No abstract available.
Duodenal Obstruction*

Releasable suture was used to control anterior chamber depth and intraocular pressure during early postoperative period following trabeculectomy. Failure of releasable suture removal was due to entrapping of the tissue into suture knot or fibrosis between suture and surrounding tissues. Hence, the authors compared the failure rate of transconjunctival releasable suture and transcorneal releasable suture in trabeculectomy. The authors evaulated the 60 eyes of 60 patients undergoing trabeculectomy. Of these eyes, 30 eyes did not use Mitomycin C and transconjuctival releasable suture(15eyes) and transcorneal releasable suture(15eyes) at 2weeks after trabeculectomy, and the other 30 eyes used Mitomycin C and were removed transconjuctival releasable suture(15eyes) and transcorneal releasable suture(15eyes) removed at 4 weeks after trabeculectomy. With Mitomycin C, failure rate of releasable suture removal was 87% in transconjunctival releasable suture and 33% in transcorneal releasable suture. Without Mitomycin C, failure rate of releasable suture removal was 73% in transconjunctival releasable suture and 7% in transcorneal releasable suture. Recently, we have commonly used thin suture material such as 10-0 nylon and with use of antimetabolite let releasable suture was removed at late time. We suggest that transcorneal releasable suture can reduce the fibrosis of subconjunctival tissue and reaction between suture material and subconjunctival tissue.
Anterior Chamber ; Fibrosis ; Humans ; Intraocular Pressure ; Linear Energy Transfer ; Mitomycin ; Nylons ; Postoperative Period ; Sutures* ; Trabeculectomy*

Acropustulosis of infancy is an uncommon, but not rare syndrome established as a new disease entity by Kahn and Rywlin(1976), which is characterized by recurrent, intensely pruritic vesicopustules on the distal extremities. We'd like to report a case of acropustulosis of infancy. Our patient was 19 month old girl who had been suffering from her skin disease since the age of 12 months. Intensely pruritic, 1 to 2 mm vesicopustules erupted on the palms, soles and the ventral aspects of the fingers. There were no bacteria, fungus and parasites(Sarcoptes scabiei) on the pustular lesions. Histopathologically, biopsy specimen of the left sole revealed large, well circumscribed intraepidermal pustule which was filled wth polymorphonuclear leukocytes. We confirmed our case as typical case of acropustulosis of infancy by it's characteristic clinical features and histopathologic findings. Severity of the skin lesions seems closely related to the dosage of dapsone. The eruptions were unresponsive to topical steroid, antibiotics and antihistaminics. But we observed that dapsone has dose dependent relationship with acropustulosis of infancy.
Anti-Bacterial Agents ; Bacteria ; Biopsy ; Dapsone ; Extremities ; Female ; Fingers ; Fungi ; Humans ; Infant ; Neutrophils ; Skin ; Skin Diseases

Evaluation of a fever of unknown origin (FUO) is complex. Recently, PET scanning has been approved for screening in FUO evaluation. We treated three cases of FUO associated with increased FDG uptake in the bone marrow of the femur and tibia on the fusion PET/CT; all three had the same pattern of uptake. Bone marrow biopsies revealed mature lymphocyte and histiocyte infiltration and myxoid changes in one case, and cortical bone involvement in another case. The cases were all young females who had fever with neutropenia and relative lymphocytosis that lasted for several weeks and then remitted spontaneously. Even though the results of the studies were not diagnostic, the unique uptake pattern on PET/CT and the histology might be related to the cause of the illness and should be studied further to assess the association with classic FUO.
Biopsy ; Bone Marrow ; Female ; Femur ; Fever ; Fever of Unknown Origin ; Histiocytes ; Humans ; Lymphocytes ; Lymphocytosis ; Mass Screening ; Neutropenia ; Positron-Emission Tomography ; Tibia

The success rate of endoscopic dacryocystorhinostomy in epiphopa patients was evaluated. We anaylzed 57 patients, 62 cases from February 1997 to March 1998. Mean follow-up period was 7.17 months. There were 51 cases(82.3%) of female Causes of the disease were idiopathic(52 cases), trauma(3 cases) and congenital(3 cases). Primary success rate was 67.8% while total success rate was 80.6%. We used mitomycin C in 20 cases. Primary success rate in mitomycin C used group was 70.6% while total success rate was 95.0%. The success rate in mitomycin C used group was higher than that without mitomycin C. Endoscopic darcryocystorhinostomy has advantages such as less scar and short postoperarive recovery time but low success rate limits its use. However the success rate in endoscopic dacryocystorhinostomy is incresasing due to surgical improvement and instrument development.
Cicatrix ; Dacryocystorhinostomy ; Female ; Follow-Up Studies ; Humans ; Mitomycin

