1.Statistical Analysis of Serologic test for Syphilis Durinf five Years.
Keun Woo LEE ; Chong Ju LEE ; Chin Yo CHANG
Korean Journal of Dermatology 1979;17(6):441-450
This paper is studied for statistical anaIysis of 1181 cascs of positive V.D.R.L test among 24414 cases who were visited for annual Physical examination and in or outpatients in the Han Gang Sung Shim Hospital during 5 years and 7 months from January 1972 to July 1977. Clinical survey was carried out with 182 syphilitic patients in the Department of Dermatology, Han Gang Sung Shim Hospital during 19 months from January l976 to July 1977. The results were as follows; 1. Positive rate for V.D.R.L test was 4.8%, and there were statistically significant differences in annual incidence(P<0.01). Biologic false positive rate for V.D.R.L test was 26. 7%, and there were statistically aignificant differences in annual incidence(P<0.01). 2. Departmental analysis such as Dermatology, Urology, Physical Examination and others including Obstetrics and Gynecology, Internal Medicine, Pediatrics etc. were carried out, the results showed that there were statistically significant departmental differences in V.D.R.L positive rate, but no in biologic false positive rate. 3. Biologic false positive rate was high inversely proportional to dilution titer, and that was a statistically significant difference(P<0.01). 4. 182 had syphilis, of whom 106(58. 2%) were latent syphilis and 74(40. 7%) were primary and secondary syphilis. 5. 119(65. 4%) among 182 syphilitic patients were male, most of patients(87.8%) occured in age from 21 to 40 years in the both sex. But there no statistically significant differences in age distribution between males and females. 6. The most predilection site of chancre was coronary sulcus(54.5%). 7. The lesions of secondary syphilis were composed of 18 cases(25%) of condyloma latum, 17 cases(23. 6%) of roseolar syphilid, 17 cases of papulo-squamous syphilid, 13 cases of alopecia syphilitica, 1 case of pustular syphilid, and 6 cases of others. 8. Married patients were nearly two times than single. In women, married. patients were much more(80. 3%) than single, and there were statistically significatnt differences(P<0.01). 9. There were no significant differences in S.T.S positive rate of spouse between infectious and latent syphilis. 10. Occupation distribution of male sexual partners were composed of 35 cases(29. 4%) of waitress, 28 cases(23. 5%) of call-girl, 20 cases(16. 8%) of office-girl, 17 cases of housewife, 12 cases of out of work, 7 cases of student. 1I. For patients with primary, secondary, and latent syphilis, treatment consiste of benzathine penicillin 2. 4 million units intramuscularly on the first visit and repeated three penicillin preparations at 7 days intervals in most of patients.
Age Distribution
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Alopecia
;
Chancre
;
Dermatology
;
Female
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Gynecology
;
Humans
;
Internal Medicine
;
Male
;
Obstetrics
;
Occupations
;
Outpatients
;
Pediatrics
;
Penicillin G Benzathine
;
Penicillins
;
Physical Examination
;
Serologic Tests*
;
Sexual Partners
;
Spouses
;
Syphilis*
;
Syphilis, Cutaneous
;
Syphilis, Latent
;
Urology
2.Cysticercosis and taeniasis in Chollapukdo Province.
