Huntington's disease (HD), an autosomal dominant dominant disorder of mid-life onset, is characterized by progressive involuntary choreiform movement, psychological change and dementia. We present here one case of Huntington's disease, who was admitted at Seoul National University Hospital from 2nd Oct. to 16 Oct. 1985.
Chorea ; Dementia ; Huntington Disease ; Seoul

Huntington's Disease (HD), an autosomal dominant disorder of mid-life onset, is characterized by progressive involuntary choreiform movement, psychological change and dementia. We present here two cases of Huntington's disease. One case has family history, but the other has none.
Chorea ; Dementia ; Humans ; Huntington Disease*

Huntington's disease(HD) is a neurcdegenerative disorder caused by a highly penetrant autosomal dominant genetic defect. It is characterized by adult onset progressive chorea, psychological change, and dementia with relentless deterioration. Until now the reported cases are very rare in Korea, so we presented here two cases of definite HD.
Adult ; Chorea ; Dementia ; Humans ; Huntington Disease* ; Korea

No abstract available.
Chorea* ; Humans

No abstract available.
Chorea ; Hypoglycemia

No abstract available.
Chorea* ; Humans ; Moyamoya Disease*

No abstract available.
Chorea ; Creutzfeldt-Jakob Syndrome

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease characterized by a triad of progressive motor dysfunction, cognitive decline and psychiatric disturbances. The hallmark of HD is the distinctive choreiform movement disorder that typically has a subtle, insidious onset in the fourth to fifth decade of life and gradually worsens over 10 to 20 years until death. Notably, two-thirds of HD patients present with chorea and one third with mental changes. The prevalence of psychiatric symptoms is significantly higher than in the general population, and is estimated to be around 66–73%. Here, we report a unique case of subsequent onset of HD in a patient previously treated for schizophrenia and complicated by the extrapyramidal side effects to antipsychotics.
Antipsychotic Agents ; Chorea ; Humans ; Huntington Disease* ; Neurodegenerative Diseases ; Prevalence ; Psychotic Disorders* ; Schizophrenia

The differential diagnosis of chorea can be challenging in patients without a family history of Huntington's disease or acute-onset hemichorea with stroke. A 50-year-old woman presented with generalized choreic movements and gait disturbance that first appeared 1 month previously. An extensive diagnostic workup including genetic testing, neuroimaging, and various laboratory investigations revealed that this patient had developed chorea as a result of mercury poisoning. She was treated successfully with chelation therapy.
Chelation Therapy ; Chorea ; Diagnosis, Differential ; Female ; Gait ; Genetic Testing ; Humans ; Huntington Disease ; Mercury Poisoning ; Neuroimaging ; Stroke

The differential diagnosis of chorea can be challenging in patients without a family history of Huntington's disease or acute-onset hemichorea with stroke. A 50-year-old woman presented with generalized choreic movements and gait disturbance that first appeared 1 month previously. An extensive diagnostic workup including genetic testing, neuroimaging, and various laboratory investigations revealed that this patient had developed chorea as a result of mercury poisoning. She was treated successfully with chelation therapy.
Chelation Therapy ; Chorea ; Diagnosis, Differential ; Female ; Gait ; Genetic Testing ; Humans ; Huntington Disease ; Mercury Poisoning ; Neuroimaging ; Stroke