1.Reporting one case of abnormally high urine hCG level in the pregnancy
Journal of Vietnamese Medicine 2005;309(4):34-36
Reporting one case of abnormal high urine hCG level in the pregnancy. The abnormal high level was still in allowed limits, even higher than normal level. The maximum hCG level was observed at 11 weeks and 5 days of gestational age following the first days of the last menstrual periods. The symptoms such as nausea, vomiting would be severe with very low hCG, last until hCG achieved maximum. This patient was successfully managed with aminazin
Chorionic Gonadotropin
;
Pregnancy
;
Urine
2.Evaluation of Leukocyte and Bacterial Interference in Point-of-Care Human Chorionic Gonadotropin Tests.
John V MITSIOS ; Ann M GRONOWSKI ; Carey Ann D BURNHAM
Annals of Laboratory Medicine 2013;33(6):455-456
No abstract available.
Chorionic Gonadotropin/*urine
;
Female
;
Humans
;
Pregnancy
;
*Pregnancy Tests
3.False-positive Urine Pregnancy Test Due to Leukocyte Interference.
Hsiu Fen JAO ; Tze Kiong ER ; Jen Kuei HSIAO ; Chein Hua CHIANG
Annals of Laboratory Medicine 2012;32(2):167-168
No abstract available.
Adult
;
Chorionic Gonadotropin/*urine
;
Diagnostic Errors
;
Endometriosis/diagnosis
;
Female
;
Humans
;
Leukocytes/immunology/metabolism
;
Pregnancy
;
*Pregnancy Tests
4.Clinical Effectiveness of Urinary Human Chorionic Gonadotropin Related Protein (hCGRP) Quantification for Diagnosis of Ectopic Pregnancy.
Jae Kwan LEE ; Min Jeong OH ; Joong Sik SHIN ; Kyung Joo LEE ; Jung Hyun NAM ; Jung Hak CHA ; Jin Dong CHANG ; Dong Hee CHO ; In Soo KANG ; Paul I LEE
Journal of Korean Medical Science 2005;20(3):461-467
We detected pregnancy related new molecule, human chorionic gonadotropin related protein (hCGRP) in the urine of a pregnant women by using a monoclonal antibody against the human chorionic gonadotropin (hCG). This study examined the effectiveness of urinary hCGRP quantification in diagnosing ectopic pregnancy. This study included 40 normal pregnant women and 25 patients with ectopic pregnancy. Patients' serum and urinary intact whole hCG (i-hCG) and hCGRP concentrations were measured using sandwich ELISA and the ratio of hCGRP to i-hCG was calculated. Statistical analysis was performed using statistical package for social sciences (SPSS) 10.0. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the cut-off value to discriminate ectopic pregnancies from normal intrauterine pregnancies. Urinary hCGRP and hCGRP/i-hCG ratio in ectopic pregnancy group (14 +/- 6.6 ng/mL, 4.6 +/- 1.9%, respectively) were significantly lower than those of normal pregnancy group (149 +/- 10.2 ng/mL, 29.7 +/- 1.9%, respectively; p<0.001). Based on ROC curve analysis, a cut-off point of urinary hCGRP/i-hCG ratio <16.2% discriminated between ectopic pregnancy and normal pregnancy with a sensitivity, specificity, positive predictive value and negative predictive value of 92.0%, 90.0%, 32.6%, and 99.5%, respectively. Urinary hCGRP/i-hCG ratio measurement may be effective in diagnosing ectopic pregnancy.
Adult
;
Antibodies, Monoclonal/immunology
;
Chorionic Gonadotropin/*diagnostic use/immunology/urine
;
Enzyme-Linked Immunosorbent Assay/methods
;
Female
;
Humans
;
Pregnancy
;
Pregnancy, Ectopic/*diagnosis/urine
;
Sensitivity and Specificity