1.Pathologically Diagnosed Giardia Lamblia Enteritis: A case report.
An Hi LEE ; Kyoung Mee KIM ; Se Hyun CHO ; Sang In SHIM
Korean Journal of Pathology 1996;30(4):361-363
Giardiasis is one of the most common causes of infectious diarrhea and it has a worldwide distribution. Although it is a relatively common disorder, histologically confirmed Giardiasis is a rare occurrence and there have been no previous reports in Korea. A 34-year-old man presented with a 2-year history of epigastric discomfort and left flank pain. On stool examination, many cystic forms of Giardia lamblia were noted. In biopsy specimens of the small intestine, there was moderate chronic inflammatory cell infiltration and several trophozoites of Giardia were observed in the intervillous space and luminal surface. The trophozoites were pear shaped symmetrical organisms with two nuclei, and measured 9~10 micrometer in length.
Male
;
Humans
;
Biopsy
2.The Mechanism of Blood Flow Generation during Closed Chest Cardiac Massage: Transesophageal Echocardiographic Monitoring.
Young Hi LEE ; In Chul CHOI ; Myung Won CHO
Korean Journal of Anesthesiology 1997;33(5):957-961
The mechanism of forward blood flow during closed chest cardiac massage remains controversial. Two theories have been suggested: the cardiac pump theory and the thoracic pump theory. Case report is presented to illustrate the use of transesophageal echocardiography during cardiopulmonary resuscitation. The findings included right and left ventricular compression, closure of the mitral valve during compression, opening of the mitral valve during the release phase, and atrioventricular regurgitation during compression, indicating a positive ventricular-to-atrial pressure gradient. These findings suggest that direct cardiac compression was the predominant mechanism of forward blood flow during cardiopulmonary resuscitation in this patient. Transesophageal echocardiography offers a new approach for study of the flows and cardiac morphologic features during chest compressions in humans. An understanding of the actual mechanisms involved is necessary if improved cardiopulmonary resuscitative techniques are to be rationally developed for enhancing the outcome of resuscitation.
Cardiopulmonary Resuscitation
;
Echocardiography*
;
Echocardiography, Transesophageal
;
Heart Massage*
;
Humans
;
Mitral Valve
;
Resuscitation
;
Thorax*
3.Synthesis of anti-HBs by cultured lymphocytes from uremic HBsAg carriers : effects of interferon.
Hi Bahl LEE ; Sung Won CHO ; Choon Sik PARK
Korean Journal of Nephrology 1993;12(4):533-541
No abstract available.
Hepatitis B Surface Antigens*
;
Interferons*
;
Lymphocytes*
4.A Case of Anetoderma Overlying Pilomatricoma.
Sang Hee HAM ; Young Min PARK ; Sang Hyun CHO ; Baik Kee CHO ; An Hi LEE
Korean Journal of Dermatology 1998;36(2):317-320
Anetoderma is loose and wrinkled skin lesions that show the characteristic histopathological feature of focal loss of elastic fibers in the dermis. The primary type of anetoderma arises in clinically normal skin and the secondary type replaces the lesions of associated disorders including various infections, infiammatory diseases and tumors. However, anetoderma due to pilomatricoma is very rare. Our patient, a 21-year-old female, presented with a soft and wrinkled skin overlying a firm, pedunculated tumor on her left upper arm. The histopathological examination showed anetodermic cutaneous changes which were associated with the underlying pilomatricoma.
Anetoderma*
;
Arm
;
Dermis
;
Elastic Tissue
;
Female
;
Humans
;
Pilomatrixoma*
;
Skin
;
Young Adult
5.HLA Typing, Islet Cell Antibody and C-Peptide of Insulin Dependent Diabetes Mellitus in Children.
Hyeong Rae CHO ; Sei Joong KO ; Duk Hi KIM ; Hyun Chul LEE ; Kap Bum HUH
Journal of the Korean Pediatric Society 1990;33(12):1705-1712
No abstract available.
