We report a case of squamous cell carcinoma arising in giant porokeratosis in an 88-year-old woman. She had a 20 × 12 cm sized erythematous scaly patch with central ulceration on the right parietal area. On histopathologic examination, a skin biopsy specimen from the peripheral ridge of erythematous lesion revealed porokeratosis, and a specimen from the central ulceration showed well differentiated squamous cell carcinoma.
Aged, 80 and over ; Biopsy ; Carcinoma, Squamous Cell* ; Epithelial Cells* ; Female ; Humans ; Porokeratosis* ; Rabeprazole ; Skin ; Ulcer

No abstract available.
Leg* ; Myocutaneous Flap*

Anesthesia, Local ; Bite Force ; Dental Implants ; Epistaxis ; Humans ; Mandible ; Maxilla ; Maxillary Sinus ; Maxillary Sinusitis ; Molar ; Oroantral Fistula ; Osteotomy ; Recurrence ; Splints ; Tooth

We have experienced a case of Di Guglielmo Syndrome in a 15 years old girl who had the cheif complaints of dizziness, gereral malaise and fine pustules around the nose. It is a systemic hemopathy characterized by abnormal proliferation of defective erythroid and myeloid cells and is a rare disease in childhood. The peripheral blood showed many rubriblasts, myeloblasts, metamyelocytes and bone marrow also showed atypical prorubricytes and bizzar multinucleated rubriblasts. Brief review of related literatures was made.
Adolescent ; Bone Marrow ; Dizziness ; Female ; Granulocyte Precursor Cells ; Humans ; Myeloid Cells ; Nose ; Rare Diseases

BACKGROUND/AIMS: We measured the brachial artery pulse wave velocity (BaPWV) and intima-media thickness (IMT) of the common carotid artery to evaluate atherosclerosis in young women with systemic lupus erythematosus (SLE) and healthy controls. METHODS: Twenty-one premenopausal female patients with SLE and 21 healthy controls were enrolled. The groups were matched for age, sex, ethnicity, and atherosclerosis risk factors. Smokers and those with the atherosclerosis risk factors hypertension and diabetes were excluded from this study. IMT was measured with high-resolution ultrasonography. BaPWV was measured with volume plethysmography. RESULTS: The mean age was 34.20 years in the SLE group and 36.87 years in the healthy controls. The IMT of the right and left common carotid arteries in the SLE group did not differ significantly from that in the healthy controls. The BaPWV was significantly higher in the right (1.40+/-0.26 vs. 1.17+/-0.09 cm/sec, mean+/-SD; p=0.003) and left (1.41+/-0.26 vs. 1.19+/-0.08 cm/sec, p=0.013) arms in the SLE group than in the healthy controls. There were no significant differences in the ankle-brachial pressure index (ABI), body mass index (BMI), C-reactive protein (CRP), total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, lipoprotein a, and homocysteine between the two groups. CONCLUSIONS: The IMT in premenopausal women with SLE was not significantly different from that in healthy controls, while the BaPWV, which reflects arterial stiffness, was significantly higher than in the healthy controls.
Arm ; Atherosclerosis ; Body Mass Index ; Brachial Artery ; C-Reactive Protein ; Carotid Artery, Common ; Cholesterol ; Female ; Homocysteine ; Humans ; Hypertension ; Lipoprotein(a) ; Lipoproteins ; Lupus Erythematosus, Systemic ; Pulse Wave Analysis ; Risk Factors ; Vascular Stiffness

Amyloidosis is a rare disease which is characterized by the deposition of a histochemically specific substance called amyloid in many tissue bodies, and causes various symptoms according to the organs involved. Amyloid is usually recognized by its staining reaction with Congo red stain. Primary pulmonary amyloidosis is very rare. Nodular pulmonary amyloidosis is an uncommon entity that usually manifests itself as an asymptomatic incidental finding on the chest roentgenogram and is misdiagnosed as lung cancer or pulmonary tuberculosis.
Amyloid ; Amyloidosis* ; Congo Red ; Incidental Findings ; Lung Neoplasms ; Rare Diseases ; Thorax ; Tuberculosis, Pulmonary

Amputation ; Bone Marrow ; Deglutition ; Eagles ; Glossopharyngeal Nerve Diseases ; Hardness ; Ligaments ; Pharynx

A case of tubular duplicatio of the ileum in a 2 months old infant was presented. This patient was admitted because of abdominal distention and poor general condition. Operation revealed long tubular duplicated blind intestine, measuring 57X5cm in size. The pathologic diagnosis confirmed duplication of the ileum. The patient was discharged without any complication on the 17 th postoperative day. A brief review of literature was made.
Diagnosis ; Humans ; Ileum* ; Infant ; Intestines

BACKGROUND AND PURPOSE: Elevated plasma total homocysteine (tHcy) levels are reported to be associated with an increased risk of Alzheimer's disease (AD). However, the mechanism by which homocysteine contributes to the pathogenesis of AD is as yet unknown. The aim of this study was to elucidate the relationship between white matter changes (WMC) and medial temporal lobe atrophy (MTA) on brain magnetic resonance imaging (MRI), and plasma levels of tHcy in AD patients. METHODS: Seventy-two patients with a clinical diagnosis of probable AD were recruited to the study. Plasma tHcy levels, vascular risk factors, and WMC and MTA on brain MRI were evaluated in all patients. The AD patients were classified into two groups: those with no or minimal WMC (69.2+/-8.8 years, mean+/-SD, n=36) and those with moderate-to-severe WMC (74.6+/-4.6 years, n=36) on brain MRI. RESULTS: In a univariate logistic regression analysis, the risk of moderate-to-severe WMC in AD was significantly associated with increasing age, female gender, lower education level, hypertension, high plasma tHcy levels, and lower Mini-Mental State Examination (MMSE) score. Multivariate logistic regression analysis revealed only high plasma tHcy as the independent and significant risk factor for moderate-to-severe WMC [odds ratio (OR; adjusted for age, gender, education level, MMSE score, and hypertension comparing the top tertile - tHcy levels > or =12.9 micromol/L - with the bottom tertile - tHcy levels < or =9.4 micromol/L)=7.35; 95% confidence interval, confidence interval=1.36-39.84; p=0.02], and age as a borderline significant risk factor (OR=1.08, 95% CI=0.99-1.19, p=0.09) in AD patients. Plasma tHcy levels were not correlated significantly with either right or left MTA. CONCLUSIONS: Our results suggest that the vascular pathway mediates the association between elevated plasma tHcy levels and AD.
Alzheimer Disease ; Atrophy ; Brain ; Female ; Glutamates ; Guanine ; Homocysteine ; Humans ; Hypertension ; Leukoaraiosis ; Logistic Models ; Magnetic Resonance Imaging ; Plasma ; Risk Factors ; Temporal Lobe ; Pemetrexed

A 8-yrs-old boy was admitted because of convulsion and coma. The diagnosis of Cushing's syndrome(key word) associated with hypertensive encephalopathy(key word) due to right adrenocortical carcinoma(key word) was made by clinical features, biochemical studies, radiological studies and pathological examination. The tumor was successfully resected by right adrenalectomy. But 22 months later after operation, he died of dyspnea and heart failure. A brief review of literature was presented.
Adrenalectomy ; Coma ; Cushing Syndrome* ; Diagnosis ; Dyspnea ; Heart Failure ; Humans ; Hypertension ; Hypertensive Encephalopathy* ; Male ; Seizures