1.Management of Chronic Renal Failure in Childhood.
Journal of the Korean Pediatric Society 1986;29(10):12-17
No abstract available.
Kidney Failure, Chronic*
2.A study of diagnostic significance of simultaneous examination of proteinurla and hematuria in the urinary mass screening.
Young Kyoun KIM ; Chong Guk LEE
Journal of the Korean Society of Pediatric Nephrology 1999;3(1):57-63
Proliferative fasciitis is a benign pseudosarcomatous mesenchymal lesion occurring in the subcutis. The lesion occurs clinically as a tumorous mass that develops within a rather short time in elderly patients. We recently experiecened a case of fine needle aspiration cytology of proliferative fasciitis in the left anterior chest wall of a 72 year-old male patient. The smear revealed two types of cells. One was the large and mostly oval cell with one or two nuclei lying at the periphery of the cell body and abundant basophilic cytoplasm like the ganglion cell. The nuclei were round to oval, had vesicular chromatin and contained prominent nucleoli. The other was the spindle shaped fibroblast with an oval nucleus. The differential diagnosis includes a true tumor such as ganglioneuroma, rhabdomyosarcoma, and liposarcoma and therefore fine needle aspiration cytology is very much indicated in order to exclude these possibilities.
Actinomycosis
;
Aged
;
Basophils
;
Biopsy, Fine-Needle
;
Chromatin
;
Cytoplasm
;
Deception
;
Diagnosis, Differential
;
Fasciitis
;
Fibroblasts
;
Ganglion Cysts
;
Ganglioneuroma
;
Hematuria*
;
Humans
;
Intrauterine Devices
;
Liposarcoma
;
Male
;
Mass Screening*
;
Rhabdomyosarcoma
;
Thoracic Wall
4.Analysis of Urinary Mass Screening for Elementary, Middle and High School Children over a 3-year Period(1995-1997) in Seoul.
Journal of the Korean Society of Pediatric Nephrology 1999;3(2):161-169
In order to evaluate the role of cytopathologic diagnosis of sputum, bronchial washing and bronchial brushing in the diagnosis of lung cancer, we performed this study. The patients included in this study had undergone sputum, bronchial washing and brushing cytology over the 20-month period of 1985 through 1987. The total number of specimens was 5,495 of 2,242 patients, including 4,830 sputa and 665 bronchial washing and brushings. The average number of sputa and bronchial washings and brushings per case was 2.4 and 1.2 respectively. Among them, about 10% were unsatisfactory specimen, and three-fourths were negative specimens. In sputum cytology, the diagnosis of "atypical cells" was given to 3%, "suspicious for malignancy" was given to 1%, and "malignancy" was given to 13%. In bronchial washing and brushing cytology, the diagnosis of "atypical cells", "suspicious for malignancy" and malignancy" was given to 6%, 3%, and 20% respectively. The cases diagnosed as "atypical cells" in cytology were actually malignancy in 95% and 84.8% of sputum and bronchial washing and brushings respectively, and the "suspicious for malignancy" were actually malignancy in 100% in both methods. The detection rates of malignancy were 50.4% and 55.2% in sputum and bronchial washing and brushing respectively, and the specificity was 100% in both methods. The accuracy of cell typing was 92% in sputum and 89.7% in bronchial washing and brushing.
Biopsy, Fine-Needle
;
Child*
;
Diagnosis
;
Humans
;
Lung Neoplasms
;
Mass Screening*
;
Sensitivity and Specificity
;
Seoul*
;
Sputum
5.The clinical evaluation for children with orthostatic proteinuria.
Chan Sung LEE ; Chong Guk LEE ; Sang Woo KIM
Journal of the Korean Pediatric Society 1989;32(11):1520-1525
No abstract available.
Child*
;
Humans
;
Proteinuria*
6.Analysis on the Risk Factors of Vertebral Body Collapse in Metastatic Spine Tumors using MRI.
