PURPOSE: The purpose of this study was to evaluate the sonographic features of normal choroid plexus, thushelping avoid misinterpretations such as intraventricular hemorrhage or abnormality. MATERIALS AND METHODS: Posterior coronal, parasagittal, and oblique sagittal scans of 400 choroid plexus in normal full-term neonates(100girls, 100 boys) were reviewed with special attention to coronal configuration, glomus patterns,and the shape ofanterior ends. Sonographic features were classified as follows ; tubular(type 1), posterior clubbing(type 2),mid-bulging(type 3), or double choroidal pattern(type 4), as seen on posterior coronal scans; crescent(type1),superior notching(type 2), dorsal bulging(type 3), or inferior notching(type 4), as seen on parasagittal scans;and anterior tapering(type 1) and clubbing shape (type 2) on oblique parasagittal scans. Maximal diameters of thechoroid plexus on posterior coronal scan and the glomus on parasagittal scan were measured. All sonographicmeasurements of normal choroid plexus were statistically analysed according to gender and side. RESULTS: Fourhundred normal choroid plexus were classified as 293 cases(73%) of tubular pattern(type 1), 50 cases(13%) ofposterior bulging(type 2), 44 cases (11%) of mid-bulging(type 3) and 13 cases(3%) of double choroidal pattern(type 4) as seen on posterior coronal scans ; 263 cases(66%) of crescent shape(type 1), 70 cases(17%) of superiornotching (type 2), 38 cases(9%) of dorsal bulging(type 3), and 29 cases(7%) of inferior notching(type 4), as seenon parasagittal scans; and 233 cases(58%) of anterior tapering(type 1) and 167 cases(42%) of anterior clubbing(type 2), as seen on oblique parasagittal scans. Maximal diameters of the choroid plexus on posterior coronal scanwere 7.17 +/-0.12 mm (95% confidence interval [CI]) on the right side and 7.13 +/-0.19mm (95% CI) on the left side,and 8.13 +/-0.24(95% CI) mm on the right and 8.57 +/-0.29mm on the left side glomus on parasagittal scan. There wereno significant statistical differences with regard to gender and side. CONCLUSION: We have observed themorphological variety of the choroid plexus in normal full-term neonates on ultrasonograms and believe that aknowledge of the various sonographic patterns involved can help differentiating normal choroid plexus fromintraventricular hemorrhage or choroidal abnormality.
Brain ; Choroid Plexus* ; Choroid* ; Hemorrhage ; Humans ; Infant, Newborn* ; Ultrasonography

PURPOSE: To report a patient with multiple subretinal and intraretinal hemorrhages in the absence of retinal/choroidal lesions, diagnosed with infective endocarditis (IE). CASE SUMMARY: We describe the case of a 44-year-old male with an acute decrease of vision in his right eye. Ophthalmic evaluation revealed multiple subretinal and intraretinal hemorrhages, but no choroidal or other retinal lesions. A systemic examination revealed a pansystolic murmur and blood cultures with echocardiography were suggestive of IE. CONCLUSIONS: Thorough systemic evaluations are important when patients present with subretinal and intraretinal hemorrhages in the absence of other retinal/choroidal lesions.
Adult ; Choroid ; Echocardiography ; Endocarditis* ; Hemorrhage* ; Humans ; Male ; Retinal Hemorrhage ; Retinaldehyde

Experimental vitreous hemorrhage was induced in rabbit eye by rupturing the choroidal vessels mechanically with a 26 gauge needle introduced into the eye through the supero-nasal quadrant of the sclera, 10mm posterior to the limbus. Absorption of vitreous hemorrhage was evaluated by indirect ophthalmoscopy in the following groups and pathological specimens were obtained three months after vitreous hemorrhage. Group I: after vitreous hemorrhage, no additional management was done for control(4 eyes). Group II: vitreous gel was disrupted mechanically with 26 gauge needle to liquefy the vitreous(4 eyes). Group III: 1cc of vitreous waS replaced with the same amount of normal saline prior to vitreous hemorrhage (4 eyes). Group IV: 0.3cc of hyaluronidase (75 units) was injected into the posterior vitreous prior to vitreous hemorrhage (4 eyes). In groups I, II, and IV, vitreous hemorrhages were completely absorbed in 8 to 10 weeks. whereas absorption time was shortened in group m to 6 to 8 weeks. Pathological specimen revealed no infiltrations of inflammatory cells, but only glial proliferations.
Absorption ; Choroid ; Hyaluronoglucosaminidase ; Needles ; Ophthalmoscopy ; Sclera ; Vitreous Hemorrhage*

