No abstract available.
Anesthesia* ; Liver Transplantation*

No abstract available.
Risk Factors*

This study was conducted to determine the level of inflammatory cytokines in the cerebrospinal fluid (CSF) of patients with meningitis. All the CSF of the patients were examined by Gram and acid-fast stain, culture, and PCR for Mycobacterium tuberculosis and Mycoplasrma spp..The levels of sugar, protein and leukocytes count were also evaluated in the CSFs. Concentrations of Interleukin (IL)-1B, IL-6, IL-8, tumor necrosis factor (TNF)-a in the CSF were evaluated by the ELISA kit (Genzyme, USA). General bacteria, tubercle bacilli, and Mycoplasma spp. were not detected with stain and culture methods, but, Mycoplasma spp. was detected by PCR method from four (6.3%) patients with meningitis. The mean CSF concentration of IL-1B, IL-6, IL-8, and TNF-cx in the control group were 0.6+/-0.2, 896.8+/-107.6, 50.1+/-5.1, and 4.8+/-1.4 pg/ml, respectively. The mean CSF concentration of IL-1B, IL-6, IL-8, and TNF-a in the patients with aseptic meningitis were 3.8+/-0.6, 1261.6+/-144.3, 466.7+/-42.3, and 10.8+/-2.0 pg/ml, respectively. The mean CSF concentration of IL-1B, IL-6, IL-8, and TNF-a in the patients with mycoplasmal meningitis were 10.2+/-8.1, 1979.5+/-133.8, 459.7+/-96.4, and 17.5+/-5.1 pg/ml, respectively. There were significantly differences in the levels of IL-1B, IL-6, IL-8, and TNF-a between control and patients with aseptic meningitis or Mycoplasmal meningitis (each p<0.001). These results suggest that increased levels of IL-1B, IL-8, and TNF-a could be higly suggestive of meningitis.
Bacteria ; Cerebrospinal Fluid* ; Cytokines ; Enzyme-Linked Immunosorbent Assay ; Humans ; Interleukin-6* ; Interleukin-8* ; Interleukins ; Leukocytes ; Meningitis* ; Meningitis, Aseptic ; Mycobacterium tuberculosis ; Mycoplasma ; Polymerase Chain Reaction ; Tumor Necrosis Factor-alpha

The congenital ball-and-socket ankle joint is a rare condition and is associated with congenital shortening of the lower extrimity and various skeletal abnormalities of the foot. This disease entity was reported in the German literature by Politzer in 1931 and in the English literature by Lamb in 1958. Several series have been reported since, suggesting that the condition may not be as rare as generally thought. This case is, to our knowledge, the first reported in this country.
Ankle Joint ; Ankle ; Foot

No abstract available.
Animals ; Gene Expression* ; Genes, Immediate-Early* ; Rats*

No abstract available.
Charcoal* ; Drug Therapy* ; Mitomycin* ; Stomach Neoplasms*

BACKGROUND: Microdeletion syndromes not detectable by conventional cytogenetic analysis have been reported to occur in approximately 5% of patients with unexplained mental retardation (MR). Therefore, it is essential to ensure that patients with MR are screened for these microdeletion syndromes. Mental retardation syndrome multiplex ligation-dependent probe amplification (MRS-MLPA) is a new technique for measuring sequence dosages that allows for the detection of copy number changes of several microdeletion syndromes (1p36 deletion syndrome, Williams syndrome, Smith-Magenis syndrome, Miller-Dieker syndrome, DiGeorge syndrome, Prader-Willi/Angelman syndrome, Alagille syndrome, Saethre-Chotzen syndrome, and Sotos syndrome) to be processed simultaneously, thus significantly reducing the amount of laboratory work. METHODS: We assessed the performance of MLPA (MRC-Holland, The Netherlands) for the detection of microdeletion syndromes by comparing the results with those generated using FISH assays. MLPA analysis was carried out on 12 patients with microdeletion confirmed by FISH (three DiGeorge syndrome, four Williams syndrome, four Prader-Willi syndrome, and one Miller-Dieker syndrome). RESULTS: The results of MLPA analysis showed a complete concordance with FISH in 12 patients with microdeletion syndromes. CONCLUSIONS: On the basis of these results, we conclude that MLPA is an accurate, reliable, and cost-effective alternative to FISH in the screening for microdeletion syndromes.
*Chromosome Deletion ; Classical Lissencephalies and Subcortical Band Heterotopias/genetics ; DiGeorge Syndrome/genetics ; Humans ; In Situ Hybridization, Fluorescence/*methods ; Laboratories, Hospital ; Mental Retardation/*diagnosis/genetics ; Nucleic Acid Amplification Techniques/*methods ; Prader-Willi Syndrome/genetics ; Williams Syndrome/genetics

