1.Effects of Electroacupuncture Combined with Repetitive Transcranial Magnetic Stimulation on the Expression of Nestin in Neural Stem Cell after Focal Cerebral Ischemia in Adult Rats
Guofu HUANG ; Xiaolin HUANG ; Hong CHEN ; Xiaohua HAY
Chinese Journal of Rehabilitation Medicine 2009;24(5):390-393
Objective: To investigate the influence of electroacupuncture (EA) combined with repetitive transeranial magnetic stimulation(rTMS) on the temporal profile of nestin expression after induction of focal cerebral isehemia in adult rats and to explore the mechanism of EA combined with rTMS in treating ischemic brain injury. Method: The model of transient focal ischemia was produced by occlusion of middle cerebral artery. Seventy-five Wistar rats were randomly divided into normal group, model group, EA group, rTMS group and EA +rTMS group. The neurologic impairment rating and ability of learning and memory were observed at the 7th、14th and 28th d after infarction respectively. Meanwhile, Western blotting was used to observe the number of nestin expression positive cells. Result: Nestin-positive cells were found in cortex, subgranular zone (SGZ), subventricular zone (SVZ) of the ipsilateral side at different time points after cerebral isehemia. The number of nestin-positive cells peaked at the 7th d, began to decrease at the 14th d and was significantly higher in EA+rTMS group than that in model group (P<0.05), then almost reached normal at the 28th d. The improvement of neural motor function deficits as well as the indexes of learning and memory were more obvious in EA+rTMS group compared with model group (P<0.01, P<0.05). These effects were most obvious in EA+rTMS group compared with the EA and rTMS group (P<0.05). Conclusion: EA and rTMS possess the potency of building up and can increase the number of nestin-positive cells in some brain regions after focal cerebral ischemia, which might be one of the important mechanisms of EA combined with rTMS in treating ischemia brain injury.
2.Balance Control Comparison between Subjects with and without Non-specific Low Back Pain
Bin XIE ; Chun LUO ; Rongli WANG ; Ninghua WANG
Chinese Journal of Rehabilitation Medicine 2009;24(5):394-398
Objective: To compare the balance ability between normal people and non-specific low back pain (nsLBP) patients and explore the relationship between balance ability and muscle function in nsLBP patients. Method: Ten nsLBP patients as nsLBP group and 10 age and gender-matched healthy control subjects as control group were investigated. Posturography on balance platform and surface electromyography (sEMG) were performed to assess all the subjects' function of equilibrium and muscle activities of erector spinea(ES), muhifidus(MF), abdominal external oblique (EO), hamstring (HS) and maximal gluteus (MG) bilaterally. Result: The nsLBP subjects had greater sway on anterior-posterior direction (Y-speed and Y-extension, P=0.05) on feet-together posture and bigger main axis (P=0.023) on nature standing with eyes closed when compared with controls. The iEMG ratios of right MG in nature standing (eyes closed)/ nature standing (eyes open) and feet-together (eyes open)/nature standing (eyes open) in control group were significant higher than that in nsLBP group (P=0.03 and P=0.013). Conclusion: Balance evaluation combined with sEMG measurement on trank and lower limb muscles provided some quantitative information about functional deficits such as pestural control and muscle activities in nsLBP patients. This relationship should be emphasized in prevention and rehabilitation of nsLBP.
3.The result of rehabilitation nursing of the patients with total hip replacement
Chinese Journal of Rehabilitation Medicine 2001;16(2):120-121
Objective:To understand the effect and significance of rehabilitation nursing of the patients with total hip replacement. Method:In view of the rehabilitation nursing procedure, functional training before and after the operation were performed in 34 cases with total hip replacement. Result:21 cases made completely recovery; 9 cases complete independent living ;3 cases almost independent living; l case partial dependent, and no complications. Conclusion: Scientific rehabilitation nursing plan can decrease the incidence rate of complications after the operation and promotes functional recover to patients with total hip replacement.
4.Isolinetic test on evaluation of manipulation therapy for frozen shoulder
Li WAN ; Jilin LIU ; Chunjian CHEN
Chinese Journal of Rehabilitation Medicine 2001;16(2):104-106
Objetive: To study the result of manipulation therapy(MT) for frozen shoulders. Method: Before and after MT, the parameters of involoved shoulder extensors and flexors , abductors and adductors were isokinetically recorded on 20 patients with frozen shoulder twice. Result: Compared with the parameters measured pre-therapy most of those factors measured increased significantly afterwards (P<0.01 ). Conclusion:Effect of MT on frozen shoulder are satisfactory and ROM are accurate and reliable.
