Huntington's Disease (HD), an autosomal dominant disorder of mid-life onset, is characterized by progressive involuntary choreiform movement, psychological change and dementia. We present here two cases of Huntington's disease. One case has family history, but the other has none.
Chorea ; Dementia ; Humans ; Huntington Disease*

Huntington's disease (HD), an autosomal dominant dominant disorder of mid-life onset, is characterized by progressive involuntary choreiform movement, psychological change and dementia. We present here one case of Huntington's disease, who was admitted at Seoul National University Hospital from 2nd Oct. to 16 Oct. 1985.
Chorea ; Dementia ; Huntington Disease ; Seoul

Huntington's disease(HD) is a neurcdegenerative disorder caused by a highly penetrant autosomal dominant genetic defect. It is characterized by adult onset progressive chorea, psychological change, and dementia with relentless deterioration. Until now the reported cases are very rare in Korea, so we presented here two cases of definite HD.
Adult ; Chorea ; Dementia ; Humans ; Huntington Disease* ; Korea

No abstract available.
Chorea* ; Humans

No abstract available.
Chorea ; Hypoglycemia

No abstract available.
Chorea* ; Humans ; Moyamoya Disease*

No abstract available.
Chorea ; Creutzfeldt-Jakob Syndrome

This is a case report of 47 year-old male patient with Huntington's chorea. Huntington's chorea is a progressive neurodegenerative disorder with autosomal dominant inheritance. The first symptoms of Huntington's chorea usually occur in the fourth to fifth decade and the gene is complete penetrance. The disease is characterized by both progressive motor abnormality, typically chorea, and intellectual deterioration commonly accompanied by prominent psychiatric symptoms including severe depression. Although the prevalence of Huntington's chorea is only 5-10 in 100,000 in Europe, the reported cases are extremely rare in this country until now.
Chorea ; Depression ; Europe ; Humans ; Huntington Disease* ; Male ; Middle Aged ; Neurodegenerative Diseases ; Penetrance ; Prevalence ; Wills

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease characterized by a triad of progressive motor dysfunction, cognitive decline and psychiatric disturbances. The hallmark of HD is the distinctive choreiform movement disorder that typically has a subtle, insidious onset in the fourth to fifth decade of life and gradually worsens over 10 to 20 years until death. Notably, two-thirds of HD patients present with chorea and one third with mental changes. The prevalence of psychiatric symptoms is significantly higher than in the general population, and is estimated to be around 66–73%. Here, we report a unique case of subsequent onset of HD in a patient previously treated for schizophrenia and complicated by the extrapyramidal side effects to antipsychotics.
Antipsychotic Agents ; Chorea ; Humans ; Huntington Disease* ; Neurodegenerative Diseases ; Prevalence ; Psychotic Disorders* ; Schizophrenia

The differential diagnosis of chorea can be challenging in patients without a family history of Huntington's disease or acute-onset hemichorea with stroke. A 50-year-old woman presented with generalized choreic movements and gait disturbance that first appeared 1 month previously. An extensive diagnostic workup including genetic testing, neuroimaging, and various laboratory investigations revealed that this patient had developed chorea as a result of mercury poisoning. She was treated successfully with chelation therapy.
Chelation Therapy ; Chorea ; Diagnosis, Differential ; Female ; Gait ; Genetic Testing ; Humans ; Huntington Disease ; Mercury Poisoning ; Neuroimaging ; Stroke