1.3 Cases Report of Myositis Ossificans Progressiva
Joon Young KIM ; Choo Bong CHUN ; Woo Suck WHANG ; Chul Yong CHUNG ; Young Joe KIM
The Journal of the Korean Orthopaedic Association 1972;7(2):228-234
Myositis Ossificans progressiva is a very rare disease and not more than five cases have been reported in this country. The symptoms usually appear before the age of six and no case has ever been reported in medical literature in which patient is older than the age of twenty. This author reports here that a 52 years old male was diagnoed as a myositis ossificans progressiva. The patient developed his symptoms when he was lynched by a club during the Korean conflict at the Korean conflict at the age of thirty. Another interesting fact is that is that his daughter has also developed similar symptoms which appeared following an accident when she was run over by an angry cow at the age of six.
Humans
;
Korean War
;
Male
;
Myositis Ossificans
;
Myositis
;
Nuclear Family
;
Rare Diseases
2.The effect of ultraviolet-B irradiation on the cardiac allograft in mice.
Jong Seo LEE ; Hae Myung CHUN ; Eung Kook KIM ; Sang Yong CHOO
Journal of the Korean Surgical Society 1991;41(1):1-8
No abstract available.
Allografts*
;
Animals
;
Mice*
3.Two Cases of Atopic Dermatitis Developing Ocular Complication and Immunological Disturbance.
Chun Wook PARK ; Sung Woo CHOI ; Eun Hee CHOO ; Ik Jun KO ; Hyung Ok KIM ; Chung Won KIM
Korean Journal of Dermatology 1984;22(6):631-634
The relation of atopic dermatitis to various manifestations of ocular disease has been documented in the dermatologic literature. Several lines of evidence suggest that patients with atopic dermatitis have defective ceil-mediated immunity and decreased cellular hypersensitivity. In this paper, we presented two cases of atopic dermatitis developing ocular complication and abnormal immune response in vivo and in vitro during the course of atopic dermatitis.
Dermatitis, Atopic*
;
Humans
;
Hypersensitivity
4.A Case of Acute Lymphocytic Leukemia Successfully Treated with Allogeneic Bone Marrow Transplantaion.
In Kyung SUNG ; Byung Churl LEE ; Kyong Su LEE ; Du Bong LEE ; Chong Won PARK ; Chun Choo KIM ; Dong Jip KIM
Journal of the Korean Pediatric Society 1985;28(8):805-811
No abstract available.
Bone Marrow*
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
5.Effects of ondansertron in the prevention of nausea and vomiting associated with chemotherapy in acute myelocytic leukemia.
Woo Sung MIN ; Jong Youl JIN ; Chi Wha HAN ; Chong Won PARK ; Chun Choo KIM ; Dong Jip KIM
Journal of the Korean Cancer Association 1992;24(2):288-292
No abstract available.
Drug Therapy*
;
Leukemia, Myeloid, Acute*
;
Nausea*
;
Vomiting*
6.Immune Tolerance Effect of Immature Dendritic Cells Cultured Using Low-dose GM-CSF.
Jeong A KIM ; Sungyoul HONG ; Yun Seok CHOI ; Chun Choo KIM
Korean Journal of Hematology 2003;38(2):100-107
BACKGROUND: Dendritic cells induce tolerance in the immature state besides the function of antigen presenting cells in the mature state. Using this effect, it will be overcome the rejection in organ transplantation. In this research we are to confirm the tolerance effect and induction mechanism in immature dendritic cell cultured with low-dose GM-CSF. METHODS: Dendritic cells were cultured from BALB/c (H-2d) bone marrow cells in the low concentration of GM-CSF (5U/mL, GM(lo)DC) for 10 days. The phenotype and functional properties of these GM(lo)DC were compared to those of standard BM-DC cultures generated in the high concentrations of GM-CSF (200U/mL) with lipopolysaccharide (GM(hi)DC). RESULTS: Compare to mature DC, GM(lo)DC expressed the low level of CD80 and CD86 and these cells were weak stimulators of allogeneic T cell responses by mixed lymphocyte reaction. The administration of GM(lo)DC prolonged allogeneic skin graft survival (median survival time 11.3+/-1.2 days, compared with 6.6+/-0.8 days in nontreated controls). The effects of these cells were donor specific but couldn't be sustained for a long period. CONCLUSIONS: GM(lo)DC were phenotypically immature and they didn't induce allogeneic T cell responses compared with GM(hi)DC in vitro. It is suggested that the less expression of costimulatory molecule in GM(lo)DC induce the tolerance effect.
