No abstract available.
Porphyromonas gingivalis* ; Porphyromonas* ; Virulence*

No abstract available.
Porphyromonas gingivalis* ; Porphyromonas* ; Virulence*

In 1985, Stein et al, indentified an anaplastic large-cell malignant lymphoma that was distinctive because of the diffuse dermal infiltration of pleomorphic large lymphocytes, sinus growth pattern, and reactivity with the monoclonal antibody Ki-1(CD30). The clinical feature; distinguishing anaplastic large-cell Ki-1 lymphoma include a young median age, frequent peripheral adenopathy with sparing of the mediastinum, and extranodal disease with skin the most common sitc of involvement. We report a case of Ki-1 postive large-cell lymphoma in a 74-year-old male patient who presented with multiple ulcerated nodules on the right shin area.
Aged ; Humans ; Lymphocytes ; Lymphoma* ; Lymphoma, Large-Cell, Anaplastic ; Male ; Mediastinum ; Skin ; Ulcer

We evaluated the therapeutic effect of potassium iodide in fourteen patients with erythema nodosum. The results were as follows: 1) All patients were given a saturated solution of potassium iodide, 600 to 900 mg orall y a day for 3 days to 5 weeks. 2) Three patients were observed initial days, two patients within 9 days. 3) There were no correlations between therapeutic effect of potassium iodide. 4) Specific side effects were not found during the treatment with potassium iodide.
Erythema Nodosum* ; Erythema* ; Humans ; Potassium Iodide* ; Potassium*

We examined the causes of delaying or cancellation of the elective surgery at Seoul National University Children's Hospital. The total numbers of pediatric patient for the elective surgery during September 1, 1994, to November 30, 1994, were 1287 and that of delaying or cancellation of surgery were 135. The fraction of medical causes of delaying of the elective surgery was 62.2%, and that of non-medical causes of the elective surgery was 36.3%, and 1.5% was unknown. The single most frequent cause was upper respiratory infection, 42.2% of total delays, and the second was that patient had not be admitted as 16.3%o of total delays. The third frequent cause was no indication for surgery as 6.7%, the fourths were fever and inadequate preparation for surgery (5.2%), and the sixth was that the patient had refused to give an informed consent (3.7%), etc.
Fever ; Humans ; Informed Consent ; Seoul

We recently noticed four cases of Vibrio(V.) vulnificus infection from July, 1985 to September, 1985. The V. vulnificus was isolated by culture from the necrotizirig skin bullae in three cases, blood culture in two cases, and cerebrospinal fluid(CSF) in one case. The clinical characteristics of V. vulnificus infection in our cases was as follows: 1)All patients were men with their age over forties and the outbreak of the disease was during the summer season. 2) It was suspected that all patients had the previous hepatic problems. 3) The skin lesions showing bullae in three patients and subcutaneous nodules in one patient were noticed. 4) Two patients were showed positive in blood culture and one of thern also showed positive in lesional skin, urine and CSF. Lesional skin culture showed positive in three patients. 5) The isolated v. ulnificus was sensitive to chloramphenicol, erythromycin, gentamycin, kanamycin and cefobid. 6) Two patients died due to sepsis within 48 hours after liospitalization and one patient died due to hepatic failure.
Cefoperazone ; Chloramphenicol ; Erythromycin ; Gentamicins ; Humans ; Kanamycin ; Liver Failure ; Male ; Seasons ; Sepsis ; Skin ; Vibrio vulnificus* ; Vibrio*

A analysis was performed on 1716 pediatric surgical patients, who were supposed to receive elective operations at Seoul National University Childrens Hospital from March 2, 1991 to June 29, 1991. The results can be summarized as follows; 1) Overall cancelled ratio was 19.6%. 2) Departmental distribution of delayed/cancelled elective operations, Plastic surgery 27.0%, pediatric surgery 26.1%, neurosurgery 20.3%, cardiothoracic surgery 18.1%, orthopedic surgery 18.0%, ENT 15.6 ophthalmology 13.9% and urology 13.8%. 3) Major causes of delay/cancellation of elective operatios; Abnormal history and physical examination 54.3 , non-medical 35.0% and abnormal laboratory data only 10.7%. 4) Detailed causative factors of delay/cancellation of elective operations, URI 30.6%, notadmitted 27.9%, heavy schedule 5.9%, abnormal LFT 5.3%, FUO 4.2%, abnormal PTT/PT 2.4%, arrhythmia and cardiac disease 2.4% and further diagnostic evaluation needed 1.8%.
Appointments and Schedules ; Arrhythmias, Cardiac ; Child ; Heart Diseases ; Humans ; Neurosurgery ; Ophthalmology ; Orthopedics ; Physical Examination ; Seoul ; Surgery, Plastic ; Urology