Three-dimensional computed tomographic angiography (CTA), a representative noninvasive radiologic technique, is being widely used for detecting vascular lesions in specific intracranial bleeding under a certain circumstance (acute nontraumatic subarachnoid hemorrhage). We encountered a case of extravasation of the contrast medium on CTA images that appeared as ribbon-like high-attenuation lesion from an aneurysm at the distal anterior choroidal artery in a young adult moyamoya patient. As CTA is used more frequently, it is imperative to understand such unusual but, potentially lethal image findings to conduct a prompt intervention.
Aneurysm* ; Angiography* ; Arteries* ; Choroid* ; Hemorrhage ; Humans ; Moyamoya Disease ; Young Adult

PURPOSE: To evaluate the efficacy of intravitreal aflibercept monotherapy in submacular hemorrhage (SMH) secondary to wet age-related macular degeneration (AMD). METHODS: This study included 25 eyes in 25 patients with SMH involving the fovea secondary to wet-AMD. All patients were treated with three consecutive monthly intravitreal aflibercept (2.0 mg/0.05 mL) injections, followed by as-needed reinjection. They were followed for at least 6 months. Best-corrected visual acuity (BCVA), central foveal thickness (CFT), and area of SMH were measured at diagnosis, as well as at 3 and 6 months after treatment initiation. RESULTS: The BCVA significantly improved from 0.79 ± 0.41 logarithm of the minimum angle of resolution (logMAR) at baseline to 0.54 ± 0.41 logMAR at 6 months (p < 0.001). BCVA ≥3 lines and stable vision were observed in 96% of the eyes. The CFT significantly decreased from 560.8 ± 215.3 µm at baseline to 299.8 ± 160.2 µm at 6 months (p < 0.001). The area of SMH significantly decreased from 10.5 ± 7.1 mm² at baseline to 1.8 ± 6.5 mm² at 6 months (p < 0.001). The BCVA, CFT, and area of SMH at baseline, as well as duration of symptoms, all correlated with BCVA at the 6-month follow-up. CONCLUSIONS: Intravitreal injection of aflibercept is an effective treatment option for patients with SMH secondary to wet-AMD; however, there may be limited efficacy in eyes with large SMH area and cases in which treatment is delayed.
Choroid Hemorrhage ; Diagnosis ; Follow-Up Studies ; Hemorrhage* ; Humans ; Intravitreal Injections ; Macular Degeneration* ; Retinal Hemorrhage ; Visual Acuity

Bilateral traumatic hemorrhage of the basal ganglia is an extremely rare neuropathologic entity. This report describes a 50-year-old man with bilateral basal ganglia hemorrhage with occipital fracture of the skull after head trauma. The mechanism of development of traumatic hemorrhage of the basal ganglia has been not clear. But, it is presumed to be secondary to rupture of the lenticulostriate or anterior choroidal artery by shearing as a result of acceleration/deceleration forces. We briefly summarize our uncommon case and discuss its possible mechanisms.
Arteries ; Basal Ganglia Hemorrhage ; Basal Ganglia* ; Choroid ; Contusions ; Craniocerebral Trauma ; Hemorrhage* ; Humans ; Middle Aged ; Rupture ; Skull

Eyes with neovascular glaucoma often times present with vitreous hemorrhage which makes subsequent panretinal photocoagulation difficult to impossible. These eyes can benefit from pars plana vitrectomy combined with glaucoma shunt procedure. Other candidates are those refractory galucomatous eyes with severe vitreoretinal diseases that require surgical intervention. We performed standard pars plana vitrectomies in combination with Ahmed Glaucoma Valve implant and analyzed the surgical outcome in 11 eyes of 11 patiens with severe refractory galucoma. With the surgical success defined as an achievement of intraocular pressure(IOP) less or equal to 21 mmHg with anatomical reattatchment of retina, nine eyes(81.8%) became qualified in the success group. Complications included hyphema and/or severe fibrinous reaction (3 eyes), temporary IOP increase (3 eyes), recurrent vitreous hemorrhage (1 eye) and loss of light perception (1 eye). No eye showed postoperative hypotony, choroidal effusion or hemorrhage. In conclusion, in those eyes with refractory glaucoma accompanied with severe vitreoretinal disease that do not respond to the conventional IOP lowering procedures, combined pars plana vitrectomy with Ahmed Glaucoma Valve implantation may serve as a useful surgical alternative.
Choroid ; Fibrin ; Glaucoma* ; Glaucoma, Neovascular ; Hemorrhage ; Hyphema ; Light Coagulation ; Retina ; Vitrectomy* ; Vitreous Hemorrhage