Keun Tae LEE ; Chong Hwan KIM ; Chong Tae PARK ; Man Yong LEE
The Korean Journal of Parasitology 1966;4(1):39-45
From 1960 through 1965, 39 cases with epileptic seizure caused by the Cystricercus cellulosae were experienced at Kaejong Mental Hospital, Okku-Gun, Chollapukdo province. The present study was carried on at the area of Chollapukdo province where Cysticercus cellulosae cases were frequently reported. Thrity-nine Cystricercus cellulosae cases(35 male and 4 female) with epileptic seizure visited Kaejong Mental Hospital . Okku-Gun, Chollapukdo during the years of 1960-1965 from various Gun(county): Okku-Gun 13, Kimje-Gun 7, and Soonchang-Gun 6. The high incidence was found at the age group of 20-49 years and the distribution of 214 subcutaneous nodules were as follows: Trunk 56.6 percent, upper extremities 26.6 percent, head and neck 9.3 percent, lower extremities 7.5 percent. According to the address of above 39 cases, taenia infestation of the inhabitants in the area was examined by questionaire form. Plain rural area (Maryong-Ri, Okku-Gun); Among 803 persons interviewed, 4.0 percent or 32 complained the output of Taenia segments. The male group showed higher incidence (6.4 percent) than the female(1.5 percent) . The highest incidence was observed at the age group of 30-39 years. Most of the inhabitants of the area had the eating habit of raw beef and pork. Mountainous rural area(Bok-Heung-Myun, Soonchang-Gun); Among 542 persons interviewed, 33 or 6.1 percent complained Taenia infection. The higher incidence was observed in the male group(8.7 percent) than in the female group(3.1 percent) , and also at the age group of 20-49 years. They had eating habit of raw beef and pork. The species of adult worm were identified by morphological examination. Totally 36 adult worms(Taenia saginata 21, T. solium 15) were obtained from 26 cases, and it was experienced that 5 T. solium were eliminated from one person.
parasitology-helminth-cestoda
;
Taenia solium
;
cysticercus
;
epidemiology
3.A Case of Bowenoid Papulosis.
Suck Whan KIM ; Keun Woo LEE ; Chong Ju LEE ; Eil Soo LEE
Korean Journal of Dermatology 1980;18(5):485-489
We report a case of bowenoid papulosis of the vulva in a 37-year-old woman. Bowenoid papulosis represents a new phenomenon which shows clinical characteristics quite different from classical Bowen's disease and histologic features of squamous cell carcinoma in situ. The patient had several brown-black flat papular lesions on the both sides of the vulva. The lesions were 2 to 9 mm in diameter, somewhat verrucoid and sharply demarcated. On history, these lesions developed from previous several grouped vesicular eruptions which were suspected to the lesions of herpes simplex. Although clinically the lesions appeared benigh, histologic examination showed. changes of squamous cell carcinoma in situ. The lesions were removed with electrodesiccation & curettage and are under observation. It is considered that bowenoid papuIosis should be ruled out by histologic examination in cases of unusual papular lesions of the genitalia in young people and that additional case studies with long-term folIow-up will be needed.
Adult
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Bowen's Disease
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Carcinoma, Squamous Cell
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Curettage
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Female
;
Genitalia
;
Herpes Simplex
;
Humans
;
Vulva
4.A Case of syringocystadenoma Papilliferum.
Keun Woo LEE ; Kae Uck KIM ; Eil Soo LEE ; Chong Ju LEE
Korean Journal of Dermatology 1980;18(6):599-603
Syringocystadenoma papilliferum is a benign skin appendage tumor. The typical lesion occurs most frequently on the scalp or face. The lesion consists most commonly of flesh nodule or plaque that may have a papillary, hyperkeratotic surface. A number of hypotheses as to the origin of this disorder have been put forward by different authors, but its origin still remains obscure. We have recently experienced a case of 31 years old female who had a flesh colored, lobulated tumor mass of 3 * 10cm in the left flank area. The histopathological examination revealed rather typical findings of syringocystadenoma papilliferum.
Adult
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Female
;
Humans
;
Scalp
;
Skin
5.Health Care Utilization and Its Determinants among Island Inhabitants.
Seung Hum YU ; Woo Hyun CHO ; Chong Yon PARK ; Myung Keun LEE
Korean Journal of Preventive Medicine 1987;20(2):287-300
Island regions suffer from a shortage of health care in part because they are less developed, they cover a widespread area relative to the population, and due to transportation barriers. The purpose of this study was to assess the level of illness and the magnitude of medical care utilization, and to investigate the determinants of utilization in these area. The data were collected by means of a household survey conducted from February 16 to 25, 1987 on 5 islands which were selected in consideration of the size of the population, the distance from the main land, and the distribution of health care facilities. The household response rate was 89.1% (491 of 551 households), and 1971 persons were surveyed. The major findings of this study are as follows: 1) The morbidity rate of the island inhabitants was 27.7% during the two weeks, and 25.5 chronic illnesses and 9.1 acute illnesses per 100 persons, were noted. Differences in the magnitude of illness were statistically significant by sex, age, education, and family size. 2) The magnitude of total ambulatory care utilization was 16.8 visits per 100 persons during the two weeks, which was less than that of other regions; and differences in the magnitude of total ambulatory care were statistically significant by sex, age, education, occupation, and family size. 3) Unmet needs were classified as 56.0% in chronic illnesses and 19.6% in acute illnesses; and differences in unmet needs were statistically significant by sex, age, education, occupation, income, and family size. 4) Statistically significant determinants in medical care utilization included the frequency of acute illness and chronic illness, and income in total utilization; the frequency of chronic illness and acute illness, and medical care insurance in physician visits. 5) According to the results of the path analysis, need factors had the greatest effect on utilization, and predisposing factors had more indirect effects through enabling or need factors than direct effects.