Chong Suh LEE ; Sung Soo CHUNG ; Saeng Guk LEE
The Journal of the Korean Orthopaedic Association 1999;34(1):111-116
PURPOSE: Recently, MRI has been routinely used in detection and treatment of metastatic spine tumors, but no previous study on prediction and prevention of vertebral body collapse was done using MRI. This study was done to analyze the risk factors of collapse and to define criteria of impending collapse using MRI. MATERIALS AND METHODS: Ninety-five vertebrae of 69 patients with metastatic lesions were evaluated using ratio of involved axial area, sagittal area, costovertebral joint, pedicle, facet joint and uncovertebral joint involvement as independent variables. We defined collapse when there was a fracture of the end plate and loss of vertebral body height over 10%, and degree of collapse was measured as ratio of the body height to the mean of the height of adjacent bodies. The ratio of the involved area was measured on T1-weighted images which showed the largest area of tumor involvement. RESULTS: There noted collapse of the bodies in 11 of 14 cervical vertebrae, 24 of 48 thoracic vertebrae and 15 of 33 lumbar vertebrae. Metastatic involvement on axial images was considered as a significant risk factor regardless of the vertebral level, while costovertebral joint destruction and axial involvement were significant risk factors in the thoracic spine. The criteria of impending collapse were: 51-60% axial involvement of the vertebral body in the cervical and lumbar spine; 61-70% axial involvement of the vertebral body with no destruction of other structures, 21-30% involvement of the vertebral body with destruction of one costovertebral joint or destruction of both costovertebral joints regardless of body involvement in thoracic spine. CONCLUSIONS: Using the above criteria with consideration of the patient s general condition and biologic behavior of the primary tumor, prophylactic stabilization can be performed to prevent ver-tebral body collapse which results in severe pain or paralysis.
Body Height
;
Cervical Vertebrae
;
Female
;
Humans
;
Joints
;
Lumbar Vertebrae
;
Magnetic Resonance Imaging*
;
Paralysis
;
Risk Factors*
;
Spine*
;
Thoracic Vertebrae
;
Zygapophyseal Joint
7.A Case of Tansient Hyperphosphatasemia.
Sung Kee KIM ; Yong Won PARK ; Chong Guk LEE
Journal of the Korean Pediatric Society 2000;43(6):856-860
We examined a male infant with transient increase in alkaline phosphatase(ALP) activity. The 25-month-old infant was admitted to a local hospital because of pneumonia of unknown etiology. Initial laboratory investigation revealed a serum ALP of 11,260U/L, which was comparable to that of bone isoenzyme on the electrophoresis pattern, There was no evidence of hepatitis, skeletal or intestinal diseases. The hyperphosphatasemia disappeared 3 months later. We report a case of transient hyperphosphatasemia diagnosed inci- dentally in the course of management of pneumonia. (J Korean Pediatr Soc 2000;43:856-860)
Alkaline Phosphatase
;
Child, Preschool
;
Electrophoresis
;
Hepatitis
;
Humans
;
Infant
;
Intestinal Diseases
;
Male
;
Pneumonia
8.Detection of Human Papillomavirus DNA 16/18 in Cervical Adenocarcinomas by Polymerase Chain Reaction.
Sang Sook LEE ; Nam Jo PARK ; Chong Guk YOON
Korean Journal of Pathology 1995;29(4):502-510
Twenty-five paraffin-embedded tumor tissues were analyzed for detection of HPV 16 and 18 in cervical adenocarcinoma by polymerase chain reaction with type specific primers and by non-radioactive Southern blot hybridization for confirmation . The suitability of paraffin-embedded tissue as PCR material was confirmed by successful amplification of 100% of cervical specimens with human -globin specific primer. Eighty four percent of the cervical adenocarcinoma tissues were positive for HPV 16 and/or 18. HPV 16 positive rate was 68%, HPV 18 was 60%. The double infection with HPV 16 and 18 was found in 44%. Three cases of the negative specimen in PCR for each type of HPV DNA 16 and 18 were positive in Southern blot hybridization. The total positive rate was 92% for HPV 16 and/or HPV 18, HPV 16 positive rate was 80%. HPV 18 was 72%. The double infection with HPV 16 and 18 was 60%. These results suggest that the pattern of HPV types 16 and 18 is closely associated with carcinogenesis of cervical cancers. HPV type 18 appears to be preferentially related to cervical adenocarcinoma and the poor prognosis of these patients. Therefore, determination of HPV DNA type in cervical carcinoma patients is important in treatment and prognosis.
Humans
;
Adenocarcinoma
9.A Case of Hemolytic Uremic Syndrome.
Seung Cheol LEE ; Chong Guk LEE ; Seong Hwan KIM ; Sang Woo KIM ; Hyun Soon LEE
Journal of the Korean Pediatric Society 1990;33(8):1138-1145
No abstract available.
Hemolytic-Uremic Syndrome*
10.The incidence of complications in severely obese children.
Dong Hwan LEE ; Chul LEE ; Chong Guk LEE ; Yong Seung HWANG ; Sung Ho CHA ; Yong CHOI
Journal of the Korean Pediatric Society 1991;34(4):445-453
No abstract available.
Child*
;
Fatty Liver
;
Humans
;
Hypercholesterolemia
;
Incidence*
;
Obesity