No abstract available.
Adenosine* ; Plasma* ; Rats, Inbred SHR* ; Renin*

With the remarkable progress of modern medicine, many monitoring systems and technics have been designed and applied clinically, but the monitoring of the central venous pressure is the most simple, convenient and dependable method to, monitor for a cert patients diagnosis and treatment among the varieties of the monitoring systems. There is need for a convenient and dependable method for estimating fluid volume requirement under diverse circumstances. An adequate circulation depends upon three factors: a. the pumping action of the heart b. the volume of blood being pumped c. the capacity of the vascular system and its resistance. Therefore central venous pressure (C.V.P.) is one of the guides for the adequate circulation. C.V.P. monitoring is indicated in: a. Suspected blood volume deficit: major trauma, severe burns, or penetrating wounds of major body cavity. b. Hypotensive patient c. During and after the open heart surgery or major neurosurgery d. When shock origin is obscure, for diagnostic and therapeutic reasons e. Pulmonary edema and acute heart failure f. Instruction of young physicians in the physiology of the shock. The technic of internal jugular vein cannulation using one of the needle catbeters and its complications are described.
Blood Volume ; Burns ; Catheterization* ; Catheters* ; Central Venous Pressure* ; Diagnosis ; Heart ; Heart Failure ; History, Modern 1601- ; Humans ; Jugular Veins* ; Methods ; Needles ; Neurosurgery ; Physiology ; Pulmonary Edema ; Shock ; Thoracic Surgery ; Wounds, Penetrating

Rehabilitation care requires an organized health care delivery system, stroke, brain injury, spinal cord injury, amputation, severe multiple musculoskeletal injury, and congenital damage to the nervous system frequently result in permanent disability or a temporary serious reduction of bodily function. These diseases or injuries require acute medical treatment at general and tertiary hospitals, but then also require a long period of intensive and comprehensive rehabilitation treatment. Currently, a 3-stage rehabilitation care delivery system, involving acute, subacute (recovery), and chronic (maintenance) rehabilitation, is being considered. Although the concepts underlying this delivery system have not yet been clearly defined, acute rehabilitation should be provided at general and tertiary hospitals for patients with permanent disabilities, an unstable medical condition, and/or a severe temporary reduction of bodily function simultaneously with or immediately after acute medical treatment. Cardiac rehabilitation, respiratory rehabilitation, pressure ulcer management, rehabilitation of severe cerebral palsy, rare diseases, and cancer, for which the cooperation of internal, surgical, and critical care staff is essential, are included in acute rehabilitation. Additionally, intensive and comprehensive inpatient subacute (recovery) rehabilitation should be provided for patients with severely impaired bodily function who are medically stable. Subsequently, chronic rehabilitation may be required for patients who need postural changes throughout the day, those who require rehabilitation treatment intended to prevent long-term complications and to ensure the maintenance of body function, those who show shortness of breath or dysphagia, and those who show little improvements of bodily function, making discharge into the home difficult. These services can be categorized as outpatient, visiting, or long-term rehabilitation services.
Amputation ; Brain Injuries ; Cerebral Palsy ; Critical Care ; Deglutition Disorders ; Delivery of Health Care ; Dyspnea ; Humans ; Inpatients ; Nervous System ; Outpatients ; Pressure Ulcer ; Public Health ; Rare Diseases ; Rehabilitation* ; Spinal Cord Injuries ; Stroke ; Tertiary Care Centers