Ambulatory Care
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Causality
;
Chronic Disease
;
Delivery of Health Care*
;
Education
;
Family Characteristics
;
Humans
;
Insurance
;
Islands
;
Occupations
;
Transportation
6.Holoacardius Hemisomus Acephalus: A case report.
Tae Jin KIM ; Chong Jai KIM ; Sung Hye PARK ; Suk Keun LEE ; Je G CHI
Korean Journal of Pathology 1989;23(4):487-489
An autopsy case of holoacardius hemisomus acephalus is reported. She weighed 2,190 gm and the height was 38 cm. The head and upper extremities were absent, while the vertebrae and lower extremities were relatively well developed, but severely edematous. The heart, lungs, stomach, liver, spleen, and pancreas were missing, but the lower abdominal organs including kidneys, adrenal, urinary bladder, and genital organs were present. The intestine was blind-ended at jejunal level but opened into a normal anus. The umbilical cord had two arteries and one vein.
7.Experimental Study for Development of New Alloy for Domestic Total Knee Prosthesis
Dae Kyung BAE ; Shang Hoon KIM ; Ju CHOI ; Jae Soo KIM ; Chong Keun LEE
The Journal of the Korean Orthopaedic Association 1986;21(6):971-978
The total knee replacement is an excellent method for the treatment of osteoarthritis, rheumatoid arthritis, etc. of the knee joint. The tendency of the use of total knee prosthesis is increasing now in Korea. But domestic production of the prosthesis is not avaliable and all are imported from abroad. Moreover, these prosthesis are not well adapted to Korean people, and in occation, the custom-made prosthesis should be needed. So, domestic production of the prosthesis is required. For production of new prosthesis, in cooperation with KAIST(Korea Advanced Institute of Science and Technology), we developed the new alloy 15-57 for total knee prosthesis. We conducted an animal experimental study to confirm the biocompatibility of the new alloy. In this experiment, the Zimmer® company vitallium was compared with this new alloy as control study. The results are as follows: 1. Biocompatibility of the new alloy 15-57 is similar than that of Zimmer® company vitallium in histological study of metal-bone interspace area. 2. Surface corrosion of both metal was nearly absent. 3. In summary, the new alloy 15-57 is suggested as an acceptable metal for the production of total knee prosthesis.
Alloys
;
Animal Experimentation
;
Arthritis, Rheumatoid
;
Arthroplasty, Replacement, Knee
;
Corrosion
;
Knee Joint
;
Knee Prosthesis
;
Knee
;
Korea
;
Methods
;
Osteoarthritis
;
Prostheses and Implants
;
Vitallium
8.Fluoroscopic Guided Biopsy of Pulmonary Lesions: A Comparison of Fine Needle Aspiration with Large Needle Cutting Biopsy.
