Chlamydia Infections/epidemiology* ; Chlamydia trachomatis ; Genitalia, Male ; Humans ; Male

The study aimed to investigate the situation, clinical characteristics and the value of PCR in diagnosis of urogenital chlamydia infection. During 3 months (6/2003-9/2003) we had studied 416 patients with urogenital discharge attending at laboratory department of the National Institute of Dermatology of Vietnam (NIDV). They had been tested for the C.T by using PCR and /or Hexagon (EIA). Results: 94 patients were detected C.T infection, the rate is 22.6%. In which, number of the women is 3.66 times higher than the men. The highest frequency of C.T infection is group of age from 25 to 34, and patients who live in urban. The most common symptom is cervicitis (in female) and urethritis, pain or burning during urenation (in male). PCR was positive in some cases which were negative with Hexagon test.
Chlamydia Infections ; Polymerase Chain Reaction ; Diagnosis

OBJECTIVE: Endocervical infection of Chlamydia trachomatis is one of the most common sexually transmitted diseases(STD) in women, and it usually disseminates into the upper genital tract, especially at the uterine exploration. This study was performed to investigate the prevalence rate of endocervical Chlamydia trachomatis in infertile women with the application of polymerase chain reaction(PCR) for the detection of Chlamydia trachomatis DNA. METHODS: From March, 1996 to October, 1999, endocervical swabs were obtained in 101 infertile patients at SNUH. Chlamydia trachomatis DNA was extracted and amplified by a commercially available Amplicor Chlamydia trachomatis PCR kit(Roche Diagnostics, Branch burg, USA). The clinical characteristics of infertile patients were reviewed and analyzed. RESULTS: The mean age was 31.0 years old, and the mean duration of infertility was 43.4 months. The prevalence rate of endocervical Chlamydia trachomatis in infertile patients was 4.0%(4/101). There was no significant difference in the prevalence rate of Chlamydia trachomatis infection among the different infertility factor groups: 7.1%(2/28) in tubal-peritoneal factor group, 8.3%(1/12) in cervical factor group, and 8.3%(1/12) in unexplained infertility group. Two patients suffered from chronic cervicitis. CONCLUSION: The application of PCR for the detection of Chlamydia trachomatis DNA was a rather rapid and accurate diagnostic method. Therefore, it could be recommended as a diagnostic test applicable to the routine infertility work-up.
Chlamydia Infections* ; Chlamydia trachomatis* ; Chlamydia* ; Diagnostic Tests, Routine ; DNA* ; Female ; Humans ; Infertility ; Polymerase Chain Reaction* ; Prevalence* ; Uterine Cervicitis

No abstract available.
Abdominal Pain ; Adolescent ; Chlamydia Infections ; Chlamydia trachomatis ; Hepatitis ; Humans ; Pelvic Inflammatory Disease ; Peritonitis

Pneumonia, which usually requires hospitalization for children, is caused by various pathogens. According to recent surveys, the prevalence of atypical pneumonia caused by Mycoplasma or Chlamydia has increased, especially in preschool children. Also, the evidence has been accumulated that Mycoplasma or Chlamydia infection is associated with asthma including both inception and exacerbation. Therefore, it is important to consider how the clinical aspects of Mycoplasma pneumonia have changed. In particular, Chlamydia pneumonia, which has not been prevalent in Korea, needs greater attention.
Asthma ; Child ; Child, Preschool ; Chlamydia ; Chlamydia Infections ; Hospitalization ; Humans ; Korea ; Mycoplasma ; Pneumonia ; Pneumonia, Mycoplasma ; Prevalence

