1.Alberta Stroke Program Early CT Score system and its application
International Journal of Cerebrovascular Diseases 2010;18(11):854-859
The Alberta Stroke Program Early CT Score (ASPECTS) is a simple, reliable and systematic approach for evaluating early ischemic changes in middle cerebral artery territory in patients with ischemic stroke. It can be used to conduct rapid semi-quantitative evaluation of ischemic lesions and help to determine the thrombolytic effect and long-term prognosis. The development of multimodal CT and MRI techniques have enriched the application scope of ASPECTS and have improved the validity and reliability of disease judgment. The development of the posterior circulation Acute Stroke Prognosis Early CT Score has made the fast scores extend to posterior circulation stroke, which is beneficial for all the patients with ischemic stroke to conduct early imaging scores. This article reviews the principle of the ASPECTS system, composition, its application in multimodal CT and MRI, as well as the posterior circulation scores.
4.Genetic polymorphism of parotid isoelectric focusing variant protein(PIF) in a Korean population.
Korean Journal of Legal Medicine 1993;17(2):34-43
No abstract available.
Isoelectric Focusing*
;
Polymorphism, Genetic*
5.Primary Lymphosarcoma of the Prostate Gland.
Dong Han KIM ; Dong Hwi KIM ; Chong Soon WANG
Korean Journal of Urology 1965;6(1):45-48
A case of primary lymphosarcoma of the prostate gland proved by Silvermann needle biopsy was presented. Lymphosarcoma of the prostate is a rare condition, and only 23 cases have been reported in medical literature. In Culver's series, 74 per cent were sarcoma of fibrous origin (round cell, spindle cell sarcoma, myxosarcoma), 5 per cent rhabdomyosarcoma, 6 per cent lymphosarcoma, and 10 percent pleuriplastic or un-or de-differentiated sarcoma. A large tumor of the prostate, which is not hard and nodule occurs in a middle aged patient, should be considered of lymphosarcoma of the prostate. A case of lymphosarcoma of the prostate is added to the literature.
Biopsy, Needle
;
Humans
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Lymphoma, Non-Hodgkin*
;
Middle Aged
;
Prostate*
;
Rhabdomyosarcoma
;
Sarcoma
6.The Clinical Observation at the Urinary Tract in Patients with Carcinoma of Cervix.
Dong Han KIM ; Dong Hwi KIM ; Chong Soon WANG
Korean Journal of Urology 1965;6(1):17-20
A study was made of 234 patients with carcinoma of the cervix seen during the period from Aug.-1959 to Dec.-1963, who had come to the Departments of Obstetric and Gynecology of Yonsei Medical Hospital. Intravenous pyelogram, cystoscopy, and urine examination were done and N. P, N. was checked in addition to clinical examination before treatment. Intravenous pyelogram were classified into 1. Non-functioning 2. Hydronephrosis 3. Hydroureter as abnormalities Also cystoscopic finding were classified into 1. Elevation of bladder wall 2. Bullous edema 3. Neoplasm invasion. There were 51 patients who showed abnormality of intravenous pyelogram among the 234 patients with carcinoma of cervix, that was a unilateral abnormality in 38 cases and bilateral in 13 cases. Again, among 24(10.26%) non-functioning kidney in this series the left kidney was affected in 11 cases and right kidney in 6 cases. The 125 of 234 patients showed elevation of bladder wall in cystoscopic finding, and the posterior wall of bladder was elevated similarly in all stages. The urological study of patients with carcinoma of cervix are most essential works in addition to clinical examination, and it should be considered as a systemic disease for all physician especially gynecologist, radiologist, and urologist.
Cervix Uteri*
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Cystoscopy
;
Edema
;
Female
;
Gynecology
;
Humans
;
Hydronephrosis
;
Kidney
;
Neoplasm Invasiveness
;
Urinary Bladder
;
Urinary Tract*
;
Uterine Cervical Neoplasms
7.A study of cardiovascular risk factors revealed in periodic health examination of insured adults.
Chong Hoon LEE ; Dong Yung CHO ; Byung Yeon YU
Journal of the Korean Academy of Family Medicine 1992;13(4):364-375
No abstract available.
Adult*
;
Humans
;
Risk Factors*
8.Survival of adult Clonorchis sinensis in the biliary passages of dead human bodies.