BACKGROUND: In vitro and in vivo studies have shown that inhalation anesthetics inhibit hypoxic pulmonary vasoconstriction (HPV). The aim of this study was to investigate the effect of isoflurane and sevoflurane on HPV in the isolated rabbit lungs. METHODS: Isolated constant-flow perfused lungs from New Zealand white rabbit were randomly allocated to treatment with either isoflurane (n=8) or sevoflurane (n=8). HPV, defined as an increase in pulmonary arterial pressure at constant flow, was elicited by decreasing inspiratory oxygen concentration from 95% to 3% for 5 min. This effect was determined without and with increasing concentration of anesthetics (at 0.5, 1.0, and 2.0 MAC of isoflurane, and at 0.6, 0.9, and 1.2 MAC of sevoflurane). The HPV response in the presence of anesthetics was expressed as a percentage of the pressor response in the absence of anesthetics and dose-response relationship were calculated using the nonlinear least-squares method. RESULTS: The percent hypoxic pressor response (%deltaP) of isoflurane were 100%, 78.4%, 45.1%, and 19.6% at 0, 0.5, 1.0, and 2.0 MAC, respectively. The %deltaP of sevoflurane were 100%, 66.6%, 40.0%, and 22.2% at 0, 0.6, 0.9, and 1.2 MAC, respectively. Values (mean+/-SD) for the half-inhibition values (ED50) were 0.90+/-0.14 and 0.81+/-0.15 MAC, and for the slopes were 1.97+/-0.52 and 1.84+/-0.59 for isoflurane and sevoflurane, respectively. There were no statistical difference between the values for ED50 or between the values for slope. CONCLUSIONS: We conclude that sevoflurane and isoflurane inhibit the HPV reponse in a dose-related manner with same potency and slope.
Anesthetics ; Anesthetics, Inhalation ; Arterial Pressure ; Isoflurane* ; Lung* ; New Zealand ; Oxygen ; Vasoconstriction*

Eosinophilic panniculitis does not a specific disease entity but reptesents a unique reactive pattern that may be associated with inflarnmatory and immunoreactive dis.ases. Its clinical and laboratory data indicate that there is a group of psychiatric and immunoreactivc allergic patients who develop inflammation of the fat, principally eosinophils, and that this reaction is self-lirnited and nonspeeific in most cases, and probably steroid-responsive. We report a case of eosinophilic panniculitis in a 35-year-old man ieho had developed pruritic tender erythematous plaques on hi. legs and right arm with blood eosinooplilia. Microscopic examinat,ion revealed diffuse eosinophilic infiltration in the subcutaneous fat tissue.
Adult ; Arm ; Eosinophils* ; Humans ; Inflammation ; Leg ; Panniculitis* ; Subcutaneous Fat

In order to assess the interaction between halothane and diltiazem on the cardiovascular system and oxygenation, eight mongrel dogs were instrumented so that the following measurements could be made under the influence of drugs heart rate(HR), mean arterial pressure(MAP), central venous pressure(CVP), pulmonary arterial pressure(PAP), pulmonary capillary wedge pressure(PCWP), hemoglobin(Hb) and cardiac output(CO). Systemic and pulmonary vascular resistance(SVR and PVR), coronary perfusion pressure(CPP), cardiac index(CI), oxygen transpor(O2 Flux), oxygen consumption VO2, oxygen extraction ratio(O2ER) and intrapulmonary shunt(Qs/Qt), etc, were calculated by using the above measured parameters. Infusion of diltiazem (8ug/kg/min) following an IV bolus of 0.2mg/kg resulted in a potent vasodilator effect with significant decreases in MAP and SVR, and an increase in CI. Importantly, however, the systemic vasodilator effect of diltiazem was associated with no significant compensatory increase in HR. Halothane anesthesia during continuous infusion of diltiazem produced dose related decrease in HR, CI, MAP, CPP, RPP and O2 Flux, but the previously decreased SVR by diltiazem was not affected by halothane. PCWP, CVP and PVR were not changed throughout the study. So halothane anesthesia during infusion of diltiazem might have some dose related direct negative inotropic and chronotropic effects. Because the decrease in oxygen demand-indicating parameters such as HR and RPP was greater than that in oxygen transport (O2 Flux), the combined use of halothane and diltiazem can be recommended for the patient with ischemic heart disease and angina pectoris, especially in the therapy for decreasing heart rate.
Anesthesia* ; Angina Pectoris ; Animals ; Capillaries ; Cardiovascular System ; Diltiazem* ; Dogs* ; Halothane* ; Heart ; Heart Rate ; Hemodynamics* ; Humans ; Myocardial Ischemia ; Oxygen Consumption ; Oxygen* ; Perfusion