The present study was performed to observe tegumental ultrastructure of Echinoparyphium recurvatum according to developmental stages. Worms (1, 3, 5 and 15-day old) were recovered from chicks experimentally infected with metacercariae from Radix auricularia coreana. One-day old worms were elongated and ventrally concave, and covered with peg-like tegumental spines except the adjecent areas of the head crown and excretory pore. Type I sensory papillae were distributed on the lip of the oral sucker, and grouped ciliated papillae were around the oral sucker. Peg-like tegumental spines were densely distributed on the anterior surface of the ventral sucker level. The ventral sucker had an aspinous tegument and no sensory papillae. Tegumental spines on the posterior surface of the ventral sucker level were sparsely distributed and disappeared posteriorly. In 3 and 5-day old worms, the tegument around the oral sucker was aspinose and wrinkled concentrically. The ventral sucker had a wrinkled tegument and many bulbous papillae. Type I sensory papillae were distributed between the bulbous papillae. Tegumental spines were spade-shaped with a terminal tip. A total of 45 collar spines including 4 end group ones on both ventral corners was alternately arranged in 2 rows. The 15-day old worms were very stout and their tegumental spines were tongue-shaped without a terminal tip. From the above results, it is confirmed that the surface ultrastructure of E. recurvatum was generally similar to that of other echinostomatid flukes. However, some features, i.e., morphological change of tegumental spines and appearence of sensory papillae on the ventral sucker according to development, and number, shape and arrangement of collar spines, were characteristic, which may be of taxonomic and bioecological significance.
Animals ; Chickens ; Echinostomatidae/anatomy & histology/growth & development/*ultrastructure ; Life Cycle Stages ; Lymnaea/parasitology ; Microscopy, Electron, Scanning

This paper presents the result and statistical analysis of the experiment, in which selective anterior or posterior rhizotomy were carried out under microscopic surgery. The materials used for the experiment were 48 young rabbits, and they were divided into four groups. The group I, which was used as control, was subjected to lower dorsal bilateral laminectomies with dural incision, the group II to laminectomies with three right posterior rhizotomies, the group III to laminectomies with three right anterior rhizotomies, and the group IV to laminectomies with three right anterior and posterior rhizotomies. Scoliosis was induced in group Il, Ill and IV. There was no significant statistical difference in the degrees of curvatures among these three groups. The convexity of the curvature faced to the side of the divided roots. In group III and IV, scoliotic curvatures were obvious within two weeks, but there were no considerable changes thereafter. In group Il, the curves progressed slowly up to the 12th week. They were statistically significant at the 4th week and increased continuously thereafter. The histological findings in the group III and IV showed denervation atrophy of the paravertebral muscles at the apex of the curvature, but there was little or no muscle atrophy in the group I and II. We came to a conclusion from the experimental results that scoliosis may be induced not only by anterior root paralysis but also by selective posterior root paralysis.
Atrophy ; Denervation ; Laminectomy ; Muscles ; Muscular Atrophy ; Paralysis ; Rabbits ; Rhizotomy ; Scoliosis

Various kinds of bone cements mixed with antibiotics have been widely used for treatment and prevention of infections, especially combined with bone defects. But bone cements have some disadvantages in that they are rather expensive and capable of incurring some complications such ss fibrosis of surrounding soft tissue or local erosion of bone, and furthermore, they must be removed after infection is controlled for bone graft to fill up the defects because they do not have properties of osteoconduction or osteoinduction. So we have come to the idea of using theoretically advantageous plaster of paris to take place of bone cements, and performed in-vitro experiment upon the effectiveness of plaster of paris pellets containing antibiotics, then obtained good results comparable to those from many experimental studies using bone cements. By this, we think that it would be possible in the future to treat and prevent infections supervening bone defects with plaster of paris mixed up with antibiotics. The results are as follows : 1. Sustained release of large amount of antibiotics from plaster of paris enough to exert inhibitory activity on abcterial growth, and there was a direct relationship between concentrations of eluted antibiotics and diameters of inhibitory zones. 2. Tobramycin was capable of inhibiting the growth of S. aureus, E. coli, and Ps. aeruginosa for 7 days at maximum. 3. Cephradine inhibited the growth of S. aureus and E. coli but did not affect that of Ps. aeruginosa. 4. The maximum antibacterial activity wss reached within first 24 hours from the start of elution of antibiotics from plaster of paris.
Anti-Bacterial Agents ; Bone Cements ; Bone Regeneration ; Calcium Sulfate ; Cephradine ; Fibrosis ; Tobramycin ; Transplants

Attention has been drawn to the possible deliterious effects on operating theatre personnel of breathing in an atmosphere polluted with anaesthetic vapour, in particular, halothane. Whether or not the relation of these effects of anaesthetic vapours has been adequately proved, there is unlikely to be any disagreement that pollution of theatre air with anaesthetic is undesirable. Comparable atmospheric pollution with halothane in the same theatre was studied with and without use of halothane absorber "Aldasorber". The theatre had no device for reducing air pollution. Anaesthetic exhaust fases were drained to the ground. An anaesthetic machine in a semiclosed circle with carbon dioxide absorber was used throughout the anaesthesia. Anaesthesia was maintained with halothane l.0% and 50% oxygen in nitrous oxide, free gas flow rate were oxygen l.5 liter/min and nitrous oxide 1.5 liter/min, Halothane concentrations at various sites of the operating theatre were studied using the method of gas chromatography. 1) Halothane concentrations in the atmosphere of the operating theatre were 0.11 +/-0.07 ppm without halothane absorber and 0.13 +/-0.14 ppm with halothane absorber at the level of 115cm above the operating theatre floor before anaesthesia. 2) Halothane concentrations in the atmosphere of the operating theatre were 7.50 +/-1.32ppm without halothane absorber and 2.82 +/-0.93 ppm with halothsne absorber at the level of 115cm above the operating theatre floor after 3 hours of anesthesia. 3) Comparing this data it was concluded that the concentration of halothane vapour in the operating theatre air after 3 hours of anesthesis could be reduced by 65% W1th halothane absorber Aldasorber.
Air Pollution ; Anesthesia ; Atmosphere ; Carbon Dioxide ; Chromatography, Gas ; Halothane* ; Nitrous Oxide ; Operating Rooms* ; Oxygen ; Respiration