Heon LEE ; Young Min HAN ; Tae Gon JEONG ; Gyung Ho CHUNG ; Myung Hee SOHN ; Chong Soo KIM ; Ki Chul CHOI ; Dong Keun LEE ; Yang Keun RHEE
Journal of the Korean Radiological Society 1995;32(6):883-888
PURPOSE: To compare the diagnostic accuracy between fine needle and large cutting needle biopies. METHODS & MATERIALS: Chest lesion was biopsied consecutively by 19 G or 22 G fine needle and 14 G large cutting needle with interval of 10-20 min. 119 patients confirmed by operation or clinical follow-up were evaluated. RESULTS: There were 65 patient confirmed as malignant lesion and 54 confirmed as benign lesions. Diagnostic accuracy was 87.7%(57/65) for malignancy and 85.2%(46/54) for benign lesion with fine needle. With large cutting needle, it was 90.8%(59/65) for malignancy and 88.9%(48/54) for benign lesion. In the benign lesion, specific diagnostic accuray was 48.1%(26/54) with fine needle, and 64.8%(35/54) with large cutting needle biopsy, respectively. Complications were hemoptysis(n=13, 10.9%), pneumothorax(n=7, 5.9%) and mild to moderate chest pain. Although, it is impossible to compare the complications by the two types of biopsy on same lesion, 10 cases of immediate hemopytsis and more severe chest pain occurred when large cutting needle biopsy was done. CONCLUSION: No significant difference in diagnostic accuracy between fine needle and large cutting needle biopsies was observed in malignant lesion. In benign lesions, larger sample volume may increase the chance of obtaining a specific diagnosis but has no influence on overall diagnostic accuracy of benignity. Thus, we believe that fine needle aspiration biopsy is an accurate, safe, and more tolerable means to be performed as first step for diagnosis of chest lesions.
Biopsy*
;
Biopsy, Fine-Needle*
;
Biopsy, Needle
;
Chest Pain
;
Diagnosis
;
Follow-Up Studies
;
Humans
;
Needles*
;
Thorax
9.Effect of Allopurinol on Brain Infarction Following Middle Cerebral Artery Occlusion in Rats.
Yong Gu CHONG ; Hung Seob CHUNG ; Jung Keun SUH ; Hoon Gap LEE ; Ki Chan LEE ; Jung Wha CHU
Journal of Korean Neurosurgical Society 1990;19(8-9):1210-1220
Of the many potential source of free radial generation, the enzyme xanthine oxidase has been shown to be important in ischemia in non-cerebral tissues. Oxygen-derived free radicals have been implicated in various pathological conditions including ischemia. Xanthine oxidase serve as a source of oxidizing agents such as superoxide radical and hydrogen peroxide. It is investigated that the effect of a specific xanthine oxidase inhibitor, allopurinol, on infarct size in a model of continuous partial cerebral ischemia in rats. Infarct volume was measured by triphenyl tetrazolium chloride staining of brains removed 24 hours after middle cerebral arterial occlusion. Cortical tissue was more effectively protected than basal tissue, especially in allopurinol pretreated group. On histological examinations, hemispheric swelling, PMN cell infiltration and endothelial damage were noted irrespective of allopurinol treatment. It was speculated that free radicals are important in infarction secondary to partial continuous cerebral ischemia and that xanthine oxidase may by the primary source of these radicals.
Allopurinol*
;
Animals
;
Brain Infarction*
;
Brain Ischemia
;
Brain*
;
Free Radicals
;
Hydrogen Peroxide
;
Infarction
;
Infarction, Middle Cerebral Artery*
;
Ischemia
;
Middle Cerebral Artery*
;
Oxidants
;
Rats
;
Superoxides
;
Xanthine Oxidase
10.A Case of Immature Intrapericardial Teratoma.
Hea Young SHIN ; Won Kju CHOE ; Hae Yong LEE ; Chong Kook LEE ; Keun Chang SONG ; Soon Hee JUNG
Journal of the Korean Pediatric Society 1994;37(1):129-134
This paper describes a case of intrapericardial teratoma in a 20-day-old female meonate, who suffered from cyanosis and respiratory difficulty. She was evaluated by echocardiography, chest CT and MRI, the suspected cyanosis and respiratory difficulty. She was evaluated by echocardiography, chest CT and MRI, the suspected intrapericardial mass was identified and surgically removed. The postopervative diagnosis was intrapericardial teratoma, grade II. This case is reported with brief review of some related literature.
Cyanosis
;
Diagnosis
;
Echocardiography
;
Female
;
Humans
;
Magnetic Resonance Imaging
;
Teratoma*
;
Tomography, X-Ray Computed