Observation on the effect of whole rice and whole wheat as sole food on the growth of young rats are furtherly made. The results showed that both whole rice and whole wheat showed no significant difference in the growth of young albino rats, but the difference between the rice group and rice plus leafy vegetable and egg group and that between the wheat group and wheat plus leafy vegetable and egg group are highly significant. Addition, of small amount of vegetable and egg alternatively as supplementary food significantly enhanced the nutritive value, in terms of growth effect, of both whole rice and whole wheat.

Objective To compare the amplitude and latency of event-related potential P300 be-tween impulsive and predictive violent criminals. Methods Twenty impulsive violent criminals and twenty predictive violent criminals were recruited from one prison in Wenzhou city. Twenty matched healthy controls from community were recruited. Criminals in both groups were excluded from violent crimes caused by mental disorders by judicial psychiatrists using DSM-IV axis I disorder clinical stereotyped interviews. Nicolet Bravo Brain Evoked Potentiometer (produced by Nicolet Company,USA) was used to detect the P300 components of the above three groups of subjects. Eysenck Impulsiveness Scale was used to assess the impulsiveness. Results The P300 amplitude of impulsive violent criminals was smaller than that of predictive violent crimi-nals( (4. 52±1. 14)μV vs (13. 88±2. 06)μV,t=17. 779,P<0. 01),but there was no significant difference of the P300 amplitude between predictive violent criminals and community enrolled controls ((13. 88±2. 06) μV vs (14. 01±1. 86)μV,t=0. 209,P=0. 835). The impulsivity scale score of impulsive violent criminals was highly negatively correlated with the amplitude of P300 (r=-0. 812,P=0. 002). There were no signifi-cant differences in the latency of P300 among impulsive violent criminals,predictive violent criminals and community enrolled controls group. And there was no significant correlation between the latency of P300 and the score of impulsivity scale (P>0. 05). Conclusion The P300 amplitude can aid in the differential diag-nosis of violent criminals with and without impulsive behavior.

Objective To examine the effects of participating in Balint group ( PBG) for reducing occupational burnout among primary care physicians (PCPs). Methods In this randomized controlled trial, 240 PCPs were randomly assigned to PBG (n=70) and control group (n=240) in propotion of 1 ∶ 2. Sub-jects of PBG received Balint group intervention for one year,while control group received natural observation. Maslach Burnout Inventory ( MBI) was used to assess the severity of occupational burnout. Results At baseline all three subscales of MBI had no significant difference between PBG and cotrol group(P>0. 05). After the intervention,PBG had statistically lower subscale scores in emotional exhaustion ((20. 1±8. 3) vs (22. 6±8. 7),t=1. 993,P=0. 048) and depersonalization (( 6. 8± 4. 9) vs ( 10. 8 ± 5. 2),t=5. 355,P<0. 001) than the control group, while had statistically higher score in personal accomplishment subscale ((38. 3±7. 5) vs (34. 6±7. 7),t=3. 311,P=0. 001) than the control group. Conclusions PBG is effective in reducing occupational burnout among PCPs.

Objective: To analyze the clinical characteristics of hand, foot and mouth disease (HFMD) caused by coxsackievirus A6 (CV-A6) in different age groups. Methods: From January 2015 to December 2017, throat swabs were collected from children with or suspected of having HFMD then quantitative real-time PCR was performed to detect enterovirus nucleic acid. HFMD cases caused by CV-A6 were divided into different groups according to age for comparison. Results: In total, there were 467 cases of HFMD caused by CV-A6 with the age ranging from 3 months to 16 years. There were 273 cases in the infants and young children group (< 3 years old), 131 cases in the pre-school group (3-6 years old), and 63 cases in the school-age group (> 6 years old). The peak incidence was found between May and November.Fever was the common symptom, and the rate of fever in infant group was the highest (220/273, 80.5%); The proportion of cases with leucocyte elevation in the infant group was the highest (127/273, 46.5%) than that in the school-age group (17/63, 27.0%) with a statistical significance. The skin erythra of the HFMD caused by CV-A6 were diverse in forms. Over two forms of skin erythra accounted for 53.9% (257/476) of all cases, and the cases in the infant group showing more forms of skin erythra (163/273, 59.7%). The oral herpes were mainly distributed in the upper palate and pharyngeal isthmus, but the school age group had the least number of distribution sites (0.89±0.86). The cases in the infant group showed higher incidence of skin rash at the elbow joint (109/273, 39.9%), knee (88/273, 32.6%), thigh (112/273, 41%), buttock (122/273, 44.7%) than the other two groups, However, the school age group showed lower incidence of skin rash in the lower leg (0/63, 0%) and thigh (6/63, 9.5%) than the other two groups. The differences between groups were statistically significant. All cases were cured clinically, no severe cases occurred. Among the 288 cases followed up for 6 months, 33 (33/288, 11.5%) suffered from nail exfoliation. Conclusions Different age groups of HFMD caused by CV-A6 had different clinical manifestations. In the infant group, more cases had fever and the erythra were more diverse in forms and wider in distribution. In addition, the increased leukocytes in routine blood test was also more common in the infant group.