PURPOSE: Chlamydia trachomatis (C. trachomatis) is a well known cause of non-gonococcal urethritis (NGU). No other microorganism has been shown to cause any larger proportion of the remaining NGU cases. As a possible causative organism of NGU, we wanted to evaluate the detection rate of Mycoplasma genitalium (M. genitalium) and its role in NGU using polymerase chain reaction (PCR). MATERIALS AND METHDS: From June 1998 to July 2000, we examined a total of 116 men. Of these men 70 had symptoms and signs compatible with urethritis and 46 were for normal control. In the patient group, two urethral discharge or swab specimens were collected. One was used for Gram stain to detect Gram negative intracellular diplocci. The other was subjected to PCR for C. trachomatis and M. genitalium. In the control group, urethral swab specimen was used to detect C. trachomatis and M. genitalium by PCR based assay. RESULTS: Gonococcal urethritis (GU) was diagnosed in 14 cases (20.0%). Detection rates of M. genitalium and C. trachomatis in urethritis group were 8.6% (6/70), 18.6% (13/70). M. genitalium and C. trachomatis were detected in 7.1% (1/14), 14.3% (2/14) of GU and 8.9% (5/56), 19.6% (11/56) of NGU. Detection rate of M. genitalium in chlamydia-negative NGU was 11.1% (5/45). No patient positive for M. genitalium had a simultaneous chlamydia infection. In control group with no urethral symptom or sign, M. genitalium and C. trachomatis were not detected at all. Compared with chlamydia- positive NGU, M. genitalium-positive urethritis exhibited higher recurrence rate. CONCLUSIONS: M. genitalium was detected in 8.9% of NGU and 11.1% of non-chlamydia NGU. This study suggests that M. genitalium may be one of the causative organisms in NGU. Further studies will be necessary to define its role in NGU.
Chlamydia Infections ; Chlamydia trachomatis ; Humans ; Male ; Mycoplasma genitalium* ; Mycoplasma* ; Polymerase Chain Reaction ; Recurrence ; Urethritis*

Chlamydia trachomatis(Ct) infection in reproductive tract is one of the most common sexually transmitted diseases at present. However, relatively fewer studies are made on Ct infection in men. The paper reviews the epidemiology of Ct infection in males, Ct infection and male diseases, Ct infection and male infertility, and the detection of Ct infection in men. It aims at providing a theoretical basis and a practical guide for the prevention and control of Ct infection in men.
Chlamydia Infections ; complications ; diagnosis ; Chlamydia trachomatis ; Humans ; Infertility, Male ; etiology ; Male ; Prostatitis ; etiology

Chlamydia trachomatis infection is one of the most prevalent sexually transmitted diseases in males and studies on its pathogenic and immunologic mechanisms are rather limited. Animal models play an important role in studying the pathogenesis, course and treatment of human diseases, and those of male genital tract chlamydial infection are relatively few and not well developed. This article focuses on the chlamydia species, animal species, infection route, infected organ, and infection process of chlamydia, as well as its impact on reproduction, aiming to provide some help for further studies of male genital tract chlamydial infection.
Animals ; Chlamydia Infections ; complications ; transmission ; Chlamydia trachomatis ; Disease Models, Animal ; Humans ; Male ; Reproduction

Objective: To understand the prevalence of Chlamydia trachomatis (CT) infection and its associated factors among asymptomatic outpatients attending sexually transmitted disease (STD)-related clinics in Shenzhen and provide evidence for development of future interventions. Methods: From April 15 to May 16, 2018, a cross-sectional study was conducted and patients attending STD-related Clinics were recruited from 22 medical institutions in Nanshan, Luohu, Bao'an, Longgang, Yantian, and Longhua districts of Shenzhen. After the informed consent from each participant was obtained, social-demographic information was collected through a structured questionnaire and urine samples were collected for CT nucleic acid detection. In addition, logistic regression was used to explore associated factors of CT infection. Results: In asymptomatic outpatients, the prevalence of CT infection was 7.16% (250/3 492). Being single (aOR=2.29, 95%CI:1.65-3.16), without registered Shenzhen residency (aOR=1.49, 95%CI:1.04-2.13), and without previous CT testing in the past year (aOR=2.04, 95%CI:1.03-4.05) were the risk factors of CT infection in asymptomatic outpatients. Among participants without registered Shenzhen residency, 89.25% (2 176/2 438) were college-degree or below, and 51.29% (1 255/2 447) were aged ≤30 years, and the risk of CT infection among those ≤30 years old was 1.73 times higher than those >30 years old (95%CI:1.28-2.34). Conclusions: The prevalence of CT infection was high among asymptomatic outpatients attending STD-related clinics in Shenzhen. Routine CT screening should be carried out for this population, especially for those with sexually active age, being single, with low educational level, and without previous CT testing in the past year. Also, raising their awareness of knowledge and adverse outcomes of CT infection should be considered to promote routine CT screening and timely treatment.
Adult ; Chlamydia Infections/epidemiology* ; Chlamydia trachomatis ; Cross-Sectional Studies ; Humans ; Nucleic Acids ; Outpatients

Animals ; Mice ; Chlamydia muridarum ; Mice, Inbred BALB C ; Antigens, Bacterial ; Chlamydia Infections