Background: Stomach cancer is the most commonly diagnosed malignant tumor in Korea. Early detection by mass screening very important to increase survival rate of stomach cancer, because the prognosis of early gastric cancer is excellent, and specific symptoms and physical findings are rare with early gastric cancer. Methed: 1865 car manufacturing company employees were examinined by gastrofiberscopy at a dispensary of the company from May 6, l992 to July 13, 1992. Results: 1. Number of cases with normal finding was 1262(67.7%), gastritis 422(22.6%), gastric ulcer 47(2.5%), gasrtric cancer 4(0.2%), duodenitis 39(2.1%), duodenal ulcer 63(3.4%), combined ulcer(gastric & duodenal) 2(0.1%,), post operative state 6(0.3%), and others 4(0.3%) in total 1865 examinees. 2. Of 422 cases with gastritis, cases with superficial gastritis were 171 (9.2%), atrophic gastritis 138(7.4%), erosive gastritis 94(5.0%) and hemorrhagic gastritis 19(1.0%). 3. Of 4 cases with stomach cancer, 1 case was advanced stomach cancer and 3 cases were early gastric cancer(two cases of IIc and one case of IIc+III) by macroscopic classification. Conclusion: Mass screening provides an excellent opportunity to detect gastric cancer in populations without symytoms or with nonspecific symptoms. It should be recommended to undergo screening exam for high risk group of stomach cancer.
Classification ; Duodenal Ulcer ; Duodenitis ; Gastritis ; Gastritis, Atrophic ; Korea ; Mass Screening* ; Prognosis ; Stomach Neoplasms* ; Stomach Ulcer ; Stomach* ; Survival Rate

A retrospective analysis was performed on the 968 cases of fetal or pediatric autopsies over five year period (1990-1994), at the Seoul National University Children's Hospital. Age/mode distribution of cases were artificial abortus(30.6%), spontaneous abortus(12.0%), stillbirth(21.9%), neonates(29%), infants(2.8%) and children(0.9%). Male/female ratio was 1.21. Overall incidence of congenital anomalies was 60.8% and 34.0% of all cases had anomalies involving multiple organ systems. Percentage of cases with any anomaly was 71.6% in artificial abortus, 35.3% in spontaneous abortus, 59% in still births, 65.5% in neonates and 38.9% in infant and children. Common organ systems involved were the cardiovascular system (39.0%), musculoskeletal system (23.6%), nervous system (22.6%), gastrointestinal system (19.9%), and urinary system (14.6%). From these results, we found that the congenital anomalies were most significant diseases of the perinatal period and the cardiovascular anomalies were the most common anomalies of them.
Autopsy* ; Cardiovascular Diseases ; Cardiovascular System ; Child ; Humans ; Incidence ; Infant ; Infant, Newborn ; Musculoskeletal System ; Nervous System ; Parturition ; Perinatal Mortality ; Retrospective Studies ; Seoul*

A retrospective analysis was performed on the 968 cases of fetal or pediatric autopsies over five year period (1990-1994), at the Seoul National University Children's Hospital. Age/mode distribution of cases were artificial abortus(30.6%), spontaneous abortus(12.0%), stillbirth(21.9%), neonates(29%), infants(2.8%) and children(0.9%). Male/female ratio was 1.21. Overall incidence of congenital anomalies was 60.8% and 34.0% of all cases had anomalies involving multiple organ systems. Percentage of cases with any anomaly was 71.6% in artificial abortus, 35.3% in spontaneous abortus, 59% in still births, 65.5% in neonates and 38.9% in infant and children. Common organ systems involved were the cardiovascular system (39.0%), musculoskeletal system (23.6%), nervous system (22.6%), gastrointestinal system (19.9%), and urinary system (14.6%). From these results, we found that the congenital anomalies were most significant diseases of the perinatal period and the cardiovascular anomalies were the most common anomalies of them.
Autopsy* ; Cardiovascular Diseases ; Cardiovascular System ; Child ; Humans ; Incidence ; Infant ; Infant, Newborn ; Musculoskeletal System ; Nervous System ; Parturition ; Perinatal Mortality ; Retrospective Studies ; Seoul*

