OBJECTIVETo search for the applications of the dermal vault in mammaplasty.

METHODSThe dermal vault was planned as large as possible according to the degree of the macromastia and mammaptosis. The residual gland was sculptured and fixed with the dermal vault in order to reconstruct the protrude, pliable and living breasts.

RESULTSThe 27 cases (53 breast) were performed with this technique. The result is satisfactory and there are no complications.

CONCLUSIONIt is a good method to use the dermal vault as a sculpturing and fixing material in mammaplasty. The breasts formed are projecting, pliable and moveable. The scar is not apparent and the result is persistent.

Adult ; Breast ; pathology ; Female ; Humans ; Mammaplasty ; methods

OBJECTIVETo obtain postoperative desirable appearance of the deformed breast we apply Mckissock reduction mammaplasty technique in treatment of giant benign breast tumor.

METHODSAccording to the principle of Mckissock reduction mammaplasty technique, we design a special incision to remove the tumor in company with the proceeding of mammaplasty.

RESULTS11 cases of operation with satisfactory results for giant benign tumors have been performed since 1993.

CONCLUSIONSStandard reduction mammaplasty technique has turned out to be an effective remedy for giant tumor spoiling the appearance of the breast.

Adolescent ; Adult ; Breast Neoplasms ; surgery ; Female ; Humans ; Mammaplasty ; methods ; Middle Aged

OBJECTIVETo evaluate the feasibility of growing tissue-engineered cartilage using chondrocytes seeded onto a biodegradable porous bioceramic, the beta-tricalcium phosphate (beta-TCP).

METHODSA porous bioceramic template of beta-TCP was created in the shape of a disc. Chondrocytes isolated from rabbit articular cartilage were seeded on the beta-TCP template and then kept in rotatory cell culture system (RCCS) for 1 week prior to subcutaneous transplantation into athymic mice. The three-dimensional structure was well-maintained 16 weeks after implantation. After 4, 8, 16 weeks, the specimens were harvested and examined macroscopically, histologically and immunohistochemically.

RESULTSGross morphological and histological analysis of the specimens from the chondrocyte-beta-TCP complex demonstrated new cartilage construction. The overall configuration of the experimental specimens closely resembled the structure of beta-TCP template.

CONCLUSIONThese findings suggest that porous bioceramic (beta-TCP) is a good "matrix" for chondrocyte, and can be used for cartilage engineering.

Animals ; Calcium Phosphates ; pharmacology ; Cartilage ; growth & development ; transplantation ; DNA ; analysis ; Female ; Glycosaminoglycans ; analysis ; Immunohistochemistry ; Mice ; Mice, Nude ; Tissue Engineering

OBJECTIVETo study the histocompatibility of three bio-derived bones.

METHODSAfter treatment with different physical and chemical method, three bio-derived bones, the composite fully deproteinized bone (CFDB), partially deproteinized bone (PDPB) and partially decalcified bone (PDCB) were implanted into rabbits. The toxicity, immune response and subperiosteum osteogenesis of CFDB, PDPB and PDCB were studied through gross observation, serum antibody measurement, evaluation of local cellular immune response and HE staining.

RESULTSThe study showed that CFDB, PDPB and PDCB had no toxicity. They could conduct peripheral tissue to grow into them and had no harmful effect on subperiosteum osteogenesis. They could also promote cartilage and osteoid tissue derived from periosteum to calcify to new bone, and combine with the peripheral bone. The degree of immune response caused by them was in the sequence of PDCB > PDPB > CFDB.

CONCLUSIONSThe three bio-derived bones, CFDB, PDPB and PDCB have good histocompatibility.

Animals ; Antibodies ; blood ; Bone Transplantation ; Bone and Bones ; immunology ; Female ; Histocompatibility ; Histocompatibility Testing ; Male ; Rabbits ; Tissue Engineering

OBJECTIVETo investigate a new operation of breast reduction for gynecomastia.

METHODSIn the past 5 years we treated 42 cases (80 sites) of gynecomastia with the double-ring incision, a supra-lateral derma-mammary pedicle of the nipple and areola and the tumescent technique.

RESULTSThe tumescent anesthesia was effective. The operation was easily performed with slight injury and less bleeding. It was safe and the patients recovered quickly. 100 to 500 grams tissue was resected from one breast. There have been no severe postoperative complications, such as nipple or areola necrosis. Follow-up from 3 to 48 months showed satisfactory results except that there was mild scar hypertrophy on the incision around the areola.

CONCLUSIONSThe new operation for gynecomastia with the double-ring incision, a supra-lateral derma-mammary pedicle of the nipple and areola, and the tumescent anesthesia is a good, reliable and convenient technique.

