A study on immunogenicity of hepatitis B vaccine produced by NIHE, Hanoi was conducted on 240 children under 1 year old in Nha Trang during 1994-1996. The vaccination schedule was 0, 1, 6 month. Blood sampling was performed at 3, 7, 12 month after vaccination. All children were given 10g/dose. The immunogenicity was following: seroconvertion rates were 82.89%, 96.97% and 97.97% with GMT: 120.69, 473.38 and 258.2 UI/L, respectively. The antibody response rates were the same in 2 groups, but GMT of newborn was higher than on children of 6-12 months old and there was a statistical significant difference.
Immunization ; hepatitis B vaccines ; child