Pemphigus foliaceus is a chronic vesiculobullous dermatosis which seems to be an autoimmune etiology, and favorable results are usually able to obtain with massive doses of corticosteroids administration and Imuran or other anticancer drugs. Two cases of typical pemphigus foliaceus, who showed cutaneous candidiasis, one with clinical improvements, and the other one who had lung abscesses of aspergilli as a complication of the long-term corticosteroid treatment, have been presented. The diagnosis of pemphigus foliaceus was confirmed by histopathologically subcorneal bullae containing acantholytic cells, also Tzank test and Nikolsky's sign. First case, 37 year old man who has the history of corticostcroid therapy for 3 years tor rheumatoid arthritis, was treated with high dosage of prednisolone and antibiotics with nystatin for cutaneous candidiasis, but lung abscesses of aspergilli developed while we couldn't even notice its progress and he died suddenly because of it although skin lesions showed marked improvement. Second case, 36 year old house wife who has the history of recurrent aphthous stomatitis like eruptions was recovered from pemphigus foliceus after steroid treatment and cutaneous candidiasis after using antibiotics and nystatin. As the complication of corticosteroid therapy, cushingoid feature, blurred vision, and cutaneous candidiasis were occurred in both patients, especially in the first case, hyperglycemia and metabolic alkaloses were developed. And so, as mention of Saunders, we checked the patient's complete history, body weight everyday, and CBC and occult blood every week, but urine sugar or blood sugar and chest X-ray not periodically. We used anabolic agent for osteoporosis, antibiotics, mycostatm, diuretics, and antacid regimen, but failed to deveIopment of aspergillosis.
Adrenal Cortex Hormones ; Adult ; Alkalosis ; Anti-Bacterial Agents ; Arthritis, Rheumatoid ; Aspergillosis ; Azathioprine ; Blood Glucose ; Body Weight ; Candidiasis, Cutaneous ; Diagnosis ; Diuretics ; Humans ; Hyperglycemia ; Lung Abscess ; Nystatin ; Occult Blood ; Osteoporosis ; Pemphigus* ; Prednisolone ; Skin ; Skin Diseases ; Spouses ; Stomatitis, Aphthous ; Thorax

These are the first reported cases of granuloma faciale in two Koreans. Unilateral, slightly elevated violaceous plaque with illdefined margin on cheeck since 20 years ago was observed in 36 year old house-wife, and 40 year old male has had bilateral plaques on both cheek areas since 10 years ago, These plaques were showed the typical histological appearance of granuloma faciale respectively on both of two patients. Literature was briefly reviewed for the discussion of clinical and microseopic findings of this disease. Both patients were treated by intralesional injections and ointment of steroid with relative clinical improvements.
Adult ; Cheek ; Granuloma* ; Humans ; Injections, Intralesional ; Male

A case of glomus tumor was reported with literature review. 36 year old Korean male has had a single corn sized painful nodular eruption on flexor surface of right side forearm since 2 years ago. This single nodule was confirmed histopathologically as glomus tumor but patient had not any trauma and injury history. Simple surgical excision was very excellent for complete cure of this tumor.
Adult ; Forearm ; Glomus Tumor* ; Humans ; Male ; Zea mays

Sclerema neonatorum is a lesion of degeneration, necrosis or crystallization of adipose tissue of new born, and is classified into two types; the generalized type in which death occurs usually within one week without treatment, and the nodular type which is localized and heals spontaneously. In this report, nodular type was presented. Nut to palm sized indurated plaques on deltoid region, upper back and hip were noted 3 weeks after birth. Histopathologic findings of necrosis of subcutaneous tissue with early granulomatous reaction were showed in biopsy specimen. Literature was briefly reviewed for the discussion of clinical and microscopic findings of this disease.
Adipose Tissue ; Biopsy ; Crystallization ; Hip ; Necrosis ; Nuts ; Parturition ; Sclerema Neonatorum ; Subcutaneous Tissue

Five cases of incontinentia pigmenti (Bloch-Sulzberge type) were presented and literature were reviewed. They were all girls. 3cases of them were associated with defects of ectodermal or mesodermal development. As the manifestation of those, malformed teeth in 2 cases, delayed dentition in 3 cases, eye problem in 2 cases, and alopecia in 3 cases were noticed. One of 3 cases had eruptions of lichen striatus on her upper extremities. Especially, family history of involvement of maternal relative in one case was noticed. Diagnosis of them were confirmed by characteristic clinical appearance and histopathologic findings.
Alopecia ; Dentition ; Diagnosis ; Ectoderm ; Female ; Humans ; Incontinentia Pigmenti ; Lichens ; Mesoderm ; Tooth ; Upper Extremity

