No abstract available.
Granuloma* ; Microsporum* ; Tinea*

Microscopic polyangiitis (MPA) is characterized by pauci-immune necrotizing small vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation. The kidney is the most often affected organ in the majority of patients with MPA, and renal manifestations are usually the first symptoms. Glomerular capillaries are affected most often, resulting in necrotizing glomerulonephritis, usually in a crescent formation, with no or few immune deposits able to be demonstrated at the sites of vasculitis and glomerulonephritis. We report a case of microscopic polyangiitis in both legs with pitting edema in a 50-year-old female. Laboratory findings showed hematuria, proteinuria, and a positive peripheral antineutrophil cytoplasmic antibody. A renal biopsy revealed pauci-immune splitting and necrotizing capillary loop walls necrotizing vasculitis and membranoproliferative glomerulonephritis (MPGN). With a diagnosis of MPA, she has been managed with high dose steroid and cyclophosphamide. To our knowledge, this is the first reported case of MPA with MPGN.
Antibodies, Antineutrophil Cytoplasmic ; Biopsy ; Capillaries ; Cyclophosphamide ; Edema ; Female ; Glomerulonephritis ; Glomerulonephritis, Membranoproliferative ; Glycosaminoglycans ; Hematuria ; Humans ; Inflammation ; Kidney ; Leg ; Microscopic Polyangiitis ; Middle Aged ; Proteinuria ; Vasculitis

Human immunodeficiency virus infection is associated with a variety of rheumatic manifestations. The pathogenic mechanisms are not well defined, but evidences suggests multiple mechanisms, including direct or indirect human immunodeficiency virus involvement with a genetic, immunological, and environmental basis. Rheumatic manifestations can occur during the course of human immunodeficiency virus infection, and their presence is associated with an overall poor prognosis for the underlying human immunodeficiency virus infection. We report a case of a 37-year-old male who had ankylosing spondylitis with a human immunodeficiency virus infection.
Adult ; HIV ; Humans ; Male ; Prognosis ; Rheumatic Diseases ; Spondylitis, Ankylosing

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease is an inflammatory arthropathy that is defined by the deposition of CPPD crystals in articular and periarticular structures. CPPD crystal deposition disease has various clinical manifestation patterns ranging from an absence of symptoms to a severely destructive arthropathy. CPPD crystal deposition disease very rare with rheumatoid arthritis or systemic sclerosis. We report a case of CPPD crystal deposition disease combined in a patient with rheumatoid arthritis and systemic sclerosis.
Arthritis, Rheumatoid ; Calcium Pyrophosphate ; Diphosphates ; Humans ; Scleroderma, Systemic

This study is to evaluate the clinicopathologic characteristics of esophageal cancer and to assess its surgical outcome according to these clinicopathologic features. A retrospective analysis was performed for 90 esophageal cancer patients who had undergone a radical esophagectomy or a palliative operation by the one surgeon at the Department of Surgery, Yonsei University, College of Medicine, from Jan. 1990 to Aug. 1996. The survival rates were calculated by the Kaplan-Meier method. The middle one-third of the esophagus was the most frequent site with 48 cases. T3 depth of invasion was present in 53 cases (57%) at the time of operation and a superficial depth in 18 cases (20%). The rates of lymph-node metastasis was 25% in T1; 47% in T2; 66% in T3 or more. 40 patients were in stage I, 23 in IIa, 13 in IIb, 33 in III, and 7 in IV. A transhiatal esophagectomy(THE) was performed in 28 cases, and a 3-staged radical esophagectomy (transthoracic radical esophagectomy; TTRE) was done in 56 cases. The most common early postoperative complication was hoarseness, but it disappeared within 6 months. The commonly noted late complication was esophageal stricture, and it was corrected by Savary-Guillard dilatation. The leading cause of death during the follow-up period was recurrence; it was about 30 cases(33%). The survival rates according to lymph-node metastasis were 50.1% for lymph-node negative cases and 16.3% for, lymph-node positive cases. The survival rates according to depth of invasion were 83.3% in mucosa confined cases, 46.7% in submucosa invasion cases, 30.3% in muscularis propria invasion cases, and 36.5% in adventitia invasion cases. The five-year survival rates according to stage were 56.4% in stage I, 51% in stage IIa, 48% in IIb, and 33.1% in III. From this study, it can be concluded that the frequent numbers of early esophageal lesions in our study may have been a major factor in the relatively high survival rate; also the low operative mortality rate encourages us to use surgical resection for the treatment of esophageal cancer.
Adventitia ; Cause of Death ; Dilatation ; Esophageal Neoplasms* ; Esophageal Stenosis ; Esophagectomy ; Esophagus ; Follow-Up Studies ; Hoarseness ; Humans ; Mortality ; Mucous Membrane ; Neoplasm Metastasis ; Postoperative Complications ; Recurrence ; Retrospective Studies ; Survival Rate