Antigen-Presenting Cells
;
Bone Marrow Cells
;
Dendritic Cells*
;
Graft Survival
;
Granulocyte-Macrophage Colony-Stimulating Factor*
;
Humans
;
Immune Tolerance*
;
Lymphocyte Culture Test, Mixed
;
Organ Transplantation
;
Phenotype
;
Skin
;
Tissue Donors
;
Transplants
7.Differential Diagnosis of Myelodysplastic Syndrome and Aplastic Anemia using MRI.
Chun Choo KIM ; Dong Wook KIM ; Kyung Sub SHINN ; Ki Tae KIM ; Jae Mun LEE ; Seung Eun JUNG ; Jung Mi PARK ; Chun Yul KIM
Journal of the Korean Radiological Society 1995;32(4):625-631
PURPOSE: To assess the patterns of myelodysplastic syndrome(MDS) and aplastic anemia(AA) on MRI of the spinal bone marrow and to find the differential points between the two groups. MATERIALS AND METHODS: Fourteen patients with MDS(n=7) and AA(n=7) were studied using magnetic resonance imaging. Sagittal images from the lower thoracic and lumbar vertebral marrow were evaluated on Tl-weighted and STIR images. Five distinct patterns of signal intensity of the Tl-weighted and STIR images were classified. T1 and T2 relaxation times and T1 marrow/fat signal intensity ratio were measured and analyzed (t-test). The cellularity of bone marrow was evaluated on histologic slides. RESULTS: MDS showed homogeneously low signal intensity on T1WI and high signal intensity on STIR image, indicating hypercellular marrow, whereas AA showed relative high signal intensity on T1WI and low signal intensity on STIR image, representing fatty marrow. T1 and T2 relaxation time(T1 for MDS=750.26msec +/- 177.50, T1 for AA= 413.21 msec +/- 167.39 (p<0.000), T2 for MDS=91.86 msec +/- 14.16, T2 for AA=81.44msec +/- 15.31 (p< 0.001) and T1 marrow/fat signal intensity ratio(0.22 +/- 0.048 in MDS, 0.30 +/- 0.083 in AA(p<0.000)) revealed statistically significant difference between the two groups. CONCLUSION: Although the marrow aspiration and needle biopsy are mandatory in hematologic disease for diagnosis, there are limited in assessing the change of total marrow mass. Therefore MRI of bone marrow might be useful in distinguishing MDS from AA because of its ability of representation of total marrow mass.
Anemia, Aplastic*
;
Biopsy, Needle
;
Bone Marrow
;
Diagnosis
;
Diagnosis, Differential*
;
Hematologic Diseases
;
Humans
;
Magnetic Resonance Imaging*
;
Myelodysplastic Syndromes*
;
Relaxation
8.Differential Diagnosis of Myelodysplastic Syndrome and Aplastic Anemia using MRI.