Adolescent ; Adult ; Breast ; surgery ; Gynecomastia ; surgery ; Humans ; Male

OBJECTIVETo explore the feasibility of one-stage repair of hypospadias using scrotal septal skin flap based on peri-meatus dartos fascia.

METHODSNine patients were repaired by this method.

RESULTSAll patients achieved good results without urethral fistula or stricture. The angle of the penis to the scrotum is normal.

CONCLUSIONThe flap has reliable blood supply and the flap creation is easy. It is a simple, convenient and effective method for one-stage repair of hypospadias.

Adolescent ; Child ; Child, Preschool ; Humans ; Hypospadias ; surgery ; Infant ; Male ; Surgical Flaps

OBJECTIVETo introduce an improved technique for Macrocheilia. The traditional technique for macrocheilia with direct suture and Z-plasty was improved to decrease postoperative complications, e.g. dynamic abnormality, obvious scar and recurrence due to scar contraction.

METHODSOutside of the new commissure, a triangle flap of the upper lip vermilion was designed, created and inserted to the lower lip. The orbicularis oris muscle was anatomically replaced. Skin Z-plasty was made with triangle flap transferring from the upper to the lower instead.

RESULTSSince August 1985, the new technique has been used in 12 cases of Macrocheilia. All the patients obtained satisfactory results with nice configuration and good function without dynamic abnormality and obvious scar.

CONCLUSIONThe new technique is a more reasonable method for macrocheilia with nice configuration, good function and fewer complications.

Child ; Child, Preschool ; Female ; Humans ; Lip ; abnormalities ; surgery ; Lip Diseases ; surgery ; Male ; Reconstructive Surgical Procedures ; methods

OBJECTIVETo study the biodegradation process of the bioabsorbable mini-plate (LactoSorb) and its influence on bone healing.

METHODS15 mature New Zealand White Rabbits were selected as the experimental animals. The bilateral zygomatic arch were fractured using a fissure bur. One side was fixed with the bioabsorbable mini-plate and the other side was fixed with Titanium mini-plate as a control. 5 animals were killed after 4, 12, and 24 weeks post operation respectively for radiographic and histologic study.

RESULTSAt 4 weeks, the absorbable plate changed from transparent to opaque and its dimensions was enlarged. The bone gaps of both groups were filled with new bone. No inflammatory cells were found in both groups. At 12 weeks, the absorbable plate broke to small pieces or particles, its dimensions reduced greatly but the outline could still been recognized. The bone continuity had been reestablished in both groups. At 24 weeks, the absorbable plate was resorbed completely. Only the residual screw could be seen in the screw hole. Complete bone healing was seen in both groups. No histological differences of bone healing were found at this stage.

CONCLUSIONThe absorbable plate demonstrates excellent biocompatibility. No adverse local inflammatory reactions were found during the plate was absorbed gradually. In the non-weight baring area, the absorbable plate provides the same fixation stability as that of the metal plate.

Absorption ; Animals ; Bone Plates ; Female ; Fracture Fixation, Internal ; instrumentation ; Male ; Rabbits

OBJECTIVETo introduce an operation for fingertip reconstruction.

METHODSThe vascularity of the reverse dorsal island flap is augmented by performing an arteriovenous anastomosis between the dorsal vein in the flap and a digital artery at the fingertip. The flap was used in ten patients for reconstruction of their fingertip defects.

RESULTSAll the ten flaps survived and the appearance was good.

CONCLUSIONThe method is easy except for the necessity of performing standard microvascular surgery. The flap is a good option for repairing fingertip defects.

Adult ; Female ; Fingers ; surgery ; Humans ; Male ; Microsurgery ; methods ; Surgical Flaps

OBJECTIVETo study the injury process of the skin due to expansion.

METHODSNew Zealand rabbits were divided into 4 groups: rapid expansion and slow expansion as well as two control groups. The changes of skin TGF-beta 1 were observed immediately after expansion and at 1, 12, 24 weeks after expansion. Immunohistochemistry and in situ hybridization technique were applied.

RESULTSTGF-beta 1 increased in the skin immediately after expansion. In groups of rapid expansion, TGF-beta 1 increased faster and then decreased also faster than slow expansion groups. The results from immunohistochemistry and in situ hybridization were almost same.

CONCLUSIONExpansion resulted in skin injury. Rapid expansion injured the skin more seriously than slow expansion. TGF-beta 1 may be the main regulating factor to repairing process.

Animals ; Dermatologic Surgical Procedures ; Immunohistochemistry ; In Situ Hybridization ; Rabbits ; Time Factors ; Tissue Expansion ; Transforming Growth Factor beta ; analysis ; physiology