The purpose of this study was to clarify the effects of different frequencies of skipping rope on the elastic components of muscle and tendon in human triceps surae. Six male subjects performed ten rounds of skipping rope. Skipping tempos were with in a range of 100-170 skips per minute (SPM) . The vertical ground reaction force and the surface EMG of triceps surae muscles were recorded during each skipping round. Elastic components of muscle and tendon were estimated by Residual Time (RT : lag time difference between the vanishing point of muscle discharge and disappearance of EMG, and the end of the ground reaction force wave) and RTintegrate (integration of ground reaction force while RT still appears) . RT and RTintegrate at 100 SPM were the smallest values for all jump frequencies. On the other hand, integrated EMG (iEMG) at 100 SPM was the largest value for all jump frequencies. Although RT and RT_integrateprogressively increased as SPM was increased, iEMG correspondingly decreased. Rate in utilization of elastic components of muscle and tendon assessed by RT_integrateat 170 SPM corresponds to 150% at 100 SPM. These results suggest that the rate in utilization of the elastic components of muscle and tendon while skipping rope, depend on jump frequency.

Barrett's adenocarcinoma may occur in multiple sites, and recurrence and metachronous lesions are the major problems with endoscopic resection. Therefore, early detection of such lesions is ideal to achieve complete resection and obtain improved survival rates with minimally invasive treatment. Laser imaging systems allow multiple modalities of endoscopic imaging by using white light laser, flexible spectral imaging color enhancement (FICE), blue laser imaging (BLI), and linked color imaging even at a distant view. However, the usefulness of these modalities has not been sufficiently reported regarding Barrett's adenocarcinoma. Here, we report on a patient with three synchronous lesions followed by one metachronous lesion in a long segment with changes of Barrett's esophagus, all diagnosed with this new laser endoscopic imaging system and enhanced by using FICE and/or BLI with high contrast compared with the surrounding mucosa. Laser endoscopic imaging may facilitate the detection of malignancies in patients with early Barrett's adenocarcinoma.
Adenocarcinoma* ; Barrett Esophagus* ; Humans ; Mucous Membrane ; Recurrence ; Survival Rate

Objective：This study investigated the relationship between posture and voluntary cough strength in healthy people.Methods：The participants were 50 normal adults. We measured cough peak flow (CPF), chest circumferences at maximal inspiratory level and maximal expiratory level, blood pressure, and pulse rate in the supine position, prone position, and prone position with a pillow under the abdomen. The difference between chest circumferences at maximal inspiratory and maximal expiratory levels was calculated and defined as the thoracic expansion difference.Results：CPF and chest circumferences at maximal inspiratory level and maximal expiratory level were significantly higher in the prone position with a pillow under the abdomen than in the supine position. There were no differences in thoracic expansion difference and blood pressure among all the positions. Pulse rate was significantly lower in the supine position compared with the other positions.Conclusion：We concluded that voluntary cough strength would increase in the prone position with a pillow under the abdomen.

Objective：This study investigated the relationship between posture and voluntary cough strength in healthy people.Methods：The participants were 50 normal adults. We measured cough peak flow (CPF), chest circumferences at maximal inspiratory level and maximal expiratory level, blood pressure, and pulse rate in the supine position, prone position, and prone position with a pillow under the abdomen. The difference between chest circumferences at maximal inspiratory and maximal expiratory levels was calculated and defined as the thoracic expansion difference.Results：CPF and chest circumferences at maximal inspiratory level and maximal expiratory level were significantly higher in the prone position with a pillow under the abdomen than in the supine position. There were no differences in thoracic expansion difference and blood pressure among all the positions. Pulse rate was significantly lower in the supine position compared with the other positions.Conclusion：We concluded that voluntary cough strength would increase in the prone position with a pillow under the abdomen.