5.The application significance of intensity/time curves on the evaluation of operation on prolapsed lumbar intervertebrai disc
Chinese Journal of Rehabilitation Medicine 2001;16(2):98-100
Objective: In order to discuss the application value of intensity/time(L/T) curves on the rehabilitation assess ment of prolapsed lumbar intervertebral disc. Method: 244 I/T curves of 111 cases including musculus tibialis anterior、 musculus fibularis longus、musculus extensor hallucis longus were measured. 56 cases were operated. Result: In the 11- 1cases, 24cases were normal, 83 cases were partial degeneration, 4 cases were complete degeneration, the positive ratio was 78.38%. The I/T curves in 56 operated cases, 4 cases were complete degeneration, 45 cases were partial degeneration, 7 cases were normal. In 87.50% cases the I/T curve accorded with operation. In 244 I/T curves, 115 curves were normal, 125 curves were partial degeneration, 4 curves were complete degeneration. The positive ratio were 52.05%.Conclusion: The application value of L/T curves was significant on the rehabilitation assessment of prolapsed lumbar intervertebral disc.
6.Microsurgery and rehabilitation technique in the treatment of avascular necrosis of the femoral head
Chinese Journal of Rehabilitation Medicine 2001;16(2):95-97
Objective :To investigate a new method and its clinical results in the treatment of avascular necrosis of the femoral head in young adults. Method:The necrotic bone was removed and iliac periosteum and bone with vascular pedicle was transplanted in 25 cases (28 hips) ,age 12-42 years old in this group. Rehabilitation technique were applied after surgery. The time of follow up was 3-9.5 years. To evaluate the results, we used the standard score recommended by Society of Osteonecrosis in Chinese Medical Association. Result:16 cases were excellent,7 cases good, and 2 cases fair. The rate of excellent and good was 92%. Conclusion:Transplantation of iliac periosteum and bone with vascular pedicle has the effect on revascularization and new bone formation, which following with rehabilitation methods may promote the reconstruction of the necrotic femoral head and prevent it to collapse. Thus the pathogenesis process had been stopped.
7.Effects of high frequency ventilation diaphagm pacemaker in aged patients with cor pulmonale
Changshun FENG ; Haili LIN ; Yuan YUAN
Chinese Journal of Rehabilitation Medicine 2001;16(2):90-91
Objective: To find out an effective way of the rehabilitation treatment in aged patients with cor pulmonale.Method: 30 cases of aged patients with cor pulmonale in rehabilitation stage were treated with high frequency ventilation diaphagm pacemaker(HDP). Result:The PaO2 and lung function were significantly improved and the level of the plasma endothelin - 1 was significantly lowered after the rehabilitation treatment. Conclusion: HDP is a safe and effective way to patients with cot pulmonale for convalescent treatment.
8.An experimental study of the myogenic components of knee joint contracture
Guoxin NI ; Li SU ; Junkai TANG
Chinese Journal of Rehabilitation Medicine 2001;16(2):80-81
Objective:To differentitate the myogenic from arthrogenic component of knee contracture resulting from being immobilized in extension for 4 weeks. Method:Ten rabbits were used as experimental animals. The right hindlimbs were immobilized with knee in extension for 4 weeks, while the left severed as controls. The range of motion ( ROM ) of both knees were measured before and after myotomy. Result:In immobilized and control hindlimbs, the mean ROM of the knee were 79.5°and 138.5°, respectively. The gain of ROM after myotomy in immobilized and control hindlimbs were 8.7° ±0. 45°, 11.6° +0.58°, respectively. Only 14.75% of the limitation of motion in ROM were accounted for by the myotomy component. Conclusion:After immobilizing for 4 weeks, the ROM of knee was significantly limited. However, the myogenic part was small and not different from normals.
9.Effects of intensive controlled training of scapula for the pain of shoulder in patients with hemiplegia
Chinese Journal of Rehabilitation Medicine 2001;16(1):37-39
Objective: To discuss the effects of prevention and treatment of intensive controlled training of scapula for the pain of shoulder in patients with hemiplegia. Method:65 stroke patients werer randomly divided into treatment group (35 cases) and control group( 30 cases). All of them received routine rehabilitation. The treatment group was intensive trained on scapula control. Result: In the treatment group the pain of shoulder and function of upper- limbs were signficantly improved,as compare with control group. Conclusion:It's indicated that the intensive controlled training of scapula was effective for prevention and care of the pain of shoulder in hemiplegia.
10.A clinical study of immune state on severe traumatic brain injury
Jianhong ZHANG ; Jianzhong FAN ; Zhencai ANG
Chinese Journal of Rehabilitation Medicine 2001;16(1):30-32
Objective: To measure the level of T-lymphocyte subsets and immunoglobulin in severe traumatic brain injury and to explore the clinical significance. Method: 48 cases with severe traumatic brain injury were measured in T-lymphocyte subsets and immunoglobulin of vein blood before and after the rehabilitation therapy. By comparing with the control group and combining clinical evaluation to analyze the immune functional state in the state of TBI and the prognosis. Result:The cellular and humoral immune were inhibited distinctly. The level of CD3 + ,CD4 + ,CD4 +/CD8 +, IgG and IgA of TBI group were lower than the level of the control group. In prognosis, the early immune state of severe disability+vegetable state group was inhibited more seriously than good recovery + mild disability group. Conclusion: The cellular and humoral immune of severe traumatic brain injury were in inhibited state. The severe inhibition of immune, the worse the prognosis.