Chun Choo KIM ; Dong Wook KIM ; Kyung Sub SHINN ; Ki Tae KIM ; Jae Mun LEE ; Seung Eun JUNG ; Jung Mi PARK ; Chun Yul KIM
Journal of the Korean Radiological Society 1995;32(4):625-631
PURPOSE: To assess the patterns of myelodysplastic syndrome(MDS) and aplastic anemia(AA) on MRI of the spinal bone marrow and to find the differential points between the two groups. MATERIALS AND METHODS: Fourteen patients with MDS(n=7) and AA(n=7) were studied using magnetic resonance imaging. Sagittal images from the lower thoracic and lumbar vertebral marrow were evaluated on Tl-weighted and STIR images. Five distinct patterns of signal intensity of the Tl-weighted and STIR images were classified. T1 and T2 relaxation times and T1 marrow/fat signal intensity ratio were measured and analyzed (t-test). The cellularity of bone marrow was evaluated on histologic slides. RESULTS: MDS showed homogeneously low signal intensity on T1WI and high signal intensity on STIR image, indicating hypercellular marrow, whereas AA showed relative high signal intensity on T1WI and low signal intensity on STIR image, representing fatty marrow. T1 and T2 relaxation time(T1 for MDS=750.26msec +/- 177.50, T1 for AA= 413.21 msec +/- 167.39 (p<0.000), T2 for MDS=91.86 msec +/- 14.16, T2 for AA=81.44msec +/- 15.31 (p< 0.001) and T1 marrow/fat signal intensity ratio(0.22 +/- 0.048 in MDS, 0.30 +/- 0.083 in AA(p<0.000)) revealed statistically significant difference between the two groups. CONCLUSION: Although the marrow aspiration and needle biopsy are mandatory in hematologic disease for diagnosis, there are limited in assessing the change of total marrow mass. Therefore MRI of bone marrow might be useful in distinguishing MDS from AA because of its ability of representation of total marrow mass.
Anemia, Aplastic*
;
Biopsy, Needle
;
Bone Marrow
;
Diagnosis
;
Diagnosis, Differential*
;
Hematologic Diseases
;
Humans
;
Magnetic Resonance Imaging*
;
Myelodysplastic Syndromes*
;
Relaxation
9.Clinical study on congenital preauricular fistula.
Sang Keun SHIN ; Ki Yeub SEUL ; Hyung Joo RHEE ; Kil Dong KIM ; Jin Shin CHOO ; Young Chun KANG
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):909-915
No abstract available.
Fistula*
10.A Case of Disseminated Mucormycosis after Allogenic Bone Marrow Transplantation.
Sun Hwa KIM ; Ki Bum KIM ; Young Mi CHOO ; Woo Im CHANG ; Yang Soo KIM ; Dong Gun LEE ; Jung Hyun CHOI ; Wan Shik SHIN ; Chang Ki MIN ; Chun Choo KIM
Korean Journal of Infectious Diseases 2000;32(1):73-77
Disseminated mucormycosis is a rare fungal infectious disease with a high mortality rate and is infrequently diagnosed ante mortem. It is most frequently seen in immunocompromised hosts such as diabetes mellitus, hematologic malignancies, or in the long-term use of steroids or chemotherapeutic agents. Tissue invasion by the hyphae of mucormycosis must be seen microscopically to establish the diagnosis. Treatment consists of correction of the predisposing condition, surgical debridement, and amphotericin-B therapy. A 35-year-old man was admitted through the emergency room due to fever and the right flank pain. He had received an allogenic bone marrow transplantation eight months ago and had been medicated with prednisolone and cyclosporine since the procedure. He was diagnosed with disseminated mucormycosis that involved the spleen, right kidney, and right lung. He is being successfully treated with amphotericin B, flucytosine, and liposomal amphotericin B.
Adult
;
Amphotericin B
;
Ants
;
Bone Marrow Transplantation*
;
Bone Marrow*
;
Communicable Diseases
;
Cyclosporine
;
Debridement
;
Diabetes Mellitus
;
Diagnosis
;
Emergency Service, Hospital
;
Fever
;
Flank Pain
;
Flucytosine
;
Hematologic Neoplasms
;
Humans
;
Hyphae
;
Immunocompromised Host
;
Kidney
;
Lung
;
Mortality
;
Mucormycosis*
;
Prednisolone
;
Spleen
;
Steroids