No abstract available.
Cholangitis, Sclerosing* ; Diagnosis* ; Immunoglobulins*

Cholangitis, Sclerosing ; diagnosis ; therapy ; Humans

Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG4-SC, namely, primary sclerosing cholangitis and cholangiocarcinoma, outline diagnostic criteria for IgG4-SC, provide insight into possible pathophysiological mechanisms underlying the disease and discuss short and long-term management options of this recently described disease.
Cholangiocarcinoma ; Cholangitis, Sclerosing* ; Diagnosis, Differential ; Immunoglobulins*

Cholangitis ; classification ; diagnosis ; etiology ; Cholangitis, Sclerosing ; diagnosis ; Diagnosis, Differential ; Humans ; Immunoglobulin G

Primary sclerosing cholangitis (PSC) is a rare disease entity. The medical therapy for PSC has not been reasonably beneficial. Thus liver transplantation is known to be the ultimate therapy. Because liver transplantation for PSC has been performed rarely in Korea, we report a case of liver transplantation for PSC with a review of the literature. A 35-year-old male was admitted to our hospital with recurrent jaundice for seven years. ERCP showed multiple strictures of intrahepatic duct and an irregularity of the extrahepatic duct wall. Despite medication and endoscopic treatment, liver functions did not imporve and clinical status got worsened. Thus liver transplantation was performed for the correction of hepatic failure. Two months after transplantation, liver functions and general weakness gradually improved and now, one year after liver transplantation, the patient is in normal life.
Adult ; Cholangitis, Sclerosing/diagnosis/*surgery ; Humans ; *Liver Transplantation ; Male

Clonorchiasis procucts diffuse dilatation of the small and medium sized intrahepatic bile ducts and its cholangiogram shows visualization of many bile ducts, especially, tertiary, quaternary, and more peripheral tributaries up to the 6th tributaries. In an attempt to clarify this cholangiographic sign quantitively, we counted the visualized smaller bile ducts in clonorchiasis and compared the number of visualized ducts in normal cholangiogram, recurrent pyogenic chlangitis and carcinoma of the extrahepatic ducts. In clonorchiasis the number of visualized smaller bile ducts was considerably geater than in normal subjects and recurrent pyogenic cholangitis, but there was no singnificant statistical differences in the number of visualized bile duct tributaries between clonorchiasis and carcinoma of the bile ducts. Thus it is considered that too many ducts sign is not a unique cholangiographic finding of clonorchiasis, but we believe that in the presence of this sign with other we l known cholangiographic findings, diagnosis of clonorchiasis is very easy.
Bile Ducts ; Bile Ducts, Intrahepatic ; Cholangitis ; Clonorchiasis* ; Diagnosis ; Dilatation

Duodenal diverticulum appears in 6% of upper gastrointestinal examinations and up to 23% of endoscopic retrograde cholangiopancreaticographies and up to 22% at autopsy. Most of these patients are asymptomatic, but a small fraction develop complications including choledocholithiasis, cholangitis, pancreatitis, diverticulitis, perforation, fistular formation and bleeding. Among these complications, only a few documented cases of bleeding have been reported in the literature, and the experience of endoscopist to the sequence of diagnosis, endoscopic treatment, and subsequent relief of the symptoms remains limited. Aggressive but careful endoscopic examination can help diagnosis of the cases. Also, endoscopic treatment of duodenal diverticular bleeding is very effective and proved to be an effective alternative to surgery. We report 4 patients with duodenal diverticular bleeding in whom both diagnosis and definitive treatment were successful by endoscopy alone.
Autopsy ; Cholangitis ; Choledocholithiasis ; Diagnosis ; Diverticulitis ; Diverticulum ; Endoscopy ; Hemorrhage* ; Humans ; Pancreatitis

Cholangitis ; diagnosis ; etiology ; therapy ; Humans ; Immunoglobulin G ; metabolism

No abstract available.
Adult ; Cholangitis, Sclerosing/*diagnosis/pathology ; Diagnosis, Differential ; Humans ; Liver Cirrhosis, Biliary/diagnosis ; Male

Autoantibodies ; blood ; Cholangitis, Sclerosing ; complications ; diagnosis ; Hepatitis, Autoimmune ; complications ; diagnosis ; Humans ; Liver Cirrhosis, Biliary ; complications ; diagnosis