The double pylorus is a rare condition consisting of a double communication between gastric antrum and duodenal bulb. Some investigators postulate that the doubling of the pyloric channel is a congenital phenornenon, but others believe that it is an acquired lesion. A 72 year-old-man was admitted to this hospital because of epigastric pain for 1 month. Upper G-I series revealed thickened rnucosal folds of pylorus and duodenal bulb and dilated, deformed duodenal bulb filled with barium materials. Endoscopic findings also showed two ovoid large openings of the pyloric channel divided by smooth thickened septum and multiple gastroduodenal ulcers. We thought that this case was an acquired lesion. The relevant literatures on the subject were reviewed.
Barium ; Duodenal Ulcer ; Humans ; Peptic Ulcer ; Pyloric Antrum ; Pylorus* ; Research Personnel ; Stomach Ulcer

Laryngeal involvement in systemic lupus erythematosus (SLE) is rare. It can range from mild ulcerations, vocal cord paralysis, and edema to necrotizing vasculitis with airway obstruction. The causes of vocal cord paralysis included vasculitis of the vasa nervorum, neuritis, thromboembolic effect on recurrent laryngeal nerves, and compression of the left recurrent laryngeal nerve by an enlarged left pulmonary artery. Few cases on the association of vocal cord palsy and pulmonary hypertension in SLE patient have been reported. We report a case of left vocal cord palsy and pulmonary hypertension in a patient with SLE who experienced improvement of vocal cord palsy and dyspnea after steroid pulse therapy.
Airway Obstruction ; Dyspnea ; Edema ; Humans ; Hypertension, Pulmonary* ; Lupus Erythematosus, Systemic* ; Neuritis ; Pulmonary Artery ; Recurrent Laryngeal Nerve ; Ulcer ; Vasa Nervorum ; Vasculitis ; Vocal Cord Paralysis* ; Vocal Cords*

Malignancy may cause variable musculoskeletal symptoms which resemble connective tissue disorder. This symptoms as a fine sign of hidden neoplasm can precede the diagnosis of underlying malignancy. But only one case of stomach cancer associated with cancer arthritis was reported in the world. This fact is very interesting in Asia which has high prevalence of stomach cancer. We experienced one case of gastric adenocarcinoma with oligoarthritis involving both knee and right elbow. A 48-year-old man was diagnosed stomach cancer by gastric endoscope and biopsy. After then, he complained pain, tenderness, heating sensation, swelling of both knee and right elbow with high fever. Both knee MRI showed abundant synovial effusion and soft tissue edema. Full dose of nonsteroidal anti-inflammatory drug was not effective to control fever and arthritis. But fever and arthritis were gone after resection of tumor.
Adenocarcinoma* ; Arthritis ; Asia ; Biopsy ; Connective Tissue ; Diagnosis ; Edema ; Elbow ; Endoscopes ; Fever ; Heating ; Hot Temperature ; Humans ; Knee ; Magnetic Resonance Imaging ; Middle Aged ; Prevalence ; Sensation ; Stomach Neoplasms

Drug-induced lupus erythematosus is defined as a lupus-like syndrome related to continuous drug exposure which resolves after discontinuation of the offending drug. Here we report a case of a 70-year-old man who developed drug-induced lupus erythematosus after receiving angiotensin converting enzyme inhibitor medication for unstable angina pectoris, for 5 years. He was hospitalized with arthralgia, edema, and newly developed pleural effusion. The serum analysis revealed an elevated level of antinuclear antibody and antihistone antibody. After discontinuation of angiotensin converting enzyme inhibitor and receiving a course of prednisolone treatment, his symptoms and pleural effusion improved. To the best of our knowledge, this is, the first case report of angiotensin converting enzyme inhibitor-induced systemic lupus erythematosus in Korea.
Aged ; Angina, Unstable ; Angiotensins ; Antibodies, Antinuclear ; Arthralgia ; Edema ; Humans ; Korea ; Lupus Erythematosus, Systemic ; Peptidyl-Dipeptidase A ; Pleural Effusion ; Prednisolone

A mesenchymal chondrosarcoma is a rare malignant tumor occurring in both the bone and soft tissues, and has the characteristics of a malignant nature. Since its original description in 1959, several reports of this tumor occurring in the maxilla, mandible, rib and spine have been published. We report a case of a mesenchymal chondrosarcoma that occurred in the posterior part of C7, T1 and T2 and adjacent muscles in a 31-year-old man who was treated with a wide marginal excision.
Adult ; Chondrosarcoma, Mesenchymal* ; Humans ; Mandible ; Maxilla ; Muscles* ; Ribs ; Spine