Tujia ethnic medical science is an important sub-discipline of China's ethnic medicine system, which has rooted in major Tujia ethnic area such as Hunan, Hubei, Guizhou and Chongqing. It has its own theory, medication characteristic and experi-ence towards ethnic drugs. Particularly, in medication incompatibility, it has formed the principle of thirteen or fourteen incompatible medicament of traditional Tujia ethnic drugs, which play a certain role in guiding the usage and compatibility of tens of thousands of herbs. Focusing on the incompatibility that is abided by Tujia medical workers, the essay makes a textual study on the origin of herbs and conducts a preliminary study on the theoretical basis of thirteen or fourteen incompatible medicaments in terms of four properties of drugs and toxic and side-effect by reference to the records on nature and flavor and effectiveness, with a view of providing a preference to improve the incompatibility theory of traditional Chinese medicines and new ideas to further studies on the development and application of traditional ethnic drugs.
China ; ethnology ; Drug Incompatibility ; Medicine, Chinese Traditional

OBJECTIVETo construct and compare the body mass index (BMI) cutoff points for defining overweight and obesity in school-age children and youths with Uygur and Han ethnic backgrounds in Xinjiang, China.

METHODSA total number of 9146 boys and girls in Urumqi, Xinjiang, aged 7-18 years, were recruited by stratifying and clustering sampling from April to June 2004. Demographic and anthropometric data, including body weight and standing height, were collected. Questionnaires and standard methods were used and BMI was calculated by weight/height2. BMI centile curves with age were drawn according to gender and ethnicity, using LMS software (Tim cole and Huiqi Pan) which were making the centile curves passing through 25 kg/m2 and 30 kg/m2, and 24 kg/m2 and 28 kg/m2 at age of 18 for overweight and obesity respectively.

RESULTSThe age and sex specific BMI centile curves were drawn for children with Uygur and Han ethnicities. Data showed that BMI increased with age. The centile of BMI curves, P94.46 and P99.58 for Uygur boys, P92.44 and P99.64 for Uygur girls, P85.05 and P97.26 for Han boys, P90.92 and P99.03 for Han girls, which passing through 25 kg/m2 and 30 kg/m2 by IOTF recommendation at age 18, were constructed. Under the basis of WGOC recommendation, the points that passing through 24 kg/m2 and 28 kg/m2 at age 18 were P90.54 and P98.86 for uygur boys, P86.96 and P98.77 for uygur girls, P78.98 and P94.72 for Han boys, P86.15 and P97.56 for Han girls. The BMI cutoff points for defining overweight and obesity were suggested.

CONCLUSIONTo the best of our knowledge, the present study established the BMI cutoff points for Uygur ethnic school-aged children and youths for identifying overweight and obesity. There was ethnic difference in the BMI distribution with age. We recommended using the BMI cutoff points proposed by the current study to identify those overweight and obese children in Urumqi.

Adolescent ; Body Mass Index ; Child ; China ; epidemiology ; ethnology ; Female ; Humans ; Male ; Obesity ; epidemiology ; ethnology ; Overweight ; epidemiology ; ethnology

OBJECTIVETo analyze the population genetics characteristics of mitochondrial DNA (mtDNA) in Gelao, Mulao, Maonan ethnic groups from Guizhou.

METHODSMinisequenceing and restriction fragment length polymorphism (RFLP) were used to analyze 12 single nucleotide polymorphism (SNPs) of mitochondrial DNA in the 3 ethnic groups.

RESULTSA total of 30 haplotypes were detected in 156 samples. The distribution of H1, H23 had differed between Mulao, Maonan and Gelao, respectively, and so did M7 among the three groups. The difference was statistically significant (P < 0.05). Mulao, Maonan had respectively differed from Gelao and the difference was also statistically significant (P < 0.05).

CONCLUSIONThere was a great similarity in the distribution of haplotypes of the mtDNA among the three ethnic groups, except for some difference in the distribution of certain haplotypes.

Asian Continental Ancestry Group ; ethnology ; genetics ; China ; ethnology ; DNA, Mitochondrial ; genetics ; Humans ; Male ; Pedigree ; Polymorphism, Genetic

Adult ; Asian Continental Ancestry Group ; statistics & numerical data ; China ; epidemiology ; Humans ; Hypertension ; ethnology ; Metabolic Syndrome ; ethnology

OBJECTIVETo investigate obesity, overweight and related factors of Kazakh children aged from 6 to 13 years old in Yili, Xinjiang.

METHODSWith stratified cluster sampling method, 2438 Kazakh children aged 6 - 13 from eight elementary schools were recruited from the Yili Kazakh autonomy region from May to June in 2009. Height, weight, blood pressure, waist circumference and hip circumference were measured. Body mass index (BMI) value was used to determine overweight or obesity. The overweight and obesity distribution pattern of gender, age (6 - 7, 8, 9, 10, 11, 12, 13 - 14 years old group) and region (city, county and countryside) was analyzed. Logistic regression analysis was used to analyze the risk factors of overweight or obesity.

