Background: Stomach cancer is the most commonly diagnosed malignant tumor in Korea. Early detection by mass screening very important to increase survival rate of stomach cancer, because the prognosis of early gastric cancer is excellent, and specific symptoms and physical findings are rare with early gastric cancer. Methed: 1865 car manufacturing company employees were examinined by gastrofiberscopy at a dispensary of the company from May 6, l992 to July 13, 1992. Results: 1. Number of cases with normal finding was 1262(67.7%), gastritis 422(22.6%), gastric ulcer 47(2.5%), gasrtric cancer 4(0.2%), duodenitis 39(2.1%), duodenal ulcer 63(3.4%), combined ulcer(gastric & duodenal) 2(0.1%,), post operative state 6(0.3%), and others 4(0.3%) in total 1865 examinees. 2. Of 422 cases with gastritis, cases with superficial gastritis were 171 (9.2%), atrophic gastritis 138(7.4%), erosive gastritis 94(5.0%) and hemorrhagic gastritis 19(1.0%). 3. Of 4 cases with stomach cancer, 1 case was advanced stomach cancer and 3 cases were early gastric cancer(two cases of IIc and one case of IIc+III) by macroscopic classification. Conclusion: Mass screening provides an excellent opportunity to detect gastric cancer in populations without symytoms or with nonspecific symptoms. It should be recommended to undergo screening exam for high risk group of stomach cancer.
Classification ; Duodenal Ulcer ; Duodenitis ; Gastritis ; Gastritis, Atrophic ; Korea ; Mass Screening* ; Prognosis ; Stomach Neoplasms* ; Stomach Ulcer ; Stomach* ; Survival Rate

A retrospective analysis was performed on the 968 cases of fetal or pediatric autopsies over five year period (1990-1994), at the Seoul National University Children's Hospital. Age/mode distribution of cases were artificial abortus(30.6%), spontaneous abortus(12.0%), stillbirth(21.9%), neonates(29%), infants(2.8%) and children(0.9%). Male/female ratio was 1.21. Overall incidence of congenital anomalies was 60.8% and 34.0% of all cases had anomalies involving multiple organ systems. Percentage of cases with any anomaly was 71.6% in artificial abortus, 35.3% in spontaneous abortus, 59% in still births, 65.5% in neonates and 38.9% in infant and children. Common organ systems involved were the cardiovascular system (39.0%), musculoskeletal system (23.6%), nervous system (22.6%), gastrointestinal system (19.9%), and urinary system (14.6%). From these results, we found that the congenital anomalies were most significant diseases of the perinatal period and the cardiovascular anomalies were the most common anomalies of them.
Autopsy* ; Cardiovascular Diseases ; Cardiovascular System ; Child ; Humans ; Incidence ; Infant ; Infant, Newborn ; Musculoskeletal System ; Nervous System ; Parturition ; Perinatal Mortality ; Retrospective Studies ; Seoul*

A retrospective analysis was performed on the 968 cases of fetal or pediatric autopsies over five year period (1990-1994), at the Seoul National University Children's Hospital. Age/mode distribution of cases were artificial abortus(30.6%), spontaneous abortus(12.0%), stillbirth(21.9%), neonates(29%), infants(2.8%) and children(0.9%). Male/female ratio was 1.21. Overall incidence of congenital anomalies was 60.8% and 34.0% of all cases had anomalies involving multiple organ systems. Percentage of cases with any anomaly was 71.6% in artificial abortus, 35.3% in spontaneous abortus, 59% in still births, 65.5% in neonates and 38.9% in infant and children. Common organ systems involved were the cardiovascular system (39.0%), musculoskeletal system (23.6%), nervous system (22.6%), gastrointestinal system (19.9%), and urinary system (14.6%). From these results, we found that the congenital anomalies were most significant diseases of the perinatal period and the cardiovascular anomalies were the most common anomalies of them.
Autopsy* ; Cardiovascular Diseases ; Cardiovascular System ; Child ; Humans ; Incidence ; Infant ; Infant, Newborn ; Musculoskeletal System ; Nervous System ; Parturition ; Perinatal Mortality ; Retrospective Studies ; Seoul*

No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

Among the late postoperative complications of the acute dissection of aorta, the fistula between dilated distal aorta and pulmonary parenchym is so rare that only few case have been reported sporadically. Although the aortopulmonary fistula is one of a fatal condition that needs prompt surgical intervention, with an appropriate management it is well controllable condition. Early diagnosis and urgent surgical intervention is the only way to prevent catastrophic hemorrhage. We experienced a surgical management of aortoplumonary fistula which occurred between upper lobe of the left lung and distal aortic dilatation of previous aortic bypass graft which was performed for Debakey type I acute aortic dissection.
Aorta ; Aortic Aneurysm ; Dilatation ; Early Diagnosis ; Fistula* ; Hemorrhage ; Lung ; Postoperative Complications ; Transplants

