One to three percent of childhood brain tumors are choroid plexus tumors. Of these, 30-40% are considered to be choroid plexus carcinoma. We report one case of choroid plexus carcinoma without parenchymal invasion, which showed rapid dissemination along whole CSF pathway and developed postoperative hydrocephalus in spite of gross total resection.
Brain Neoplasms ; Choroid Plexus Neoplasms ; Choroid Plexus* ; Choroid* ; Hydrocephalus

A 42-year-old Chinese man, known case of renal cell carcinoma with lung metastasis, was referred to Universiti Kebangsaan Malaysia Medical Centre for left eye blurring of vision for one month duration, which was worse upon waking up in the morning and cleared up after 1-2 hours. On examination, visual acuities were 6/6 in both eyes. No relative afferent pupillary defect. Left fundus showed inferonasal retinal detachment without macular involvement. No retina break, no retinitis and no choroidal lesion seen. Right eye examination was normal. Optical coherence tomography (OCT) of left eye showed subretinal fluid temporal and inferior to optic disc. Fundus fluorescein angiography (FFA) left eye showed hypofluoresence in early phase but hyperfluorescence with pin point leakage in late phase over inferonasal quadrant. Indocyanine green (ICG) showed early hypofluoresence with late pin point hyperfluoresence in the same quadrant. A clinical diagnosis of exudative retinal detachment due to choroidal metastasis secondary to renal cell carcinoma was made. The patient was planned for cyber-knife radiotherapy of his left eye but unfortunately we lost the follow up. High index of suspicion and relevant investigation are needed for patients with visual complaints and history of renal cell carcinoma to diagnose choroidal metastasis.
Carcinoma, Renal Cell ; Choroid Neoplasms

BACKGROUND: The pigmented or melanotic variant of choroid plexus carcinoma is very rarely encountered. CASE REPORT: We report herein a case of melanotic or pigmented choroid plexus carcinoma in the posterior fossa of an 11-year-old female. CONCLUSIONS: A histopathological study supported by immunohistochemistry helped the authors to diagnose this rare entity. How to differentiate this tumor from pigmented papillary medulloblastoma, cerebellar papillary ependymoma, and metastatic malignant melanoma is discussed.
Carcinoma ; Child ; Choroid ; Choroid Plexus ; Choroid Plexus Neoplasms ; Ependymoma ; Humans ; Immunohistochemistry ; Medulloblastoma ; Melanins ; Melanoma

Choroid plexus carcinoma is a rare intracranial neoplasm, affecting mainly very young children. The commonest site is within the lateral ventricles and the prognosis is very poor. We report a seven month old baby boy who presented with raised intracranial pressure and seizures. Brain CT scan showed large intraventricular mass with calcification and hydrocephalus. Total macroscopic resection of the tumour was performed and diagnosis of choroid plexus carcinoma was made. However, the patient died 11 days after the tumour excision. The histopathology of this rare childhood neoplasm is discussed.
Carcinoma/*surgery ; Choroid Plexus Neoplasms/*surgery

A Case of pigmented choroid plexus carcinoma is reported. The patient was a 35-year-old woman who had headache of 3-month duration, followed by ataxia for 1month before admission. Brain CT revealed a well enhanced mass at the left cerebello-pontine angle area as well as hydrocephalus. Subtotal removal of the tumor was performed via suboccipital craniectomy under the impression of meningioma because there was a mass only in the extraventricular area. The tumor was diagnosed by light microscopic examination. Pigmented choroid plexus carcinoma, which has been reported as low grade malignancy, is very rare and located always in the ventricles. In the case the tumor was subtotally removed and ventriculo-peritoneal shunt surgery and radiation therapy underwent later. The patient has been followed-up without recurrence for 1 year postoperatively.
Adult ; Ataxia ; Brain ; Choroid Plexus Neoplasms* ; Choroid Plexus* ; Choroid* ; Female ; Headache ; Humans ; Hydrocephalus ; Meningioma ; Recurrence ; Ventriculoperitoneal Shunt