A case of dermatitis herpetiformis resembling atopic dermatitis is reported. The patient is 45 year-o1d male, who 6 months ago developed the pruritic erythematous vesicular eruptions on the left side of back and it gradually spread to the margin. He was treated with steroid but the lession had undergone exacerbation and remissions. Biopsy was performed on the vesicular lesion and revealed non-acantholytic subepidermal bulla with mild inflammatory cells infiltration and then he was treated with DDS for 2 months with good response.
Biopsy ; Dermatitis Herpetiformis* ; Dermatitis* ; Dermatitis, Atopic* ; Humans ; Male

A clinical observation was made on 53 patients of cryptorchism who had been admitted to the Department of Urology, Kangnam Sacred Heart Hospital during the period from January, 1980 to January, 1983. The following results were obtained: 1. Only 22 patients (41.5%) visited hospital in preschool age (7 years old) and 50 patients (94.3%) before the age of 25. 2. 44 patients (83%) had unilateral involvement and right side (56.6%) was more frequently affected. Bilaterally was noted in 9 patients (17%). 3. 59 testes were surgically explored, 2 cases were confirmed as monorchism. Of the 59 testes, 47 (79.7%) were located in the inguinal canal, 8 (13.6%) in the prepubic region and 2(3.4%) in the abdomen. 4. Among the 59 explorations, 50 cases (84.8%) were found .the hernial sac. Other complication and associated diseases were contralateral hydrocele, ventral curvature of penis, prosis, entropion, intestinal obstruction, triology of Fallot, acute glomerulonephritis and seminoma. 5. Orchiopexy was performed on 53 testes (93%), 4 cases were performed the orchiectomy because of testicular atrophy and excessive short spermatic cord.
Abdomen ; Atrophy ; Cryptorchidism* ; Entropion ; Glomerulonephritis ; Heart ; Humans ; Inguinal Canal ; Intestinal Obstruction ; Male ; Orchiectomy ; Orchiopexy ; Penis ; Seminoma ; Spermatic Cord ; Testis ; Urology

A hydrocele is a common condition which affects all age-group males including babies. It may be defined as a collection of serous fluid within the tunica vaginalis either surrounding the testis or along the spermatic cord or both. Congenital hydrocele is due to complete failure of the processus funicularis closure and most of the fluid collections subside spontaneously during the first year of life. The great majority of hydrocele are primary variety and its etiology is unknown. Secondary hydrocele may be developed to local injury, epididymitis and testicular neoplasms. Chronic hydrocele is common in tropical and subtropical countries where there is a high .incidence of filariasis. Some investigators have reported that hydrocele fluid collections are due to lymphatic defect or peritoneal fluid, It is generally known that hydrocele fluid resembles blood plasma. We performed electrophoresis and electrolytic analysis of hydrocele fluid and serum in 20 cases of hydrocele patients from January, 1981 to September, 1982. And then we obtained the statistical difference between hydrocele fluid and serum. The results are summarized as below: 1. Total protein of hydrocele fluid (4.125 gm/dl) is lower than that of serum (7,535 gm/dl). Statistical difference is greatly significant (p=below 0.005). 2. The proportion of albumin (71.780%) is higher than that of serum (65.685%). The proportion of alpha 2 and gamma globulin (6.880%, 5.535%) are lower than that of serum (10.125%, 8.730%). These statistical difference are greatly significant (p=below 0.005). 3. The proportion of alpha-1 and beta globulin (3.495%, 12.215%) are higher than that of serum (3.105%, 11.935%). There is no statistical significance (p=above 0.1). 4. Sugar of hydrocele fluid (87.65 mg/dl) is lower than that of serum (95.40 mg/dl), but there is no statistical significance (p=above 0.1). 5. Electrolytes of hydrocele fluid are lower than those of serum. Sodium (130 mEq/1); great statistical significance (p=below 0.005). Potassium (3.93 mEq/l); no statistical significance (p=above 0.1). Chloride (97.95 mEq/l); no statistical significance (p=above 0.1).
Ascitic Fluid ; Beta-Globulins ; Electrolytes* ; Electrophoresis ; Epididymitis ; Filariasis ; gamma-Globulins ; Humans ; Incidence ; Male ; Plasma ; Potassium ; Research Personnel ; Sodium ; Spermatic Cord ; Testicular Neoplasms ; Testis

Allogenic peripheral blood stem cell transplantation could be used instead of allogenic bone marrow in treatment of leukemia in children. This 10-year-old female patient with high-risk acute lymphoblastic leukemia received a myeloablative regimen followed by allogenic peripheral blood stem cell transplantation from an HI A-identical sibling donor. Neutrophil recovery to greater than 500/pL occurred at day 11 and platelets recovered to greater than 20,000/pL at day 13. Allogenic peripheral blood stem cell transplantation can be performed safely and may result in a rapid neutrophil and platelet engraftment, without any apparent increased risk of acute graft versus host disease.
Blood Platelets ; Bone Marrow ; Child* ; Female ; Graft vs Host Disease ; Humans ; Leukemia ; Neutrophils ; Peripheral Blood Stem Cell Transplantation* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma* ; Siblings ; Tissue Donors

No abstract available.
Humans ; Hypoplastic Left Heart Syndrome* ; Survivors*