Whether or not to drain the subretinal fluid in retinal detachment surgery remains controversial. The primary advantage of nondrainage procedure is the avoidance of the possible complications associated with transchoroidal drainage, such as choroidal hemorrhage, retinal perforation and loss of formed vitreous. Does the drainage of subretinal fluid itself affect the outcome of surgery? If any, what is the mandatory indication? The authors compared the surgical results of drainate vs. nondrainage of subretinal fluid in scleral buckling procedure to answer these questions. We reviewed preand postoperative characteristics of retinal detachments and the course of subretinal fluid absorption in the 66 eyes of 65 patients who received scleral buckling procedure and were followed up at least 6 months. Retinal reattachment was achieved in 23 eyes of SRF drained 26 eyes(88.4%) and 32 eyes of SRF non-drained 40 eyes(80.0%) after primary operation. The average of time for complete resorption of SFR was 8.04 significant difference was observed between the two groups. Complications associated with drainage were 2 cases of localized subretinal hemorrhage and one case of retinal perforation but did not disturb reattachment of retina. On the basis of these results, we think that placing the buckle correctly is more essential than drainage for successful retinal detachment surgery.
Absorption ; Choroid Hemorrhage ; Drainage ; Hemorrhage ; Humans ; Retina ; Retinal Detachment ; Retinal Perforations ; Retinaldehyde ; Scleral Buckling* ; Subretinal Fluid

Papilloma of the choroids plexus is rare and the incidence is about 0.4% of the verified intracranial tumors. This tumor is interesting because of its frequent association with communicating hydrocephalus and possibility of total excision with satisfactory result. We present a case of choroids plexus papilloma of the right lateral ventricle in a 5 years old girl with progressively enlarged head and walking difficulty. Pathologically the removed specimen was a 5x4x1.5 cm. sized pinkish globular mass with an irregular papillary surface. The tumor was generally edematous and showed no areas of hemorrhage or necrosis on cut sections. Microscopically the characteristic papillar consisted of single layer of mostly cuboidal and occasionally columnar epithelial cells, and were resting upon a delicate fibrous stroma containing many blood veseels. Cytoplasm of the covering epithelial cells showed slight PAS-positivity. However, neither cilia nor blepharoplast was demonstrated.
Child, Preschool ; Choroid Plexus* ; Choroid* ; Cilia ; Cytoplasm ; Epithelial Cells ; Female ; Head ; Hemorrhage ; Humans ; Hydrocephalus* ; Incidence ; Lateral Ventricles ; Necrosis ; Papilloma ; Papilloma, Choroid Plexus* ; Walking

Inflammatory pseudotumor is an uncommon lesion with unknown etiology characterized by sclerosing inflammation which clinically and radiographically mimics a neoplastic lesion. A 47-year-old man presented with sudden headache and dysarthria. Brain CT scan revealed a 2.6x2.2 cm sized, round, and hyperdense mass in the anterolateral wall of the left lateral ventricular trigone. On MR imaging studies, the mass showed low signal intensity in the wall of the trigone on T2-weighted image, central mixed (iso- and high-) signal intensity with peripheral low-signal intensity on T1-weighted image. Subtle staining of left choroid plexus with irregular shaped distal branch of anterior choroidal artery was found on the cerebral angiography. These findings suggested a small tumorous lesion originated from the left choroid plexus. During the hospital days, the mass manifested as repeated hemorrhages. The mass was successfully removed via left occipital transcortical approach. The histopathological report of the specimen was hemorrhage and fibrosis, with dense lymphoplasma cell infiltration, suggestive of an inflammatory pseudotumor.
Arteries ; Brain ; Cerebral Angiography ; Choroid ; Choroid Plexus ; Dysarthria ; Fibrosis ; Granuloma, Plasma Cell ; Headache ; Hemorrhage ; Humans ; Inflammation ; Lateral Ventricles ; Middle Aged