Humans ; Chondrosarcoma, Mesenchymal/pathology* ; Chondrosarcoma/surgery* ; Muscle, Skeletal/pathology* ; Bone Neoplasms/pathology*

Chondrosarcoma/surgery* ; Humans ; Neoplasms, Connective and Soft Tissue ; Soft Tissue Neoplasms

Aged ; Chondrosarcoma ; surgery ; Female ; Fracture Fixation, Internal ; methods ; Humans ; Sternum ; surgery ; Titanium

The authors present a case of primary intracranial extraosseous myxoid chondrosarcoma without any attachment to the cranium or the meninges. The clinical and radiological findings of the primary intraparenchymal tumor are described with a review of the literature concerning cranial and intracranial myxoid chondrosarcoma.
Adolescent ; Adult ; Bone Neoplasms/diagnosis* ; Bone Neoplasms/pathology ; Bone Neoplasms/surgery ; Child ; Chondrosarcoma/diagnosis* ; Chondrosarcoma/pathology ; Chondrosarcoma/surgery ; Female ; Human ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myxosarcoma/diagnosis* ; Myxosarcoma/pathology ; Myxosarcoma/surgery ; Tumor Markers, Biological

Adolescent ; Chondrosarcoma ; pathology ; surgery ; Douglas' Pouch ; pathology ; surgery ; Female ; Humans ; Peritoneal Neoplasms ; pathology ; surgery ; Soft Tissue Neoplasms ; pathology ; surgery

Adenocarcinoma ; metabolism ; pathology ; surgery ; Aged ; Cholecystectomy ; Chondrosarcoma ; metabolism ; pathology ; surgery ; Female ; Gallbladder ; chemistry ; pathology ; surgery ; Gallbladder Neoplasms ; metabolism ; pathology ; surgery ; Humans ; Immunohistochemistry ; Keratin-3 ; metabolism ; S100 Proteins ; metabolism

OBJECTIVETo assess the results and complications of allograft/prosthetic composite arthroplasty for the bone and joint defect after tumor resection.

METHODSAllograft/prosthetic composite arthroplasty included proximal femoral allograft with total hip arthroplasty (12 cases), distal femoral allograft with total knee arthroplasty (10 cases), and proximal tibial allograft with total knee arthroplasty (3 cases). The bone cement was used to fix the prosthesis and allograft-host bone. Before and after operation, 10 patients with osteosarcoma and 4 patients with malignant fibrous histiocytoma received high-dose chemotherapy for 6 cycles.

RESULTSThe mean duration of follow-up was 64 months (36 to 112 months). Three patients died within 37 months. The remaining were alive with tumor-free. There were no dislocation or loose of the prosthesis. Two greater trochanters of the allogenous femur were partially absorbed. Synostosis was found at the allograft-host conjunction of all patients. Using the Enneking functional evaluation system, the mean postoperative score for all patients was 23.4 with a range from 17-27.

CONCLUSIONAllograft/prosthetic composite arthroplasty has the advantages of both techniques and can meet the functional need of patients.

Adult ; Arthroplasty, Replacement ; methods ; Arthroplasty, Replacement, Hip ; Bone Neoplasms ; surgery ; Bone Transplantation ; Chondrosarcoma ; surgery ; Female ; Humans ; Male ; Middle Aged ; Orthopedic Procedures ; methods ; Osteosarcoma ; surgery

Chondrosarcoma ; metabolism ; pathology ; surgery ; Female ; Humans ; Middle Aged ; S100 Proteins ; metabolism ; Soft Tissue Neoplasms ; metabolism ; pathology ; surgery ; Thoracic Neoplasms ; metabolism ; pathology ; surgery ; Thoracic Wall ; Vimentin ; metabolism

Objective:To analyze the diagnosis, treatment and prognosis of patients with rare malignant tumors of the temporal bone. Methods:Four cases of rare temporal bone malignant tumors in our hospital between March 2014 and December 2020 were reviewed, including two cases of chondrosarcoma, one case of fibrosarcoma and one case of endolymphatic cystic papillary adenocarcinoma. There were three males and one female, ages between 28 and 56 years at the time of surgery. Common symptoms included hearing loss, facioplegia, tinnitus, and headache. All patients underwent imaging examinations to evaluate the extent of the lesions. Tumors were removed by subtotal temporal bone resection or infratemporal fossa approach, and postoperative adjuvant radiotherapy was applied if necessary. Results:One of the two chondrosarcoma patients was cured by complete resection of the tumor for 75 months, the other one recurred after the first excision of the tumor and underwent infratemporal fossa approach resection of skull base mass again with no recurrence found yet for 112 months. One patient with fibrosarcoma survived for 28 months after surgery with a positive margin and post-operative radiotherapy. One patient with endolymphatic cystic papillary adenocarcinoma recurred 12 months after subtotal lithotomy, and underwent subtotal temporal bone resection again, combined with radiotherapy. No recurrence was found for 63 months. Conclusion:The incidence of rare temporal bone malignant tumors is extremely low, the location is hidden, and the symptoms are atypical. Attention should be paid for early detection and early treatment. Surgical resection is the main treatment, and radiotherapy can be supplemented in the advanced stage or with a positive margin.
Adult ; Female ; Humans ; Male ; Middle Aged ; Chondrosarcoma/surgery* ; Fibrosarcoma ; Neoplasm Recurrence, Local ; Retrospective Studies ; Skull Base/surgery* ; Skull Base Neoplasms/surgery* ; Temporal Bone/pathology* ; Treatment Outcome

Cerebrospinal Fluid Rhinorrhea ; diagnosis ; etiology ; Chondrosarcoma ; surgery ; Endoscopy ; Enterococcus ; pathogenicity ; Humans ; Male ; Meningitis ; diagnosis ; microbiology ; Middle Aged ; Skull Base ; pathology ; surgery