No abstract available.
Humans ; Mental Competency* ; Research Subjects*

OBJECTIVE: It has been suggested that folate deficiency can cause psychiatric disturbances of depressive nature and the possible pathogenetic mediating mechanism is the deflect in methylation processes of S-adenosylmethionine in the nervous system. But the direct causal relationship between folate deficiency and depression is not well defined and the studies to investigate the effect of folate supplementation on the treatment of depression have shown to be controversial. So this present paper aims to test the adjunctive effect of folate to antidepressant and to investigate the relationship between folate deficiency and depression. METHOD: The subjects were 30 female unmedicated outpatients with major depressive disorder by DSM-IV and they were divided into the experimental(n=15) and control group (n=15). Folate, 15 mg/day, and sertraline, 50 mg/day, were given to the experimental group for 6 weeks and sertraline, 50 mg/day for 6 weeks, was given to the control group. Response to treatment was determined by Hamilton Depression Rating Scale at baseline, 2nd week,4th week and 6th week. RESULTS: After 6 weeks treatment, the Hamilton Depression Rating Scale scores were reduced, but there was no difference between experimental and control group. CONCLUSIONS: This result does not support the supplemental application of folate for the treatment of depression, so folate deficiency does not have a common association of depressive symptoms.
Depression* ; Depressive Disorder, Major ; Diagnostic and Statistical Manual of Mental Disorders ; Female ; Folic Acid* ; Humans ; Methylation ; Negotiating ; Nervous System ; Outpatients ; S-Adenosylmethionine ; Sertraline

PURPOSE: The purpose of this study is to find helpful MR findings for predicting a naplastic oligodendrogl lomas. MATERIALS AND METHODS: Retrospective analysis of 46 MR images and 37 CT scans was performed for 46 patients with pathologically-proven cerebral oligodendrogliomas. A neuropathologist graded the tumors as one of low-grade (n=16), intermediate-grade (n=l2), or anaplastic oligodendroglioma (n=18). MR imaging features were retrospectively analysed with respect to histologic grading of the tumors. RESULTS: Contrast enhancement was observed always in anaplastic group (17 /17), in a portion of intermediate-grade group (4/10) but not in low-grade group (0/14). Peritumoral edema was observed infrequently in anaplastic group (4/18) or intermediate-grade group (1/12). Cystic changes (25/46) or calcifications on CT Scans (14/37) were not related with histologic grading. Grossly identifiable hemorrhage was rare in this series (2/46). Among the various imaging features, only tumor enhancement and peritumoral edema were statistically significant for trend test (p<0.05). CONCLUSION: When considering the diagnosis of oligodendrogliomas, the presence of contrast enhancement or peritumoral edema is a helpful features suggesting anaplastic oligodendrogliomas.
Diagnosis ; Edema ; Hemorrhage ; Humans ; Loma ; Magnetic Resonance Imaging ; Oligodendroglioma* ; Retrospective Studies ; Tomography, X-Ray Computed

Optic pits are congenital craterlike holes or indentation in the surface of the optic disc. They are oval in shape and located in the inferior temporal quadrant of the optic disc. The authors experienced a case of congenital optic pit of the left eye of 18 year old male-patient. Fluorescein angiography showed hypofluorescence of the pit in early arteriovenous phase, becomming hyperfluorescence in the late phase. Ophthalmoscopic view of the diseased eye showed no abnormality of macular area. There was no visual field defect except the enlarged physiologic blind spot. Here we briefly report a case of congenital optic pit. referring the literature relating to the optic pit.
Adolescent ; Fluorescein Angiography ; Humans ; Optic Disk ; Visual Fields

PURPOSE: To evaluate the chest radiographic findings of rickettsial disease including murine typhus and tsutsugamushi disease in Chunchon. MATERIALS & METHODS: Chest radiographic films of 81 cases diagnosed as rickettsial disease(55 cases of tsutsugamushi disease, 26 cases of murine typhus) by immunofluorescence test were retrospectively analyzed. RESULTS: Main serotypes of Rickettsia tsutsugamushi were Gilllain and Karp. Incidence rate of tsutsugamushi disease was 2.1 times greater than that of murine typhus. Chest radiographs were abnormal in 63.6% of tsutsugamushi disease, and in 30.8% of murine typhus. Radiographic findings were Kerly's B line, reticu-Ionodular densities, hilar enlargement, pleural effusion, and splenomegaly in both entities, but pulmonary consolidation was only found in tsutsugamushi disease. The patients with the abnormal radiographic findings were statistically well correlated with cardiomegaly(p<0.01) and azygos engorgement(p<0.05), as compared to the patients with normal radiographic findings. CONCLUSION: Radiographic findings of both murine typhus and tsutsugamushi disease were interstitial pattern. But the chest radiographs in patients with tsutsugamushi disease showed more severe pattern with higher rate of abnormality.
Fluorescent Antibody Technique ; Gangwon-do* ; Humans ; Incidence ; Orientia tsutsugamushi ; Pleural Effusion ; Radiography, Thoracic* ; Retrospective Studies ; Scrub Typhus* ; Splenomegaly ; Thorax* ; Typhus, Endemic Flea-Borne*

A statistical observation was made on 325 in-patients with age distribution, disease entities and operative procedures in the Department of Urology, Seoul Red Cross Hospital, during the period from January 1st 1977 to December 31st 1979.
Age Distribution ; Red Cross ; Seoul ; Surgical Procedures, Operative ; Urology

Authors experienced a case of torsion of spermatic cord recently and reviewed the literatures. The patient was a 33 year-old male with chief complaints of sudden onset on left scrotal swelling and testicular pain. Physical examination was not significant except positive Prehn`s sign on the involving side of testicle. Under the diagnosis of torsion of spermatic cord, he was performed of left orchiectomy and the opposite side orchiopexy.
Adult ; Diagnosis ; Humans ; Male ; Orchiectomy ; Orchiopexy ; Physical Examination ; Spermatic Cord Torsion ; Spermatic Cord* ; Testis

A statistical observation was made on 371 in-patients with age distribution, disease entities and operative procedures in the department of Urology, Seoul Red Cross Hospital, during the period from January 1st, 1974 to December 31st, 1976.
Age Distribution ; Red Cross ; Seoul ; Surgical Procedures, Operative ; Urology

Most chordomas show extradural extension and bone destruction. A 32-year-old man presented with neck pain and progressive paraparesis. He had been diagnosed a clival chordoma and underwent an operation seven years ago. Radiological studies revealed that the tumor was recurred in a retroclival area and invaded into intradural region. We removed the tumor by two staged operations. After surgery, satisfactory resluts were achieved.
Adult ; Chordoma* ; Cranial Fossa, Posterior ; Humans ; Neck Pain ; Paraparesis

Most chordomas show extradural extension and bone destruction. A 32-year-old man presented with neck pain and progressive paraparesis. He had been diagnosed a clival chordoma and underwent an operation seven years ago. Radiological studies revealed that the tumor was recurred in a retroclival area and invaded into intradural region. We removed the tumor by two staged operations. After surgery, satisfactory resluts were achieved.
Adult ; Chordoma* ; Cranial Fossa, Posterior ; Humans ; Neck Pain ; Paraparesis