A retrospective analysis of five adult patients with choroid plexus tumor(four choroids plexus papillomas, one choroids plexus carcinoma who underwent surgical resection at our institute between February 1991 and October 1995 was performed. The study group included two males and three females with a mean age of 34.0 years(range 21 to 24 years). Two of four choroids plexus papillomas were removed gross totally and one of these was irradiated postoperatively. The remaining two patients with choroids plexus papilloma underwent a subtotal surgical resection and one of them received radiation therapy. During follow-up, the authors could not find any difference in the size of the residual tumor or in the patient's KPS between the irradiated groups. There was also no response to postoperative radiation therapy in a patient with choroids plexus carcinoma who underwent a subtotal resection. The author's clinical experiences suggest that the use of radiation therapy in adult patients with choroids plexus tumor is not effective, and thus gross total resection should be attempted during the primary operation of such tumors.
Adult* ; Choroid Plexus Neoplasms* ; Choroid Plexus* ; Choroid* ; Female ; Follow-Up Studies ; Humans ; Male ; Neoplasm, Residual ; Papilloma ; Papilloma, Choroid Plexus ; Retrospective Studies

Transient mutism has ben known as a rare complication following a posterior fossa approach to cerebellar tumors, although its pathophysiology remains unclear. Cerebellar mutism may be defined as a transient mutism occurring after a posterior fossa tumor approach in children with unimpaired consciousness, unimpaired symbolic functions, no detectable deficit of cranial nerves or peripheral organs of speech, and no lesions of long pathways in the course of the cranial nerves at the level of the brain stem. Forty two cases in children, and only two cases in adults have been found in the literature. We report a case of transient mutism with oropharyngeal apraxia after total excision of 4th ventricle choroids plexus papilloma in a 6-year-old girl. Postoperatively, the patient became mute and refused food intake without disturbance of consciousness, or lower cranial nerve function. Computed tomography(CT) and magnetic resonance image(MRI) demonstrated no abnormal findings except the surgical lesion in the posterior fossa. The mutism lasted for 3 weeks, but she gradually became fluent. The mechanism of "cerebellar mutism" is briefly discussed with literature review.
Adult ; Apraxias ; Brain Stem ; Cerebellar Neoplasms ; Child* ; Choroid Plexus* ; Choroid* ; Consciousness ; Cranial Nerves ; Eating ; Female* ; Humans ; Infratentorial Neoplasms ; Mutism* ; Papilloma ; Papilloma, Choroid Plexus*

Metastasis of choroid from prostate cancer is not common and has not been reported before in Korea. We report a case of decreased vision in a patient with prostate cancer. After external beam radiotherapy, patient had complete response in the choroidal metastasis. Metastasis of choroid secondary to prostate is not common. There have been only 8 cases reported. In this case, we demonstrated that external beam radiotherapy showed a therapeutic effect.
Choroid* ; Humans ; Korea ; Neoplasm Metastasis* ; Prostate* ; Prostatic Neoplasms* ; Radiotherapy

Ocular metastasis of metastatic carcinoma is the most common intraocular malignancy. The most common pr1mary Site of the lntraocular metastatic tumor is the breast ln women and the lung 1n men respectlvely and the choroid Is by far the most common site for intraocular metastasis. RadlOtherapy has been reported hlghly effect1ve in pal1iative treatment for metastatic tumor. We experienced a case choroidal metastasis in a known metastatic breast carcinoma patient and gained clinical lmprovement by rad1otherapy in this case.
Breast Neoplasms* ; Breast* ; Choroid* ; Female ; Humans ; Lung ; Male ; Neoplasm Metastasis*

Choroid Plexus Neoplasms ; pathology ; Female ; Humans ; Infant ; Lateral Ventricles ; pathology