No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

Among the late postoperative complications of the acute dissection of aorta, the fistula between dilated distal aorta and pulmonary parenchym is so rare that only few case have been reported sporadically. Although the aortopulmonary fistula is one of a fatal condition that needs prompt surgical intervention, with an appropriate management it is well controllable condition. Early diagnosis and urgent surgical intervention is the only way to prevent catastrophic hemorrhage. We experienced a surgical management of aortoplumonary fistula which occurred between upper lobe of the left lung and distal aortic dilatation of previous aortic bypass graft which was performed for Debakey type I acute aortic dissection.
Aorta ; Aortic Aneurysm ; Dilatation ; Early Diagnosis ; Fistula* ; Hemorrhage ; Lung ; Postoperative Complications ; Transplants

Acidosis ; Animals ; Cryosurgery ; Endothelial Cells ; Epigastric Arteries ; Free Tissue Flaps ; Freezing ; Hypovolemia ; Ischemia ; Microsurgery ; Muscle, Smooth ; Proliferating Cell Nuclear Antigen ; Rats ; Rats, Sprague-Dawley ; Regeneration ; Spasm ; Thrombosis ; Veins

No abstract available.
Anemia* ; Bone Marrow Transplantation* ; Bone Marrow*

No abstract available.
Anemia, Aplastic* ; Antilymphocyte Serum* ; Granulocyte-Macrophage Colony-Stimulating Factor* ; Granulocytes* ; Humans*

Seven patients who underwent therapeutic arterial embolization of renal tumors with absolute ethanol are described. In one patient massive life threatening hematuria from the huge angiomyolipoma was successfully controlled by superselective infusion of tumor vessels with absolute ethanol. In five other patients with metastatic renal cell carcinoma intraarterial infusion of absolute ethanol resulted in relief of the troublesome symptoms, hematuria and/or flank pain. In one patient with renal cell caraimma involving inferior vena cava, preoperative ethanol infusion facilitated operative procedure. Usual angiocatheter was used in 5 cases and balloon catheter was used in last 2 cases to prevent potential reflux. A dose of 0.25-0.5ml per kg body weight was injected in a rate o[ 2 ml/sec. Angiography 15 min after ethanol injection revealed complete blockade of the artery in most cases. All patients experienced varying degree of postembolization syndrome but tolerated well. There was no evidence of inadvertent damage of other organs. We found arterial embolization with absolute ethanol is effective and safe method in the management of renal tumors.
Angiography ; Angiomyolipoma ; Arteries ; Body Weight ; Carcinoma, Renal Cell ; Catheters ; Ethanol* ; Flank Pain ; Hematuria ; Humans ; Infusions, Intra-Arterial ; Surgical Procedures, Operative ; Vena Cava, Inferior

OBJECTIVES: APL, which characteristically shows t(15:17), accompanies fatal coagulopathy during remission induction with systemic chemotherapy alone. ATRA, a derivative of vitamin A, can differentiate APL cells as well as HL-60 cells in vitro and induce higher rate of complete remission(CR). Hence, we assessed the effect of ATRA on remission induction and coagulopathy in APL patients. METHODS: (1) 42 patients diagnosed histologically in St. mary's hospital from June 1991 to June 1994 were included. (2) We compared the CR rate, the time required for restoration of derranged coagulation profiles, and the amount of coagulation factors including platelets among the chemotherapy group (control) and ATRA group. RESULTS: 1) There was no difference in CR rate between the control group and ATRA group [84.2%(16 out of 19) vs 87.0%(20 out of 23), p>0.05)] and also no difference between two subgroups of ATRA [ATRA with chemotherapy; 83.3%(10 out of 12) vs ATRA without chemotherapy; 90.9%(10 out of 11), p>0.05] 2) In the ATRA group, the CR rate of newly diagnosed patients was 82.4%(14 out of 17). The first relapsed patients (4) and the second (2) were all achieved CR. 3) The mean duration of coagulopathy, time to normalization of PT, aPTT, FDP, fibrinogen level, was 12.0+/-10.4, 11.1+/-10.2, 16.5+/-9.3, 15.4+/-10.2 days after chemotherapy alone and 4.5+/-4.4, 3.7+/-3.7, 8.9+/-6.1, 8.1+/-6.5 days in the ATRA group(p<0.05). The amount of fresh frozen plasma used in the ATRA group for the purpose of correction of coagulopathy were significantly lower than the control group(p<0.05). The incidence of profound coagulopathy during the remission induction treatment in the ATRA group was significantly lower than the control group[40% (8 out of 20) vs 96.7%(13 out of 15), p
Blood Coagulation Factors ; Drug Therapy ; Fibrinogen ; HL-60 Cells ; Humans ; Incidence ; Leukemia, Promyelocytic, Acute* ; Plasma ; Remission Induction* ; Tretinoin* ; Vitamin A