BACKGROUND AND PURPOSE: Periodic limb movements (PLM) during sleep (PLMS) are associated with cortical and cardiovascular activation. Changes in cerebral hemodynamics caused by cortical activity can be measured using near-infrared spectroscopy (NIRS). We investigated oscillatory components of cerebral hemodynamics during PLM and different sleep stages in restless legs syndrome (RLS) patients with PLMS. METHODS: Four female RLS patients with PLMS, and four age- and sex-matched normal controls were included. PLM and sleep stages were scored using polysomnography, while the spontaneous cerebral hemodynamics was measured by NIRS. The phase and amplitude of the cerebral oxyhemoglobin concentration [HbO] and the deoxyhemoglobin concentration [Hb] low-frequency oscillations (LFOs) were evaluated during each sleep stage [waking, light sleep (LS; stages N1 and N2), slow-wave sleep (stage N3), and rapid eye movement (REM) sleep]. In RLS patients with PLMS, the cerebral hemodynamics during LS was divided into LS with and without PLM. RESULTS: The cerebral hemodynamics activity varied among the different sleep stages. There were changes in phase differences between [HbO] and [Hb] LFOs during the different sleep stages in the normal controls but not in the RLS patients with PLMS. The [HbO] and [Hb] LFO amplitudes were higher in the patient group than in controls during both LS with PLM and REM sleep. CONCLUSIONS: The present study has demonstrated the presence of cerebral hemodynamics disturbances in RLS patients with PLMS, which may contribute to an increased risk of cerebrovascular events.
Extremities* ; Female ; Hemodynamics* ; Humans ; Oxyhemoglobins ; Polysomnography ; Restless Legs Syndrome* ; Sleep Stages ; Sleep, REM ; Spectroscopy, Near-Infrared*

Internuclear ophthalmoplegia is a conjugated gaze disorder characterized by impaired adduction on the side of a lesion involving the medial longitudinal fasciculus with dissociated nystagmus of the other abducting eye. Six patients with INO (who had clinical cerebrovascular diseases) underwent MR imaging and the results were as follows: 1. The MLF lesions were identified by MR imaging in 5 cases 2. The ratio of unilateral INO to bilateral INO was 5:1 3. The nature of lesions was infarction in 4 cases and hemorrhage in 1 case 4. The sites of MLE lesion were in the midbrain in 4 cases and in the pons in 1 case 5. All 5 cases of INO identified by MR imaging had other lesion sites in addition to MLE lesion.
Cerebrovascular Disorders* ; Hemorrhage ; Humans ; Infarction ; Magnetic Resonance Imaging* ; Mesencephalon ; Nystagmus, Pathologic ; Ocular Motility Disorders* ; Pons

No abstract available.

We have investigated endocrine functions of 2 patients with Wilson's disease who showed oligomenorrhea or amenorrhea, The serum basal levels of hypothalamic, pituitary, thyroid, adrenal cortical and ovarian hormones were determined. Then stimulation tests were performed with GnRH(50 microgram/m2), TRH(7 microgram/Kg) and insulin(0.l U/Kg) in one intravenous bolus, Levels of LH, FSH, prolactin, GH, TSH, total testosterone, l7 beta-estradiol, free T3, T4, DHEA-S and cortisol were measured by standard radioimmunoassays. The endocrine profiles which represent functions of hypothalamus, pituitary, thyroid and adrenal cortex was all proved to be normal. Serum estradiol and total testosterone levels were 59.0 microgram/ml ( normal ; 60-130 microgram/ml) and 2.9 ng / dl (normal ; 0.l5-1.1 ng/dl) in one case, and 20.5 microgram / ml and 0.69 ng / dl in the other respectiviely. Low estradial and high total testosterone levels seen in these cases suggested ovarian dysfuncton. Interference of ovarian follicular aromatase activity due to passible copper intoxication could explain these findings as the cause of the menstrual irregularity of patients with Wilson's disease.
Adrenal Cortex ; Amenorrhea ; Aromatase ; Copper ; Estradiol ; Female ; Hepatolenticular Degeneration* ; Humans ; Hydrocortisone ; Hypothalamus ; Oligomenorrhea ; Prolactin ; Radioimmunoassay ; Testosterone ; Thyroid Gland

Recent studies have demonstrated that the patients with psoriasis have various immune alternation in both humoral and cellular immunities. However the results of these are still controversial. These facts promoted us to analyze the immune cells (T cell, T subsets and B cell) by rosette method for these cells in peripheral blood of 15 patients with psoriasis. And we also analyzed the effects of photo- chemotherapy(PUVA) on these cells. The results were summerized as follows; 1. The mean values of T cell, T, T, cell and B cell in peripheral blood of the- patients with psoriasis before PUVA therapy were 56. 2+-5.7%, 35.1+-6.9%, 5. 5+l.4%, 11.6+4. 0% respectively, These results of immune cells showed signi- ficantly lower mean values when these were compaired with the mean values. of nomnal control group(T cell; 65. 2+-2.9%, TM cell; 45.8+-3.2%, T cell; 7.3+ 1.3% B cell; 16.2+2.4%), respectively (T cell, Tm Tg, p<0.01, B cell; p<0.05). 2. The mean values of T cell, T, T, cell and B cell in peripheral blood (countinue..)
Humans ; Immunity, Cellular ; Photochemotherapy* ; Psoriasis* ; PUVA Therapy