C-Peptide*
;
Child*
;
Diabetes Mellitus*
;
Histocompatibility Testing*
;
Humans
;
Insulin*
;
Islets of Langerhans*
6.A Study of the p53 Tumor Suppressor Gene Mutations in Hepatocellular Carcinomas in Korean Patients.
Jin Ho JEONG ; Kwang Soo LEE ; Yul Hi CHO
Journal of the Korean Surgical Society 1998;55(5):726-736
BACKGROUND: Hepatocellular carcinoma is the second most common cause of death among cancers in Korea. Epidemiological studies have revealed the carrier state of the hepatitis B virus and the dietary intake of aflatoxin B1 as possible causative agents of this neoplasm, but the precise molecular bases are still unknown. METHODS: We examined 24 cases of human hepatocellular carcinomas in Koreans for the presence of p53 aberrations in exons 4 to 9 of the gene by using single-strand conformation polymorphism (SSCP) analysis of the polymerase chain reaction (PCR) products. RESULTS: Four (17%) of the tumors demonstrated a SSCP band shift, 1 in exon 6 and 3 in exon 7. All of the abnormal DNA fragments were further characterized by direct DNA sequencing. All the mutations were missense mutations. One was an A to G transition at the second nucleotide of codon 214; 2 were G to T transversions at the second nucleotide of codon 245; and one was a G to T transversion at the third nucleotide of codon 249, a mutational 'hot spot' at which mutations have been frequently found, especially when aflatoxin B1 plays an important role in the hepatocarcinogenesis. CONCLUSIONS: These results indicate that the possibility of aflatoxin B1 being a causative agent of hepatocarcinogenesis in Korea can not be excluded.
Aflatoxin B1
;
Carcinoma, Hepatocellular*
;
Carrier State
;
Cause of Death
;
Codon
;
DNA
;
Epidemiologic Studies
;
Exons
;
Genes, Tumor Suppressor*
;
Hepatitis B virus
;
Humans
;
Korea
;
Mutation, Missense
;
Polymerase Chain Reaction
;
Polymorphism, Single-Stranded Conformational
;
Sequence Analysis, DNA
7.The clinical studies on acute poisoning of infants and children visited the emergency room in rural area.
Chang Hi LEE ; Gyu Dong CHOI ; Hyeon Soo HAN ; Hye Heon HWANG ; Myung Ho CHO
Journal of the Korean Academy of Family Medicine 1991;12(2):40-46
No abstract available.
Child*
;
Emergencies*
;
Emergency Service, Hospital*
;
Humans
;
Infant*
;
Poisoning*
8.Effects of Histamine on Nerve Block with Lidocaine.
Korean Journal of Anesthesiology 2003;44(6):861-866
BACKGROUND: The failure to achieve satisfactory anesthesia following the administration of local anesthetic agents in acute inflammatory tissues is a recognized clinical phenomenon. Many inflammatory mediators can reduce the threshold of nociception during inflammation, and histamine, one of the most important inflammatory mediator, may attenuated local anesthetic effect during inflammation. The purpose of this study was to investigate if histamine can antagonize a lidocaine induced nerve block in vitro. METHODS: Recordings of the compound action potentials (CAP) of A-fiber components were obtained from the isolated sciatic nerves of male Sprague-Dawley rats. The nerve sheath of the sciatic nerve was removed and desheathed nerve was mounted in a recording chamber. Single pulse stimuli (0.5 msec, supramaximal stimuli) were repeatedly applied (2 Hz) to one end of the nerve and CAP recordings were made at the other. The effect of histamine on the suppression of CAP by lidocaine and the effect of histamine on the recovery time to the nerve block by lidocaine were measured. RESULTS: Compared with the baseline amplitude, the amplitudes of CAP were 11.7+/-4.1% for the lidocaine group, 18.3+/-4.6% for the lidocaine histamine 0.05% group, and 26.1+/-5.6% for the lidocaine histamine 0.5% group. Nerve block recovery times were: 38.6+/-3.5 min for the modified Krebs group, 29.8+/-4.2 min for histamine 0.05% in the modified Krebs group, and 19.2+/-1.1 min for histamine 0.5% in the modified Krebs group. CONCLUSIONS: Histamine shortened the recovery time induced by lidocaine. We suggest that histamine may significantly attenuate the effects of local anesthetics in inflammed tissue.