Dong Wik CHOI ; Chong Yoon JOO ; Sung Deok PARK
The Korean Journal of Parasitology 1972;10(2):86-89
Adult Clonorchis sinensis were collected from the biliary passage of nine cases of medico-legal autopsies. The worms were washed repeatedly with tap water and rinsed twice with physiological saline. Incubation took place in Tyrode's medium in order to recover live worms. The number of worms surviving in the medium was determined. The rate of surviving worms showed an unexpectedly high percentage (22.8%) in those cases autopsied 2 days after death. The surviving worm burden dropped sharply to 6.3 and 9.2 percent for those samples taken 5 days after death.
parasitology-helminth-trematoda
;
Clonorchis sinensis
;
autopsy
9.Analysis of the effect of clinical pathway in surgical treatment for 80 patients with mandibular fracture
Chong PENG ; Minjie DONG ; Wanqun CHEN ; Fubao ZHOU
Chinese Journal of Primary Medicine and Pharmacy 2013;20(18):2733-2734
Objective To explore the effect of clinical pathway in surgical treatment for patients with mandibular fracture.Methods 80 patients with mandibular fracture were randomly divided into the conventional therapy group(the control group) (n =40) and the clinical pathway therapy group (CP group) (n =40).The hospitalization time,medical expenses,satisfaction for the treatment,health awareness,and incidence of complications were compared between two groups.Results The results of hospitalization time,medical expenses,satisfaction for the treatment,and health awareness of the CP group were (11.86 ± 3.05) d,(9 115.43 ± 1 689.84) yuan,(91.19 ± 1.02) %,(95.18 ±4.11)points,respectively,which were significantly better than those of the control group [(17.53 ± 2.98)d,(12 066.75 ±2 513.22)yuan,(89.39 ±1.35)%,(82.83 ± 6.56) points] (t =8.41,6.16,6.73,10.01,all P <0.05).The complication rate of the two groups was 2.5%,7.5%,respectively,which had no significant differences (χ2 =0.26,P > 0.05).Concltsion The clinical pathway for mandibular fracture surgery is worthy of promotion.
10.Vancomycin loaded gelatin/β-TCP composite porous scaffolds for the treatment of infected tibial bone defect in rabbit
Jian ZHOU ; Chong BIAN ; Hao ZHOU ; Jiawei WANG ; Jian DONG
Chinese Journal of Orthopaedics 2017;37(8):498-507
Objective To confirm the vancomycin loaded gelatin/β-TCP composite porous scaffolds could be used as sustained-release system,and investigate its efficiency of eliminating infections and repairing bone defects for the treatment of infected bone defects in rabbit.Methods The biodegradable gelatin sponge containing different contents (0,10%,30%,50%) of β-tricalcium phosphate ceramic (β-TCP) was prepared for the controlled-release of vancomycin and labeled with G-0 TCP,G-10 TCP,G-30 TCP and G-50 TCP respectively.Examinations of scanning electron microscopy,porosity analyses and mechanical test were performed.The K-B method was used to investigate the controlled release of vancomycin.Chronic Methicillin-resistant Staphylococcus aureus osteomyelitis models of rabbit were established.After thorough debridement,the infected bone defects were treated in four different groups:blank control group,G-0 TCP group,G-10 TCP group,and G-30 TCP group.At 4 and 8 weeks after implantation,X-ray and histological examinations were carried out to investigate the efficiency of eliminating infections and repairing bone defects.Results The prepared gelatin/β-TCP scaffold exhibited a homogeneously interconnected-3-D porous structure.And the β-TCP granules were localized evenly on the walls of the composite scaffold.There were no significant differences in the pore size of different scaffolds.However,the β-TCP granules can improve the interconnection.The porosity exhibited an obvious increase in G-10 TCP and G-30 TCP composite scaffolds compared with G-0 TCP scaffold.In contrast,too high content of β-TCP granules decreased the porosity.And the porosity exhibited an obvious reduction in the G-50 TCP composite scaffold.The compressive modulus of the vancomycin loaded scaffolds increased with the increase of the β-TCP amount.The scaffold G-0 TCP exhibited the longest duration of vancomycin release and the duration reached 8 weeks.With the increased content of β-TCP granules,the release duration shortened obviously.Compared with the G-50 TCP composite scaffold,the G-10 TCP and G-30 TCP composite scaffolds revealed a better controlled release of the drugs,and the total amount of the drugs was released within 7 weeks.However,the total amount of vancomycin released from the G-50 TCP composite scaffold lasted for 3 weeks.In the treatment of chronic MRSA osteomyelitis of rabbits,the G-30 TCP composite scaffold showed a better performance in the eliminating infections and bone defects repair.At 8 weeks after implantation,signs of osteomyelitis,including osteolysis,development of periosteal reactions,and sequestral bone formation were observed in the animals of blank control group.Signs of infection were absent in other treatment group.In the group treated with G-30 TCP composite scaffold,the bonedefects were repaired completely at 8 weeks after implantation.However,in the groups treated with G-0 TCP and G-10 TCP composite scaffold,the bone defects were not repaired.Conclusion The composite scaffolds could achieve local therapeutic drug levels over an extended duration.And the gelatin with 30% β-TCP granules composite scaffold had optimal porosity,interconnection,mechanical properties and controlled release performances.It exhibited good performances in infection control and bone defect repair in the chronic MRSA osteomyelitis model.