Objective To develop and validate a qual it y of life(QOL) scale for the Chinese patients with uterocervical cancer (QOL-UC C). Methods Based on the internationally accepted de finition of QOL and the clinical characteristics of uterocervical cancer as wel l as the existing QOL scales, we designed the QOL-UCC. Then 113 patients were r ecruited and the reliability, validity and feasibility of the scale were tested. Results It was shown that the QOL-UCC had good reli ability, validity and feasibility. Conclusion QOL-U CC is a reliable and valid instrument for evaluation of the QOL in Chinese pa tients with uterocervical cancer.

Objective To study the effects of exerci se on heart rate variability (HRV) in elderly patients with old myocardial infarct ion (OMI). Methods Fourty-three patients were recrui ted and divided into an exercise group (24 cases) and a control group (19 cases) . All the patients were given conventional treatment, with those in the exercise group being administered with adequate exercise in addition. Twenty-four hour Holter taper and ultrasonic cardiogram were performed before and at the end of t he 1 month exercise program, respectively, for HRV analysis and cardiac function assessment. Results Before the exercise,HRV and card iac function of senile patients with OMI were significantly lower than those of the controls( P 0.05). Conclusion Exercise can sign ificantly improve the cardiac function of elderly patients with old myocardial i nfarction.

Objective To study the effect of con tinuous passive motion (CPM) on joint function after arthroscopy in the knee jo int. Methods Arthroscopy examinations and operations were performed in 53 patients. They were divided into study and control groups based on the use or not of CPM immediately in the postoperative period. The cont rol group consisted of 25 patients treated without postoperative CPM and the stu dy group consisted of 28 patients treated with CPM postoperatively. Range of mot ion (ROM) and the comprehensive function score of the knee joint were evaluated preoperatively, at discharge and at three months after operation. Results There were statistically significant differences in the f unction score of the knee joint between the two groups at discharge. The mean f lexion and extension in the study group were 90.64??16.57? and -0.71??3.78 ?, respectively, compared to 69.40??15.17? and -4.32??4.71? in the contro l group. The mean of the comprehensive function score of the knee joint in the c ontrol group were 11.24.compared to 8.89 in the study group. Seventy-five perce nt (21 cases) of the patients in the CPM group and 24% (6 cases)of patients in t he control group had achieved 90? of flexion at the time of hospital discharge. Conclusion CPM had enhanced the therapeutic effects of arthroscopy in the knee joint and shortened the length of stay of the patie nts in the hospital. Further investigation is needed for evaluating the long-te rm effect of CPM.

Objective To study the methods of clinic al diagnosis and treatment of chronic lumbar pain induced by chronic compartment s yndrome. Methods Thirty-nine patients with chronic lumbar pain induced by chronic compartment syndrome were recruited. Their diagno sis was confirmed by physical examination and measurement of of lumbar muscle in tra-compartment pressure. Micro-invasive opening decompression of the lumbar c ompartment was performed for treating these patients. Therapeutic exercises of t he lumbar and abdomen muscles were administered 2-days after operation. Results After treatment, the symptoms were significantly r elieved, distance of walk in creased as compared with those before operation. Th e ranges of trunk flexion and extension were increased. A comparison with the pr etreatment showed that the lumbar muscle intra-compartment pressures at rest du ring movement and 6 min after movement were decreased(6.6?0.7 vs 11.1?0.7),(16 0.3?11.15 vs 188.1?12.08)and(6.9?0.8 vs 14.1?1.2)mmHg, respectively ( P

Objective To determine if TENS applicati on for 60 min twice daily, over a short period of time(3-day), could have cumula tive analgesic effects on another type of pain induced by heat. Methods Nineteen elder normal subjects, aged 60 to 85, were randomly allocated into a TENS and a placebo group. Sixty minutes of TENS (200ms in pu lses at 100Hz with 2 ～ 3 times sensory threshold intensity) or placebo stimulat ion was applied to four acupoints around the knee joint twice daily over a 3-da y period (=6 sessions in total). Heat pain threshold was measured using the Med oc TSA-2001 device before, during and after TENS or placebo stimulation to each subject. The results obtained were analyzed using repeated measures ANOVA. Results By the end of 6 treatment sessions, there was a significant increase in the pre-stimulation heat pain threshold, from 46.9℃ i n session 1 to 48.6℃ in session 6, or by 1.7℃ in the TENS group. Conclusion The existence of such a cumulative antinociceptive eff ect, as denoted by a significant rise in the heat pain threshold before TENS in session 1 when compared with that in session 6, suggested possible plastic chang es in the nervous system in the TENS group.