A clinical observation was made on 5 cases of primary ureteral tumors admitted to the Department of Urology, Presbyterian Medical Center during the period from August, 1970 through March, 1978. Clinical and radiographic findings are summarized below: 1. Among 5 cases of primary ureteral tumors, 4 cases in male, 1 case in female. 2. The range in age was from 58 to 75 years, average 66 years. 3. Duration of symptoms varied from 1 day to 1 year, common symptoms are hematuria and flank pain (1 case). 4. The side of lesion: left 3 cases , right 2 cases. 5. All tumors are located in the lower third of ureter. 6. The characteristic urographic and cystoscopic findings are as follows ; Non-visualizing kidney disclosed by intravenous pyelogram in 3 cases, hydroureteronephrosis in 2 cases. filling defect of ureter in 2 cases. The appearance of tumor in the orifice on cystoscopy in 2 cases. 7. Nephroureterectomy with excision of a cuff of the bladder was performed in all cases.
Cystoscopy ; Female ; Flank Pain ; Hematuria ; Humans ; Kidney ; Male ; Protestantism ; Ureter* ; Urinary Bladder ; Urology

No abstract available.
Colorectal Neoplasms*

PURPOSE: To evaluate the clinical usefulness of PAP in staging and monitoring of patient with prostate cancer, we performed a comparative study with PSA, retrospectively. METHODS: We evaluated 72 patients with prostate cancer. Of these patients 11 had stage A, 6 stage B, 10 stage C, 5 stage D1 and 40 stage D2 prostate cancer. Serum PAP level was measured in all 72 patients and serum PSA level was measured concomitantly in 42 patients. RESULTS: The mean initial PAP value was 13.40+/- 7.00 U/L. But only 40 (55.6%) had elevated PAP value above 1.5U/L at presentation. Of 55 advanced cases (stage C, D), 39 (76.9%) had elevated PAP values. Of the 42 patients, who underwent longitudinal PSA assessment, the mean initial PSA value was 178.0 +/- 33.3 ng/ml. Forty (95.2%) had elevated PSA value above 4 ng/ml at presentation. Of 41 advanced cases (stage C, D1, D2), 33 (80.5%) exceeded 50 ng/ml. None of the patient had elevated PAP value with normal PSA value at presentation. Among 42 patients, who had followed with longitudinal serum PSA and PAP, progression of the disease to the bone, lung, and rectum occurred in 26 patients; in all PSA was the first indicator of progression and in none of them PAP anticipated PSA elevation. CONCLUSIONS: Although PAP value usually reflects advanced prostate cancer (70.9%), serum PSA also reflects it (80.5%). Serum PSA monitoring is superior to serum PAP monitoring in predicting disease progression. The use of PSA and PAP jointly to stage and monitor prostate cancer did not appear to enhance the clinical utility over that of PSA alone.
Acid Phosphatase* ; Disease Progression ; Humans ; Lung ; Prostate* ; Prostate-Specific Antigen* ; Prostatic Neoplasms* ; Rectum ; Retrospective Studies

BACKGROUND: Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist with analgesic properties. This study was undertaken to evaluate the potential utility of epidural ketamine combined with meperidine and bupivacaine for postoperative patient-controlled epidural analgesia (PCEA) after cesarean section. METHODS: Forty-five patients received epidural catheterization in the L3-4 intervetebral space and underwent cesarean section under epidural anesthesia. In the recovery room, these patients were randomly allocated to 3 groups; group I (control; n = 15) received 1 mg/ml bupivacaine and 1 mg/ml meperidine, group II (n = 15) received 1 mg/ml bupivacaine and 1 mg/ml meperidine with 0.25 mg/ml ketamine, group III (n = 14) received 1 mg/ml bupivacaine and 1 mg/ml meperidine with 0.75 mg/ml ketamine using a PCEA device for postoperative pain control. The analgesic effects and PCEA consumption were assessed at 6, and 24 hours after surgery. Side effects were also evaluated. RESULTS: There were no statistically significant differences in the visual analogue scale for pain, the consumption of the analgesics and side effects among the groups. CONCLUSIONS: Epidural ketamine combined with bupivacaine and meperidine did not improve postoperative analgesia, nor did it reduce consumption of the analgesics and side effects.
Analgesia ; Analgesia, Epidural ; Analgesics ; Anesthesia, Epidural ; Bupivacaine* ; Catheterization ; Catheters ; Cesarean Section* ; Female ; Humans ; Ketamine* ; Meperidine* ; N-Methylaspartate ; Pain, Postoperative* ; Pregnancy ; Recovery Room

No abstract available.
Neurofibromatoses* ; Scoliosis*

No abstract available.
Osteoblasts*