Acidosis ; Animals ; Cryosurgery ; Endothelial Cells ; Epigastric Arteries ; Free Tissue Flaps ; Freezing ; Hypovolemia ; Ischemia ; Microsurgery ; Muscle, Smooth ; Proliferating Cell Nuclear Antigen ; Rats ; Rats, Sprague-Dawley ; Regeneration ; Spasm ; Thrombosis ; Veins

No abstract available.
Anemia* ; Bone Marrow Transplantation* ; Bone Marrow*

No abstract available.
Anemia, Aplastic* ; Antilymphocyte Serum* ; Granulocyte-Macrophage Colony-Stimulating Factor* ; Granulocytes* ; Humans*

The common arterial trunk is a congenital cardiovascular malformation in which one arterial trunk gives origin to the aortic arch, pulmonary and coronary arteries. Other cardiovascular malformations are often associated, such as ventricular septal defect, aortic arch interruption, patent arterial duct and so on. During the early period of life, the persistence of the increased pulmonary arteriolar resistance results in cyanosis. As the pulmonary vascular resistance decreases, the cyanosis disappears but signs of congestive heart failure become the main problems. We report five cases of common arterial trunk that was confirmed by autopsy at Chungnam National University Hospital, Seoul National University Hospital, and Yonsei University Severance Hospital between 1983 and 1995. The ages of these patients at autopsy were 8-28 days and four of them were male. Pulmonary arteries arose as a pulmonary trunk in two cases but three cases showed two arteries arising separately from the posterior wall of the common trunk. The type of ventricular septal defect was juxtatruncal in every case. All five cases had three leaflet truncal valves but three cases showed dysplasia of the leaflets. Interruption of aortic arch was associated in two cases. The cause of death was renal failure in two cases, cardiac failure after corrective surgery in two cases, and pulmonary edema and failure in one case.

BACKGROUND: Aloe vera has been used for medical purposes since antiquity, so it has been known as the healing plant or silent healer. It has been claimed that aloe has several important therapeutic properties including promotion of wound healing, thermal injury healing, anti-inflammation and immunomodulation. Using these effects, it has become an ingredient in a wide variety of cosmetic products including night creams, soaps, shampoos, suntan lotions, and cleansers. OBJECT: In order to investigate the anti-irritant effect of aloe vera we measured transepidermal water loss (TEWL) and erythema index (E-index) after performing a patch test using sodium lauryl sulfate (SLS) and aloe vera we then compared the extent of damaging effect on the skin barriers and the difference of the recovery process in each case. METHODS: Fifteen volunteers, all over 18 years of age, who hadn't had past or present history of atopic dermatitis and other eczemas, were tested in this study. SLS was dissolved in distilled water to the concentration of 1% and aloe vera gel was dissolved in distilled water to the concentrations of 10, 20, 50, and 100%. Then we mixed 1% SLS solution and each concentration of aloe vera solution with the ratio 1: 1. Each solution was applied to marked sites of both volar aspect of the forearm at random, for 24 hours, using large Finn chamber with filter paper. TEWL and E-index were measured before test (BL) and at 30 minutes (D0), 1st day (D1), 2nd day (D2), 1st week (W1), 2nd week (W2), and 3rd week (W3) after removal of the patches. RESULTS: TEWL after removing a patch of 0.5% SLS was higher than that of 100% aloe vera mixed with 1% SLS. In addition, TEWL after removing a patch of 0.5% SLS and 100% aloe vera patch mixed with 1% SLS were higher than that of 100% aloe vera. E-index after removing a patch of 0.5% SLS was higher than that of 50% aloe vera mixed with 1% SLS, 100% aloe vera mixed with 1% SLS, and 100% aloe vera. CONCLUSION: We have come to know that aloe vera has an effect in the recovery of skin barriers and erythema induced by irritant such as SLS. However, it only happens when the gel of aloe vera has a high concentration.
Aloe* ; Dermatitis, Atopic ; Eczema ; Erythema ; Forearm ; Immunomodulation ; Patch Tests ; Plants, Medicinal ; Skin ; Soaps ; Sodium Dodecyl Sulfate* ; Sodium* ; Suntan ; Volunteers ; Water ; Wound Healing