1.Proposal of a Screening Program for Gastric Cancer in Korea.
Journal of the Korean Medical Association 2002;45(8):964-971
Stomach cancer is one of the major causes of cancer deaths in Korea. It has been well known, like other solid tumors, that cancer stage at diagnosis is the most important prognostic factor in gastric cancer. Previous studies from Japan have revealed that screen-detected gastric cancers showed an earlier stage distribution and had a lower mortality rate than symptom-diagnosed cases. Considering the high provalence and substantial mortality from gastric cancer in Korea, it seems necessary to establish a well organized nationwide screening program. In this regard, consensus meeting was held in January, 2002 in conjunction with The Koean Gastric Cancer Association and National Cancer Center in Korea. In this meeting, specialists from gastroenterology, surgery and radiology drew a conclusion as follows : biannual screening for people aged 40 years and over either by endoscopy or upper gastrointestinal series. During the screening endoscopy, biopsy can be performed if necessary, and specimens should be examined by pathologist. Screening test should be performed in authorized hospital or mobile unit by qualified doctors.
Biopsy
;
Consensus
;
Diagnosis
;
Endoscopy
;
Gastroenterology
;
Japan
;
Korea*
;
Mass Screening*
;
Mortality
;
Specialization
;
Stomach Neoplasms*
2.Clinicopathologic Features and Treatment Results.
Journal of the Korean Gastric Cancer Association 2002;2(3):136-139
No abstract available.
3.Solitary Morphea Profunda with Incidental Acantholysis.
Young Min PARK ; Sang Hyun CHO ; Baik Kee CHO
Annals of Dermatology 1999;11(2):78-81
Solitary morphea profunda is a rare form of scleroderma, characterized clinically by a solitary sclerotic plaque, and histologically by marked dermal and subcutaneous fibrosis with an inflammatory infiltrate. We describe another case of this entity presented with an ulcerative, indurated plaque on the left iliac crest, which histologically revealed a focal incidental acantholysis in the overlying epidermis and a marked eosinophilic infiltration through the dermis to the sub-cutaneous tissue.
Acantholysis*
;
Dermis
;
Eosinophils
;
Epidermis
;
Fibrosis
;
Scleroderma, Localized*
;
Ulcer
4.Solitary Neurofibroma on the Lower Lip.
Do Hyun LEE ; Baik Kee CHO ; Hyun Jeong PARK
Korean Journal of Dermatology 2013;51(4):299-300
No abstract available.
Lip
;
Neurofibroma
5.A Case of Allergic Contact Dermatitis Due to Nickel Following the Acupuncture.
Jungyoon MOON ; Hyun sun PARK ; Soyun CHO ; Hyun Sun YOON
Korean Journal of Dermatology 2017;55(7):469-470
No abstract available.
Acupuncture*
;
Dermatitis, Allergic Contact*
;
Nickel*
6.A Case of Cutaneous Horn-Like Cutaneous Focal Mucinosis.
Do Hyun LEE ; Baik Kee CHO ; Hyun Jeong PARK
Korean Journal of Dermatology 2012;50(11):1014-1015
No abstract available.
Mucinoses
7.Organotypic Culture of HaCaT cells: Use of Dermal Substrate that Combines de-epidermized Dermis with Fibroblast-populated Collagen Matrix.
Kwang Hyun CHO ; Dong Youn LEE ; Kyoung Chan PARK ; Kwang Hyun CHO
Annals of Dermatology 2002;14(3):137-142
BACKGROUND: The immortalized human keratinocyte line, HaCaT cells have been widely used as substitutes for normal epidermal keratinocytes. Recently, reconstruction of a skin equivalent using HaCaT cells showed a multilayered epithelium,but somewhat different tissue architecture as compared with normal epidermis. OBJECTIVE: In this study, using HaCaT cells we tried to reconstruct an epidermis resembling more closely to normal epidermis than the previous results. MATERIALS AND METHODS: HaCaT cells were cultured in air-liquid interface on a recently developed dermal substrated in our laboratory, de-epidermized dermis (DED) raised on fibroblast-populated collagen matrix and the result was compared with those on DED or fibroblast-populated collagen matrix alone. RESULTS: HaCaT cells on the new dermal substrate formed a multilayered epithelium with rete ridges, showing rather orderly cellular organization compared with those on fibroblast-populated collagen matrix. However, horny and granular layers were not observed contrary to normal epidermis. Immunohistochemical studies revealed that differentiation markers such as keratin 1, keratin 6 and involucrin showed the similar pattern to those in HaCaT cells cultured on fibroblast-populated collagen matrix. Markers of terminal differentiation, loricrin and filaggrin were not expressed contrary to normal epidermis. CONCLUSION: These results suggest that organotypic culture HaCaT cells on the dermal substrate combines DED with fivroblast-populated collagen matrix results in incomplete differentiation of HaCaT cells contrary to normal keratinocytes.
Antigens, Differentiation
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Collagen*
;
Dermis*
;
Epidermis
;
Epithelium
;
Humans
;
Keratin-1
;
Keratin-6
;
Keratinocytes
;
Skin
8.A Case of Diffuse Biphasic Cutaneous Amyloidosis.
Young Min PARK ; Koo Seog CHAE ; Sang Hyun CHO ; Baik Kee CHO ; Chan Kum PARK
Annals of Dermatology 1997;9(4):281-285
We described a case of diffuse biphasic cutaneous amyloidosis, a unique form of localized cutaneous amyloidosis. A 41-year-old man has gradually developed a lichenoid papular and a grouped spotted pigmented macular eruption on the trunk and upper extremities over the past 15 years. Histopathologic examination revealed that amyloid deposits were present in the papillary dermis. It was confirmed by Congo red staining, immunohistochemistry and electron microscopy. There was no evidence of systemic amyloidosis.
Adult
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Amyloidosis*
;
Congo Red
;
Dermis
;
Humans
;
Immunohistochemistry
;
Microscopy, Electron
;
Plaque, Amyloid
;
Upper Extremity
9.Two Cases of Epithelioid Sarcoma with Immunohistochemical Study.
Duk Kyu CHUN ; Kwang Hyun CHO ; Seong Hoe PARK
Annals of Dermatology 1992;4(1):26-31
Two typical cases of epithelioid sarcoma were examined by immunohistochemical stain using antibodies to epithelial membrane antigen, carcinoembryonic antigen, vimentin and cytokeratin. Both cases showed positive reactivity for the four kinds of antibodies. These results point to the fact that epithelioid sarcoma simultaneously expresses epithelial markers and characteristic mesenchymal phenotypes. Epithelioid sarcoma appears to be a tumor derived from a multipotential mesenchymal cell with multidirectional differentiation.
Antibodies
;
Carcinoembryonic Antigen
;
Keratins
;
Mucin-1
;
Phenotype
;
Sarcoma*
;
Vimentin
10.A Case of Milia-like Idiopathic Calcinosis Cutis in an Elderly Person.
Hwayoung JUNG ; Miri KIM ; Baik Kee CHO ; Hyun Jeong PARK
Korean Journal of Dermatology 2014;52(4):287-288
No abstract available.
Aged*
;
Calcinosis*
;
Humans