The present study was performed to ascertain the annual changes in the number and nature of traumatic head injuries that occur in high-school rugby matches, and as an exploratory investigation of approaches to improve safety in the future. It was based on injury reports submitted at the time of injury to the Kansai Rugby Football Union between Apr. 2009 and Mar. 2016. The finding was that the mean number of reported cases of traumatic head injury per year during the three pre-amendment years from Apr. 2009 to Mar. 2011 was 18.0, whereas that during the five post-amendment years from Apr. 2012 to Mar. 2016 was 36.2. Of all the traumatic head injuries, those with the highest numbers and proportions of cases for each of the four factors were as follows: (i) occasion of injury: during a match, 115 (48.9%); (ii) condition of the pitch: grass, 105 (44.7%); (iii) school grade: 2, 104 (44.3%); and (iv) cause of injury: tackling, 115 (48.9%). In addition, the odds ratios (ORs) for brain concussion at post-amendment as compared with pre-amendment and for occurrence on grass as compared with on soil were significant 2.83. An exploratory investigation was conducted to clarify whether different factors are associated with the severity of pre- and post-amendment injuries, but no significant ORs were found. In conclusion, the establishment of guidelines related to brain concussion in 2012 increased the number of reports of injuries due to high-school rugby and had a definite effect on prompt treatment of brain concussions.

The aging population in Japan continues to grow, leading to the emergence of complex issues. To understand the current awareness of these issues among member pharmacies of the Fukuoka City Minami Ward Pharmaceutical Association and promote various initiatives, support tools such as the “Consultation Flowchart” and “Consultation Checklist” were distributed to share information about the elderly with the local comprehensive support center. A survey was conducted to assess the awareness of complex issues and support tools. The survey revealed that about half of the pharmacy pharmacists were aware of the complex issues themselves, but the Consultation Flowchart had a recognition rate of 35.34%, and the Consultation Checklist had a recognition rate of 31.03%. It was also found that pharmacies with higher participation in regional collaboration meetings and a greater number of visits for medication management counseling had higher awareness of complex issues and support tools. To enhance efforts in addressing complex issues, the Fukuoka City Minami Ward Pharmaceutical Association needs to approach pharmacies with limited participation in regional collaboration meetings and a lower number of visits for medication management counseling. Building visible relationships with diverse professions in the community is crucial for improvement initiatives related to complex issues.

BACKGROUND: Studies reported adverse behavioral development including internalizing and externalizing problems in association with prenatal exposure to bisphenol A (BPA) and phthalates; however, findings were not sufficient due to using different assessment tools and child ages among studies. This study aimed to examine associations between maternal serum levels of BPA and phthalate metabolites and behavioral problems at preschool age. METHODS: The Strengths and Difficulties Questionnaire (SDQ) was used to assess behavioral problems at 5 years of age. BPA and phthalate metabolite levels in the first trimester maternal serum was determined by LC-MS/MS for 458 children. Variables used for adjustment were parental ages, maternal cotinine levels, family income during pregnancy, child sex, birth order, and age at SDQ completed. RESULTS: The median concentrations of BPA, MnBP, MiBP, MEHP, and MECPP, primary and secondary metabolites of phthalates, were 0.062, 26.0, 7.0, 1.40, and 0.20 ng/ml, respectively. MECPP level was associated with increase conduct problem risk (OR = 2.78, 95% CI 1.36-5.68) overall and the association remained after child sex stratification, and odds ratios were increased with wider confidence interval (OR = 2.85, 95% CI 1.07-7.57 for boys, OR = 4.04, 95% CI 1.31-12.5 for girls, respectively). BPA, ∑DBP (MnBP + MiBP), and ∑DEHP (MEHP+MECPP) levels were not associated with any of the child behavioral problems. CONCLUSIONS Our analyses found no significant association between BPA or summation of phthalate metabolite levels and any of the behavioral problems at 5 years of age but suggested possible association between MECPP levels and increased risk of conduct problems.
Adult ; Age Factors ; Benzhydryl Compounds ; blood ; Child, Preschool ; Environmental Exposure ; analysis ; Female ; Humans ; Male ; Phenols ; blood ; Phthalic Acids ; blood ; Pregnancy ; Prenatal Exposure Delayed Effects ; epidemiology ; Problem Behavior ; Smoking ; epidemiology ; Socioeconomic Factors