RESULTSThe prevalence of obesity and overweight in Yili Kazakh autonomy region was 1.64% (40/2438) (male: 1.62% (20/1232), female 1.66% (20/1206) (χ(2) = 0.69, P = 0.41)), and 5.13% (25/2438) (male: 4.79% (59/1232), female 5.47% (66/1206) (χ(2) = 0.59, P = 0.44)), respectively. The obesity prevalence of 6 - 7 year-old children was 3.72% (8/215), 2.30% (10/435) for 12 year-old group and 2.19% (6/274) for 13 - 14 year-old group. The difference of obesity and overweight prevalence among different age groups was significant (χ(2) = 14.29, P = 0.04). The prevalence of overweight was 8.77% (35/399), 6.92% (74/1069), 1.65% (16/970) (χ(2) = 42.09, P = 0.00) in city, county and countryside. And the prevalence of obesity was 2.75% (11/399), 2.43% (27/1069), 0.30% (3/970) (χ(2) = 18.13, P = 0.00) in city, county and countryside. Logistic regression analysis showed that children with family obesity history (OR = 2.73, 95%CI: 1.42 - 5.22) and culture level of fathers (OR = 1.65, 95%CI: 0.29 - 9.25) were independent risk factors of obesity. There was a correlation between blood pressure and waist-to-hip rate (r = 0.10, P = 0.00). Moreover, the correlation existed between systolic pressure (r = 0.47, P = 0.00), diastolic blood pressure (r = 0.37, P = 0.00) and BMI. Correlation existed between waist circumference (r = 0.81, P = 0.00), hip circumference (r = 0.78, P = 0.00) and BMI.

CONCLUSIONThere is no sex difference of overweight and obesity prevalence in Kazakh children aged from 6 to 13 year-old. Both family history of obesity and culture level of the fathers are factors of obesity and overweight to Kazakh children.

Adolescent ; Child ; China ; epidemiology ; Female ; Humans ; Male ; Obesity ; ethnology ; Overweight ; ethnology ; Prevalence ; Risk Factors

OBJECTIVETo investigate the genetic polymorphisms of 15 short tandem repeat (STRs) in Guilin Han population.

METHODSDNA was extracted by Chelex method, and 15 STRs were analyzed using AmpFISTR Identifiler kit.

RESULTSFour rare alleles, namely FGA * 10, D2S1338 * 10, D3S1358 * 16.2 and D3S1358 * 17.2, were observed. The combined match probability and exclusion probability for the 15 STRs were 2.89 x 10(-17) and 0.9999993, respectively.

CONCLUSIONThese STRs have good discrimination power and exclusion probability in Guilin Han population.

Asian Continental Ancestry Group ; ethnology ; genetics ; China ; ethnology ; Female ; Humans ; Male ; Microsatellite Repeats ; Polymorphism, Genetic

Objective: To study the prevalence of musculoskeletal disorders (MSDs) and related factors in female greenhouse workers. Method: A questionnaire survey was conducted among 851 female greenhouse workers in Shandong province in 2015. Results: The incidence of MSDs among the female greenhouse workers was 82.79%. For the MSDs in female greenhouse workers, the top four affected body sites were low back (65.82%), knees (49.10%), neck (25.75%) and shoulder (23.47%). Multivariate logistic regression analysis showed that age ≥50 years (OR=2.098, 95%CI: 1.353-3.252), working years ≥20 (OR=1.703, 95%CI: 1.116-2.599), repetitive work (OR=1.903, 95%CI: 1.183-3.061), standing for prolonged time (OR=2.902, 95%CI: 1.183-7.120) and frequent slightly bending down (OR=2.979, 95%CI: 1.823-4.867) were the main risk factors for MSDs in female greenhouse workers. Aiding tools was the protective factor (OR=0.400, 95%CI:0.229-0.697). Conclusions: The findings showed a relatively higher prevalence of MSDs in female greenhouse workers. It is necessary to take appropriate measures to prevent and control the incidence of MSDs in female greenhouse workers.
Agriculture ; China/epidemiology* ; Female ; Humans ; Musculoskeletal Diseases/ethnology* ; Occupational Diseases/ethnology* ; Prevalence ; Risk Factors ; Surveys and Questionnaires

Asian Continental Ancestry Group ; ethnology ; China ; epidemiology ; Esophageal Neoplasms ; ethnology ; Female ; Humans ; Lung Neoplasms ; ethnology ; Male ; Middle Aged ; Prevalence ; Retrospective Studies ; Stomach Neoplasms ; ethnology

"Jajie" means antidote in Dai language. As an important part of theories of Dia ethnic medicine, "Jajie" focuses on antidote before treatment. With wide application and exact effect, "Jajie" plays an important role in preventing and treating diseases, especially liver disease, digestive system diseases, metabolic diseases, skin diseases and so on. Therefore, systematic collection, analysis and studies on Dai ethnic medicine "Jajie" is an important content in the development of the theory of Dai ethnic medicine as well as new drugs. This essay briefs the general situation of "Jajie" and the advance of its studies, and gives comments on Jajie's development.
Antidotes ; therapeutic use ; China ; ethnology ; Humans ; Medicine, Chinese Traditional

OBJECTIVETo investigate the type and frequency of mutations in exon 7 of phenylalanine hydroxylase (PAH) gene among children with phenylketonuria (PKU) in Ningxia, China and to provide a basis for the genetic diagnosis and prenatal diagnosis of PKU in this region.

METHODSDirect sequencing of PCR product was performed to analyze the sequences of exon 7 and its flanking introns of 146 PAH alleles in 73 children with typical PKU (39 cases of Hui nationality and 34 cases of Han nationality) in Ningxia.

RESULTSSix mutations were detected, including R243Q (14.4%), R241C (6.8%), IVS7+2T→A (2.7%), L255S (0.7%), G247V (0.7%), and G247R (0.7%). The overall frequency of mutations (missense mutation and splice site mutation) in exon 7 was 26.0% (38/146). The detection rate of R241C mutation was significantly higher in children of Hui nationality than in children of Han nationality(10% vs 3%; P<0.05).

CONCLUSIONSIn Ningxia, R243Q mutation in exon 7 of PAH gene is most common in children with PKU, followed by R241C. The frequency of R241C mutation in exon 7 of PAH gene varies between children with PKU of Hui and Han nationality.

China ; ethnology ; Exons ; Humans ; Mutation ; Phenylalanine Hydroxylase ; genetics ; Phenylketonurias ; genetics