Objective To study the effect of rehabil it ation training on the expression of S-100, GFAP and Nestin in the cortex of cer ebrally infarcted rats. Methods Sixty Sprague-Dawle y rats were used. Experimental cerebral infarction was caused in all the rat s. 24 hours after the infarction, all the rats were randomly divided into 3 grou ps: a rehabilitation group, an immobiliaztion group and a control group. The rat s in the rehabilitation group were given balancing, grasping, rotating and walki ng exercises everyday, while those in the immobilization group were immobilized in cages. The rats in the control group was without any treatment. Immunohistoc hemical technique was used to detect the S-100, GFAP and Nestin expression at t he time points of 24 hours, 1, 2, 3 and 4 weeks after infarction, respectively. Results S-100, GFAP and Nestin expression were foun d around the infarcted cortex. The response increased as the extension of the su rviving time. The immunohistochemical reaction in rats in the rehabilitation gro up was stronger than that in the immobilization group. Conclusi on Rehabilitation training can activate astrocytes, which could impr ove the internal environment, protect the neurons and promote repairing of neuro n.

Objective To get more diagnostic informa ti on from the acute cerebral infarct, We used1HMRS and TCD to investigate the r elationship between the metabolites in the infarct, the infarct volume, blood f low velocity and blood flow to the infarct, and the clinical neurologic deficit. MethodsFifteen patients with acute cerebral infarct underwent1HMRS and TCD examinations. Clinical neurologic deficit score was c ollected from every patient record at the time of the1HMRS and TCD study. Inf arct volume (V/ml) was determined with machine software automatically. A PRESS a cquisition was used for1HMRS. The peak areas of N,Lac,Cr,Cho in the lesi on region were compared with those in the contralateral side. TCD was performed for measuring Vs, Vm of encephalic blood vessels on both sides, and the responsi ble cerebral blood flow was estimated by Vs. ResultsT here were significant decrease of N,Cr,Vm and ECBF in the lesion region when c ompared with the contralateral side( P

Objective To explore the effect of intra ve nous irradiation of low energy He-Ne laser on plasma endothelin(ET) levels in p atients with acute cerebral infarction (ACI). Methods Eighty-five patients with ACI were randomly divided into two groups: In group s I, the patients were treated with low energy He-Ne laser intravenous irradiat ion combined with conventional treatment (group ILIB);In group II, the patients were only received the conventional treatment (conventional control group). The levels of plasmal ET were measured using radioimmunoassay before and 10, 20 days after the treatment, simultaneously 39 healthy subjects were examined for ET le vels and served as the normal control group. Results Before treatment, the plasmal ET level of ACI was significantly higher than th at of normal control group ( P 0.05). ConclusionIt was suggested that intravenous irradiation therapy with low energy He-Ne laser could inhibit ET release and facilitate the recovery of ACI patients.

Objective To investigate the effect of B TX -A block by insulative needle to release the spasticity in cerebral palsy. MethodsFrom June 2000 to November 2002, 47 children wit h spastic cerebral palsy aged 2 to 15 years old, averaged( 6.32?2.52) years o ld were divided into an experiment group and a control group. The 33 children in the experiment group were blocked with BTX-A by insulative needles. The other 14 children in the control group were blocked with BTX-A by use of the convent ional syringe. ResultsThe spasticity in the experim ent group reduced to a larger extend than that in the control group, and the th erapeutic effect lasted longer in the experiment group. Conclusi onUsing insulative needle can improve the effect of BTX-A block.

Objective To investigate the effect of m il d hypothermia on the content of Ca 2+、Mg 2+、EAA in rat brain tissue and ET in plasma after acute cerebral infarction. Methods Forty-eight Sprague-Dawley rats were randomly assigned into trial group and control group. Using the method of reformed line-thrombosis,the cerebral in farction models were established. The rats in the trial-group were cooled by mi ld hypothermia for half an hour, while those in the control group were subjected to no disposal. Every group was divided into 4 sub-groups according to the pos t-infarction disposal time. Every sub-group was composed of 6 SD rats and kill ed at the time points of 1 hour,2 hour,4 hour and 8 hour after infarction, respe ctively. Then the content of Ca 2+、Mg 2+、EAA in rat brain tissue an d ET in plasma were measured. ResultsThe post-infar ction content of Ca 2+、EAA and ET of trial-group increased mildly and Mg 2+ reduced very little. There was a significant statistical difference bet ween the trial group and the control group. Conclusion Mild hypothermia may significantly reverse the increase of the content of Ca 2+ and EAA and the fall of Mg 2+ and the increment of ET in plasma as well after acute cerebral infarction in experimental animals. So as a result, m ild hypothermia possesses protective effect on brain.