1.Clinical Study on Comparison of Laboratory Check-ups Completed on 126 Patients with Acute Abdomen
Chi NIU ; Longyou ZHANG ; Dongming YU
Journal of Medical Research 2006;0(02):-
Objective To study on comparison of different age group patients with acute abdomen who received laboratory check-ups.Methods 126 patients with acute abdomen were divided into 0.05).2.Of 126 patients,65 cases(51.6%)received abdominal B ultrasonography check-up,among which 41 cases(44.1%)were in
2.Establishment and Implementation of the Evaluation System in Microbiology Experimental Education
Qing-Fang ZHANG ; Nai-Yu CHI ;
Microbiology 2008;0(09):-
"Three-multi" overall evaluation system on the teaching effect of Microbiology experiment,which consisted of multi-aspect,multi-angle and multi-level,was discussed in this paper. The evaluation system showed a remarkable effect in stimulating the leaning interests of students especially.
3.Antihypertensive treatment in the prevention and treatment of ischemic stroke: the J-curve phenomenon
Xianglin CHI ; Yongpeng YU ; Daozhen WANG ; Zhaoqiang ZHANG
International Journal of Cerebrovascular Diseases 2013;21(6):459-468
The J-curve phenomenon in the antihypertensive treatment of cardiovascular disease has had more theoretical and experimental evidence and has been recognized by most researchers.However,there are a few related studies and reports about whether antihypertensive treatment has the J-curve phenomenon in ischemic stroke.It has not yet reached a consensus.This article reviews this phenomenon and expecting it to contribute to the blood pressure mangement of ischemic stroke.
4.Research progress in HIV auxiliary proteins counteracting host restriction factors.
Qian-Qian CHEN ; Qing-Gang XU ; Chi-Yu ZHANG
Chinese Journal of Virology 2014;30(1):84-90
Identification and functional analyses of antiviral restriction factors in hosts have become hot research topics. Four HIV restriction factors, APOBEC3G, Trim5alpha, Tetherin, and SAMHD1, have been identified in recent years. By encoding auxiliary proteins, lentiviruses can counteract host restriction factors. For example, the auxiliary proteins Vif, Vpu, and Vpx of HIV antagonize APOBEC3G, Tetherin, and SAMHD1, respectively. Furthermore, these auxiliary proteins enable the entry of HIV into host cells and influence the replication and pathogenicity of HIV. In this paper, we review the research progress in the functions of the three HIV auxiliary proteins that can antagonize the host restriction factors.
Animals
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HIV
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metabolism
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physiology
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Host-Pathogen Interactions
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Humans
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Viral Proteins
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metabolism
5.Five cases of psychiatric deafness misdiagnosed as sudden deafness.
Hui ZHAO ; Fang-lu CHI ; Tian-yu ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2006;41(5):385-386
Adolescent
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Adult
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Deafness
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diagnosis
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etiology
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psychology
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Diagnostic Errors
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Female
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Hearing Loss, Sudden
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diagnosis
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Humans
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Male
6.Investigation and analysis of professional ethics of clinical medical postgraduates
Ping ZHANG ; Xing WU ; Jiaao YU ; Shi TANG ; Baorong CHI
Chinese Journal of Medical Education Research 2017;16(5):537-540
Objective To understand the cognition of clinical medical postgraduates' professional ethics,in order to provide the basis for the further development of graduate professional ethics education.Methods The survey was carried out among 650 graduate students of the first hospital of Jilin University by self-designed questionnaires.The questionnaires included the general situation and the understanding of professional ethics of medicine.All data were analyzed by SPSS 17.0,using Chi-square test to compare the results in different grades about the understanding of professional ethics.Results In this study,a total of 650 questionnaires were issued,and 629 valid questionnaires were collected with a recovery rate of 96.7%.Most graduates' professional values were in line with the socialist core values.For example,for the attitude of medical workers to accept red envelopes,410 graduate students (65.2%) firmly opposed to accepting this behavior.For the purpose of the study medicine,there was no statistically significant difference among different grades (P=0.273).For the attitude of red paper,the main problem in medical ethics education and the biggest factor for graduates,there was statistically significant difference among different grades (P=0.012,P=0.002,P=0.002,respectively).Conclusion At present,the professional ethics of postgraduates in clinical medicine is in good condition,but still needs to be improved.We can give further education and guidance to students for the problems existing in graduate students of different grades.
7.Study on Silibinin Preformulation
Yu ZHOU ; Xinhua XIA ; Chao LI ; Chi ZHANG
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(5):100-103
Objective To study the physical and chemical properties of silibinin; To lay foundation for optimal formulation design.Methods The high performance liquid chromatography method was used to detect the equilibrium solubility of silibininin in various solutions. The partition coefficients of silibinnin in the n-octalution-water and n-octalution-buffer solution systems were determined by shaking flask method. The destructive tests were carried out on silibinin.Results The equilibrium solubility of silibininin at 25℃ was 1.352 mg/L in water and the largest in acetonitrile, and increased in basic buffer solutions and after adding surfactants, of which sodium dodecyl benzene sulfonate was the strongest in solubilizing ability. The apparent oil-water partition coefficient of silibinnin was 61.39. Silibinnin was unstable in the acidic, basic, oxidizing and reducing solutions.Conclusion The experiment results can provide references for designing new preparations of silibinin.
8.The practice and exploration of the reform of cultivating master degree students of clinical medicine promoted by the synergy of medical education
Ping ZHANG ; Zhiyu YU ; Baorong CHI ; Dedong LIANG ; Ya LIU
Chinese Journal of Medical Education Research 2015;(9):865-867,868
Our university actively carried out the reform and innovation of the training mode of clinical medicine postgraduates . We implemented the standardized training of resident physicians throughout postgraduate training process , and carried out the comprehensive reform of the training mode of cultivating master degree students of clinical medicine and the standard training of resident doctors. Meanwhile, we trained the master degree students with the synergy of medical education and strengthened the cultivation of students' clinical practice ability, to cultivate qualified doctors for the country, and to improve the quality of postgraduate training.
9.The Optimal Fermentation Conditions of Cold-active Cellulase Strain CNY086(Ⅱ)
Liang CHEN ; Nai-Yu CHI ; Qing-Fang ZHANG ;
Microbiology 2008;0(10):-
Based on the research of text (Ⅰ) which determined the fermentation medium, the fermentation condition of CNY086 including temperature, volume, inoculum and inoculum age had been studied by single factor and orthogonal experiment. The optimum temperature, liquid volume, inoculum and seed age were 15?C, 250 mL/500 mL, 15%, 10 h. Under the conditions above mentioned, enzyme activity reached 104.36 U/mL in 5 L fermentor.
10.Breeding and Fermentation Medium Optimization of Cold-active Cellulase Strain CNY086(Ⅰ)
Liang CHEN ; Nai-Yu CHI ; Qing-Fang ZHANG ;
Microbiology 2008;0(10):-
21 cold-active strains which produced cold-active cellulase were isolated from Bohai Bay. One of the strains CNY01 was a kind of Trichoderma viride and its cellulase activity was 67.30 U/mL. Through UV and DES mutation, the strain CNY086 was bred and its cellulase activity was 92.17 U/mL. The strain CNY086 had stable ability to produce cellulase. Through orthogonal experiment, the optimal condition of the fermentation medium had been tested. The suitable medium was that straw power 1.20%, bran 0.70%, (NH4)2SO4 0.50%, KH2PO4 0.55%, in this condition the cellulase activity came to 108.55 U/mL.