Action Potentials
;
Anesthesia
;
Anesthetics
;
Anesthetics, Local
;
Histamine*
;
Humans
;
Inflammation
;
Lidocaine*
;
Male
;
Nerve Block*
;
Nociception
;
Rats, Sprague-Dawley
;
Sciatic Nerve
9.A Case of Severe Serotonin Syndrome Induced by Fluoxetine and Sertraline.
Jin Sook CHEON ; Sang Shin LEE ; Sung Hi KIM ; Woong CHO
Journal of the Korean Society of Biological Psychiatry 2001;8(1):167-174
A 54-year-old male patient who was suffering from bipolar I disorder for 19 years and was admitted to the National Bugok Mental Hospital due to a depressive episode, was referred to the Kosin University Gospel Hospital. On arrival at the emergency room, he had confused mentality with disorientation, memory impairment, hypomania, marked anxiety and hyperirritability. The change of neuromuscular activity such as ataxia, gait disturbance, tremor, shivering, myoclonus and epileptic seizures was also shown. In addition, the symptoms and signs of autonomic instability including diaphoresis, tachycardia, hypotension, fever and facial flushing were noticed. The above symptoms developed after the administration of sertraline successive to the discontinuation of fluoxetine without any washout period. The degree of severity seemed to be severe because he had epileptic seizures, fever and hypotension. He was recovered from the severe serotonin syndrome by the supportive symptomatic treatment with sodium valproate, clonazepam, lorazepam and cyproheptadine after cessation of the selective serotonin reuptake inhibitors during hospitalization. Therefore, this rare case of severe serotonin syndrome was reported and related literatures were also reviewed.
Anxiety
;
Clonazepam
;
Cyproheptadine
;
Emergency Service, Hospital
;
Epilepsy
;
Fever
;
Fluoxetine*
;
Flushing
;
Gait Ataxia
;
Hospitalization
;
Hospitals, Psychiatric
;
Humans
;
Hypotension
;
Lorazepam
;
Male
;
Memory
;
Middle Aged
;
Myoclonus
;
Serotonin Syndrome*
;
Serotonin Uptake Inhibitors
;
Serotonin*
;
Sertraline*
;
Shivering
;
Tachycardia
;
Tremor
;
Valproic Acid
10.Acute Pulmonary Edems during the Operative and Post-operative Period under General Anesthesia - 7 case report.
Myung Duk CHO ; U mi KIM ; Choon Hi LEE
Korean Journal of Anesthesiology 1982;15(2):205-214
The author have had experience with seven cases of acute pulmonary edema. There are many predisposing factors for acute pulmonary edema, namely, left ventricular failure due to cardiac disease or overloading, hypoalbuminemia, pulmonary capillary endothelial damage from bacterial infections, toxins or irritant gases, rarely central nervous system injuries and pulmonary hypersensitivity reactions. For these presented cases, we believe that overloading, hypoalbuminemia, bile pneumonitis were the causative factors. There are many preventive measures and treatment for acute pulmonary edema. We conclude that prompt recognition and attention by the anesthesiologist are the most important preventive measures.
Anesthesia, General*
;
Bacterial Infections
;
Bile
;
Capillaries
;
Causality
;
Central Nervous System
;
Gases
;
Heart Diseases
;
Hypersensitivity
;
Hypoalbuminemia
;
Pneumonia
;
Pulmonary Edema