institution and were diagnosed with serpiginous choroiditis from January 2005 to December 2014. The patients were divided into two groups, tuberculosis serpiginous- like choroiditis (Tb-SLC) and classic serpiginous choroiditis (classic SC), and were analyzed based on the treatment response, previous history of Bacillus Calmette–Guérin (BCG) vaccination, positive results of tuberculin skin test (TST), chest X-ray, anterior and fundus examination, and fluorescein angiography (FAG). RESULTS: Twenty seven eyes of eighteen patients were serpiginous choroiditis and eleven eyes of eight patients were tuberculosis serpiginous-like choroiditis. There were no significant differences in age, sex, or previous history of BCG vaccination between the two groups. The positive result of the tuberculin skin test and abnormality in the chest X-ray were shown to be significantly higher in the Tb-SLC group. Multi-focal lesions involving periphery observed in fundus examination and FAG were significantly higher in Tb-SLC. CONCLUSIONS: In tuberculosis endemic areas such as Korea, tuberculosis serpiginous-like choroiditis should be considered as a differential diagnosis when the patient is suspicious of serpiginous choroiditis. The understanding of various clinical manifestations of tuberculosis serpiginous-like choroiditis may derive accurate diagnosis and treatment, enhancing patient's prognosis.
Bacillus ; Choroid* ; Choroiditis* ; Diagnosis ; Diagnosis, Differential* ; Fluorescein Angiography ; Humans ; Korea ; Mycobacterium bovis ; Prognosis ; Retrospective Studies ; Skin Tests ; Thorax ; Tuberculin ; Tuberculosis* ; Vaccination

PURPOSE: Scanning laser ophthalmoscope (SLO) has improved Infrared (IR) imaging. Since greater penetration of IR light permitted better visualization of subretinal structures, we evaluated chorioretinal layer in various chorioretinal dieases with SLO. METHODS: Cases of central serous chorioretinopathy (CSC), drusen, age-related macular degeneration (AMD), Vogt-Koyanagi-Harada disease, MEWDS (multiple evanesant white dot syndrome) and inflammatory choroiditis, toxoplasmosis, Stargardt's disease, proliferative diabetic retinopathy (PDR) and submacular hemorrhage were included. We used SLO (101, Rodenstock, Germany) for IR image and compared argon laser image with monochromatic IR image (780 nm wave length). RESULTS: The demarcation and extent of serous retinal detachment and macular star were more distinct in IR image. Small drusen, subretinal deposit and RPE atropy which could not be seen in argon green laser image were visible and appeared brightly with high reflectance in IR image. The CNV membrane which was not seen in full extent in argon laser image were observed completely in IR image. In case of inflammatory choroiditis, patch-like hot spot with surrounding high reflectance was observed in IR image. The subretinal structures and new vessels were clearly visible in IR image despite overlying thick preretinal fibrous prolifertive membrane and vitreous hemorrhage. CONCLUSIONS: The IR image using SLO is a fast and non-invasive diagnostic tool. Compared to fluorescein angiography, IR image gave a improved image for subretinal structure and additional information. Therefore IR imaging is recommended along with clinical symptom, FAG, ICGA for the diagnosis and treatment.
Argon ; Central Serous Chorioretinopathy ; Choroid ; Choroiditis ; Diabetic Retinopathy ; Diagnosis ; Fluorescein Angiography ; Hemorrhage ; Macular Degeneration ; Membranes ; Ophthalmoscopes ; Retina ; Retinal Detachment ; Toxoplasmosis ; Uveomeningoencephalitic Syndrome ; Vitreous Hemorrhage

PURPOSE: To report a case of choroidal neovascularization (CNV) secondary to candida chorioretinitis initially treated with an intravitreal bevacizumab injection. CASE SUMMARY: A 50-year-old female presented at our clinic with decreased vision and metamorphopsia in her left eye of 5 days duration. She received an anti-fungal treatment 2 months prior due to the presence of endogenous candida choroiditis in both eyes. Fluorescein angiography and optical coherence tomography (OCT) revealed juxtafoveal CNV in her left eye. Three monthly intravitreal injections of bevacizumab were administered as the initial loading dosage. Her visual symptoms improved and CNV regression was observed on OCT. No recurrence or complications were observed during the 6 month follow-up. CONCLUSIONS: Based on the present study results we suggest that intravitreal bevacizumab injection can be used to effectively treat CNV and improve visual symptoms during the treatment of juxtafoveal CNV associated with candida choroiditis.
Candida* ; Chorioretinitis* ; Choroid ; Choroidal Neovascularization* ; Choroiditis ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Intravitreal Injections ; Middle Aged ; Recurrence ; Tomography, Optical Coherence ; Vision Disorders ; Bevacizumab

Polyarteritis nodosa is a necrotizing vasculitis affecting medium and small-sized arteries throughout the body. Eye involvement is present in about 10% to 20% of patients, including chemosis, iritis, episcleritis, corneal ulcers, keratitiis, choroiditis, retinal detachment, extraocular muscle palsies, and hypertensive retinopathy. Rarely there have been reports of optic neuropathies and occasional central retinal artery occlusions. We experienced a patient with central retinal artery occlusion who had been diagnosed polyarteritis nodosa with mononeuritis multiplex.
Arteries ; Choroid ; Choroiditis ; Humans ; Hypertensive Retinopathy ; Iritis ; Mononeuropathies ; Optic Nerve Diseases ; Paralysis ; Polyarteritis Nodosa* ; Retinal Artery Occlusion* ; Retinal Artery* ; Retinal Detachment ; Scleritis ; Ulcer ; Vasculitis