It is well known that early diagnosis and early treatment is very important for the patient with congenital dislocation of the hip joint to have favorable function in the whole life. The goal of treatment is to replace the hip restored in containment with anatomical position. There have been various treatments in both conservative and surgical methods. In the past, conservative treatment has been prevalled, and since Salter has advocated innominate osteotomy, this surgical method could be successively replaced the treatment of congenital dislocation of the hip in the older age group. We have experienced 40 congenital dislocation of the hips out of 35 patients at the Department of Orthopaedic Surgery in National Medical Center. Clinical analysis has been performed, with average 3 years and 9 months follow-up study and the resuits are as follows. 1. Majority of the case was treated primarily at age between 12-24 months. 2. The preponderence of girl to boys was 33:2. 3. The affection ratio of left to right side was nearly equal as 16:14. Five out of 35 cases were involved at both sides. 4. The chief complaints were almost limping and limb shortening. 5. In 40 hips from 35 patients, 12 hips were treated by closed reduction, 3 hips by open reduction and 18 hips by Salters innominate osteotomy in the age group under 7 years old. By Seddon's classification, we obtained 11 excellent and good results out of 12 cases treated by closed reduction, 2 out of 3 hips by open reduction and 15 out of 18 hips by Saiters innominate osteotomy. 6. We performed femoral derotation osteotomy in 2 cases, 9 and 11-year-old patients. Steels operation with femoral shortening in 9-year-old girl and bilateral THR on 2 hips in 44-year-old patient. Result of derotation osteotomy belonged to clinical failure and THR belonged to excellent group by Seddons classification. 7. We experienced one case of avascular necrosis transiently, but finally healed delaying weight bearing.
Adult ; Child ; Classification ; Containment of Biohazards ; Dislocations ; Early Diagnosis ; Extremities ; Female ; Follow-Up Studies ; Hip Joint ; Hip ; Humans ; Methods ; Necrosis ; Osteotomy ; Steel ; Weight-Bearing

Extraosseous tuberculosis of the extremities is relatively rare even in the wide spread incidence of bone and joint tuberculosis. And few reports about extraosseous tuberculosis of the extremities have been published in the literatures. Eight cases of the extraosseous tuberculosis of the extremities were experienced at the Department of Orthopaedic Surgery, National Medical Center, from 1975 to Sep. 1979. Five out of 8 extraosseous tuberculosis were tenosynovitis and the others were bursitis in location. All cases were surgically excised and combined with antituberculous chemotherapy, and primarily cured.
Bursitis ; Drug Therapy ; Extremities ; Incidence ; Tenosynovitis ; Tuberculosis ; Tuberculosis, Osteoarticular

No abstract available.
Vaccination*

No abstract available.
Pancreaticoduodenectomy*

Invasion of enteric bacteria, such as Salmonella and invasive E. coli, into intestinal epithelial cells induces proinflammatory gene responses and finally epithelial cell apoptosis. In this study, we asked whether invasive bacterial infection of human intestinal epithelial cells could upregulate cyclooxygenase-2 (COX-2) gene expression and whether increased COX-2 expression could influence intestinal epithelial cell apoptosis. Expression of COX-2 mRNA and prostaglandin (PG) E production were upregulated in HT-29 colon epithelial cells which were infected with S. dublin or invasive E. coli, as examined by quantitative RT-PCR and radioimmunoassay. Inhibition of COX-2 expression and PGE2 production using NS-398, a specific COX-2 inhibitor, showed a significant increase af epithelial cell apoptosis and caspase-3 activation in HT-29 cells infected with invasive bacteria. However, the addition of valerylsalicylate, a specific COX-1 inhibitor, did not change apoptosis in S. dublin-infected HT-29 cells. These results suggest that upregulated COX-2 expression and PGE2 production in response to invasive bacterial infection could contribute to host defense by inhibiting apoptosis of intestinal epithelial cells.
Apoptosis* ; Bacteria ; Bacterial Infections* ; Caspase 3 ; Colon ; Cyclooxygenase 2 ; Dinoprostone ; Enterobacteriaceae ; Epithelial Cells* ; Gene Expression ; HT29 Cells ; Humans ; Prostaglandin-Endoperoxide Synthases* ; Radioimmunoassay ; RNA, Messenger ; Salmonella

Pyogenic granuloma is not an uncommon oral cavity lesion and is a benign soft tissue tumor arising from the connective tissue of the skin or mucous membrane. We have reported a pedunculated tumor on the junctional area of the left side of upper lip and buccal mucosa which was developed without any history of trauma and clinically it was composed with condyloma acuminatum. Histopathological findings showed many newly formed blood vessels with marked endothelial swelling and collarette formation of rete ridges of epidermis. The lesion was completely subsided after surgical excision.
Blood Vessels ; Connective Tissue ; Epidermis ; Granuloma, Pyogenic* ; Lip ; Mouth ; Mouth Mucosa* ; Mucous Membrane ; Skin

To investigate the heterogeneity of fibroblast proliferation rate depending on the depth of dermis in the psoriatic skin lesions, fibroblasts were obtained from the upper and lower dermis of the forearm skin lesions in 9 psoriatir, patients and of the comparable sites in 7 healthy persons respectively, and were cultured. The in vitro proliferation rates of the fibroblasts were calculated by measuring the efficiency af cell attachment, cell numbers on varying days of culture and the population doubling time during the 3rd passage of subculture. The results were as follows: 1, The efficiencies of cell attachment at 24 hours after seeding were not statistically different between the upper derrnal fibroblasts and the lower ones in both psoriatic skin lesions and normal skins. 2. By rneasuring the cell numbers and the population doubling times, the prolifeatior rate of the upper der mal fibroblasts was greater than that of the lower ones in both psoriatic skin lesions and normal skins and that the fibroblastic proliferation rate was significantly inereased in the psoriatic skin lesion compared to the normal skin.
Cell Count ; Dermis* ; Fibroblasts* ; Forearm ; Humans ; Population Characteristics ; Skin*

PURPOSE: To examine the effects of power walking exercise on fatigue and overweight in college students with Taeumin constitution. METHODS: According to results of the constitution diagnosis (QSCC II), 58 students who were identified as Taeumin, whose BMI was over 23 were assigned to one of three groups. The power walking group walked fast at a speed of 7,000 steps per hour using a pedometer, and the walking group walked at a speed of 5,000 steps per hour. There was no treatment with control group. Each group's fatigue level, blood lipids and body composition before and after the experiment were compared and analyzed. RESULTS: Total fatigue and total cholesterol decreased significantly in the power walking group compared to the walking group and the control group. Weight decreased significantly in the power walking group compared to the control group, and percentage of body fat decreased significantly in both the power walking group and the walking group compared to the control group. CONCLUSION: When power walking exercise was used with overweight Taeumin students, fatigue, blood lipid, weight and percentage of body fat decreased significantly.
Adipose Tissue ; Body Composition ; Cholesterol ; Constitution and Bylaws ; Fatigue ; Humans ; Overweight ; Walking

No abstract available.
Bile*

No abstract available.
Arteriovenous Fistula* ; Fistula*