1.A Clinical and Laboratory Study on Infection in Childhood Leukemia.
Jung Hee LEE ; Kwang Hyun KIM ; In Joon SEOL ; Heung Jae LEE ; Hahng LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1986;29(7):1-11
No abstract available.
Leukemia*
2.A Case of Short Arm Deletion of Chromosome 14.
Ra LEE ; Jin CHOI ; Woo Gill LEE ; Chong Moo PARK ; Yong Kyun PAIK
Journal of the Korean Pediatric Society 1981;24(2):164-168
No abstract available.
Arm*
;
Chromosomes, Human, Pair 14*
3.A Case of Acute Megakaryoblastic Leukemia.
Hye Sun JUNG ; Ha Baik LEE ; Hahng LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1985;28(4):390-395
No abstract available.
Leukemia, Megakaryoblastic, Acute*
4.Chromosome Aberrations in Malformed Rat Fetuses Induced with Trypan Blue.
Moo Sang LEE ; Chong Soon WANG
Korean Journal of Urology 1976;17(3):153-161
It is now well known that several human congenital syndromes are accompanied by chromosomal aberrations. Chromosomal aberrations can also be induced by several teratogenic agents in various species of animals when exposed to these agents at certain embryonic development (Installs et al.. 1963 ; Soukup et al., 1967 ; Joneja and Ungthavorn. 1968 ; Roux et al., 1970). A hereditary component in the etiology of urinary tract malformations has been reported in man and animals (Bagg. 1929 ; Deringer and Heston, 1956 ; Monie et al., 1957 ; Roux and Dupuis. 1961 ; Fujikura, 1969). The extent of hereditary influence. however, is difficult to in man, and even the major cause of congenital hydronephrosis is still unknown. The main purposes of this investigation is to determine whether trypan blue which induces congenital anomaly of urinary tract in rat embryos would also induce Chromosomal aberrations in the embryos and the mothers. Sprague-Dawley strain healthy female rats were examined for the spermatozoa in the vaginal smears everyday. Trypan blue solution 1.5% was injected subcutaneously with various doses at different developmental stages of rat embryos. For embryonic studies, the animals were killed on the 20th day of gestation. The total implantations, resorption rates and sex ratios were examined. Under the stereomicroscope. anomalies such as hydronephrosis, renal hypoplasia and agenesis, and anomaly of location. position and rotation of the kidney were examined through the micro-dissection method and confirmed histologically. For Chromosomal studies, the bone marrow cells of mothers and the liver cells of fetuses were examined cytogenetically by means of the culture method of Roux et al. (1970). From the data obtained, results were as follows; 1. Resorption of fetuses, growth retarding effects and chromosomal aberrations of fetuses were increased following the increased doses of trypan blue, but time of injection was more important in production of the malformations. 2. Following the increased doses of trypan blue and early injection, male fetuses were more produced. So it seemed that female fetuses were easily resorpted. 3. The timing of injection with trypan blue exerted greater influence upon the inducement of hydronephrosis than the doses of the chemical, but in cases of other malformations, vice versa. 4. In mothers chromosomal aberrations were related with the doses of the teratogen, but in fetuses, with the timing of injection. 5. So far as trypan blue is concerned, it is probable that there is a close relationship between chromosomal aberration and teratogenecity.
Animals
;
Bone Marrow Cells
;
Chromosome Aberrations*
;
Embryonic Development
;
Embryonic Structures
;
Female
;
Fetus*
;
Humans
;
Hydronephrosis
;
Kidney
;
Liver
;
Male
;
Mothers
;
Pregnancy
;
Rats*
;
Rats, Sprague-Dawley
;
Sex Ratio
;
Spermatozoa
;
Trypan Blue*
;
Urinary Tract
;
Vaginal Smears
5.A Case of Bartter'S Syndrome.
Yung Suk SONG ; Moon Ho CHUNG ; Ha Baik LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1983;26(6):611-615
No abstract available.
Bartter Syndrome*
6.A Case of 45, XO/46, XY Mosaicism With Left Inguinal Herniation of The Ovary.
Young Hoon SONG ; Ha Baik LEE ; Chong Moo PARK ; Yong Giun BAIK ; Poong Man JUNG
Journal of the Korean Pediatric Society 1983;26(6):606-610
No abstract available.
Female
;
Mosaicism*
;
Ovary*
7.Clinical Study of the Paranasal Sinusitis in Childhood.
Young Suk SONG ; Kwang Nam KIM ; Gwi Jong CHOI ; Chong Moo PARK ; Hyung Seok LEE
Journal of the Korean Pediatric Society 1984;27(9):877-882
No abstract available.
Sinusitis*
8.Urinary Excretion of Iron Renal Diseases.
Kyung Ja BANG ; Jaeh Hoon SHIN ; Woo Gil LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1983;26(11):1095-1101
No abstract available.
Iron*
9.Study of Serum Lipids and Lipoprotein in Patients with Nephrotic Syndrome.
Eui Soo PARK ; Jeh Hoon SHIN ; Woo Gill LEE ; Chong Moo PARK
Journal of the Korean Pediatric Society 1983;26(4):349-357
No abstract available.
Humans
;
Lipoproteins*
;
Nephrotic Syndrome*
10.A Study on 657 Skin Tumors.
Baik Kee CHO ; Won HOUH ; Sang il SHIM ; Chong Moo LEE
Korean Journal of Dermatology 1973;11(1):3-8
A study was made on 657 cases of skin tumors, which were obtained mainly as surgical pathology specimens during the period of 12 years and 4 months from January, 1960 to April, 1972, at Departments of Dermatology and Clinical Pethology, Catholic Medical Center in Seoul, and the results were as follow; 1) Of the 657 cases of skin tumors, 470 cases (71. 5%) were benign tumors, 26 casea (4.0%) premalignant lesions and 161 cases (24. 5%) malignant tumors. 2) The ratio of male vs. female was 1: 1 for benign tumor, 1: 1.9 for premalignant lesion and 1. 9: 1 for malignant tumor. 3) Among the benign tumors were 144 cases of cysticercosis, 68 cases of epidermal inclusion cyst, 46 cases of hemangioma and 45 cases of lipoma. 4) Arnong the premalignant lesions were 13 cases of leukoplakia, 5 cases of Nevus sebaceous (Jadassohn) and 4 cases of Bowen's disease. 5) The average age of malignant tumor was 53. 2 years for squamous cell carcinoma, 57. 2 years for basal cell carcinoma, and 35. 6 years for malignant melanoma. 6) The sites of predilection of the squamous cell carcinomas were penis (30. 6%), face (27. 4%) and upper and lower extremities (12.9%). The site of predilection of the basal cell carcinomas was face (88. 5%)., 7) The ratio of squamous cell carcinoma vs. basal cell carcinoma was 2. 4: 1. 8) Among the metastatic cancers of the skin the more frequent primary sites were stomach (3 cases), lung (2 cases) and liver (2 cases).
Bowen's Disease
;
Carcinoma, Basal Cell
;
Carcinoma, Squamous Cell
;
Cysticercosis
;
Dermatology
;
Female
;
Hemangioma
;
Humans
;
Leukoplakia
;
Lipoma
;
Liver
;
Lower Extremity
;
Lung
;
Male
;
Melanoma
;
Nevus
;
Pathology, Surgical
;
Penis
;
Seoul
;
Skin*
;
Stomach