PURPOSE: Diabetic retinopathy (DR) has influence on peripheral retina, and progression of DR is thought to make prolongation of peripheral retinal circulation. However, there has been no study on circulation of peripheral retina. This study is to make a comparision of peripheral retinal microcirculation between control, non-proliferative diabetic retin-opathy (NPDR), and pre-and post-panretinal photocoagulation (PRP) of proliferative diabetic retinopathy (PDR). METHODS: The authors performed the study on 19 control eyes and 68 DR eyes (NPDR 31, PDR 37) and PDR group was subdivided into before and after PRP. The authors measured arm to retinal circulation time (ART), arteriovenous passage time (AVP), venous filling time (VFT) by scanning laser ophthalmoscope in upper temporal retinal vessel in order to evaluate peripheral retinal microcirculation. RESULTS: VFT was 9.4+/-0.3 sec in pre-PRP of PDR, 7.5+/-0.6 sec (p<0.05) in post-PRP of PDR and 6.4+/-2.2 sec in control, 8.17+/-1.90 sec (p<0.05) in NPDR. However, there is no significant difference in ART, AVP. CONCLUSIONS: Patients with NPDR showed prolongation of VFT compared to normal indivisuals. There was shortening of VFT in post-PRP of PDR similar to NPDR. Peripheral retinal circulation time after PRP can be utilized as an indicator of PRP effect.
Arm ; Diabetic Retinopathy* ; Humans ; Light Coagulation* ; Microcirculation ; Ophthalmoscopes ; Retina ; Retinal Vessels ; Retinaldehyde

PURPOSE: Epicanthal folds and epiblepharon which often develop in oriental children are congenital anomalies of eyelids. These may need surgical correction because corneal irritation may develop by medial upper and lower eyelash besides cosmetic problems. V-Y plasty and Mustarde's method are standards for correction of epicanthal folds, but not usually performed because of cosmetic scar formation. METHODS: This study included 26 patients, 52 eyes (19 females, 38 eyes; 7 males, 14 eyes) with corneal irritation due to medial upper and lower eyelash. We performed upper and lower lid blepharoplasty simultaneously and analyzed their results and complications through medical records. RESULTS: Epiblepharon associated with epicanthus tarsalis was found in 22 patients, 22 eyes, epicanthus palpebralis in 4 patients, 8 eyes. At the time of surgery mean age was 7 years old (3.7~10.3 years old). During the follow-up more than 6 months, double fold asymmetry was found in 1 patient, double fold loosening in 1 patient, 2 eyes, lower eyelid undercorrection in 2 patients, 3 eyes. CONCLUSIONS: These findings suggest that simultaneous upper and lower lid blepharoplasty for patients with corneal problems due to medial upper and lower eyelash is more unsatisfactory in the cosmetic result than standard method, but has advantage of less scarring, and thought to be a good method to relieve corneal irritation.
Blepharoplasty* ; Child ; Cicatrix ; Eyelids ; Female ; Follow-Up Studies ; Humans ; Male ; Medical Records